GLOBAL POLIO ERADICATION INITIATIVE (GPEI) STATUS REPORT 25 SEPTEMBER 2014 World Health Organization Geneva, Switzerland Rotary International Evanston, Illinois USA Centers for Disease Control and Prevention Atlanta, Georgia USA UNICEF New York, New York USA The boundaries and names shown and designations used on all maps in this document do not imply the expression of any opinion whatsoever on the part of the Global Polio Eradication Initiative spearheading partners (the World Health Organization, Rotary International, CDC or UNICEF) concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. GPEI Partner Status Report - 25 September 2014 EXECUTIVE SUMMARY! Since April 2014, Nigeria continues to have a low incidence of wild poliovirus type 1 (WPV1) cases; stopping all WPV transmission in Africa in 2014 remains a possibility. More than 22 months have passed without detection of wild poliovirus type 3 (WPV3) anywhere. The WPV1 outbreak in Syria (most recent case: 21 January) spread to Iraq (most recent case: 7 April). The outbreak in Central Africa has persisted more than six months, with spread from Cameroon to Equatorial Guinea, and the risk for further spread, as evidenced by cases in eastern Cameroon and positive environmental sampling in Brazil linked to Equatorial Guinea. These events plus the spread from Pakistan to Afghanistan in early 2014 led to the declaration of a Public Health Emergency of International Concern on 5 May; recommendations were extended on 3 August. The WPV1 outbreak in the Horn of Africa has continued, with the latest reported case occurring in August 2014 in Mudug, Somalia among pastoralist families. The WPV1 outbreak in Pakistan centered in the Federally Administered Tribal Areas (FATA) is escalating rapidly; vvaccination of displaced persons at transit points and within host communities has been scaled up immensely. Surveillance performance indicators and/or genomic sequence analysis have provided evidence of lapses in surveillance in most of these countries and many countries in proximity. Afghanistan: Ten WPV1 cases have been reported to date in 2014. For the past year, polio cases occurred primarily in the Eastern Region linked to importation from Pakistan. The occurrence in December 2013 and May 2014 of indigenous-lineage WPV1 cases in the Southern Region, after 20 months without detection revealed continued surveillance gaps. Environmental surveillance recently began at selected sites in several cities and WPV1 was detected for the first time in specimens taken in Kandahar and Nangarhar Provinces in July 2014. Access to children has improved: the programme now has access to the Watapur District in Kunar after four years of exclusion, and Helmand Province, closed to vaccination since March 2014, is once again conducting supplemental immunization activities (SIAs). Inaccessibility again is a relatively small problem (0.55% of targeted population of 8.9M) and primarily limited to the Eastern Region. Although relatively small in number, the proportion of targeted children under 5 years of age missed because of refusals in the Southern Region continues to be the highest globally. Social and cultural norms are a critical barrier, preventing vaccination of newborn, sick, and sleeping children. Pakistan: The outbreak of WPV1 and circulating vaccine-derived poliovirus type 2 (cVDPV2) in FATA has continued to expand since the last report, with Pakistan having recorded 166 cases in 2014 as of 23 September, compared with 28 during the same period last year. The number of reported cVDPV2 cases has decreased in 2014 compared with this time in 2013; the most recent case was in June. Environmental surveillance shows WPV1 transmission to be more widespread than last year. The government’s recent reluctance to actively engage in polio eradication, including delaying the signing of an Islamic Development Bank loan, has contributed to Pakistan’s problems. Despite the major setbacks in Pakistan, some successes have occurred. The program scaledup its already large transit-point vaccination network to reach the large number of children displaced out of North Waziristan because of military actions there. Outside of key reservoirs of FATA, adjoining KP and Karachi, the program is not seeing major outbreaks of polio, despite certain internal WPV importations. The threat of violence against polio vaccination teams and security personnel has continued in parts of Karachi and greater Peshawar. Nigeria: Nigeria has continued to intensify its programme, pushing innovation and accountability, and administering inactive poliovirus vaccine (IPV) SIAs in selected areas to accelerate interruption of WPV transmission. Only six WPV1 cases have been reported in Nigeria so far this year, and WPV3 has not detected for more than 22 months. Since late last year, WPV transmission appears to have been isolated to two areas,: Borno/Yobe and the “Kano transmission zone,” consisting of southern Kano State and adjoining local government areas (LGAs) of Kaduna and Bauchi. Activities are being further intensified in the latter zone, possibly the only Page i GPEI Partner Status Report - 25 September 2014 place in Nigeria now with ongoing WPV1 transmission. At the same time, cVDPV2 transmission has continued, in part because of a strategic decision to focus on WPV elimination early in the year and to delay trivalent oral poliovirus vaccine (tOPV) subnational immunization days (SNIDs) to August and November of this year. Nineteen cVDPV2 cases have been recorded so far in 2014 and environmental surveillance has shown transmission across the north. Ongoing violence and conflict in Borno and Yobe state continue to affect the scope and quality of SIAs. Horn of Africa: The focus of the outbreak in the South/Central Zone of Somalia was brought under control last year, and WPV1 hasn’t been reported in Kenya since July 2013 or in Ethiopia since January 2014. However, the detection of cases among pastoralists in the Mudug Region of Puntland in May, June and August exposes ongoing transmission in rural Somalia while raising the possibility that bordering areas in Ethiopia may also be at risk. The Somalia programme is now taking additional measures to reach pastoralist children. The security situation has not improved in large sections of South Central Somalia, and the upcoming larger military operations could further create opportunities for increased violence against civilian and humanitarian actors Central Africa: Since mid-November 2013, Cameroon has been responding to a WPV1 outbreak after imported WPV1 that had circulated undetected for more than two years. The programme has been slow to respond. The occurrence of cases in Cameroon up to July 2014 and the geographic spread to Equatorial Guinea show that SIA quality has been weak and that improvements are still needed; surveillance weaknesses also continue. Equatorial Guinea has also been slow to respond. Surveillance is completely inadequate; SIAs still leave many children unimmunized. Serious surveillance limitations in surrounding countries limit confidence of no further spread to date. In both Cameroon and Equatorial Guinea, enhanced Government ownership and leadership is essential. Syria and Iraq: From the beginning of the outbreak, the programme has considered this outbreak to be regional, and has treated it as such, including surveillance improvements and several rounds of SIAs in neighboring countries. The most recent case in Syria was in January 2014. Iraq has reported two cases so far, in February and April. Surveillance in both countries has been of variable quality. Significant instability is expected. Israel, the West Bank and Gaza: Since January 2014, bivalent oral poliovirus vaccine (bOPV) has been incorporated into the childhood immunization schedule in Israel. Environmental sampling from all sites has been negative for WPV1 since the week of March 30. No human cases of WPV1 were detected. Countries at Risk: Countries at highest risk for transmission, according to current risk assessments, are in West/Central Africa (particularly Central Africa), the Horn of Africa and the Middle East. The WHO African Regional Office has been following up with the highest risk countries in Central Africa to follow through on recommendations from a regional Technical Advisory Group meeting held in July. In addition, two rounds of synchronous SIAs will be held throughout West and Central Africa in September and November of this year except in the four West African countries affected by Ebola disease. Countries at risk in the Middle East have been undertaking risk mitigation activities since late 2013. Vaccine supply: Supply of both bOPV and tOPV has continued to be tight but well-managed through mid-2014 as no priority SIAs were deferred because of short supply. There is now sufficient buffer to meet planned increased demand in the second half of 2014. IPV supply has also been tight in 2014; nearly all available IPV was planned for introduction in routine immunization. The programme is finalizing plans for IPV use in SIAs in the three endemic countries. OPV supplies for 2015 are considered adequate, with a larger buffer available. Financing: Against the US$ 5.5 billion budget for 2013-2018, the best-case funding gap for the entire period is US$ 494 million. As of July 2014, the Initiative has cash on hand of US$ 908 million against the total budget of US$ 1.1 billion for 2014 Page ii GPEI Partner Status Report - 25 September 2014 Table of Contents EXECUTIVE SUMMARY .......................................................................................................... I! ACRONYMS AND ABBREVIATIONS .....................................................................................V! INTRODUCTION ................................................................................................................... 1! COMMUNICATION AND SOCIAL MOBILIZATION ............................................................... 2! ACCESSIBILITY AND SECURITY............................................................................................. 9! ENDEMIC COUNTRIES ........................................................................................................ 12! Afghanistan ............................................................................................................................................ 12! National polio overview .................................................................................................................. 12! Virology ............................................................................................................................................... 13! Poliovirus sanctuaries and risk areas .............................................................................................. 15! Communication and social mobilization ......................................................................................... 19! Programme information .................................................................................................................... 21! Performance indicators...................................................................................................................... 27! Synopsis ................................................................................................................................................ 29! Pakistan ................................................................................................................................................... 30! National polio overview.................................................................................................................... 30! Virology ............................................................................................................................................... 31! Poliovirus sanctuaries and risk areas .............................................................................................. 32! Communication and social mobilization ......................................................................................... 41! Programme information .................................................................................................................... 45! Performance indicators...................................................................................................................... 47! Synopsis ................................................................................................................................................ 49! Nigeria .................................................................................................................................................... 50! National polio overview.................................................................................................................... 50! Virology ............................................................................................................................................... 52! Poliovirus sanctuaries and risk areas .............................................................................................. 56! Communication and social mobilization ......................................................................................... 62! Programme information .................................................................................................................... 66! Performance indicators...................................................................................................................... 69! Synopsis ................................................................................................................................................ 71! NON-ENDEMIC COUNTRIES ............................................................................................... 72! Horn of Africa Outbreak ..................................................................................................................... 72! Somalia ................................................................................................................................................ 73! Ethiopia................................................................................................................................................. 74! Central Africa outbreak ....................................................................................................................... 76! Cameroon ............................................................................................................................................ 77! Equatorial Guinea .............................................................................................................................. 77! Middle East outbreak ........................................................................................................................... 78! Syria...................................................................................................................................................... 78! Iraq........................................................................................................................................................ 79! Page iii GPEI Partner Status Report - 25 September 2014 Middle East outbreak Response ...................................................................................................... 79! Other Countries/Areas with Detection of Active Poliovirus Transmission ................................... 82! Israel; the West Bank and Gaza .................................................................................................... 82! Countries at Risk .................................................................................................................................... 83! Countries with recent poliovirus transmission ................................................................................. 83! High-Risk Priority countries ............................................................................................................... 85! Mitigating activities ............................................................................................................................ 86! VACCINE SUPPLY AND MANAGEMENT ............................................................................ 87! STAFFING AND CAMPAIGNS IN 2014 ............................................................................... 91! FINANCING ........................................................................................................................ 94! Global Polio Eradication Initiative Financing Situation .................................................................. 94! Funding Gap ....................................................................................................................................... 94! Cash Gap............................................................................................................................................. 95! IMB Recommendations .......................................................................................................................... 95! Rotary Support ...................................................................................................................................... 99! ANNEX: LIST OF FIGURES ................................................................................................ 100! Page iv GPEI Partner Status Report - 25 September 2014 ACRONYMS AND ABBREVIATIONS AFP AGEs aVDPV bOPV C4D CAR CDC CMAM COMNet cVDPV DRC EOC FATA FLW GPEI HoA ICN IDPs IMB IPC IPV IVR KP acute flaccid paralysis anti-government elements ambiguous vaccine-derived poliovirus bivalent (types 1 and 3) oral poliovirus vaccine Communication for Development Central African Republic U.S. Centers for Disease Control and Prevention community-based management of acute malnutrition Community Mobilizer Network (Pakistan) circulating vaccine-derived poliovirus Democratic Republic of the Congo Emergency Operations Centre (Nigeria) Federally Administered Tribal Areas (Pakistan) frontline worker Global Polio Eradication Initiative Horn of Africa Immunization Communication Network (Afghanistan) internally displaced persons Independent Monitoring Board inter-personal communication inactivated poliovirus vaccine interactive voice response Khyber Pakhtunkhwa (Pakistan) LGA LPD LQAS mOPV NGO NID NPAFP OPV POB POLIS PTPs SIA SIAD SMS SNID STOP tOPV TP UC UN UNICEF UPEC VCM VDPV VTS WHO WPV local government area (Nigeria) low performing districts lot quality assurance sampling monovalent oral poliovirus vaccine non-governmental organization national immunization day non-polio acute flaccid paralysis oral poliovirus vaccine Polio Oversight Board polio information system permanent transit posts supplementary immunization activity short-interval additional dose short message service subnational immunization days Stop Transmission of Polio trivalent oral poliovirus vaccine transit point Union Council (Pakistan) United Nations United Nations Children's Fund Union Council Polio Eradication Committee (Pakistan) volunteer community mobilizer vaccine-derived poliovirus vaccination tracking system (Nigeria) World Health Organization wild poliovirus Page v GPEI Partner Status Report - 25 September 2014 GPEI Partner Status Report: 25 September 2014 INTRODUCTION This fifth GPEI Partner Report on progress towards polio eradication brings together input, analysis, and interpretation from the World Health Organization (WHO), Rotary International, the U.S. Centers for Disease Control and Prevention (CDC), and the United Nations Children’s Fund (UNICEF). The report examines both wild poliovirus (WPV) and circulating vaccine-derived poliovirus (cVDPV), with a focus on the key poliovirus 'sanctuaries' and risk areas in the three remaining polio-endemic countries (Afghanistan, Pakistan, and Nigeria) and indicators of progress towards the goals of the GPEI Polio Eradication and Endgame Strategic Plan 2013–2018. The report includes data about ongoing WPV outbreaks in the Horn of Africa (HoA), Central Africa and the Middle East; the detection of WPV in environmental samples; and an evaluation of countries at risk for importation. The WPV and cVDPV data represent cases with onset through 2 September as of 9 September 2014 (with noted exceptions) and with genomic sequence analysis through 20 August 2014. Analyses of WPV sanctuaries include data from acute flaccid paralysis (AFP) surveillance over the prior 12 months. For the analysis of standard surveillance and immunization indicators* by province/state for endemic countries, analyses include non-polio AFP (NPAFP) cases within the following onset intervals: 1) 16 February 2013 to15 August 2013, 2) 16 August 2013–15 February 2014, and 3) 16 February 2014–15 August 2014. For countries at risk, analysis includes AFP cases with onset of 16 August 2013–15 August 2014. Vaccine supply, human resource, financing and key programme information are reported as of 9 September 2014. Figure 1. WPV sanctuaries in polio-endemic countries, and countries and areas with wild poliovirus transmission within the prior 12 months, 19 September 2014 Source: GPEI The$boundaries$and$names$shown$and$designations$used$on$this$map$do$not$imply$the$expression$of$any$opinion$whatsoever$on$the$part$of$the$Global$Polio$ Eradication$Initiative$spearheading$partners$(WHO,$Rotary$International,$CDC$or$UNICEF)$concerning$the$legal$status$of$any$country,$territory,$city$or$area$ or$of$its$authorities,$or$concerning$the$delimitation$of$its$frontiers$or$boundaries.$Dotted$and$dashed$lines$on$maps$represent$approximate$border$lines$for$ which$there$may$not$yet$be$full$agreement.$$$ * Standard AFP surveillance performance indicators by province/state for this report include the following: 1) detection of at least two non-polio AFP (NPAFP) cases per 100,000 population aged <15 years annually and 2) adequate stool specimen collection from >80% of AFP cases (two specimens collected >24 hours apart within 14 days of paralysis onset, shipped on ice or in frozen packs to a WHO-accredited laboratory, and arriving in good condition). Standard immunization performance indicators by province/state for this report are: 1) <10% of children aged 6-35 months with NPAFP with an OPV dose recall history of 0 doses, and 2) >80% of children aged 6-35 months with NPAFP with an OPV dose recall history of 4 or more doses. Page 1 GPEI Partner Status Report - 25 September 2014 COMMUNICATION AND SOCIAL MOBILIZATION New insights in 2014 show that now, more than ever, communication with caregivers and communities can make or break the ability to reach every last child. Field data and recent polling by the Harvard School of Public Health show a clear picture of where success has taken place and the main social obstacles that must be overcome to finish the job in 2015. Acceptance of the oral Figure 2. Proportion of targeted children missed due to refusal, January 2013– poliovirus vaccine (OPV) August 2014 has reached the highest levels ever seen in Nigeria and Pakistan. As long as a vaccinator reaches the doorstep, 99% of parents in most parts of these two countries accept the vaccine for their children. When children are not vaccinated in any of the endemic countries, they are largely missed because of being outside the household (which may reflect covert noncompliance in part), poor inter-personal communication (IPC) skills at the doorstep or being inaccessible to vaccination teams Source: UNICEF because of insecurity. There is a proportion of children who are also missed due to teams not visiting planned households, which should also be reviewed and reduced. Whereas communication programmes in the past have focused almost exclusively on refusals and generating demand for vaccination, the role of communications has been changing rapidly in 2014 to address the critical remaining challenges in the programme: inaccessibility and insecurity, population movement, children out of the house, apathetic vaccinator practices and poor vaccination team performance. The rise in refusals in Khyber Pakhtunkhwa (KP) by nearly 80% between May and June, however, is a reminder that parents’ tolerance for repeated vaccinations is finite and cannot be taken for granted. Each of Nigeria’s six polio-affected families this year refused OPV for their child at least once before the onset of paralysis; four of the six families categorically refused OPV vaccination for their children and are zero-dose. Nearly 15% of Pakistan’s polio victims this year have come from refusal families—triple last year’s proportion. Page 2 GPEI Partner Status Report - 25 September 2014 We must continue to provide new and fresh ways to convince parents that the threat of polio remains serious, an increasingly difficult point to prove with so few visible reminders of risk. We must be equipped to offer more than just a message. Figure 3. Missed children in high-risk areas of endemic countries, October 2013– August 2014 Outbreaks pose complex challenges of their own, forcing the programme to fight polio on multiple fronts with limited resources and time, and in areas where mechanisms previously put into place to eradicate polio have long been deactivated. Fresh outbreaks have largely meant starting back up from zero in staffing, tools and emergency response procedures. Outbreaks also mean intensified communication challenges, including creating demand for the vaccine among a population that hasn’t seen polio in years or even decades, and where only a single case or a small number of cases may have emerged. Local solutions are needed for localized challenges, yet the toughest challenges persist across the endemic and outbreak countries alike. In its May 2014 report, the Independent Monitoring Board (IMB) identified three key areas for improvement in communication and social mobilization: 1) measuring and raising the standard of social mobilizers’ performance, 2) enhancing vaccinators’ IPC skills for difficult conversations, and 3) creating common ground on the value of social mobilization in addressing the programme’s greatest challenges. Renowned external expertise is now on board to support these and other efforts. More than 30 organizations with expertise ranging from polling and data management, training, innovation and advertising have been brought on as partners through long-term agreements that allow UNICEF and WHO to contract and implement quickly. Harvard and Johns Hopkins Universities, BBC Media Action and Seed Scientific are a few examples of global partnerships being harnessed to solve the most chronic and localized challenges identified below. Page 3 GPEI Partner Status Report - 25 September 2014 MEASURE AND RAISE THE STANDARD OF SOCIAL MOBILIZER’S PERFORMANCE The size and scale of social mobilization networks continue to rise in order to tackle the remaining challenges of the programme. More than 15,000 social mobilizers are now working and redeployed to the highest risk areas to maintain demand for OPV and ensure that all children are vaccinated, whether they are missed because of refusal or other reasons. Most social mobilizers are also promoting broader health activities in support of polio. This vital link to parents and communities—the very people who will determine the fate of eradication—provides an unprecedented opportunity to open doors for vaccination where it matters most. The skills, flexibility and accountability of this workforce in the face of ever-changing social and operational challenges will be critical to the GPEI’s success in the next— and hopefully last— low season. Figure 4. Number of social mobilization networks, January 2013–August 2014 Social mobilization networks have been rising consistently for the past two years to meet a growing need to build community support in the highest risk areas. Recruitment, deployment and training have taken place simultaneously in each country to ensure that people are in place quickly. More than 6,000 permanent mobilizers and supervisors were recruited in one year alone in Nigeria. Amidst an urgency to deploy these frontline workers, training suffered. Although training is provided across each network, there has so far been no standard package of development that each tier of mobilizers is expected to receive before deployment. Skills are currently imparted through on-the-job experience, supervisor support and training courses, delivered as they become available—with varying length and quality at field level. Few mechanisms are in place to evaluate whether the trainings have imparted the required skills to each mobilizer successfully, or to the network as a whole. To equalize skills across all layers of the networks, UNICEF has developed a learning framework that outlines the skills and curriculum required for each tier of social mobilizers—from community, sub-district, district and state/provincial level. Customized modules will be delivered to each tier depending on their core functions. A professional training company has been hired to adapt existing content into interactive, participatory adultlearning methodology that imparts skills and knowledge together. This package will be preceded by a basic IPC training for all frontline workers (see below) which should be ready for the field before the 2015 low season. Page 4 GPEI Partner Status Report - 25 September 2014 Short message service (SMS) and Interactive Voice Response (IVR) technology has been developed to monitor motivation and training delivery in critical areas. Short surveys delivered through mobile phones—and voiceautomated for illiterate workers—consists of three short questions asking whether a mobilizer has recently received payment, training and a recent visit from his or her supervisor. These data can be mapped in realtime and reviewed online globally—along with other campaign indicators—to better understand key drivers of performance. This technology is now being piloted and will be useful not only to make immediate corrections, but also to pinpoint where revised training and coaching is most critically needed. What distinguishes an exceptional mobilizer from a mediocre or non-performing mobilizer is a mix of knowledge, skills, profile, commitment and motivation. Ultimately, performance comes down to whether a frontline worker is able to gain the trust of the person on the other side of the door. We know this trust is hardest to build in Figure 5. areas that are already predisposed to conflict, insecurity and dysfunctional health systems. The way frontline workers are equipped to do their job must involve not only tools to build knowledge and skills, but also passion and motivation to overcome the many obstacles that remain in key sanctuaries and risk areas. For these reasons, a motivational Source: UNICEF system is embedded in the learning strategy that offers personal incentives to innovate, invest in personal development and share experience and lessons with fellow workers or staff. When the system is complete, mobilizers can aspire to be a ‘black belt’ in IPC, data collection, health or any other relevant topic and collect points, stars, belts or other symbols that visibly demonstrate their excellence. These visible ‘awards’ can offer prestige and credibility when workers meet a parent at a doorstep as well as serve towards advancement opportunities within a high performing network and hopefully beyond in local health systems. All of these variables will be monitored in each country and globally through a standard performance dashboard, shown in Figure 5. These data, along with other indicators monitoring the rest of the programme, will flow upwards from district level into a system that will house global performance data online across all countries. This database will enable information to flow more quickly down to the field for action, as well as upwards for strategic decision making at provincial, national and global levels. The new system will greatly Page 5 GPEI Partner Status Report - 25 September 2014 enhance clarity on performance. The key will be to incorporate these data into local and global GPEI oversight forums and use the information for rapid action on the ground, where it matters most. ENHANCE VACCINATOR’S IPC SKILLS FOR DIFFICULT CONVERSATIONS Polio eradication will be won or lost by frontline workers. A trusted vaccinator succeeds in getting parents to open their doors. A skilled vaccinator does not leave a household without finding and vaccinating every child in the house. A knowledgeable vaccinator can explain to confused parents why he/she must vaccinate their children today, even if they have already done so many times before. An exceptional vaccinator will communicate other health behaviors and be welcomed eagerly when he or she returns the next month. Trust in frontline workers—and in the polio programme more broadly—is unfortunately lowest in the areas it is needed the most: Borno and the Federally Administered Tribal Areas (FATA). This finding is confounded partially by the fact that fewer parents in these locations have recently seen a vaccinator compared with parents elsewhere in the country. Even among parents who have seen vaccinators, a favorable opinion of vaccinators is significantly lower than elsewhere in each country. The gender and demographic profile of frontline workers are closely associated with their ability to foster trust. According to recent polls, 32% percent of mothers and fathers in FATA said they prefer at least one of the vaccinators who arrive at their doorstep to be a woman. Only 8% in Borno, and less than 5% in the rest of Nigeria, want to see Figure 6. Poll Responses Regarding Trust in Vaccinators, Nigeria and Pakistan two men arrive at their doorstep. Nigeria has responded to these community preferences in the profile of both social mobilizers and vaccinators. Although the GPEI in Pakistan has generally been able to ensure that more than 80% of vaccination teams include at least one woman, success in recruiting female social mobilizers has not been comparable. The Community Mobilizer Network (COMNet) has maintained their female proportion of mobilizers around 20% for more than one year. This raises questions about the COMNet recruitment strategy as well as the coordination and sharing of lessons learned between vaccinator and mobilizer selection—an area that requires further integration in all countries. Page 6 GPEI Partner Status Report - 25 September 2014 In the southern region of Afghanistan, the opposite trend can be seen, with a slight increase in female social mobilizers over the past few months, but a general decrease in female vaccinators (except for a ‘one-off’ surge in March). Female mobilizers and vaccinators do exist in urban cities such as Jalalabad; in fact, they are the majority there. The reported 0% in Figure 7 for Eastern Afghanistan reflects that data are not recorded or monitored by the Afghanistan programme. This will need to be revised as the Immunization Communication Network (ICN) continues to expand. Figure 7. An IPC module has already been developed by UNICEF to introduce inactivated poliovirus vaccine (IPV) into routine immunization, and is available for use in country. A professional training company has been hired by UNICEF to adapt the existing IPC module in the WHO-led vaccinator training to be more interactive and skillbuilding. Given the scale and impact that a more skilled frontline workforce can have, the module for IPC training of vaccinators is prioritized for roll out by November 2014, followed by the social mobilizer training mentioned above. A growing body of evidence suggests that mobile phones, SMS, IVR and Android applications can also help build the capacity of community health workers. One example is BBC Media Action Trust’s Mobile Academy for community health workers in India, which delivers voice training and interactive quizzes via mobile phones. UNICEF is adapting these lessons to strengthen interpersonal training for frontline staff. Supplementary educational applications have been developed that reinforce IPC skills and key health messages through SMS and IVR. This “mHero” application—part of a customized social media package designed exclusively for polio training—tests new trainees on key knowledge learned after training courses, and is followed up later with behavioral questions once workers are in the field. This approach will complement UNICEF’s face-to-face training package, and has already been added to a new integrated health training that has been piloted with frontline staff in Katsina and Kaduna states in Nigeria. To see an example of the initial mHero Knowledge and Training application, click this link. ∗ An advertising agency has also been hired to translate polling data into easy-to-remember messages that can be delivered more innovatively by frontline workers. By the end of the year, informational videos can be transmitted and broadcast to frontline workers via Multimedia Message Service and Bluetooth to help aid their difficult conversations with parents. Frontline workers can use these videos for their own learning as well as to interact more systematically with parents and members of the community. ∗ !https://www.dropbox.com/s/7ps1ft9gw31j2z9/Polio%20Knowledge%20Training%20Application%20Schematic.pdf?dl=0!! Page 7 GPEI Partner Status Report - 25 September 2014 CREATE COMMON GROUND ON THE VALUE OF SOCIAL MOBILIZATION IN ADDRESSING THE PROGRAMME’S GREATEST REMAINING CHALLENGES The IMB has challenged the GPEI to have more honest discussions about the role of social mobilization in addressing the programme’s remaining challenges. Several face-to-face discussions have taken place on this issue since the last report: 1) in June at the face-to-face Polio Partners Group and Polio Oversight Board (POB) meetings on the need to better integrate operations and communications in global presentations and during programme implementation, particularly for access; 2) with the Bill and Melinda Gates Foundation and CDC at partner review meetings on the future direction and relevance of social mobilization networks in the highest risk areas; and 3) with WHO at the margins of the Global Polio Management Team on defining the role of communications—external communications and Communications For Development (C4D)—to facilitate access. The latter was among the first formal meetings to bring together colleagues from access, operations, communications and both of these complementary arms of communication (external and frontline). It was a positive progression in integrating not only operations and communications, but also integrating these two parts of the communications field that rarely intersect programmatically, but should as the enabling environment for the programme moves increasingly more fluidly between local and global spheres. These meetings focused on how communications should play a role rather than if communications should play a role, which is a positive indicator that the partnership sees the value of communications. What remains an underlying challenge is how to move these discussions from positive views to positive actions. The C4D Specialist in WHO’s Country Support Team—as well as WHO’s own C4D Specialist—have been bridges built between intentions, plans and implementation, though both organizations require a more fundamental culture shift to ensure that these two parts of the programme work together systematically. Since the last report, social data have been incorporated as a standing set of slides in the monthly InterAgency Country Support Group. The role of community engagement and demand has formally been incorporated within the strategic access framework of the GPEI and endorsed by the POB. A GPEI working group has been working collaboratively on analyzing and rehabilitating, if required, the reputation of OPV on the internet, particularly within influential online and social media platforms that have in the past maligned the reputation of OPV. Agreement has been established to ensure that UNICEF’s PolioInfo and WHO’s Polio Information System (POLIS) global database can exchange data and integrate seamlessly on a common website once they are both built. Despite the moves to revise modules, agreed-upon timelines have not yet materialized on operationalizing the updated vaccinator training. CDC continues to be an integral partner to identify, train and deploy Stop Transmission of Polio (STOP) volunteers where critical needs exist in the programme, and this support has extended to Ebola until July. CDC has further operationalized its support by facilitating a new partnership with Voice of America Pashto, which will significantly enhance the ability to reach Pashtun communities with more creative content. Rotary continues to be instrumental in promoting and facilitating health camps, particularly in Pakistan, as well as rehabilitation centers for polio-affected children. ROTARY’S EFFORTS TO RAISE POLIO AWARENESS Update on communications strategy Rotary continues integrated communications for polio: traditional media relations, expanded digital (including social) media efforts, celebrity engagement (more than 100 celebrities worldwide at all levels), and special events—currently focused on World Polio Day (24 October) as keystone for many events. Page 8 GPEI Partner Status Report - 25 September 2014 Rotary’s Online Museum Rotary communications staff are working on a digital storytelling platform to expand on the efforts already underway at www.endpolio.org/stories to gather stories of those whose lives have been affected by the fight to end polio, including volunteers, health workers, Rotarians, polio survivors, and other supporters. The final product will be an online “museum” of sorts telling the story of the global engagement around the issue. World Polio Day This year, Rotary is hosting its second annual World Polio Day Livestream event, featuring speakers including: Minda Dentler, an inspiring polio survivor triathlete; a video message and song from Rotary polio ambassador Ziggy Marley; TIME Magazine science/technology editor Jeffrey Kluger; and—closing out the evening—a special concert from a rising pop star, who is one of Rotary’s newest ambassadors for polio eradication. In addition to these English-language events, the Rotary International communications team will be conducting media outreach in target countries globally to raise awareness and encourage people to donate and share their stories. Rotary International will also support other World Polio Day events that same week in: • Atlanta, GA at the U.S CDC on 21 October – CDC Director Dr. Tom Friedan and Rotary International President Gary Huang will be among the participants • Strasbourg, France: 21October at the European Parliament • Pakistan, where monuments will be illuminated with the “End Polio Now” message ACCESSIBILITY AND SECURITY The extent to which security continues to influence the ability of the GPEI to operate and access all children continues and, in some cases, has deteriorated considerably. The markedly different contexts of Nigeria and Pakistan are changing and are not likely to improve in the immediate- to medium-term. Similarly, the security situation in outbreak countries, particularly Iraq and Syria, has further worsened, resulting in both countries being considered as “L3 emergencies” within the United Nations (UN), the classification for the most severe, large-scale humanitarian crises. The added complication of the current Ebola outbreak has the possibility of adding another level of disruption to GPEI activities in West Africa. A number of significant events have made it difficult to conduct GPEI activities and access to key geographies has decreased. While the election period in Afghanistan did not have the level of violence expected, the south and east of the country witnessed increased population movements due to the military operations in Pakistan. The more significant issue was in Helmand Province where the area was fully inaccessible to GPEI activities from March to July. Although a large degree of effort at various levels occurred, not least from both UNICEF and WHO country offices, access has only just been granted with campaigns held in August. Pakistan has also witnessed a high degree of turmoil since June when the military launched an operation into North Waziristan in attempt to deal with anti-government elements. This operation has led to almost 1 million people migrating into the surrounding areas, including Afghanistan. This has provided the GPEI with a unique opportunity to reach children previously unvaccinated. However, this movement has resulted in spread of the virus to host communites and sporadically elsewhere. The security situation in Nigeria, especially in the Northeast, has continued to deteriorate. The Government reports that inaccessibility due to insecurity declined from 100% in March 2013 to approximately 23% currently. Despite an improvement, the situation has worsened from the 14-16% low seen in March 2014. This situation is predominantly due to the insurgency and subsequent military action in the Northeast. Communal violence is also present, especially in the Middle Belt. Insurgent activities have resulted in the Government’s Page 9 GPEI Partner Status Report - 25 September 2014 State of Emergency remaining in place since May 2013. The insurgency has regional ramifications on security and population movement, particularly to those countries directly neighbouring Nigeria. In early August, the Office for the Coordination of Humanitarian Affairs reported that the insurgency in the Northeast of the country had forced nearly 650,000 people from their homes, an increase of nearly 200,000 since May. The GPEI’s ability to fully monitor campaigns in the key area of Borno has been further hampered by the current ban by aviation authorities on commercial flights and by the lack of transport alternatives. While the security situation in specific areas of endemic and outbreak countries is challenging, the GPEI has continued to respond. Earlier this year, the GPEI agreed and the IMB reemphasized that it is important for GPEI partners to share common analyses and approaches to access and security, and to ensure sharing of all relevant information and insights as a basis for the development of common implementation strategies. Interagency coordination and accountability mechanisms will be critical to the success of all access strategies. To that end, UNICEF and WHO have sought to improve collaboration with partners to seek multifaceted measures to reach every child. The most significant strategic development has been the agreed-upon coordinated approach that includes initial analysis, methods to facilitate access, and the development of appropriate delivery approaches. There is agreement that community acceptance, trust and demand generation are the foundation for ensuring security for polio vaccination efforts and health workers. Once the political and conflict-related challenges that underpin the vaccination bans or attacks on polio vaccination efforts are being addressed, it is then essential to understand and respond to the perspectives of parents and communities on reaching all children. This overall strategy provides breadth to the way in which delivery strategies are implemented and three main approaches are involved. The first approach is analyzing the situation through data and information from various components—political, social, security/conflict, epidemiological and polio campaign data. Collecting and analyzing these diverse strands of information allows the GPEI, for example, to understand the root causes for opposition to polio vaccination efforts and concerns of the beneficiary communities, and help map the key influencers and processes to reach them. The second approach involves the development of appropriate, area-specific access tactics based on the analysis that has been conducted, and the available channels to discuss and develop these access tactics. The POB endorsed four programmatic tactics. They include: • Negotiated Access. This is the primary tactic and includes the engagement of religious and community leaders, tribal elders and tribal structures; engagement of national and provincial governments and their agencies, including military and law enforcement authorities; engagement of third party influencers, both local and international; and indirect engagement of non-state armed groups to allow the conduct of required number of SIAs to help stop WPV transmission. • Opportunistic Vaccination Strategies. Smaller scale and low-profile activities to reach and vaccinate children. These are important initiatives, but not likely sufficient to stop poliovirus transmission. They include: permanent transit point vaccinations; ramping up routine Expanded Programme on Immunizations (EPI); self-vaccination initiatives; immunization by local non-governmental organizations (NGOs) and humanitarian organizations; and initiatives for nomadic and other mobile or displaced populations. Provision of broader health interventions creates opportunities for vaccination through increasing demand and ensuring the security of workers. • Protected Vaccination Campaigns. This is the engagement of military and local law enforcement to provide protection to health workers and support the polio eradication activities. The GPEI understands that military or local law enforcement forces will not be directly involved in administering vaccines, and that the use of military will be time-limited and as a last resort. In areas completely under the control of Page 10 GPEI Partner Status Report - 25 September 2014 • military authorities, no health or humanitarian activities are possible without the support and approval of military leadership. Engaging communities. Ensuring communities want and trust vaccination efforts (IPV and OPV) will maximize the potential to reach all children once access is achieved. This is achieved through seeding demand for immunization and health services though radio, TV and IPC where possible, and the development and implementation of targeted social mobilization and C4D initiatives. The third approach involves the full exploitation and integration of social mobilization and C4D initiatives of this last programmatic tactic into the programme planning and delivery strategies to ensure the greatest levels of access to children and communities. Broadly, these include the following: • Community Acceptance. To create the conditions of community trust and acceptance that will enhance security for health workers, and develop multiple local channels to secure and sustain access to the last remaining children. This tactic targets those who can influence change at the community level to accept polio vaccination efforts. • Demand-generation. To help address the key concerns of the parents, promote the role of vaccinators and local health workers, and create demand for immunization services and health interventions. This tactic targets families, parents, vaccinators and health workers. • Improved Service Delivery. To improve the programme’s ability to understand the various social factors and help deliver quality services that respond to community demands. This tactic targets programme staff, third party organizations, local governments and can ensure that any opportunistic vaccination efforts are of the highest quality and help reach the greatest numbers of children from previously inaccessible areas. Looking forward to the remainder of the year and beyond into 2015, further strategic shifts continue to be developed: • Operationalizing a fully integrated approach to engaging communities at all levels, address community demands and secure access, including convergence strategies • Moving from a Joint Security Approach to a Joint Access Approach to capture the multifaceted strategy to reach every last child • Providing proactive analytical and wider research capability to support programme delivery. Ensuring that data are available to all decision makers and used for action • Focusing on addressing specific inaccessibility issues—scenario-based approach/emerging threats/ political instability/population movements/Western & Central Africa/HoA/Middle East/Pakistan/ Afghanistan Page 11 GPEI Partner Status Report - 25 September 2014 ENDEMIC COUNTRIES AFGHANISTAN Figure 8. WPV and cVDPV cases, Afghanistan, 2013 and 2014 to date* NATIONAL POLIO OVERVIEW The number of WPV1 cases in Afghanistan decreased from 37 in 2012 to 14 in 2013; ten cases have been reported to date in 2014 (as of September 23, 2014) compared with four cases during the same period in 2013, the majority of which have occurred in the Eastern Region. Two cases occurred in the Southern and, South Eastern regions, and one case occurred in the Western region. During the last 12 months, most reported cases were importations from Pakistan. SIAs have primarily used bivalent (types 1 and 3) oral poliovirus vaccine (bOPV) Source: WHO during the reporting period. Two national immunization days (NIDs) in 2014 used trivalent oral poliovirus vaccine (tOPV) and one short-interval additional dose (SIAD) SIA used monovalent OPV1 (mOPV1). Seven SIAD SIAs and two subnational immunization days (SNIDs) have been Source: WHO *Data as of 9 September 2014 conducted to date in 2014; most included the low performing districts (LPDs) of the Southern Region as well as several rounds of case response vaccinations. After a hiatus in access since March 2014, access to Helmand was granted in late August and one SIA was conducted during the last week of August to be followed by three SIAs in the entire province. Lot quality assurance sampling (LQAS) surveys indicated improvements in campaign quality during 2014 compared with 2013. “Permanent polio teams” that provide OPV to children on a continual basis started to use tOPV in March 2013. Currently, 65 permanent polio teams are working in 11 LPDs in the Southern Region. IPV is being introduced in LPDs in the October 2014 NID using fixed posts. A plan is in place to introduce IPV into the routine immunization schedule in the entire country in mid- to late-2015. Remaining challenges include access in Kunar in the East (one previously inaccessible district had breakthrough negotiations and full access beginning in June). In addition, the exodus of internally displaced persons (IDPs) from Waziristan during June–July 2014 posed a risk for WPV importations into Afghanistan. In response, nine mobile vaccination teams were established to deliver routine immunizations to displaced populations. More than 40,000 children were vaccinated with tOPV when entering Afghanistan; most had never previously received OPV (i.e., most were zero-dose). The number of border crossing points was increased from four to Page 12 GPEI Partner Status Report - 25 September 2014 eight and the target age group for polio vaccination at border crossing points and IDP camps was increased to <10 years. In addition, three rounds of SIAs have been conducted between June and August 2014 in the Southeast Region using bOPV. VIROLOGY WPV1 from five genetic clusters (R4A1, R4B1, R4B2, R4B5, and R4B6) were isolated from 12 August 2013 through 11 August 2014. Two viruses were detected in Southern Afghanistan (R4B1 clusters), representing local transmission. The other WPV cases are related to WPV importation from Pakistan. Six (35%) of the17 WPV1 in Afghanistan had less-than-expected genetic linkage to other viruses from Afghanistan or Pakistan, indicating surveillance gaps in either Afghanistan or Pakistan. These orphan viruses were detected in four separate locations, including Kabul. Two orphan viruses from cases in the South Region were indigenous viruses that had been circulating undetected for >20 months, indicating both ongoing endemic transmission and surveillance gaps. Four orphan viruses from cases were imported from Pakistan. Environmental surveillance in Afghanistan began in September 2013. Currently, Afghanistan has nine environmental surveillance sites; two each in Kandahar, Helmand, and Nangarhar Provinces which were initiated in late 2013/early 2014 and three sites in Kabul were added in June 2014. WPV1 was detected for the first time in specimens taken in Kandahar and Nangarhar Provinces in July 2014. To date, no sites had VDPV detected. No cVDPVs were detected during April 2013 to March 2014. However, isolation of VDPV from an immunodeficient patient during November 2013 needs close monitoring and follow-up. The last known emergence of cVDPV2 in Afghanistan was in early 2013 with three cases detected. 1. Seventeen WPV1 cases were detected in the past 12 months; all were in four provinces in the east bordering Pakistan, except three that mapped in the Southern and Western Regions. 2. Although the numbers of cases have declined, the proportion of orphan viruses has increased, involving separate geographic locations. 3. No cVDPVs were detected during this time period. Page 13 GPEI Partner Status Report - 25 September 2014 Figure 9. Wild poliovirus type 1 (WPV1) by genetic cluster and circulating vaccine-derived poliovirus type 2 (cVDPV2) by emergence, Afghanistan & Pakistan, 2013 and 2014 to date* 2013 2014 WPV1 cVDPV2 Source: CDC * Data as of 20 August 2014 Page 14 GPEI Partner Status Report - 25 September 2014 POLIOVIRUS SANCTUARIES AND RISK AREAS SOUTHERN SANCTUARY Figure 10. WPV and cVDPV cases, Southern Sanctuary, 3 September 2013 to 2 September 2014* Afghanistan has one WPV sanctuary, Helmand and Kandahar Provinces, which historically were the main reservoir of endemic WPV transmission. Within that area, the country has 11 LPDs because of inaccessibility, confirmation of endemic circulation in the previous two years, weak or declining SIA quality, low level of awareness of SIAs, and a disproportionally high percentage of young children with NPAFP who have never received OPV. In May 2014, the number of LPDs for this sanctuary increased from 11 to 16. Source: WHO *Data as of 9 September 2014 Notes regarding Afghanistan’s lot quality assurance sampling (LQAS) survey results (see next page): Decision rules of 0–3, 4–8, 9–19 and 20–60 for sample sizes of 60 provide a reasonable assessment of SIA quality at 90% (High Pass), 80% (Pass) and 60% (Low) thresholds (or Fail if below) for programmatic purposes under the assumption of moderate variability in cluster-level results. Page 15 GPEI Partner Status Report - 25 September 2014 Figure 11. WPV and cVDPV cases by week of onset, Southern Sanctuary (Helmand and Kandahar Provinces), Afghanistan, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Figure 12. LQAS survey results by SIA, Southern Sanctuary, Afghanistan, Sept 2013 to Aug 2014 Note: The “n=” numbers shown above each month represent the number of districts for which data are available. Data from October and November 2013 include all available data from Kandahar and Helmand. LQAS data from February 2014 were only available from the 11 low performing districts. LQAS data from March, June, and August 2014 include all available data from Kandahar; LQAS was not conducted in Helmand. Figure 13. Proportion of NPAFP cases 6-35 months, by OPV status, Southern Sanctuary, Afghanistan** Source: WHO **Data as of 2 September, 2014 Page 16 GPEI Partner Status Report - 25 September 2014 EASTERN RISK AREA Figure 14. WPV and cVDPV cases, Eastern Risk Area, 3 September 2013 to 2 September 2014* WPV from Pakistan has been imported into the east of Afghanistan during 2012–2014. In turn, the six provinces Nangarhar, Kunar, Laghman, Nuristan, Khost, and Paktya have been designated as the “Eastern Risk Area.” Six districts in the area were designated as LPDs in 2014. Source: WHO *Data as of 9 September 2014 Page 17 GPEI Partner Status Report - 25 September 2014 Figure 15. WPV and cVDPV cases by week of onset in the Eastern Risk Area (Kunar, Nangarhar, Laghman, Nuristan, Khost, and Paktya Provinces), Afghanistan, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Figure 16. LQAS survey results by SIA in the Eastern Risk Area Afghanistan, Sept 2013 to Aug 2014 Note: The “n=” numbers shown above each bar month represent the number of districts for which data are available. Figure 17. Proportion of NPAFP cases 6-35 months, by OPV status, Eastern Risk Area, Afghanistan** Source: WHO **Data as of 2 September 2014 Page 18 GPEI Partner Status Report - 25 September 2014 COMMUNICATION AND SOCIAL MOBILIZATION Figure 18. PERFORMANCE In Afghanistan, parents rarely turn a vaccinator away because they don’t believe in OPV or think it’s unsafe. They turn vaccinators away because they remain unconvinced that polio is a threat serious enough to warrant waking a sleeping child, or to bring a newborn out of the house before social Source: UNICEF norms permit. Doubt remains among parents that OPV is safe enough to risk giving it to a sick child. Newborn, sick and sleeping concerns may not represent overt objections to the programme or vaccine but it does highlight gaps in training of frontline workers, the inability of social mobilizers to assuage parental concerns and the lack of a comprehensive revisit strategy. In the 11 LPDs of Southern Afghanistan—where immunity gaps are second only to Borno and FATA—refusal rates have remained at nearly the same “high risk” classification for the past two years. Despite being low in absolute numbers, the lack of progress on refusal rates in Southern LPDs, and the inability to identify clustered refusals pose a significant threat to interrupting transmission. But the absent children who are left unvaccinated after campaigns are even more critical. More than 5% of all children in the South are missed because they are out of the house and unreached with follow-up, 2% in the East. Significant shifts in the operational strategy, such as compilation of tally sheet results and a thorough revisit strategy to find and vaccinate missed children after campaigns, is central to reaching every child in Afghanistan. Though an intensely complex working environment, underlying reasons for the alarmingly high rates of missed children and poor performance in these districts are not clear. Tracking and monitoring need to be systematically introduced and followed up with localized revisit strategies; these strategies have been successfully applied in several areas of Southern Afghanistan. In Aug 2013 12,574 of the 37,307 children who were recorded as “not available” remained unvaccinated, whereas in Aug 2014, with a revisit protocol, 35,350 children out of 41,002 who were “not available” were vaccinated on the fourth day revisit. These basic protocols can significantly improve the quality. In Afghanistan, social mobilizers are not permanent, and recruitment for at least part of the network is done afresh each month. This constant cycle of recruitment, training and campaign activities puts a burden on the management level of the programme and the level of training that can be provided in just one day is very basic. It is unclear whether ICN—and in fact all frontline workers—have the appropriate IPC skills to make an impact on newborn, sick and sleeping children, and whether skills exist across the spectrum of frontline workers Page 19 GPEI Partner Status Report - 25 September 2014 to address the reasons for missed children. This issue should be considered as matter of priority for the six districts in the South with consistently low coverage. Figure 19. Proportion of missed children and missed because of refusal among targeted children in selected LPDs in Southern Afghanistan, October 2013 to August 2014, Source: UNICEF COMMUNICATION FOR ACTION In some of the most complex and insecure areas, ICN’s main function is to facilitate access on large and small scales. Of the ICN’s 11 Provincial Communication Officers, two were recruited mainly to support access (North Helmand and Farah) during all campaigns. Of the current 53 LPDs in the East and South (19 newly designated since May 2014; previously 32 LPDs, 21 in the East and 11 in the South), nine District Communication Officers (seven in the 10 LPDs in Kunar; and two in the nine LPDs considered top priority in Kandahar province) were recruited for their community standing and ability to reach and negotiate access with among anti-government elements (AGEs). As a result, the conventional strategy of pre-campaign houseto-house mobilization, vaccination and finger markings do not take place in these areas. Instead, the non-state entities agree to allow children and caregivers to assemble in designated health facilities, mosques and other central locations so the children may be vaccinated. These specialized arrangements are facilitated by the ICN in these districts where children might otherwise be left unreached. The recent access negotiations in Helmand Province and in Watapur District (Kunar Province) were brokered at the community level by ICN staff. ICN helped identify many local objections, in particular to the profile of frontline staff by speaking with local commanders and community leaders and ensuring their input in selecting vaccinators and social mobilizers. In the Kajaki area of Helmand, this meant changing 13 of 17 cluster Page 20 GPEI Partner Status Report - 25 September 2014 supervisors and in Helmand’s Musa Qala district, frontline workers from outside the community were replaced with local workers. This quiet and constant negotiation on the ground, along with high-level discussions with senior leadership, meant access to children in Helmand in August for the first time since March of this year, and sustained access since May to children in Watapur District, Kunar Province, inaccessible for four years. While a non-permanent workforce provides unique challenges, the relative flexibility of the ICN conversely allows it to respond quickly to changing circumstances on the ground. With no campaigns in Helmand from March to August, the ICN workforce was reduced. Once access was regained, more than 1,300 social mobilizers were reactivated to respond and support the campaign. Seeing increased missed children in the East Region, Batikot and Shinwar LPDs, the ICN deployed 150 new social mobilizers to these new priority districts. To help support the IDP influx from North Waziristan, ICN added more social mobilisers in Khost. RECRUITING WOMEN Recruitment of female social mobilizers, though improving, is a major challenge. In Kandahar, involvement of female social mobilizers created suspicion among male community leaders who suspected access to households for spying. It reportedly also forced changes in vaccinator profile as it is considered inappropriate for unmarried men and women to be in public together, leaving female frontline workers clustering together in groups for safety and community acceptance, but in the process reducing efficiency. Though it is critical that female social mobilizers be available to facilitate access to households and female caregivers, their profile, selection and acceptance by the community is crucial. The Afghanistan team is in the process of identifying a realistic minimum standard for the gender mix of social mobilizers while simultaneously identifying other opportunities to engage mothers in culturally acceptable ways, such as through shrine activities, mothers’ meetings, and hospitals. PROGRAMME INFORMATION ACCESSIBILITY AND SECURITY During February through September, the security environment in Afghanistan has been dominated by a few major factors—presidential elections, seasonal fighting trends, Ramadan, internal leadership struggle among AGEs, and Pakistan military operations in North Waziristan. The South and Eastern Regions, the areas in which the virus predominantly circulates, continue to produce the highest number of security incidents per month that, to some degree, has an impact on the ability to implement the programme. Traditionally, security incidents in Afghanistan rise steadily month-on-month until August where they then begin to reduce as winter approaches and reach a low in February. No significant deviation has occurred from this pattern so far this year, although a reduction of incidents was seen in July because of Ramadan. A continuation of this normal trend is anticipated for the remainder of the year; however, security incidents will likely be higher than previous years because of the contested outcome of the elections and planned withdrawal of deployed international military by December 2014. The prolonged presidential election period has caused uncertainty and high level of security incidents. Results of the process should be known in mid- to late-September, but the chances of instability and ethnicity-based violence is expected to increase given lack of support for the UN audit process among one of the candidates and by both their powerful backers. The parliamentary elections will begin almost immediately after this, ensuring that the security environment continues to be influenced by the political process. Bi-lateral security agreements by NATO members have not been signed owing to the lack of a clear winner in the presidential elections, thereby creating greater security vacuum that is being exploited by the AGEs. Page 21 GPEI Partner Status Report - 25 September 2014 The Pakistan military operations along border areas with Afghanistan have also caused security challenges within the country. There have been numerous reports of fighters moving into South East Afghanistan and beyond, and it is assessed that many of these fighters were able to move relatively freely among displaced persons, before heading deeper into other regions of Afghanistan. In some areas in the Eastern region of Afghanistan, it is assessed that these factions have affected the leadership of local AGEs and may result in a more hardline approach to humanitarian activities, including polio programme activities. SECURITY INCIDENTS AGAINST THE POLIO PROGRAMME Eight incidents and four fatalities occurred directly involving the Afghanistan polio programme during February through September 2014. The majority have occurred in the Southern Region, traditionally the most volatile Region in country with abduction of staff for short periods being the most common type of incident. Analysis indicates that this is generally criminally motivated rather than a concerted effort to prevent the polio programme from operating. There is no evidence of a concerted effort to prevent polio vaccination through violence in Afghanistan. Figure 20. Source: UNICEF Page 22 GPEI Partner Status Report - 25 September 2014 INACCESSIBILITY Since August, access has improved substantially in Afghanistan with inaccessibility registering 0.55% of the total target population. Limited campaigns were conducted during July because of Ramadan, with fewer attempts to access and resulting in artificially low inaccessibility figures. Results mentioned below refer to inaccessibility involving vaccination teams, not monitoring teams. Inaccessible districts continue to match areas where security incidents are consistently high, and where the UN Security Levels System deems as high or extreme threat. Figure 21. Proportion of Missed Children due to Inaccessibility among Targeted Children <5 years of age, by Region, Afghanistan, October 2013 to August 2014 Source: UNICEF Southern Region has seen two areas that demonstrated significant improvements in inaccessibility. Inaccessibility for the Region is assessed to have returned to pre-March 2014 levels of approximately 1% of the 1.55 million children under 5 years of age. Notable successes have occurred in Afghanistan to reduce inaccessibility: • For most of the reporting period, Helmand Province was classified as 100% inaccessible with approximately 700,000 children in the target population. After dialogue at several levels, and subsequent changes in some personnel, access was gained in August. A single cluster in Sangin District retains inaccessibility because of ongoing fighting. • Kandahar Province, Southern Region has demonstrated pockets of inaccessibility, which was particularly poor in Shawalikot and Mianashin Districts. Local dialogue held by access negotiators, District Communication Officers, and District Polio Officers led to improved access for vaccination teams. Page 23 GPEI Partner Status Report - 25 September 2014 • • • Issues remain in Ghorak District, Kandahar Province, where significant fighting is taking place. Afghan National Security Forces control the District Admin Centre (DAC), and AGEs control the surrounding areas. Inaccessibility now currently sits at 14% of the 8,811 target population and the focus now is for dialogue in Kandahar Province to address this area. East Region has elicited a sustained level of inaccessibility of approximately 2% of the 936,000 target population. Watapur District, Kunar Province is a success story in the area having been inaccessible for more than four years. Progressive local level dialogue with key actors, led by District Communication Officers, and District Polio Officers resulted in access being granted for vaccinators in May 2014. This access has continued to be granted. The effect of displaced persons moving from Pakistan into South East Region of Afghanistan (Khost Province) has caused no substantial access problems. An isolated case of 26,000 children being missed was rectified within days through local level dialogue. The movement of these people from North Waziristan can be viewed as an opportunity to vaccinate those previously missed. Figure 22. Inaccessible areas, 2014 WPV1 cases, and the estimated proportion of children affected during the August 2014 SIA - Eastern Risk Area and Southern Sanctuary, Afghanistan Source: WHO *Data as of 9 September 2014 Page 24 GPEI Partner Status Report - 25 September 2014 OWNERSHIP National National EPI Committee Weekly Meetings National held with minutes available National EPI Dialogue CommitteeGroup Weekly Meetings Polio Policy Quarterly held with minutes available Meetings held with minutes available Polio PolicyQuarterly DialogueMeeting Group Quarterly President's with Meetings held Governors heldwith minutes available President's Quarterly Meeting with Inter-Ministerial Task Force Quarterly Governorsheld held Meetings Inter-Ministerial Task Force Quarterly Meetings held Regional Regional/Provincial EPI Management Teams RegionalMeetings held Monthly EPIminutes Management *Regional/Provincial Held fortnightly ** No availableTeams Monthly Meetings held Q4 '13 Q1 '14 Q2 '14 Q3 '14 Yes Q4 '13 Yes* Q1 '14 Yes* Q2 '14 Yes* Q3 '14 Yes Yes Yes* Yes Yes* Yes Yes* Yes Yes No Yes No Yes No Yes No No No No Yes No Yes No Yes No Q4 '13 Yes Q1 '14 Yes Q2 '14 Yes Q3 '14 Yes Q4 '13 Yes Q1 '14 Yes Q2 '14 Yes Q3 '14 Yes Yes Yes Yes * Held fortnightly ** No minutes available Percent of Southern Region low performing districts meeting preparedness indicators OWNERSHIP (CONTINUED) Indicator: District Coordination Committee Meetings Held (yes / no) Percent of Southern Region low performing districts meeting preparedness indicators Low Performing Region Districts Meetings Dec Held '13 (yes Jan '14 Feb '14 Mar '14 Indicator: DistrictSouthern Coordination Committee / no) Apr '14 May '14 Jun '14 Jul '14 Aug '14 8 Dec '13 100 8 8 Jan '14 100 8 8 Feb '14 100 8 5 Mar '14 60 5 5 Apr '14 80 5 5 May '14 80 5 5 Jun '14 80 5 Jul '14 5 Aug '14 80 5 Preparedness indicator met Shahwalikot 100 Yes 100 Yes 100 Yes 60 Yes 80 Yes 80 Yes 80 Yes 80 Yes Maiwand Shahwalikot Panjwai Maiwand Boldak Panjwai Bust (Lashkar Gah) Boldak Nahesaraj Bust (Lashkar Gah) Nadali Nahesaraj Sangin Nadali Kandahar Sangin Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No* Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes Yes No No Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes No Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No campaign No data Yes Yes Districts Participating Low Performing Southern Region Districts Preparedness indicator met Districts Participating Kandahar Abbreviations: EPI=Expanded Program No* Yes on Immunization Yes Yes Yes Source: Afghanistan Campaign Dashboard, WHO-Afghanistan No campaign No data Abbreviations: EPI=Expanded Program on Immunization * Meeting in Kandahar is not at district level but is the Provincial Coordination Committee Meeting which is held regularly before each campaign. Source: Afghanistan Campaign Dashboard, WHO-Afghanistan * Meeting in Kandahar is not at district level but is the Provincial Coordination Committee Meeting which is held regularly before each campaign. Note: Results for 9 of the 11 Low Performing Districts were available at the time of this report. The 2 districts missing are Arghandab and Khakrez. HUMAN RESOURCES Location$ Number$of$ Number$(%)$of$ Number$(%)$of$ Salary$per$ vaccination$ vaccination$teams$with$ vaccination$teams$with$a$ vaccinator$/$day teams a$female$member local$member PEI$ Coordinator Number$of$current$GPEI$staff Provincial$Polio$ District$$$$$$$$$$ Total Officer Polio$Officer Kandahar$and$ 3,254 164$(5%) 2,992$(92%) $5.00 3 20 20 43 Helmand Nangarhar,$Kunar,$ Laghman$and$ 2,846 140$(5%) 2,789$(98%) $4.00 0 11 12 23 Nuristan$ *UNICEF$supports$40$District$communication$Officers$and$two$Provincial$Polio$Communication$Officers$in$Kandahar$and$Helmand.$In$the$Eastern$Region,$UNICEF$ support$22$District$communication$officers$and$three$Provincial$Polio$Communication$officers.$ Page 25 GPEI Partner Status Report - 25 September 2014 ROTARY INTERNATIONAL’S WORK IN AFGHANISTAN Rotary has a small presence in Afghanistan, but remains active in the following targeted ways: • • • • • Representing Rotary at all government Poliovirus Epidemiology and Intervention activities, and advocate at the local level with the authorities, including the Haj and Auqqaf religious department, police, education department and local Governors. Working with local influential figures and community leaders to help address refusals and change perceptions of the programme. Helping to reach children by providing funds for cross-border shelters on both the Afghanistan and Pakistan side of the border. Providing the funding and supervising the building of a dry vaccination storage facility that is being used by EPI for enhanced routine immunization. Providing funds for additional vaccinators to help address immunization requirements for travelers to India. Page 26 GPEI Partner Status Report - 25 September 2014 PERFORMANCE INDICATORS IMMUNIZATION AND SURVEILLANCE Figure 23. Six-month standard immunization indicators among children aged 6–35 months with NPAFP and annualized surveillance indicators by province, Afghanistan and Pakistan February 2013 to August 2014 Source: CDC *Data as of 2 September 2014 Page 27 GPEI Partner Status Report - 25 September 2014 GPEI POLIO ERADICATION AND ENDGAME STRATEGIC PLAN 2013–2018, AFGHANISTAN STRATEGIC PLAN OBJECTIVE OUTCOME INDICATORS (2013) RESULTS All wild poliovirus transmission stopped by the end of 2014 STATUS NA* All cVDPV cases in 2013 were either a continuation of the 2009 emergence or imported from Pakistan. There are no identified cVDPV cases in 2014 to date. NA Achieve and maintain an NPAFP rate of › 2/100,000 in all states/provinces of high-risk countries and maintain an NPAFP rate of › 2/100,000 in all states/provinces In the last 12 months, the national NPAFP rate was 11.53/100,000, an absolute 2% increase from the previous year. All provinces have maintained a NPAFP rate >2/100,000. Met Achieve and maintain adequate stool sample collection in 80% of cases in all states/ provinces Nationally, 94% of AFP cases had adequate stool specimen. All provinces have maintained adequate stool collection in >80% of AFP cases during the previous 12 months, which represents a slight increase from 97% the previous rolling year. Met LQAS passed at 80% threshold in all high-risk areas LQAS assessments continue to be limited. Using available data, of the LQAS assessments conducted in the Southern Sanctuary and Eastern Risk Area, 62% have passed the 80% threshold. Not Met Establish full safety and security framework A security management plan is in place as part of the overall security framework. Improvement of dialogue with anti-government elements (AGE) in the Southern Region resulted in improved access to children during SIAs in the South. Improvements also occurred in the Eastern Region following improved coordination with AGE, through intermediaries. Established All current cVDPV outbreaks stopped by end-2013 More than 6 months have passed since the most recent cVDPV case. All new cVDPV outbreaks stopped within 120 days OUTPUT INDICATORS (2013) Poliovirus Detection and Interruption: Complete the interruption of wild poliovirus transmission globally and more rapidly detect and interrupt any new outbreaks due to vaccinederived polioviruses Met * Not applicable Page 28 GPEI Partner Status Report - 25 September 2014 SYNOPSIS • • • • • • Epidemiology: Case counts decreased 62% in 2013 compared with 2012. However, as of 23 September during 2014 to date there were ten WPV cases compared with four cases during the same time period in 2013. Three WPV1 cases occurred in the Southern region in late 2013 and early 2014, indicating that the endemic spread of WPV1 transmission in this part of Afghanistan continues. The viruses from the two cases had circulated undetected for more than 20 months, suggesting a surveillance gap. Seventeen of the 22 WPV cases that occurred in Afghanistan during 2013–2014 to date were reported in eastern provinces bordering the KP and FATA Sanctuaries in Pakistan. Afghanistan will continue to remain at very high risk for importation of WPV as long as transmission continues in Pakistan. No cVDPV cases have been detected during 2014 to date. Immunization: From August 2013 to August 2014, the proportions of children missed in SIAs as measured by independent monitoring ranged from 5% to 13% (as high as 59% in LPDs). NPAFP data from the endemic Southern Region suggest improvements in vaccination coverage during the previous 12 months overall, except in Helmand province where SIA vaccinations were suspended during March–July 2014. Vaccinations resumed in Helmand during late August and three SIA rounds are planned. NPAFP data suggest a drop in vaccination coverage in the Eastern region (the proportion of zero-dose children increased from 1% in 2012 to 5.9% in 2013). Nationally, during 2014 to date, none of the NPAFP cases ages 6–23 months were in zero-dose children compared with 1.7% of cases during 2013. The circulation of cVDPV2 into early 2013 highlighted weaknesses in the routine immunization system in the Southern Region that appear to have been mitigated by tOPV SIAs and permanent polio team use of tOPV. Security: The security situation continues to disrupt the ability to operate but despite this, the access situation in the South has steadily improved since 2012. Negotiations through the International Committee of the Red Cross and through the ICN in the Southern Region have been successful in reducing the number of children missed because of inaccessibility, including again gaining access in Helmand in late August. Credible channels of communication have been established to engage the AGE leadership systematically through intermediaries. Surveillance: AFP performance indicators and virologic data had in the past suggested substantial surveillance gaps. In the most recent period, stool specimen adequacy has improved and virologic evidence suggested improved performance after 2010. However, detection of six divergent (>1.5% from closest link) WPV1 viruses in late 2013/2014 in Helmand, Kabul, Laghman, Nangarhar, and Uruzgan suggests some potential gaps in surveillance in the areas which need to be addressed. Ownership: At the national level, indicators suggest strong ownership within the Ministry of Public Health but variable ownership elsewhere. There is concern whether the new government, when established, will take ownership of the programme. Even now, however, meetings of the Inter-Ministerial Task Force and of high-level governors with the President have been postponed consistently. Ownership is strong among health leaders at the provincial levels but variable at the district level. Community demand: Vaccine refusal accounted for up to 25% of missed children among all current 16 LPDs in the Southern Region and represented up to 5% of targeted children in some critical districts. Trends indicate a decline in community demand from previous levels on average in the 11 LPDs, from 2.3% in January to 1.5% in July 2013. In November 2013 16% of children missed in SIAs in Afghanistan were due to refusals. Among missed children in different regions the proportion due to refusals varied from 11% in the East, 13.5% in the South and 19% in the Southeast. Page 29 GPEI Partner Status Report - 25 September 2014 PAKISTAN NATIONAL POLIO OVERVIEW Figure 24. WPV and cVDPV cases, Pakistan, 2013 and 2014 to date* The number of WPV cases in Pakistan increased from 58 in 2012 to 93 in 2013, driven by an uncontrolled outbreak in FATA since May 2013. As of 23 September, there have been 166 cases in 2014, compared with 28 for the same time period in 2013. During 2013–2014, 70% of cases occurred in FATA (mainly North Waziristan Agency) and most of the remainder in KP with other cases in Punjab, and Sindh. Cases and environmental surveillance indicate continued circulation in Sindh and KP during 2013–2014. Case numbers in Punjab decreased in the first quarter of 2014 but increased again in the second quarter compared with 2013. No WPV3 has been detected in Pakistan since April 2012. There were 19 cVDPV cases in 2014 to date (17 cases from FATA and two from KP), compared with 25 cases during the same time period in 2013. Eleven SIAs have been conducted during 2014 to date. SIAs have primarily used bOPV; tOPV has been used in the March NID and tOPV and monovalent OPV type 1 (mOPV1) have been used in select areas during SIADs and SNIDs. Violence against healthcare workers has continued sporadically and, Source: WHO *Data as of 9 September 2014 although this has adversely affected vaccination in specific locations, the programme has largely been able to maintain population immunity in those areas where access is not impeded. Because of security concerns, the programme has been unable to conduct LQAS in the majority of the country except for Karachi, where it has been used sporadically. Nonetheless, a successful series of oneday, once-a-week SIAs for 12 consecutive Sundays was completed without violence in and around Peshawar earlier this year, with strong political commitment. In response to military activity in Waziristan and the surge of IDPs from the area, 15 “Permanent Transit Posts” (PTPs) were established in South KP and three in Frontier Region Bannu to vaccinate IDPs from North Waziristan. Approximately 625,375 individuals (355,140 below 5 years of age) have been vaccinated between 30 May and 31 August, 2014. Among these 380,629 (192,889 below 5 years of age) were vaccinated at key PTPs in FR Bannu, Bannu, Hangu and Kurram Agency. Page 30 GPEI Partner Status Report - 25 September 2014 ENVIRONMENTAL SURVEILLANCE Environmental surveillance is ongoing at 30 sites throughout the country, including in two of the three poliovirus sanctuaries (all but FATA) and the Quetta Risk Area. The frequency of detection of WPV from several environmental sites declined in late 2012 and 2013 but increased in 2014. In 2012, 92 of 239 samples (38%) were positive. In 2013, 20% were positive, and in 2014 to date 33% were positive. In 2014, WPV1 was isolated with increasing frequency (57% of samples in 2014 compared to 24% in 2013) from several areas in Sindh, namely Baldia, G.Iqbal, Gadaap, and Hyderabad. WPV1 was isolated sporadically from environmental specimens from Rawalpindi and Quetta in 2013 and from many specimens from various Lahore sites during the second quarter of 2014. No WPV3 viruses have been detected in environmental specimens since October 2010. cVDPV was detected in environmental specimens from Sindh in March through May 2014 but has not been detected again since then; the last case of cVDPV detected in Sindh was in July 2013. VIROLOGY (See also maps of WPV1 by genetic cluster and cVDPV2 in the Afghanistan section of this document, Figure 9, page 14). Five genetic clusters of WPV1 were represented in specimens from polio cases and environmental specimens in the past 12 months. Viral genetic diversity and levels of virus circulation were highest in FATA. Wild virus has been exported from FATA to other parts of the country and Afghanistan. The number of cases in Punjab increased as virus spilled over from FATA. WPV1 viruses were detected from environmental samples in four provinces (Balochistan, KP, Punjab, and Sindh). One cluster of virus is localized to a specific geographic location; a single R2A virus was found in environmental specimens in Quetta in late 2013. VDPV emergence has resulted in cVDPV2 cases in Killa Abdullah district of the Quetta block, Balochistan, with onset of the first case on 30 August 2012. The most recent cVDPV2 case in Balochistan was in June 2013. cVDPV2 originating in Killa Abdullah spread to North Waziristan in FATA in April 2013, causing the ongoing outbreak. This emergence group includes 16 cases from 2014; the onset of the most recent case was 23 June 2014. The first cVDPV2 from Pakistan environmental specimens was isolated from Karachi Gadaap in week 16 of 2013, and the most recent was isolated 20 May 2014 (related to North Waziristan emergence cluster; the most recent isolate from the Kabul emergence cluster was on 14 March). A separate emergence group (N. Waziristan) consists of five cases from 26 August 2013 to 11 January 2014. Two independent ambiguous VDPV2 (aVDPV2s) were detected in AFP cases in FATA in the past 12 months. The potential for surveillance gaps exists at the sub-national level, as evidenced by chains of transmission that were detected only from environmental surveillance. The percentage of WPV1 isolates (from AFP surveillance) with much less genetic linkage than expected has declined from 21% in 2009 to 5% in 2012 and 5% during the reporting period (9/178 isolates from AFP cases). 1. Both WPV1 and cVDPV2 circulation increased during 2013–2014 compared with 2012, due principally to ongoing outbreaks in FATA. 2. Viral genetic diversity and levels of virus circulation were highest in FATA in 2013. 3. The percentage of WPV1 isolates with less genetic linkage than expected has remained stable from 2012 to the present. However, detection of long-standing WPV circulation only by environmental surveillance provides virologic evidence of gaps in AFP surveillance. Page 31 GPEI Partner Status Report - 25 September 2014 Figure 25. WPV1 and cVDPV2 cases and environmental isolates by genetic cluster (WPV1) and emergence (cVDPV2), Pakistan, 12 August 2013 to 11 August 2014* WPV1 cVDPV2 Source: CDC * Data as of 20 August 2014 POLIOVIRUS SANCTUARIES AND RISK AREAS At the time of this report, Pakistan has three designated virus sanctuaries and one risk area: 1. 2. 3. 4. Federally Administered Tribal Areas (FATA) Sanctuary Central and Southern districts of Khyber Pakhtunkhwa province (KP) Sanctuary Karachi Sanctuary Quetta Risk Area The Quetta block (Quetta, Killa Abdullah, and Pishin) had been included as a sanctuary previously. Evidence suggests that indigenous poliovirus is no longer circulating there since late 2013, although poor performance indicators indicate ongoing risk. This area is now considered to be the Quetta Risk Area. Page 32 GPEI Partner Status Report - 25 September 2014 FATA POLIOVIRUS SANCTUARY Figure 26. WPV and cVDPV cases, FATA Sanctuary, 3 September 2013 to 2 September 2014* Source: WHO *Data as of 9 September 2014 LQAS surveys provide an assessment of SIA quality through a limited sample obtained from random cluster sampling. LQAS surveys in many areas affected by conflict or security problems in Pakistan have not been conducted at all, to avoid raising the visibility of the programme, or are not conducted in randomly selected areas but rather in areas selected based on feasibility regarding the security situation. This will lead to correspondingly biased results that may overstate SIA quality. Other notes regarding LQAS: • Pakistan has continued to use “old” decision rules (‘O’) of 0-5, 6-7, 8-12 and ≥13 for samples of five clusters of 10 children (50) and six clusters of 10 (60) for testing at thresholds of 95%, 90%, and 80%. These rules overstate SIA quality. Please refer to discussion of methodological limitations in previous reports. • “New” decision rules (‘N’) of 0, 1-2, 3-6, and 7-50 for sample sizes of 50 and 0, 1-3, 4-8, and 9-60 for sample sizes of 60 provide a more reasonable quality assessment at 95% (High Pass), 90% (Pass), and 80% (Low) thresholds (or Fail if below) for programmatic purposes under the same assumption of variability. Page 33 GPEI Partner Status Report - 25 September 2014 ! Figure 27. WPV cases by week of onset and environmental surveillance results, FATA Sanctuary, Pakistan, 3 Sept 2013 – 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Note: An aVDPV case recently re-classified as a cVDPV case is not included in Figure 27. Since June 2012, SIAs have not been conducted in North or South Waziristan or in parts of Khyber Agency. Figure 28. Proportion of Union Councils with LQAS survey results by SIA, FATA Sanctuary, Pakistan, Sept 2013 to Aug 2014 Note: LQAS not conducted in FATA from March to August 2014. Since June 2012, SIAs have not been conducted in North or South Waziristan or in parts of Khyber Agency. Figures 29. Proportion of NPAFP cases 6 to 35 months, by OPV status, FATA Sanctuary, Pakistan** Source: WHO **Data as of 2 September 2014 Page 34 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of Union Councils with indicators met for each campaign Jan '14 R1 Jan '14 R2 Feb '14 R1 Feb '14 R2 Mar '14 R1 Mar '14 R2 Apr '14 R1 Apr '14 R1 May '14 R1 May '14 R2 FATA Sanctuary UPEC meeting held Jun '14 53 39 77 58 32 72 26 UPEC chaired by UCMO 100 100 100 100 100 100 100 Microplan Validated 94 94 95 95 94 92 77 ≥1 Government member 87 90 92 88 87 72 ≥1 Local member 99 99 97 98 97 82 ≥1 Female member 13 12 14 14 14 11 Jul '14 Percent of teams with indicators met for each campaign Abbreviations: UPEC=Union Council Polio Eradication Committee No campaign UCMO=Union Council Medical Officer No data Source: Pakistan National Emergency Action Plan Indicators, WHO-Pakistan ------------------------------------------------------------------------------------------------------------------------CENTRAL AND SOUTHERN KHYBER-PAKHTUNKHWA SANCTUARY Figure 30. WPV and cVDPV cases, KP Sanctuary, 3 September 2013 to 2 September 2014* This reservoir consists of Central KP (Peshawar, Nowshera, Swabi, Charsaddah, Mardan districts) and Southern KP (Bannu, Tank, Lakki Marwat districts). Data to follow are presented for the entire province. Source: WHO *Data as of 9 September 2014 Page 35 GPEI Partner Status Report - 25 September 2014 Figure 31. WPV cases by week of onset and environmental surveillance results, KP Sanctuary, Pakistan, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Figure 32. Proportion of Union Councils with LQAS survey results by SIA, KP Sanctuary, Pakistan, Sept 2013 to Aug 2014 Note: LQAS not conducted in KP from March to August 2014. Figure 33. Proportion of NPAFP cases 6 to 35 months, by OPV status, KP Sanctuary, Pakistan** Source: WHO **Data as of 2 September 2014 Page 36 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of Union Councils with indicators met for each campaign Jan '14 R1 Jan '14 R2 Feb '14 R1 Feb '14 R2 Mar '14 R1 Mar '14 R2 Apr '14 R1 Apr '14 R1 May '14 R1 May '14 R2 KP Sanctuary UPEC meeting held UPEC chaired by UCMO Jun '14 26 Jul '14 53 73 46 84 68 85 99 100 100 100 100 100 100 100 100 17 85 72 Microplan Validated 71 ≥1 Government 80 95 76 ≥1 Local 78 99 100 ≥1 Female 53 63 49 Percent of teams with indicators met for each campaign Abbreviations: UPEC=Union Council Polio Eradication Committee No campaign UCMO=Union Council Medical Officer No data Source: Pakistan National Emergency Action Plan Indicators, WHO-Pakistan ------------------------------------------------------------------------------------------------------------------------- KARACHI POLIOVIRUS SANCTUARY Figure 34. WPV & cVDPV cases and environmental surveillance results, Karachi Sanctuary, 3 September 2013 to 2 September 2014* All of Karachi is currently serving as the WPV reservoir within Sindh. Source: WHO *Data as of 9 September 2014 Page 37 GPEI Partner Status Report - 25 September 2014 Figure 35. WPV cases by week of onset and environmental surveillance results, Karachi Sanctuary, Pakistan, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Figure 36. Proportion of union councils with LQAS survey results* by SIA, Karachi Sanctuary, Pakistan, Sept to Aug 2014 Figure 37. Proportion of NPAFP cases 6 to 35 months, by OPV status, Karachi Sanctuary, Pakistan** Source: WHO **Data as of 2 September 2014 Page 38 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of Union Councils with indicators met for each campaign Jan '14 R1 Jan '14 R2 Feb '14 R1 Feb '14 R2 Mar '14 R1 Mar '14 R2 Apr '14 R1 Apr '14 R1 May '14 R1 May '14 R2 Sindh UPEC meeting held 89 Jun '14 Jul '14 100 94 99 78 50 UPEC chaired by UCMO 100 100 100 100 100 Microplan Validated 99 99 98 100 86 ≥ 1 Government member 96 98 97 97 86 ≥ 1 Local member 98 99 98 99 84 ≥ 1 Female member 92 92 93 91 78 Percent of teams with indicators met for each campaign Abbreviations: UPEC=Union Council Polio Eradication Committee No campaign UCMO=Union Council Medical Officer No data Source: Pakistan National Emergency Action Plan Indicators, WHO-Pakistan Data shown above are for all of Sindh Province _________________________________________________________________________________ QUETTA RISK AREA (THE THREE HIGH-RISK DISTRICTS OF QUETTA, KILLA ABDULLAH, AND PISHIN) Figure 38. WPV and cVDPV2 cases, Quetta Risk Area, 3 September 2013 to 2 September 2014* All endemic WPV circulation within the Quetta block has apparently been interruped. Pishin, Killa Abdulah and Quetta now consitute a risk zone for reintroduction of WPV. Note: an additional case in Quetta block (in Quetta district) with onset in August was recently confirmed. Source: WHO *Data as of 9 September 2014 Page 39 GPEI Partner Status Report - 25 September 2014 Figure 39. WPV cases by week of onset and environmental surveillance results, Quetta Risk Area, Pakistan 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Figure 40. Proportion of Union Councils with LQAS survey results* by SIA, Quetta Risk Area, Sept 2013 to Aug 2014 Note: LQAS not conducted in Quetta from May to August 2014. Figure 41. Proportion of NPAFP cases 6 to 35 months, by OPV status, Quetta Risk Area, Pakistan** Source: WHO **Data as of 2 September 2014 Page 40 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of Union Councils with indicators met for each campaign Jan '14 R1 Jan '14 R2 Feb '14 R1 Feb '14 R2 Mar '14 R1 Mar '14 R2 Apr '14 R1 Apr '14 R1 May '14 R1 May '14 R2 Balochistan UPEC meeting held 9 Jun '14 48 29 66 34 85 100 UPEC chaired by UCMO 100 100 100 99 100 100 100 Microplan Validated 69 88 92 90 100 100 66 ≥ 1 Government member 69 49 ≥ 1 Local member 96 75 ≥ 1 Female member 52 75 Jul '14 17 Percent of teams with indicators met for each campaign 90 64 90 84 Abbreviations: UPEC=Union Council Polio Eradication Committee UCMO=Union Council Medical Officer 81 69 87 52 100 89 92 62 51 53 27 67 No campaign No data Source: Pakistan National Emergency Action Plan Indicators, WHO-Pakistan Data shown above are for all of the Balochistan Province ------------------------------------------------------------------------------------------------------------------------- COMMUNICATION AND SOCIAL MOBILIZATION HIGH DEMAND, BUT CRACKS ARE SURFACING Figure 42. Despite Pakistan’s challenges, the overwhelming majority of Pakistan’s parents and caregivers willingly vaccinate their children in polio campaigns. Until April 2014, the aggregate high-risk area refusal proportion had fallen more than 80% since 2013 to just 0.1% - the lowest proportion of polio-endemic countries globally. However, parents in KP and Karachi are starting to show their fatigue. The refusal proportion in Pakistan has gone back up to January 2013 levels, predominantly because of repeated dose refusals in these two areas. Nearly 15% of 2014’s cases now come from refusal families, compared with 5.5% last year. Although the refusal proportion is still miniscule among targeted children, the data show that refusal families are clustered in under-vaccinated communities, and can be extremely dangerous. All polio cases come from families with no formal education. This, together with Harvard polling data showing that 11% of all parents in FATA have never heard of polio or a disease that causes paralysis, demonstrates that more must be done to reach these families with more targeted communication methods: innovative voice, inter-personal or electronic messages and dialogue. Page 41 GPEI Partner Status Report - 25 September 2014 In Bannu District, where most IDPs from North Waziristan settled following the military operation, refusals are being reported from all Union Councils (UCs), with 29 UCs reporting end of campaign refusal rates above 3%. The primary reasons for refusals since June have been “repeated campaign”, misconceptions and religious. A focus group discussion held with IDPs based in Bannu in July revealed that parents wanted more information about the effectiveness and ingredients of the vaccine. Most parents who were refusing understood the consequence of not vaccinating but were prepared to take the risk. Refusals have reportedly already come down from their peak of 15,000 in July to 9,000 by end of August REACHING CHILDREN ON THE MOVE This year, to date, 74% of all polio cases are from four tribal groups of FATA’s North and South Waziristan, where 290,000 children have been inaccessible because of a militant ban on polio vaccination since June 2012. The military operation launched in May has resulted in the mass exodus of displaced people from North Waziristan, providing the programme with its long-awaited opportunity to vaccinate these children. UNICEF’s COMNet, which was already working in North and South Waziristan to facilitate the use of functioning health centers and encourage self-vaccination by caregivers of unprotected children, has travelled out with these families to FR Bannu and neighboring districts and is actively engaging these communities for polio vaccination. UNICEF’s four provincial offices have adopted an ‘All for FATA’ approach to identify the four priority tribal groups that dominate poliovirus transmission wherever they are throughout the country. UNICEF’s goal is to build community trust and to ensure that the tribal groups are reached with language- and issue-specific messaging, are identified and included in microplans, and reached during campaigns and in transit. To ensure immediate response to the large scale displacement from North Waziristan, 241 mobilizers were trained and deployed in FATA and South KP districts of FR Bannu, Bannu, Lakki Marwat, DI Khan, Kohat and Hangu. Figure 43. Close coordination with Afghanistan to track immunization and security in border areas has contributed to the now-high coverage across the borders. All this groundwork has contributed to near-universal acceptance of the vaccine at transit points, refugee and IDP camps and among nearby host communities. Nearly two million were vaccinated at transit points in June 2014, and more than one million have been vaccinated each month since January of this year. Page 42 GPEI Partner Status Report - 25 September 2014 REACHING MISSED CHILDREN IN ACCESSIBLE AREAS With refusals no longer a primary reason for missing children, UNICEF has focused much of its attention to reaching and facilitating immunization of the approximately 100,000 children in accessible areas missed because of poor campaign quality. Many of these children are missed at the doorstep because they are out of the home or the district, because vaccinators have the wrong profile (too young, not from the local community) or they lack the IPC skills to identify all children in the household or convince the caregiver to bring all children to the doorstep for vaccination. Multi-layered social data down to the UC level helps UNICEF identify and increasingly reach children who are ‘Not Available’ in campaigns. Literacy levels, media preferences, seasonal migration patterns, routes and livelihood choices are analyzed and strategies redesigned to ensure that vaccine is available at the right time and place to maximize each chance to reach every child. On average, more than 70% of children can be found within their district when vaccinators arrive, and can be recovered with adequate revisit and outof-house vaccination strategies. Most children are visiting relatives and should be reached at other households. Figure 44. Summary of information on unavailable children, Pakistan February–June 2014 The IMB in May challenged COMNet to double its initial absence recovery rate of 40%. Since then, COMNet has been fairly consistent in recovering more than 60% of children absent, but the figures fluctuate, indicating that this is not yet a systematic standard across the network. Absence conversion has been included as a key performance indicator as part of frontline worker performance monitoring. Given the social and operational strategies needed to recover children out of the house, all partners must be held accountable for raising this conversion rate. Page 43 GPEI Partner Status Report - 25 September 2014 ENGAGING COMMUNITIES FOR ACCESS The Pakistan programme has rejected the mentality of “waiting for access to open up” before acting, and has focused on proactive efforts that allow access to children even in the most challenging circumstances. Until August, 74,000 children under age five remained in South Waziristan, but door-to-door campaigns could only access 8,000 (11%) of them. Two months ago, COMNet staff identified religious influencers and held a series of meetings with the Taliban/Mujahedeen for accessing the remaining 66,000 inaccessible Wazir children Figure 45. with door-to-door campaigns. At the same time, more than 20 COMNet staff have been working in South Waziristan to help caregivers facilitate selfadminister OPV inside their homes for those who could not be reached with campaigns. From March to July, 1,184 children were selfvaccinated and many more families sensitized about the importance of vaccination. In July, COMNet also facilitated free health camps operated by the military and Government health authorities, which vaccinated 2,054 children. They also performed a cold chain inventory of the 22 registered health facilities in South Waziristan, of which only half were found to have functional EPI centers. The negotiations with the Taliban also bore fruit in August, with access to 91% of the children <5 years of age in South Waziristan achieved through health facility-based vaccination. Agreement was also granted for door-to-door polio vaccination in the 13 previously inaccessible areas. Campaigns are to start in September. ENGAGING WOMEN UNICEF is adding a fourth tier of female community mobilizers to the COMNet structure as an innovative approach to raising the proportion of female mobilizers. More than 500 Female Community Mobilizers will be hired in the next quarter to focus specifically on mothers, and on reaching newborns and children under age 2 years within households. The Female Community Mobilizers will be deployed in top priority high-risk areas where children are being consistently missed during campaigns. Page 44 GPEI Partner Status Report - 25 September 2014 PROGRAMME INFORMATION ACCESSIBILITY AND SECURITY Pakistan remains a politically volatile country during 2013-14 with no signs that stability is on the horizon as political protests continue across the country and Islamabad, in particular. In June 2012 various Pakistan Taliban elements issued a ban on polio vaccinations citing numerous reasons, including the belief that the polio programme was a cover for a U.S. spying campaign and the ongoing use of drone strikes. This led to North Waziristan as well as large areas in South Waziristan becoming completely inaccessible to polio workers. Figure 46. Inaccessible areas during the August 2014 SIA and 2014 WPV1 and cVDPV cases, Pakistan* Source: WHO *Data as of 9 September 2014 In all of Pakistan, between June 2012 and January 2014, 24 killings occurred (10 each in 2012 and 2013 and four in 2014) that could be reasonably attributed to the victims’ connection with polio. In addition, there were 36 deaths, mainly of security escorts, where the link to polio is unclear. Also, numerous reported cases of intimidation serve to create fear and panic among polio workers leading to areas becoming inaccessible. In June, the Pakistan Military launched Operation Zarb-e-Azb in North and South Waziristan to drive militant factions out of those areas. Many such operations have been conducted previously with varying degrees of success. This current operation has led to almost a million IDPs appearing in the settled areas around Waziristan and neighboring Afghanistan. This has created opportunities to access children from North Waziristan who have been unvaccinated for two years but it has also led to the threat of the spread of polio from North Waziristan across other areas of Pakistan and Afghanistan. SIAs targeting IDPS were successfully implemented in southern KP districts and FATA agencies. It is vital that the local context of the security and access situation is fully understood and that such information is acted upon immediately. In this regard, analysis that has been carried out in the FR Bannu, where children Page 45 GPEI Partner Status Report - 25 September 2014 were missed in four areas for ‘security reasons’ and fear, revealed reasons different from those of the neighboring areas. A plan has been put in place to gain access to these missed children. Local COMNet staff have proven to be successful in understanding local security and accessibility issues. In particular, work is being developed to facilitate the easy and rapid two-way flow of information between polio workers (including COMNet staff) with higher levels, which will allow warnings to be raised in a timely manner and for local cases of inaccessibility to be addressed immediately. This approach, which has been proven effective in reducing community/parental refusals will greatly assist in improved reporting on security and accessibility. HUMAN RESOURCES Location (sanctuary) FATA * KP (province) KP (High risk districts: Peshawar, Charsadda, Mardan, Nowshehra, Lakki Marwat) Karachi (three high-risk towns: Baldia, Gadap, and Gulshen Iqbal) Quetta (Quetta, Killa Abdullah, and Pishin districts) Total number of house to house vaccination teams Number (%) of house to Number (%) of Salary per house vaccination teams house to house with at least one female vaccination teams vaccinator per day member with a local member 2,169 299 (14%) 2118 (98%) $3.50 19,358 10043 (52%) 16530 (85%) $2.50 Remarks $1.00 additional, since FATA is a region with security hazard See below for high risk districts Peshawar (since February 2014), Mardan, Charsadda and Swabi (since April 2014) are conducting SIAs in one day and paying $5.00 per day, while Lakki Marwat in 3 days 9,424 5543 (59%) 9424 (100%) $5.00 2,887 2,773 (96%) 2,757 (95%) $5.00 Karachi is implementing the SIAs in one day since mid March 2014 1,609 877 (55%) 1,421 (88%) $5.00 $2.5 paid through Partner (WHO) and $2.5 paid by the provincial Government * Accessible areas only ROTARY INTERNATIONAL’S WORK IN PAKISTAN Rotarians in Pakistan have developed a targeted strategy for outreach related to polio eradication activities in alignment with the National Emergency Action Plan. This involves Rotarians participating in high level meetings with the President, district heads, and health ministers, as well as outreach to corporate and NGO partners to help build broader support for the programme. Rotarians have worked with Coca Cola Pakistan to raise awareness through billboards, and at the reverse-osmosis water filtration plants in high-risk areas. A new partnership with Telenor provides e-monitoring through the use of cell phones for female health workers, community mid-wives, and health facility managers. Rotarians are helping to raise awareness among influential persons in high-risk communities through polio orientation and planning workshops, as well as Ulema polio awareness workshops. The Speaking Book project has served as an educational tool for use at polio resource centers and in schools. Rotarians in Pakistan have addressed the inaccessibility issue in high-risk areas through the development of Polio Resource Centers, which are organized in collaboration with local NGOs. They provide social mobilization and health services along with polio vaccines. Nine centers have reached more than 111,000 children and helped convert more than 8,500 refusals. The resource centers are located in the following communities: • Killa Abdullah • Pashin • Loralai • Gulshan Town-Karachi Page 46 GPEI Partner Status Report - 25 September 2014 • • • • • Mirpurkhas Nowshera Peshawar City Peshawar Khairun Nas Turbat Rotary Clubs have also created permanent immunization centers in 14 areas, mostly located in Karachi and Lahore, and established permanent transit posts in 10 areas, with four additional transit posts in process, which have helped to cover more than 9 million children. The transit posts are located at the following points: • Super Highway-Karachi (two posts) • National Highway- Karachi • Zoological Garden-Karachi City • Mandi More-Rawalpindi • Attock-G.T Road • Killa Abdullah • Chaman- Pak Afghan Border • Torkhum- Pak Afghan border • Jaccobabad-Sindh • Gujranwala- Punjab Rotarians are working on developing mobile vaccination services at railways, and in collaboration with WHO and the provincial government, planning to reach children located in high-rise buildings and public places through the installation of 18 kiosks, with an additional 60 planned. PERFORMANCE INDICATORS IMMUNIZATION AND SURVEILLANCE (See Figure 23, Six-month standard immunization indicators among children aged 6–35 months with NPAFP and annualized surveillance indicators by province, Afghanistan and Pakistan February 2013 to August 2014, on page 28). Page 47 GPEI Partner Status Report - 25 September 2014 GPEI POLIO ERADICATION AND ENDGAME STRATEGIC PLAN 2013–2018, PAKISTAN STRATEGIC! PLAN! OBJECTIVE! OUTCOME!INDICATORS! (2013)! RESULTS! All!wild!poliovirus!transmission! !! stopped!by!the!end!of!2014! ! Poliovirus! Detection!and! Interruption:! Complete! the! interruption! of!wild! poliovirus! transmission! globally!and! more! rapidly!detect! and!interrupt! any!new! outbreaks!due! to!vaccineM derived! polioviruses! ! All!new!cVDPV!outbreaks! stopped!within!120!days! Most!cVDPV!cases!in!2013!were!continuation! of!2012!emergence.!After!a!new!emergence!in! North!Waziristan,!all!reported!cases!occurred! within!5!months!from!first!to!most!recently! confirmed!case.! OUTPUT!INDICATORS!(2013)! !! Achieve!and!maintain!an! NPAFP!rate!of!›!2/100,000!in! all!states/provinces!of!highM risk!countries!and!maintain!an! NPAFP!rate!of!›!2/100,000!in! all!states/provinces!! National!NPAFP!rate!during!16!August!2013!to! 15!August!2014!period!was!5.6/100,000,!a!0.4%! decrease!from!the!previous!rolling!year.!Only! 75%!of!provinces!have!maintained!NPAFP! >2/100,000!this!time,!compared!with!87.5%! the!previous!rolling!year.! Achieve!and!maintain! adequate!stool!sample! collection!in!80%!of!cases!in!all! states/provinces!! LQAS!passed!at!90%!threshold! in!all!highMrisk!areas! Establish!full!safety!and! security! framework!! All!current!cVDPV!outbreaks! stopped!by!endM2013! Nationally!the!proportion!of!AFP!cases!with! adequate!stool!was!93%,!marking!an!absolute! 3%!increase!from!the!previous!period.!All! provinces!have!maintained!adequate!stool! collection!in!>80%!of!AFP!cases!during!16! August!2013!to!16!August!2014.!This! represents!an!absolute!12.5%!increase!from! the!previous!year.! Over!the!last!12!months,!of!the!649!LQAS! assessments!conducted!in!the!sanctuaries!and! risk!area,!4%!have!passed!at!the!90%!threshold! and!22%!have!passed!at!the!80%!threshold.! Performance!has!been!particularly!poor!in! Quetta.! A!plan!to!provide!security!to!UN!polio!workers! has!been!developed!and!is!supported!by!all! stakeholders.!A!framework!for!operating!in! insecure!areas!has!been!incorporated!into!the! current!version!of!the!National!Emergency! Action!Plan.!Discussions!and!efforts!with! provincial!and!national!authorities!continue!to! enhance!security!for!all!government!health! workers!involved!in!SIAs,! Circulation!in!2012!and!2013!after!!emergence! in!2012!was!not!interrupted!by!endM2013! STATUS! NA*!! NA!! !! Not Fully Met! Met! Not!Met! Established!! Not!Met! * Not applicable Page 48 GPEI Partner Status Report - 25 September 2014 SYNOPSIS • • • • • • Epidemiology: An ongoing outbreak of WPV1 and cVDPV2 in the population from North Waziristan that started around April 2013 and has caused a surge in cases and exportation to Afghanistan and other parts of Pakistan. There are more than four times as many WPV1 cases during 2014 to date as there was during the same time period in 2013. During 2014, 93% of cases were reported among children aged <36 months. Among them, 67% received no OPV doses from routine or supplemental immunizations. During 2014, WPV1 cases were reported in 21 (13%) of 157 districts compared with 15 (10%) districts in 2013. Most WPV1 cases reported during 2014 were from FATA and KP (71% and 18% respectively), 57% of cases in FATA were from North Waziristan. The incidence of cVDPV cases has decreased in 2014 with most cases occurring in FATA (FR Bannu and North Waziristan); however isolation continued from environmental surveillance sites in Sindh. Immunization: Polio vaccination has not resumed in North Waziristan but immunization activities targeted populations displaced by military action in North Waziristan. Through the use of transit posts, border vaccination teams, and vaccinations at IDP camps, children leaving North Waziristan were vaccinated. In FATA, during 2014 to date, 61% of non-polio AFP cases ages 6–23 months were zero-dose children and 25−34% of children were inaccessible during SIAs. The ongoing detection of cVDPV among cases and in environmental specimens indicates the presence of immunity gaps than remain mainly in populations that have been inaccessible. Security: Pakistan’s political and security situations will remain unstable for the foreseeable future. However, the population movements resulting from the current military offensive has provided the opportunity to vaccinate the majority of hard-to-reach children located particularly in North Waziristan. The remaining pockets of inaccessibility should now be the focus to help interrupt WPV transmission in Pakistan. The completion of 12 consecutive Sunday vaccination campaigns in Peshawar earlier this year provides an example of how, with strong political commitment, SIAs can be carried out without violence. To conduct similar large scale “protected campaigns” in the high-risk UCs of Karachi, high-level commitment and support from both the political parties in control of Sindh province and Greater Karachi is critical. Engagement with the Military is also necessary to be able to fully exploit access to Bara Tehsil in Khyber Agency, and to get a better sense of when the Military might provide access to conduct vaccination activities in North Waziristan. This engagement should follow the agreed protocols of the POB-endorsed approach. i.e., military or local law enforcement forces will not be directly involved in administering vaccines, and that the use of military will be time-limited and considered as a last resort Surveillance: Although overall strong, some indicators suggest decreased surveillance performance. The percentage of WPV1 isolates with less genetic linkage than expected has decreased since 2012. Detection of long-standing WPV circulation only by environmental surveillance provides virologic evidence of gaps in AFP surveillance. Analysis of NPAFP cases and surveillance indicators suggests some underreporting of cases in FATA. Ownership: The high degree of political commitment in KP is encouraging and has already produced concrete results. The declining number of UPEC meetings held in each area, particularly in FATA and Quetta, is concerning. On 12 September, the Government of Pakistan signed a loan agreement with the Islamic Development Bank for program implementation. Although encouraging, the lengthy delay in signing resulted in the scaling back of SIAs scheduled in September. The decision of the Prime Minister on the IMB and Technical Advisory Group recommendations to establish federal and provincial emergency operations centers is still pending. Community Demand: Despite Pakistan’s challenges, the overwhelming majority of Pakistan’s parents and caregivers willingly vaccinate their children in polio campaigns. More than 99% of parents in most parts of the country accept vaccine for their children if vaccinators reach the doorstep. However, parents in KP and Karachi are starting to show their fatigue. The refusal rate has increased by 80% over the past 3 months in these two areas, predominantly because of repeated doses. Nearly 15% of Pakistan’s 2014’s cases now come from refusal families, compared with 5.5% last year. Although the refusal proportion is still miniscule, the data show that refusal families are clustered in under-vaccinated communities, and can be extremely challenging. Page 49 GPEI Partner Status Report - 25 September 2014 NIGERIA NATIONAL POLIO OVERVIEW Figure 47. WPV and cVDPV cases, Nigeria, 2013 and 2014 to date* The number of WPV cases in Nigeria decreased from 122 in 2012 to 53 in 2013. As of 9 September 2014, there were six WPV cases year-to-date, compared with 46 during the same period in 2013. No WPV3 has been detected since November of 2012. Since September 2012, no WPV cases have been reported in the Northwest (Sokoto, Zamfara as well as Kebbi) and since 9 September 2013, WPV cases have been limited to Kano State (most recent case, 24 July 2014) and Borno/Yobe (19 April 2014). The most recent WPV cases have all occurred in rural local government areas (LGAs) in southern Kano, in what the programme considers a “transmission zone” cVDPV case numbers have increased, from eight in 2012 and four in 2013 to 19 so far in 2014, 13 of which have occurred since May. Seven of these cases have occurred in Kano and 12 in Borno. Environmental surveillance has repeatedly detected cVDPVs in Sokoto and Borno since mid2013 and sporadically in Kano and in Kaduna more recently. Throughout 2013 and continuing into 2014, Nigeria implemented a broad array of innovations in its polio programme, with substantial improvement in SIA quality as measured by LQAS, especially in Kano State. Among the 85 highest-risk LGAs in Source: WHO *Data as of 9 September 2014 northern Nigeria, >80% have achieved the “≥80%” threshold on LQAS (i.e., eight or fewer missed children out of 60) since January and >90% have achieved this threshold since May. Much of the programme’s attention is currently focused on two transmission zones: the “Kano” zone, which includes non-urban LGAs in the south of the state as well as LGAs in north-eastern Kaduna State and northwestern Bauchi State, and the Borno/Yobe zone. In Kano State, operations are being led by a very assertive emergency operations Centre (EOC) headquartered in Kano City. A number of changes have been made to the programme, such as: Page 50 GPEI Partner Status Report - 25 September 2014 1) An extensive, state-wide walk-through microplanning exercise earlier this year resulted in an almost 50% reduction in the target population for SIAs (children under 5 years of age). 2) The programme has been treating any new WPV case as an outbreak. After the July case in Sumaila LGA, the EOC moved temporarily to the affected LGA and rapidly organized together with the national programme three outbreak response SIAs to supplement the SNIDs already scheduled. 3) A Vaccination Tracking System (VTS) technology uses the GPS in mobile phones to monitor the geographical movements of vaccination teams across Kano. This tool improves accountability by ensuring that teams are in their assigned areas and provides another means of understanding campaign quality, identifying areas that have been missed. The VTS shows increased geocoverage in Kano—from 82% of the microplan area in February 2013 to 90% in August 2014. 4) A “Hard-to-Reach” project was rolled out in May in 751 settlements from 109 wards across 27 LGAs. This project aims to deliver at least four doses of polio vaccine to all children 0–59 months of age in these hard-to-reach and underserved settlements. Alongside its goal of increasing overall immunity in these vulnerable areas by June 2015, the project is also delivering basic health services to these communities, which are outside of the reach of existing health facilities. A similar initiative is underway in five other states—Bauchi, Borno, Yobe, Kaduna and Katsina—targeting more than 2,500 settlements. The national programme is looking into implementing additional measures, including “directly observed polio vaccination” to improve team performance in areas with poor performance or a history of non-compliance and “health camps” to help build community confidence in the programme. Additionally, 15 hard-toreach/rural LGAs around the border of Kano state have been selected for a 3-month PEI/routine immunization intensification between September and December 2014. The intensification efforts will include accelerating routine immunization activities, increasing supervision in SIAs, and strengthening surveillance. In Borno and Yobe, and recently in northern parts of Adamawa, insecurity continues to be an overriding factor, particularly in a band of LGAs south of Maiduguri stretching from Yobe to Cameroon. The programme has continued innovations previously described, including permanent health teams, transit-point vaccination, vaccination in camps for IDPs, “hit and run” vaccination (rapid implementation of short-interval SIAs to take advantage of openings in inaccessible zones), and “health camps” (fixed-point vaccination centers providing a variety of health services during SIAs). A strategy that will be expanded before the end of the year is the vaccination of children at malnutrition treatment centers in Borno, linked to communities by referrals from over 550 volunteer community mobilizers (VCMs). In addition, for the first time in Nigeria, IPV was included as part of SIAs in Borno (entire state) and Yobe (selected wards in seven LGAs). The campaign took place in two phases, in June and August. The target group was 1.7 million children 14 weeks to 59 months old. While much of the programme’s attention has been set on interrupting the last remaining chains of WPV1 transmission by the end of 2014, cVDPV circulation has expanded. Nigeria has experienced a prolonged outbreak of cVDPV2 since 2005, peaking at 155 cases in 2009. By early 2012, a series of tOPV SIAs had mostly but not entirely stopped new emergences from that outbreak but did not eliminate the dominant lineage. cVDPV2 currently circulating in Nigeria is from both that outbreak and from a 2012–2013 cVDPV2 outbreak in Chad that spread to Nigeria and Cameroon. Driving the cVDPV outbreak in Nigeria is the extremely low routine immunization coverage in the north and the almost exclusive use of bOPV during SIAs between April 2013 and June 2014 (with no planned SIA during Ramadan in July, except in parts of the North-Central sanctuary). Additionally, because of violence during the prior month, Borno and Kano did not participate in the March 2013 tOPV SIA. To address low poliovirus 2 immunity, the programme conducted a tOPV SIA in August 2014 and plans a second in November. tOPV was also used in Borno during the December 2013 SIA, in selected areas of Borno in February and May 2014, and in Adamawa in February Page 51 GPEI Partner Status Report - 25 September 2014 2014. In addition, the programme has used IPV throughout Borno and parts of Yobe. Nigeria’s Expert Review Committee recently recommended that IPV also be used in southern Kano to boost population immunity and accelerate interruption of WPV transmission. The polio programme supports targeted effort to improve routine immunization in key areas, including 76 LGAs in the endemic northern States with weak routine immunization coverage and at high risk of cVDPVs. Capacity building to improve Reaching Every Ward implementation is underway in Taraba and Adamawa. AFP surveillance performance indicators have steadily improved in Nigeria in recent years, with the national NPAFP rate now exceeding 13 per 100,000 children <15 years of age per year and a national stool adequacy proportion of 97%. In Both Borno and Yobe, NPAFP reporting rates are increased over last year, to 14.7 per 100,000 children <15 years per year in Borno and 12.4 per 100,000 children <15 years per year in Yobe, and stool adequacy proportions exceed 98%. In upcoming months, Nigeria faces two potential disruptions to its polio programme: the general elections in early 2015 and the threat of further importations or spread of Ebola. In addition, the programme has a funding gap of US $22 million for 2014 and $178 million for 2015. VIROLOGY During August 2013 through August 2014 the number of genetic lineages declined compared with the previous 12-month period. Four clusters (N5A1, N5A2, N5A3 and N7B) were active, associated with cases during 2013 whereas only one cluster (N5A3) was detected from AFP cases during 2014 and one other (N5A1) detected through environmental surveillance. Cluster N5A3 detection was localized to only two NorthCentral/Northeast Sanctuary states (Kano and Yobe) in 2014. The most recent isolate corresponded to an AFP case in Kano with onset date of 24 July 2014 and closely related to local circulation within the state. Between August and December 2013, three WPV1 cluster N7B viruses were detected, circulating within Borno state in the Northeast sanctuary and one virus was detected in Kano state. The most recent case in cluster N7B was in Borno with onset date 15 December 2013. Orphan viruses were detected in five AFP cases, three in cluster N5A3 and two in cluster N7B. An additional WPV1 orphan virus (cluster N5A1) was detected in an environmental sample from Kaduna state collected 5 May 2014. During the reporting period, two WPV1 were isolated from environmental specimens collected in two sites. The WPV1 isolated from Kaduna environmental samples was detected in early May 2014, an orphan virus related to a lineage in cluster N5A1 circulating in Kano in 2013 and Katsina in 2012. The only other WPV1 detected in environmental samples was from Borno in week 42 (October) of 2013 and was from cluster N7B. Genomic sequence analysis reveals continued surveillance gaps, including some chains of WPV transmission during 2013 and 2014 that went undetected for more than a year. Viruses from AFP cases from three states (Borno, Kaduna, and Yobe) had less genetic linkage than expected with sensitive AFP surveillance. Nationally, the percentage of WPV1 isolates with much less genetic linkage than expected declined substantially from 88% (7 of 8 positives) during 2010 to 13% (12 of 103) during 2012 but it has increased to 33% (2 of 6) during the reporting period. 1. The genetic diversity of WPV1 strains has declined during August 2013 through August 2014 compared with the previous 12-month period. 2. WPV1 isolation from environmental specimens remained low during the reporting period. 3. Virologic data indicate continued gaps in AFP surveillance. Page 52 GPEI Partner Status Report - 25 September 2014 Figure 48. Wild poliovirus type 1 (WPV1) by genetic cluster and circulating vaccine-derived poliovirus type 2 (cVDPV2) by emergence, Nigeria, 2013 and 2014 to date* 2013 2014 WPV1 cVDPV2 Source: CDC *Data as of 20 August 2014 Page 53 GPEI Partner Status Report - 25 September 2014 Figure 49. WPV1 cases and environmental isolates by genetic cluster, Nigeria, 12 August 2013 to 11 August 2014* Source: CDC *Data as of 20 August 2014 CIRCULATING VDPV2 IN WEST AND CENTRAL AFRICA cVDPV2 emergence in Nigeria: The number of cVDPV2 cases associated with circulating Nigerian lineages (from Nigerian emergences) increased substantially during 2014. Seven cases were detected in two states; Kano (6 cases) and Borno (1 case). The last case detected corresponded to an AFP case in Kano with onset date 22 June 2014. From all AFP cases, 14% had less genetic linkage than expected with sensitive AFP surveillance. Environmental sampling detected 64 cVDPV2s in five states (Borno, Kaduna, Kano, Katsina, and Sokoto) from the Nigerian emergence group 2005-8, which has been circulating for more than nine years. Additionally, independent aVDPV2 emergences occurred in four states (cases in Kano and Federal Capital Territory, and environmental samples in Kano, Sokoto, and Kaduna) during 2014. Page 54 GPEI Partner Status Report - 25 September 2014 Figure 50. cVDPV2 in Nigeria and Niger by emergence, 12 August 2013 to 11 August 2014* Source: CDC * Data as of 20 August 2014 cVDPV2 emergence in Chad: VDPV2 emergence in Chad in 2012 affected Nigeria, Niger and Cameroon. During the reporting period, 17 new cases (five in 2013 and twelve in 2014) were detected in Nigeria (and one detected in Niger in 2014 representing a Nigerian child), corresponding to the emergence group A of the 2012 Chad cVDPV2 outbreak. Most cases were detected in Borno, in addition to cases in Adamawa and Kano states. The latest case had onset date of 21 June 2014. During 2014, sentinel environmental sites in Borno identified more than 30 samples with viruses genetically linked to the Chad cVDPV2 group A outbreak. The only other environmental site reporting viruses linked to this emergence was in Kano state. During the reporting period, there were no cases reported from Cameroon. One AFP case was reported in Niger with onset date 14 May 2014. Page 55 GPEI Partner Status Report - 25 September 2014 POLIOVIRUS SANCTUARIES AND RISK AREAS At the time of this report, Nigeria has two virus sanctuaries and one risk area: 1. North-Central Sanctuary (Kano, Katsina, Jigawa, and Kaduna) 2. Northeast Sanctuary (Borno and Yobe) 3. Northwest Risk Area (Sokoto and Zamfara) Although WPV cases have not been identified in Katsina and Kanduna since 2012, these states with Kano and Jigawa formed a common reservoir of linked WPV clusters until that time that often led to circulation in Bauchi state. The Northwest states of Sokoto and Zamfara do not appear to have circulating WPV; these states are now referred to as the Northwest Risk Area. NORTH-CENTRAL SANCTUARY Figure 51. WPV and cVDPV cases, North-Central Sanctuary, 3 September 2013 to 2 September 2014* Notes regarding Nigeria’s LQAS survey results (see next page). Decision rules of 0–3, 4–8, 9–19, and 20–60 for sample sizes of 60 in Nigeria provide a reasonable assessment of SIA quality at 90% (High Pass), 80% (Pass), and 60% (Low) thresholds (or Fail if below) for programmatic purposes under the assumption of moderate variability in cluster-level results. Source: WHO Data as of 9 September 2014 Page 56 GPEI Partner Status Report - 25 September 2014 Figure 52. WPV and cVDPV cases by week of onset and environmental surveillance results, North-Central Sanctuary (Kano, Katsina, Jigawa, and Kaduna), Nigeria, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Data not Available Figure 53. Proportion of LGAs with LQAS survey results by SIA, North-Central Sanctuary, Nigeria, Sept 2013 to Aug 2014 The October round was a combined measles OPV-measles campaign. Figure 54. Proportion of NPAFP cases 6 to 35 months, by OPV status, North-Central Sanctuary, Nigeria** Source: WHO **Data as of 9 September 2014 Page 57 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of LGAs meeting indicators 1 week pre-campaign North Central Sanctuary Percent of LGAs meeting indicators 3 days pre-campaign Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 # of LGAs participating 128 128 128 128 128 128 128 128 128 128 128 128 % of LGA task force met 79 78 95 99 100 99 98 99 100 100 100 100 % of LGA counterpart funding released 34 34 35 34 34 0 71 84 88 66 82 0 State task force met yes yes yes yes no yes yes yes yes State counterpart funding released no no no no no no yes no no Jigawa Kano State task force met yes yes yes yes yes yes yes yes yes yes State counterpart funding released no yes yes yes no yes yes yes yes yes Kaduna State task force met No yes no yes yes yes yes yes yes yes yes State counterpart funding released No no no no no no yes yes yes yes yes State task force met yes yes yes yes yes yes yes State counterpart funding released no no no no yes yes yes Katsina Abbreviations: LGA=Local Government Area No campaign Source: Nigeria Polio Campaign Dashboard, WHO-Nigeria No data ------------------------------------------------------------------------------------------------------------------------- NORTHEAST SANCTUARY Figure 55. WPV and cVDPV cases, Northeast Sanctuary, 3 September 2013 to 2 September 2014* Source: WHO *Data as of 9 September 2014 Page 58 Source: WHO **Data as of 9 September 2014 GPEI Partner Status Report - 25 September 2014 Figure 56. WPV and cVDPV cases by week of onset and environmental surveillance results, Northeast Sanctuary (Borno and Yobe), Nigeria, 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Data not Available Figure 57. Proportion of LGAs with LQAS survey results by SIA, Northeast Sanctuary, Nigeria, Sept 2013 to Aug 2014 The October round was a combined measles OPV-measles campaign. Figure 58. Proportion of NPAFP cases 6 to 35 months, by OPV status, Northeast Sanctuary, Nigeria** Source: WHO **Data as of 2 September 2014 Page 59 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of LGAs meeting indicators 1 week pre-campaign Northeast Sanctuary Percent of LGAs meeting indicators 3 days pre-campaign Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 # of LGAs participating 128 44 44 44 44 44 44 44 44 44 44 44 44 % of LGA task force met 79 61 39 98 59 39 61 39 39 57 59 39 % of LGA counterpart funding released 34 0 59 98 59 95 98 39 59 98 98 95 State task force met no yes yes no yes yes yes yes State counterpart funding released no yes yes yes yes yes yes yes State task force met yes yes yes yes yes yes yes State counterpart funding released no no no yes yes yes yes Borno Yobe Abbreviations: LGA=Local Government Area No campaign Source: Nigeria Polio Campaign Dashboard, WHO-Nigeria No data _________________________________________________________________________________ NORTHWEST RISK AREA Figure 59. WPV and cVDPV2 cases, Northwest Risk Area, 3 September 2013 to 2 September 2014* Source: WHO Data as of 9 September 2014 Page 60 GPEI Partner Status Report - 25 September 2014 Figure 60. WPV and cVDPV cases by week of onset and environmental surveillance results, Northwest Risk Area (Sokoto and Zamfara), Nigeria 3 Sept 2013 to 2 Sept 2014* Source: CDC *Data as of 9 September 2014 Data not Available Figure 61. Proportion of LGAs with LQAS survey results by SIA, Northwest Risk Area, Nigeria, Sept 2013 to Aug 2014 The October round was a combined measles OPV-measles campaign. Figure 62. Proportion of NPAFP cases 6 to 35 months, by OPV status, Northwest Risk Area, Nigeria** Source: WHO **Data as of 2 September 2014 Page 61 GPEI Partner Status Report - 25 September 2014 OWNERSHIP Percent of LGAs meeting indicators 1 week pre-campaign Northwest Risk Area Percent of LGAs meeting indicators 3 days pre-campaign Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 Jan '14 Mar '14 Apr '14 May '14 Jun '14 Jul '14 Aug '14 # of LGAs participating 37 37 37 37 37 37 37 37 37 37 37 37 % of LGA task force met 65 62 100 41 100 100 100 100 100 100 100 100 % of LGA counterpart funding released 49 14 0 3 0 3 65 22 19 0 65 3 Sokoto State task force met yes no no yes yes yes yes State counterpart funding released no no no no no yes yes Zamfara State task force met yes no yes yes yes yes yes State counterpart funding released no no no no no yes no Abbreviations: LGA=Local Government Area Source: Nigeria Polio Campaign Dashboard, WHO-Nigeria No campaign No data ------------------------------------------------------------------------------------------------------------------------- COMMUNICATION AND SOCIAL MOBILIZATION Stopping transmission in Nigeria is the condition for a polio-free Africa, yet the Nigeria programme also has to keep an eye on its neighboring countries. Re-importation from the ongoing Central Africa Outbreak remains a real threat. If Ebola spreads outside of Lagos and Rivers States, especially to northern Nigeria, this would present a new and significant threat as well. Harvard polling data shows a difference between levels of knowledge, trust and exposure to misinformation about the vaccine in Borno, as compared to high-risk areas elsewhere in Nigeria. In Borno, 37% of parents thought paralysis from polio was curable (vs. 24% in other high-risk areas polled in Nigeria). The percentage of parents in Borno who were not aware that OPV must be taken every time it’s offered to maximize protection against the disease was 35% (versus 29% elsewhere in Nigeria). Obstacles to trust are especially pronounced in Borno where 48% of parents said they’d heard negative rumors about the vaccine. However, only 4% of these believed the rumors they’d heard. But these rumors are likely to only be a visible symptom indicating more important underlying issues and a negative community sentiment/discourse about OPV and the polio programme. Only 85% of parents in Borno said they gave their children vaccine the last time they saw vaccinators, the lowest rate cited by parents anywhere in the world. Less than 48% of Borno parents said they trust the vaccinators “a great deal,” while elsewhere in Nigeria the rate was 70%. VOLUNTEER COMMUNITY MOBILIZERS Nigeria’s VCM network is now the largest social mobilization network in the world. In the last quarter, the number of VCMs rose by more than 1,200 mobilizers alone. In addition to this vast community network of nearly 10,000 at settlement level, a management layer of 1,000 supervisors are in place at ward and district levels. Outside the formal network, more than 224 religious focal points facilitate access to more than 17,000 religious leaders and teachers, traditional leaders are actively engaged and 1,400 polio survivors help maintain a healthy level of risk perception within their local communities, putting a human face to the poliovirus. Nigeria’s mobilizers are increasingly active in generally inaccessible areas and can have a huge impact on community acceptance there. Between UNICEF and CORE, more than 800 are already working in Borno and Yobe. The VCMs are even more effective when they’re trained to offer broader skills in other key areas of Page 62 GPEI Partner Status Report - 25 September 2014 child and maternal health. These skills can make them indispensable advisors in communities where organized health care is weak or non-existent. In accessible and inaccessible areas alike, VCMs show communities that polio drops are part of an overall approach to caring for the whole child. This entry point has helped meet community demands for broader health services and has increased acceptance rates substantially. Nigeria has had a consistently declining refusal rate for the past two years, and now has the lowest rate globally according to Independent Monitoring data. Beyond refusals, Nigeria’s results in reducing missed children are impressive, particularly in Kano. In Kano— where nearly half the VCM network is placed—the community has been an important contributor to success. BUILDING A BIGGER AND BETTER WORKFORCE As the Nigerian programme has scaled up over the years, thousands of frontline workers, social mobilizers and vaccinators alike have had different levels and quality of training. The rapid scale up, turnover of staff, responsibility and size of these workforces mean Nigeria must remain vigilant to ensure that workers follow standards of excellence, particularly as the programme continues to innovate and introduce new approaches in these critical few months. Figure 63. Although health camps have been implemented with varying scale and scope over the last year, frontline workers had not received formalized training on integrated health. In July, Nigeria was the first country to test the newly developed global training curriculum for integrated health. A two-day training of trainers was conducted in Kaduna and Katsina States, attended by VCM staff and nearly 150 State Health Coordinators. The training consisted of a basic integrated health package on primary health care interventions focused on maternal, newborn, and child health. Content covered IPC applied to the introduction of IPV, water/sanitation/hygiene (WASH), malaria, pneumonia, diarrheal diseases, and a basic human rights module. More than 900 participants were trained in this first phase. Page 63 GPEI Partner Status Report - 25 September 2014 PERFORMANCE MANAGEMENT To adequately identify high and low performers, Nigeria is implementing a revamped performance evaluation system, which includes data collection against the global performance dashboard, and dissemination through a data platform that will integrate all data sources for the programme into one database for more cohesive, sophisticated analysis. As part of this system, UNICEF will collect programme data with GPS coordinates for faster mapping of performance and skills together. A monthly performance management dashboard will be used to more closely monitor performance of staff. The IVR system will be used as an additional way of getting direct feedback from supervisees on how supervision is going. This system initiates a 360° evaluation system for the first time as well, instilling accountability for good management in addition to good performance on the ground. While this more systematic approach is being implemented, the programme has been using a simple performance management system that tracks performance based on a ‘three strikes’ system. To date, 447 VCMs, 66 ward supervisors, 65 polio survivors, nine LGA consultants and four religious focal points have been terminated for poor performance. Conversely four Ward Supervisors were promoted to LGA consultants for good performance, as well as four LGA consultants to cluster consultants, and four cluster consultants to state leads. Figure 64. Number of children vaccinated in specific demand-creation In an effort to ensure proper team exercises, 10 high-risk states, Nigeria January to August 2014 selection, partner staff have assumed oversight of the ward level team selection committees. Partner staff at local levels participate in the committees to ensure that frontline workers are vetted for profile and skillset. The partnership is responsible for monitoring and reviewing the performance of any frontline worker, irrespective of which agency has hired them. FOCUS ON THE HARD TO REACH Through Nigeria’s Hard to Reach mobile outreach project, 3200 underserved villages receive the polio vaccine four times a year, along with other health- and lifesaving interventions. Routine immunization is provided, together with free medicine to fight malaria and diarrhea. Adults are also treated, especially pregnant mothers. These temporary services are welcomed enthusiastically by communities within the context of a weak healthcare system. So far, attendance has been exceptional. This year, more than 414,000 people in Kano alone will benefit from health camps offering vital primary services during polio campaigns. Page 64 GPEI Partner Status Report - 25 September 2014 In between campaigns, the VCMs record newborns in their settlements, attend the naming ceremony of the baby (usually on the 7th day after birth), and give the first dose of OPV for 90% of these children. Today, on average, in the 10,000 settlements covered by the VCM Network, 3,100 births are tracked every week, 2,700 children are given the first dose of OPV, and 2,800 children are linked to health facilities for routine immunization services. More than 100,000 newborns across the country have been tracked this way since the data started flowing in 34 weeks ago. In Kano, nearly 80% of expected newborns are recorded and vaccinated at birth. COMMUNITY-BASED MANAGEMENT OF ACUTE MALNUTRITION (CMAM) Community Mobilizers are also trained to identify signs of malnutrition in children and refer them to CMAM centers to receive proper treatment. Polio drops are in turn administered at these centers, reaching children whose immunity is especially low. The CMAM initiative, like the health camps, serves a twofold aim. It simultaneously helps reach hard-toreach children, and allows workers to take tangible action on behalf of the whole child—thereby building trust. Figure 65. Numbers of newborns registered and vaccinated by VCMs, Kano, May to August 2014 Figure 66. Number of children vaccinated at CMAM centers and number receiving the first OPV dose, 10 high-risk states, Nigeria, January to August 2014 Today a total of 575 CMAM centers are operational in the 11 high-risk states of Northern Nigeria, which in many cases also provide therapeutic food and counselling, vitamins, deworming, routine vaccines and OPV in addition to therapeutic food. Scale-up is in progress, with particular focus on Borno state. Page 65 GPEI Partner Status Report - 25 September 2014 The CMAM is also reaching children who might otherwise be completely missed. Among approximately 5,000 children who were vaccinated at CMAM centers in August, 10% received polio vaccine for the first time (Figure 66). PROGRAMME INFORMATION ACCESSIBILITY AND SECURITY The security/ humanitarian situation in the Northeast Nigeria sanctuary (Borno and Yobe States and northern parts of Adamawa) remains critical as fighting has intensified between the Nigerian military and insurgents. The Nigerian Governmentimposed State of Emergency, introduced in May 2013 and due to expire in May 2014, likely will remain in force for the foreseeable future. Insurgents continue to attack strategic towns. Other insurgency targets include political and religious figures. Continued instances of reprisal attacks against the civilian population, including kidnapping, have been reported. Armed conflict in the southern and eastern areas of Borno, in southern Yobe, and more recently in Adamawa state has led to increased rural to urban movement of IDPs in these states, and forced others to seek refuge in Cameroon and Chad. Figure 67. Insecurity Levels in Nigeria, August 2014 Figure 68. Inaccessible areas, WPV1 cases, and the estimated number of children affected during the August 2014 SIA—Northeast Sanctuary, Nigeria Other major security incidents outside of this region may also be attributed to the insurgency as it seeks to expand its operations. For example, since the end of April 2014, a number of attacks have occurred, attributed to insurgent activity outside of Borno and Yobe. Page 66 GPEI Partner Status Report - 25 September 2014 Figure 69. Inaccessible Settlements in Borno and Yobe Provinces, Nigeria, August 2014 In addition, there appears to be an ever-evolving change to tactics used by the insurgents. For example, on 9 June, a female suicide bomber, the first in Nigeria’s history, detonated explosives at a military barracks in Gombe, killing one soldier and herself. In July, bombs exploded in Kaduna after the Ramadan sermon by a prominent sheikh, killing more than 30 people. Additionally, Boko Haram appears to have adopted a kidnapping strategy and took hostage a German NGO worker in Adamawa on 16 July 2014. This increases the perception of fear for frontline workers and implementing partners to deliver the programme. Although the insurgency’s recent operations in the Middle Belt and Lagos are of immediate concern, the longer-term threat for Nigeria remains firmly in the Northeast. Since April, insurgents have been sealing Borno’s road and bridge connections to Cameroon, Adamawa and Yobe and taking towns to the south and north east of Maiduguri. Because of the deteriorating security situation in the Northeast, the UN Security Management Team has continued to limit UN staff movement in Yobe and Borno, preventing the GPEI’s ability to fully monitor eradication efforts. Seven out of the 17 LGAs in Yobe remain inaccessible to UN Staff whereas in Borno, only two out of 29 LGAs remain totally accessible to UN Staff. Other security threats remain acts of criminality, communal violence in the Middle Belt and Northwest geopolitical zone of the country, as well as politicallymotivated violence in the central and southern areas. Page 67 GPEI Partner Status Report - 25 September 2014 INCIDENTS INVOLVING POLIO PERSONNEL During August 2014, in isolated incidents a polio worker was beaten during an IPD in Kano State, and another was a victim of armed robbery in Sumaila LGA, also in Kano. These incidents are not believed to be selected targeting of polio personnel, but rather as a result of local tension and opportunity crime, respectively. Although the motivations for the attack are unclear, in June, suspected Boko Haram insurgents dressed in military uniform were reported to have attacked a health camp team at Sasawa village in Damaturu, Yobe. The perpetrators seized and destroyed all the vaccines and other equipment. Although the programme in Nigeria continues to reach more children overall, the lack of accessibility in Borno and Yobe continues to hamper polio immunization. Since April 2014 the number of missed children due to inaccessibility has risen from 0.4% to 1.6% in Yobe and from 16% to 23% in Borno. HUMAN RESOURCES Location (sanctuary or risk area) Northwest (Sokoto and Zamfara) Total number of vaccination teams Number (%) of Number (%) of Salary per Number of current vaccination teams with a vaccination teams vaccinator / day GPEI staff female member with a local member Number of additional GPEI staff needed (if surge is planned) 4,884 4,884 (100%) 4,884 (100%) $4.32 307 8 30,328 30,328 (100%) 30,328 (100%) $4.32 1089 16 3,554 3,416 (96%) 3,554 (100%) $4.32 346 3 North central (Kano, Katsina, Jigawa, and Kaduna) Northeast (Borno and Yobe) Source: WHO ROTARY INTERNATIONAL’S WORK IN NIGERIA Rotarians in Nigeria have focused their efforts on the following social mobilization activities: • • • • • • Providing ‘plus’ items such as soap that are used as incentives during “immunization plus days” Engaging traditional leaders in the supervision of IPDs and resolution of non-compliance Addressing broader health needs through the provision of first aid kits for Almajiri and Islamiya schools Providing 21,000 doses of medicine used during health camps Delivering ‘plus’ items for IPV Introduction in Borno state as well as for use during SIAs as above Developing a newsletter, website, and media pages to help raise awareness and highlight the role of Rotary’s PolioPlus Ambassadors Page 68 GPEI Partner Status Report - 25 September 2014 PERFORMANCE INDICATORS IMMUNIZATION AND SURVEILLANCE Figure 70. Six-month standard immunization indicators among children aged 6-35 months with AFP and annualized surveillance indicators by state, Nigeria, February 2013 to August 2014 Source: CDC Page 69 GPEI Partner Status Report - 25 September 2014 GPEI POLIO ERADICATION AND ENDGAME STRATEGIC PLAN 2013–2018, NIGERIA STRATEGIC! PLAN! OBJECTIVE! OUTCOME!INDICATORS! (2013)! RESULTS! All!wild!poliovirus!transmission! !The!most!recent!WPV!! stopped!by!the!end!of!2014! Poliovirus! Detection!and! Interruption:! Complete! the! interruption! of!wild! poliovirus! transmission! globally!and! more! rapidly!detect! and!interrupt! any!new! outbreaks!due! to!vaccineM derived! polioviruses! ! NA*!! All!new!cVDPV!outbreaks! stopped!within!120!days! Circulation!of!cVDPV!imported!from!Chad,!as! evidenced!by!cases!and!environmental! isolation,!was!not!stopped!within!120!days!of! confirmation.! OUTPUT!INDICATORS!(2013)! !! Achieve!and!maintain!an! NPAFP!rate!of!›!2/100,000! children!<15!years!of!age!in!all! states/provinces!of!highMrisk! countries!and!maintain!an! NPAFP!rate!of!›!2/100,000!in! all!states/provinces!! From!16!August!2013!to!16!August!2014,!the! national!NPAFP!rate!was!11.8/100,000,!an! absolute!2.1%!increase!from!the!previous!year.! One!hundred!percent!of!provinces!have!been! maintaining!NPAFP!>2/100,000!since!the!last!2! rolling!years.! Met! Achieve!and!maintain! adequate!stool!sample! collection!in!80%!of!cases!in!all! states/!provinces!! During!the!last!12!months,!98%!of!AFP!cases! nationally!had!an!adequate!stool!specimen.! This!is!an!absolute!2%!increase!from!last!rolling! year.!All!provinces!in!Nigeria!have!been! maintaining!adequate!stool!collection!in!>80%! of!AFP!cases!since!the!last!2!rolling!years.! Met! LQAS!passed!at!80%!threshold! in!all!highMrisk!areas! In!the!last!12!months!in!the!85!highest!risk! LGAs,!>80%!have!been!achieving!the!80%! threshold,!and!since!May,!>90%!have.! Establish!full!safety!and! security!framework!! All!current!cVDPV!outbreaks! stopped!by!endM2013! * STATUS! A!UN!security!management!and!enhancement! plan!has!been!developed!and!funded.!The! national!programme!has!developed!a!specific! operational!plan!with!innovative!strategies!to! vaccinate!children!in!highly!insecure!LGAs!of! Borno.!An!Emergency!Operations!Center!has! been!established!in!Borno.! There!have!been!2014!environmental!isolations! of!indigenous!strain!from!emergence!in!2005! and!a!recent!case;!imported!Chad!A!emergent! strain!continued!circulation!into!2014.!Virologic! evidence!indicates!ongoing!surveillance!gaps.! Not!met!! !! Not!Met!in!2013! Met!in!2014! Established!! Not!Met! * Not Applicable Page 70 GPEI Partner Status Report - 25 September 2014 SYNOPSIS • Epidemiology: Only six WPV1 cases have been reported so far in 2014. No WPV cases have been reported in the Northwest sanctuary for two years and none in the Northeast for five months. WPV1 transmission may be limited to a single zone comprised of southern Kano State and adjoining areas of Kaduna and Bauchi States. WPV3 has not been detected since 10 November 2012. cVDPV cases have increased in both Kano and Borno, and environmental sampling has detected cVDPVs across most of the north. • Immunization: LQAS data continue to show improvement. Since May, more than 90% of high-risk LGAs have achieved coverage at the ≥80% level. In June and August, IPV was used for the first time in SIAs in Nigeria, covering 1.7 million children less than 5 years old in all of Borno and selected areas of Yobe. • Security: Insecurity continues to limit access in Borno and Yobe States, although the programme’s data show improvement in access through March, with a larger number of children able to participate in SIAs until some regression in access during later SIAs. The overall security situation does appear to be deteriorating in the Northeast and insurgent groups reportedly holding key geographic areas particularly south of the Borno state capital hampers the ability to deliver programme elements safely and securely. • Surveillance: AFP surveillance performance indicators have steadily improved in Nigeria in recent years, with the national NPAFP rate now exceeding 13 per 100,000 children < 15 years of age per year and a national stool adequacy proportion of 97%. In Both Borno and Yobe, AFP reporting rates are increased over last year, to 14.7 per 100,000 children <15 years per year in Borno and 12.4 per 100,000 children <15 years per year in Yobe, and stool adequacy proportions exceed 98%. • Ownership: There is strong political support for polio eradication, but it needs to be sustained and intensified to drive the program to a successful conclusion. The Presidential Task Force on Polio Eradication has only met once in more than a year, and tracking the ‘Abuja Commitments’ shows a decline in the level of participation of state Executive Governors. Tracking data indicate that Local Government Area Chairmen are failing to maintain strong overview over immunization activities, with low participation rates in ‘evening review meetings’ during polio campaigns. • Community Demand: Independent monitoring data continue to show relatively low rates of vaccine refusal in Nigeria. However, anecdotal reports from southern Kano State suggest that vaccine refusal may be more common than suggested by these data, or masked by the number of children reported as ‘absent’ when vaccinators visit the home. Three of the five cases reported in Kano this year were in families that refused to allow their children to be vaccinated. Page 71 GPEI Partner Status Report - 25 September 2014 NON-ENDEMIC COUNTRIES HORN OF AFRICA OUTBREAK Figure 71. WPV cases by week of onset in the Horn of Africa, 2013–2014 to date* Source: CDC *Data as of 9 Sept 2014 The WPV1 outbreak in the HoA started in April 2013. The first case was identified in Banadir (Mogadishu) Somalia in May 2013 with subsequent cases identified in Kenya and Ethiopia. The last reported case in Kenya had onset on 14 July 2013. As of 9 September 2014, the most recent WPV1 case linked to this outbreak in the sub-region occurred in Somalia on 11 August 2014, >12 months after confirmation of the first case of the HoA outbreak. Figure 72. WPV1 and cVDPV Cases in the Horn of Africa, 2013-2014 to date*. Source: WHO *Data as of 9 September 2014 Among the three countries, time from outbreak confirmation to the onset of the latest case exceeded six months only in Somalia. In 2013, the outbreak accounted for 54% of the polio cases globally. In addition to the polio outbreak during 2013–2014, HoA countries have been affected by measles outbreaks, armed Page 72 GPEI Partner Status Report - 25 September 2014 conflict in the Republic of South Sudan, which caused the rapid migration of South Sudanese into Kenya and Ethiopia, and ongoing African Union military activities in Somalia against Al Shabaab militants which result in fluctuations in areas of accessibility, particularly in South Central Somalia. SOMALIA The outbreak was confirmed on 9 May 2013 when WPV1 was identified from a case with an onset of 18 April. So far, Somalia has had a total of 199 confirmed WPV1 cases (194 cases in 2013 and five cases in 2014). The most recent case was Figure 73. WPV cases and inaccessible children in Somalia in the from Hobyo district, Mudug August 2014 SIA Region (onset 11 August 2014). Four cases reported earlier in 2014 were from nearby Jariban district in Mudug region. No new WPV cases have been reported from Banadir region, the epicenter of the Somalia outbreak, since 19 July 2013. Among the 199 cases, 88% were among children aged <5 years and two (1%) cases were aged >15 years (27 and 29 years of age). During 2013–2014, 55 cases (28%) were in accessible areas, 50 cases (26%) were in inaccessible areas, 48 (24%) were in partially accessible areas, and 46 (23%) were in accessible areas with security challenges. During 2014 to date, the overall NPAFP rate was 7.8 per 100,000 children <15 years Source: WHO Data as of 9 September 2014 of age per year and stool adequacy was 96.5%. Five cases (aged 18 months to 29 years) have been detected in 2014, all in the Mudug Region of Somaliland in two bordering districts: (Jariban, 4 cases, and Hobyo, 1 case). All of the cases have occurred in pastoralist families residing in hamlets outside larger settlements and were missed during previous SIAs during 2013 and 2014. Of these cases, none had received an SIA dose of OPV and only one had received a single dose through the EPI program, in a neighboring city. Outbreak response to the four May/June cases included three SIAs during June-August targeting the Mudug region and all of Puntland. Three additional SIAs will be conducted during September-October (entire Mudug region, accessible parts of Galgadud and two districts of Bari [Eyl and Burtinle]) in response to the more recent cases. The programme is currently taking steps to identify pastoralist communities and to incorporate them into SIAs through means of improved microplanning, enhanced mapping through use of satellite images, and outreach to community leaders and elders. Page 73 GPEI Partner Status Report - 25 September 2014 In 2013, 10 rounds of SIAs were administered, some targeting all age groups or children up to 10 years of age and some conducted at short intervals. In 2014 12 SIA rounds have been implemented to date targeting children up to 5 years of age (seven rounds), up to 10 years of age (two rounds), and all groups (one round). In addition, four SIADs are implemented in each newly accessible district of the South Central Zone. In the newly accessible districts, to date, four rounds have been conducted in Huddur and Mahas districts, respectively, with the last round occurring in July. SIAs in Bhurdubu are currently underway, and rounds in Wajid district are awaiting availability of cold chain supplies and vaccine. Efforts to access children in inaccessible areas are ongoing with involvement of local NGOs and low profile vaccinations. District accessibility is closely monitored and SIAs are implemented within one week of gaining access. Efforts to expand independent monitoring to all accessible districts are ongoing with involvement of local NGOs and professional groups. Challenges exist in identifying qualified independent monitors in some accessible districts. ETHIOPIA The most recently reported case occurred in the Somali Region of Ethiopia on 5 January 2014. Six SIAs have been conducted thus far in 2014 and two NIDs are scheduled later in the year. Suboptimal surveillance in the Dollo Zone of the Somali Region makes it uncertain that transmission has been interrupted. Microplanning needs to address the nomad/pastoralist communities that are often missed in SIAs. COMMUNICATION AND SOCIAL MOBILIZATION Independent monitoring data in the HoA (where collected) confirms levels of polio campaign awareness between 85% to more than 90% across the region, especially in the areas where significant investments in social mobilization have been made. Yet, once disaggregated by subdivisions, a number of geographical areas of concern exist, even within the “green” districts. This includes the Somali region in the Dollo zone of Ethiopia, Dhusamareb, Hargeysa and Baidoa in Somalia, and almost the whole Coastal province of Kenya. Figure 74. Polio Campaign Awareness by Province/State, Horn of Africa Although refusals across the region overall remain less than 1% of targeted children, this acceptance of vaccination should not be taken for granted; rather, this positive perception of polio vaccination must continue to be maintained until all outbreak transmission is finished. Page 74 GPEI Partner Status Report - 25 September 2014 MUDUG REGION The response to the recent outbreak in Mudug, Somalia has been supported with significant social mobilization and communication efforts. Independent Monitoring data for Mudug region and Harvard Opinion Research Poll for Puntland provided proxy information that campaign awareness in this region varied greatly from more than 90% to 41% in localized areas. A joint investigation into the affected community in Jariban showed there was a positive attitude towards immunization and health services, but a gap in services. Media coverage here is extremely low, with a short-wave BBC broadcast serving as the main source of information for communities. Because of limited mass communication channels across this region, social mobilization efforts have been significantly enhanced, deploying over 100 social mobilizers in Mudug and more than 1,300 in Puntland alone. Public loudspeakers mounted on vehicles are now a main source of campaign announcement, with five new FM radio stations airing 720 spots before each campaign. Islamic influencers and clan elders have been fully mobilized to provide campaign support and entry points to madrassas, duqsies, and mosques. Communication messages have been changed from health information to risk communication—more urgent and immediate, with clear calls for immediate action. The parents of a polio-affected child have given a testimonial that helps explain the proximity and personal risk for polio to the community. These strategies have contributed to wide acceptance of polio vaccine during the last three rounds. STRATEGIES TO IMPROVE SIA QUALITY, ACCESS AND REACH POPULATIONS ON THE MOVE The main challenge to reaching all children in the Mudug region, similar to the affected areas of the Somali Region of Ethiopia, is the pastoral lifestyle of the local communities. Many young children live in small satellite settlements away from the main village. The coverage of children in these satellite settlements has been inadequate. To overcome this challenge, the program is taking a number of steps that include deployment of additional human resources for planning and monitoring and ensuring completeness of microplans to cover all settlements. A number of strategies are being applied to assure full microplan coverage which includes close coordination with village and tribal elders on listing all settlements, on the ground and aerial validation of settlements and triangulation of these data with high resolution satellite imaging. While Jariban district was accessible yet hard to reach, 27 districts in South-Central Zone remain partially or completely inaccessible. GPEI partners in the HoA are expanding their capacity to: a) understand the reasons why particular regions/districts/specific areas present access challenge and what specific threats exist at the most local levels, b) map influencers who control communities, c) understand who is opposed to the programme and why, and d) come up with mitigation measures that are best suited to reduce the level of residual risk and possibly improve access. Since May, access has been gained in four new districts in South Central, opening up access to 25,000 children. The use of Independent Monitoring data for action has been steadily improving in the region. All countries except Somalia where this process is still on-going, have adopted analysis of missed children for the category “child absent”. Now countries are able to collect, analyze and use these data for action. The most significant reasons children are missed when they are absent are because they are in pastures, market places, or schools (varied by countries). Recognizing the need to focus on mobile populations, including pastoralists, GPEI partners in the HoA have begun to better understand these complex groups, their movement patterns and design flexible country-based Page 75 GPEI Partner Status Report - 25 September 2014 strategies and action plans to reach them more consistently. Thorough engagement with the key stakeholders in the migration has resulted in action plans and practical strategies. Cross-border communication platforms for the Somali population have been engaged to support SIAs, including BBC Somali Service, Voice of America Somalia, and Star FM Kenya. All of these stations broadcast across the Somali populated areas of Somalia, Ethiopia, and Kenya. Evaluation of the BBC Somali service project and anecdotal evidence from the field demonstrate importance of these media channels to reach farflung populations. CENTRAL AFRICA OUTBREAK Figure 75. WPV1 and cVDPV Cases in the Central Africa, 2013–2014 to date* Source: WHO *Data as of 9 September 2014 Figure 76. Population movements within and from CAR as of 9 September 2014, The WPV1 outbreak in 2014the Central African Republic Central Africa was discovered in October 2013 in Cameroon with subsequent spread to Equatorial Guinea. To date, there have been 14 WPV1 cases (nine in Cameroon, five in Equatorial Guinea). As of 9 September 2014, the most recent WPV1 case this outbreak occurred in Cameroon in a refugee from the Central African Republic (CAR) with onset on 9 July 2014. The most Page 76 GPEI Partner Status Report - 25 September 2014 recent case in Equatorial Guinea had onset on 3 May 2014. The ongoing outbreak in Cameroon and Equatorial Guinea puts CAR, Democratic Republic of the Congo (DRC), Congo and Gabon at risk because of population movement in the area and low population immunity. More than 500,000 people travel in and out of Cameroon alone each year. This intense population movement (social, commercial, refugees, IDPs, etc.), coupled with poor AFP surveillance makes the possibility of undetected transmission in both Gabon and CAR quite high. The complex humanitarian crisis in CAR also increases the risk of polio transmission in the region. Gabon and Congo conducted nationwide campaigns in June/July 2014, and the CAR conducted campaigns in the west along the borders with Cameroon and Chad in August and September. A synchronized campaign was to be held 18-23 September in Cameroon, CAR, Congo, DRC, Equatorial Guinea and Gabon. A regional outbreak coordinator for Central Africa was appointed in August. Figure 77. WPV cases by week of onset in Central Africa, 2013-2014 to date* CAMEROON *Data as of 9 September 2014 Since October 2013, nine WPV1 cases have been reported from West, North West, Centre, Adamaoua and East regions, with onset of paralysis ranging from 1 October 2013 to 9 July 2014. The latest case was in a child who was a refugee from the CAR who had been vaccinated twice during campaigns in the refugee camp. The genetic sequencing of the more recent WPV1 strain suggests it has been circulating undetected in Cameroon for about one year. Thus far in 2014, Cameroon has conducted seven nationwide immunization campaigns. SIA quality by LQAS data has improved slightly in the last two campaigns compared with campaigns earlier in the year. In addition to the paucity of national human resources and high level attention allocated to the outbreak response, the main reasons for sub-optimal coverage initially related to poor quality of microplans. This was addressed to a large extent through training and updating of microplans in mid-2014. Low visibility of campaigns and low awareness levels among parents about the campaigns remains a significant reason for gaps in coverage. The second three-month outbreak response assessment has been conducted during 16-25 September. Surveillance training at the regional level was conducted in August and is being rolled out to the districts in September. A full-time country outbreak coordinator was identified in July 2014. EQUATORIAL GUINEA As of 9 September 2014, five WPV1 cases have been confirmed, the most recent with onset 3 May 2014. Response to the outbreak has been challenging. At the beginning of the outbreak, surveillance was poor, with only 2 AFP cases having been reported in the prior 5 years, and the country had been five years without an SIA. Equatorial Guinea conducted national campaigns in April, May, August, and September. These Page 77 GPEI Partner Status Report - 25 September 2014 campaigns have been of insufficient quality. AFP surveillance remains poor; training was conducted in August for 100 persons who will begin surveillance soon. Although cases have been detected through searches during SIAs, a rapid national polio case search in health facilities and communities that was recommended by the Central Africa Technical Advisory Group in July has not yet been implemented. Government commitment has been variable. While the Ministry of Health has been engaged and committed, the upper levels of government have not been. The government so far has offered to fund only the most recent SIA (the 5th outbreak response SIA) and the November SIA, but not the two in between. The government has also been unresponsive to the partnership’s concerns about the difficulty of obtaining necessary visas. This latter problem has hampered efforts to bring in outside experts to assist in the response. COMMUNICATION AND SOCIAL MOBILIZATION Challenges in identifying and deploying staff to Central Africa—compounded now by the Ebola crisis—in addition to overstretched GPEI resources continue to affect the response in Central Africa. Government commitment, delayed financial flows and limited national oversight underline more systemic, underlying challenges. MIDDLE EAST OUTBREAK SYRIA On 28 October 2013, the Minister of Health of the Syrian Arab Republic announced that after 15 years of absence, polio had returned to the Middle East. Thirteen cases due to WPV1 were confirmed from Deir Al Zour province in Syria. Genetic sequencing indicates that the virus, originating from Pakistan, likely had been circulating in Syria for nearly a year before detection (and is linked to WPV1 detected in environmental samples collected in Egypt in December 2012, and in Israel, the West Bank and Gaza during February 2013–March 2014). Since that time, as of 31 August 2014, a total of 36 cases have been confirmed in Syria, with the most recently reported confirmed case of polio occurring on 21 January 2014. Syria, being the primary outbreak zone, has conducted eight NIDs to date with the most recent one in June 2014 and one SNID in August 2014. During the June NID, estimated coverage, determined by postcampaign monitoring, was 89%. The first Figure 78. WPV cases in Syria and Iraq, 2013-2014 to date* Source: WHO Source: WHO *Data as of 9 September 2014 *Data as of 9 September 2014 Page 78 GPEI Partner Status Report - 25 September 2014 mass vaccination campaign using tOPV was launched by the Ministry of Health, Syria on 24 October 2013, within five days of WHO’s polio alert. An estimated 2.4 million children were vaccinated during the campaign that extended for four weeks because of conflict and logistic challenges. The Syrian government fast-tracked the registration of bOPV in November 2013 and it has been used in all subsequent SIAs. No WPV cases have been detected in Syria since the 2014 case with 21 January onset. During 2014 to date, the annualized NPAFP rate is 3.0 per 100,000 children < 15 years of age per year and the proportion of AFP cases with adequate specimens is 90%. Figure 79. WPV and AFP cases by week of onset in Syria (n=36) and Iraq (n=2, WPV), 2013–2014 to date* Source: GPEI Eastern Mediterranean Region/MENA *Data as of 8 September 2014 IRAQ Iraq confirmed the first WPV1 case since 2000 in a 6-month old, intentionally unvaccinated child in Baghdad who had onset of paralysis on 10 February 2014. In April 2014, the second case was reported in Baghdad. Genetic sequencing indicates the viruses are most closely related to virus detected in December 2013 in Hasakeh, Syrian Arab Republic. In August 2014, Iraq conducted its tenth SIA since October 2013, most of which used tOPV; the last two SIAs in June and August used bOPV. During the August NID, 1,872,684 children under 5years of age were vaccinated with post-campaign monitoring coverage of 92 %; 142,448 were children in IDPs camps. Subsequent campaigns will use bOPV. The majority of zero-dose NPAFP cases reported during 2013 and 2014 were from Baghdad. During 2014, the annualized NPAFP rate was 4.2/100,000 children <15 years of age and sample adequacy proportion was 89% compared with an NPAFP rate of 3.1/100,000 children and stool adequacy of 84% during 2013. Two provinces have NPAFP rates below 2/100,000 children per year. MIDDLE EAST OUTBREAK RESPONSE Since WPV cases were first found in Syria, the outbreak has been considered to be regional and the outbreak response has been targeted accordingly. During November 2013–August 2014, 35 SIAs have been carried out in seven countries. The regional outbreak response is currently being coordinated out of Amman, Jordan. The most recent review of the response was conducted in early September. In the 11 Page 79 GPEI Partner Status Report - 25 September 2014 months since Syria’s polio outbreak began, the programme has reached more than 25 million children with the polio vaccine in the region’s largest-ever mass immunization campaign. During the most recent campaigns, the vast majority of children across the Middle East were reached, with estimated coverage more than 90% in Syria, and Iraq. Jordan and Lebanon lag behind, with estimated 88% and 78% coverage respectively. There is need to focus on further improvements in the quality of the campaigns guided by independent post-campaign monitoring; post-campaign monitoring has been conducted more regularly since March 2014, particularly in Syria and Iraq. The March review also showed the need to strengthen communication to raise awareness and especially the importance of taking polio vaccine each time it is offered during the multiple campaigns planned, and to address surveillance gaps. A plan for “phase 2” of the regional response is being implemented (see Figure 80) and envisions activities through at least December 2014. During the second phase of the outbreak response, the key challenge is to reach the hardest-to-reach—those pockets of children that continue to be missed, especially in Syria’s besieged and conflict areas and in remote and conflict-affected areas of Iraq. Coordinating a response of this unprecedented scale presents daily challenges. The vaccine must be delivered swiftly and repeatedly to tens of millions of children across seven countries. Thousands of mobile teams must go door-to-door. Health centers, where they are functioning and where families are able to reach them, must also have vaccine as well as cross-border refugee registration stations and other sites where populations on the move can be reached. Additionally, the declining security in Syria and Iraq specifically necessitates creative means to access areas previously reachable through the health network. Figure 80. Supplemental immunization activities in response to the Middle East outbreak, January–November 2014 Country</ Territory Egypt Total<SIAs<completed< Total<SIAs<completed<in< from<Oct<2013 2014 NID SNID 2 NID 1 SNID 2014<SIA<activities Jan 1 SNID Iraq 2 1 3 3 5:Jan tOPV Jordan 2 1 Feb SNID< 4:Feb tOPV 1 Mar Apr May SNID NID NID 10:Mar 6:10<Apr 19:23<Oct tOPV tOPV NID NID NID SNID Syria 2 2 2 6 2 6:10<Mar 6:10<Apr 13:17<May 15:19<Jun tOPV tOPV tOPV Nov SNID 10:14<Aug NID NID 14:18<Sep 19:23<Oct bOPV tOPV bOPV SNID SNID NID NID 2:Mar 8:12<Jun 10:14<Aug 26:29<Oct 30<Nov:3<Dec tOPV tOPV tOPV tOPV NID NID SNID SNID SNID NID NID 10:15<Mar 14:19<Apr 15:21<Jul 15:21<Aug 15:21<Sep 15:21<Oct 15:21<Nov tOPV tOPV bOPV bOPV bOPV tOPV tOPV NID NID NID NID NID SNID NID NID 5:Jan 2:Feb 2:6<Mar 6:10<Apr 4:8<May 15:19<June 31<Aug:4<Sep 19:23<Oct 23:27<Nov bOPV bOPV bOPV tOPV bOPV 4 1 Oct bOPV 17:23<Feb bOPV bOPV SNID SNID SNID 7:13<Apr 21:27<May 5:11<Jun NID 1 Sep NID tOPV Palestine< (OPT) Aug NID SNID Turkey Jul tOPV tOPV Lebanon Jun tOPV tOPV tOPV bOPV SNID bOPV SNID tOPV tOPV NID NID tOPV tOPV 12:Jan tOPV SNID Completed)activity NID< Ongoing)or)Planned)activties COMMUNICATION AND SOCIAL MOBILIZATION An estimated 765,000 children <5 years of age currently live in hard-to-reach areas within Syria and lack regular access to vaccines. When aid convoys have managed to enter besieged areas they have carried OPV as a priority item. However, even when children are physically accessible, they may not receive the vaccine because of ongoing violence. Despite the heavy fighting and inaccessibility in many areas, seven vaccination campaigns took place between December 2013 and June 2014 through cooperation with local partners and Page 80 GPEI Partner Status Report - 25 September 2014 volunteers. They were held in schools and health centers, on public buses, and through house-to-house vaccination. During prolonged outbreak response efforts, like Syria, it is always a challenge to keep interest in vaccination high—among caregivers, as well as Governments and healthcare workers. Post- campaign monitoring data from Syria has shown a slight, but consistent increase in missed children between March (7% missed) and June (11% missed). This trend in Figure 81. Reasons for Non-Vaccination among Missed Children in Jordan, caregiver demand is a Syria, Lebanon and Iraq, December 2013–June 2014 significant contributor to missed children here, largely due to the fixed site strategy that relies on parents bringing children for vaccination during each campaign. Where children are accessible, more than 65% of children in the region who don’t receive OPV during campaigns are missed because parents are unaware of campaigns and do not take their children to vaccination centers, do not prioritize polio vaccination among other survival challenges, or do not see the need to ensure that children receive multiple doses of the vaccine. Source: UNICEF Additionally, accessibility has been a challenge in Syria and is the largest barrier to vaccination. In Lebanon, children are missed almost entirely because of social reasons. The vast majority of refusals are due to physicians telling caregivers that children do not need vaccination during campaigns if they have received their routine doses. Caretakers place greater trust in private healthcare to public services, so vaccinators are often turned away at the door. Substantial communication efforts have been underway since April including a mass media campaign launched with private sector pediatricians endorsing OPV and the campaigns. Two high-profile media events were held for journalists in Beirut and Tripoli to launch this media campaign in collaboration with pediatric associations. This work is done in parallel with religious mobilization, social mobilization in predominantly Syrian neighborhoods, and information/education/communication materials provided in private clinics and hospitals. In Iraq, the August campaign marked the first major humanitarian intervention in conflict-affected areas. More than 3.7 million out of an intended 3.97 million children were vaccinated with no major threats to health workers or security incidents. A mass communication campaign has been launched in Iraq to raise risk perception and keep polio high on a crowded humanitarian agenda. Journalists, religious leaders, and youth groups have been engaged to support the polio campaigns. However, approximately 600,000 children are inaccessible in Ninewa and Salah al Din Governorates. Page 81 GPEI Partner Status Report - 25 September 2014 UNICEF’s Regional Office for Figure 82. Facsimle of Proposed Street Drawing to Raise Public Awareness the Middle East is launching about Polio in Syria a region-wide mass media campaign in September that seeks to heighten perceived risk for polio through a series of emotional TV spots featuring a child’s love for his brand new sneakers in which he can no longer run and play. New shoes, a symbol of pride for many in the Middle East, demonstrate what can be lost by not vaccinating children. The TV campaign also features prominent Mock-up of a potential street drawing for Syria, as part of UNICEF’s Regional Communications Campaign. “Don’t allow polio to paralyze your children s’ dreams” pediatricians from the region Source: UNICEF endorsing OPV. The campaign is bolstered by school kits, billboards, and street drawings such as the one shown in the photo. OTHER COUNTRIES/AREAS WITH DETECTION OF ACTIVE POLIOVIRUS TRANSMISSION ISRAEL; THE WEST BANK AND GAZA In June 2013, the Israel Ministry of Health notified WHO that WPV1 had been detected in sewage samples taken in May in a Bedouin town in the Southern District of Israel, part of their extensive environmental surveillance network. Retesting and further sampling in June revealed WPV1 presence in sewage samples taken at this and other sites in the Southern District. Samples were positive during the weeks of 3 February 2013–30 March 2014. These positives were primarily in samples taken at sites in the Southern District, but also included samples taken from sites in the Central District and sporadically samples taken from sites in the Ashkelon, Jerusalem and Tel Aviv Districts. Stool surveys in July 2013 identified WPV1 in a high proportion of specimens obtained through convenience sampling at health facilities from children under 10 years of age residing in the Southern District who had been fully-vaccinated with IPV. Genomic sequencing and phylogenetic analysis suggests that this WPV1 originated from Pakistan and is similar to WPV transiently detected in environmental specimens in Egypt in December 2012 and found circulating in Syria, suggesting broad transmission in the Middle East starting in 2012. No clinical polio cases (WPV-associated AFP) have been identified. In Israel, only IPV has been administered in routine childhood immunization since 2005. Childhood vaccination coverage with 4 doses of IPV is very high (92%–98%). A schedule of IPV/OPV was used from 1990 until 2005. After the WHO-led consultation in June that recommended at least two SIAs with bOPV for the child cohorts vaccinated only with IPV, the Ministry of Health initiated a campaign on 4 August 2013 to administer bOPV to all children aged >2 months born since 2004 in the Southern District of Israel. Two weeks later, the Minister of Health expanded the campaign nationally when WPV1 was detected in sewage samples outside the Southern District. By mid-October 2013, about 70% of the target population had been vaccinated with a dose of bOPV, including about 90% in the Bedouin towns of the Southern District. WPV1-positive samples cultures continued to be identified from samples taken at selected sewage sampling points serving several Southern District communities with Arab populations. Vaccination with a second bOPV dose was recommended in October for children only in those communities and reached about 30% of the Page 82 GPEI Partner Status Report - 25 September 2014 target population. In January 2014, childhood immunization with bOPV at 6 and 18 months of age was initiated (without substantial catch-up for older cohorts), reaching >90% coverage at age-appropriate visits. With a sporadic positive sample in Tel Aviv along with some other sporadically positive sites in the Southern District in February 2014, only one collection site (Ar’ara) in the Southern District remained positive after midFebruary. The Ar’ara site was intermittently positive for the samples collected during December through March, with the last identified in the sample collected in the week of 30 March. In the West Bank and Gaza, a sequential IPV/OPV schedule was introduced in 1990 and remains in use. WPV1 was intermittently detected in sewage samples taken at routinely tested sites in the West Bank in July through October 2013 and in Gaza in August 2013 through January 2014, the most recent being taken on 5 January 2014. Full SIAs were conducted with tOPV in the West Bank and the Gaza during November and December 2013. No polio cases have been identified in the West Bank and Gaza. COUNTRIES AT RISK COUNTRIES WITH RECENT POLIOVIRUS TRANSMISSION Countries that have stopped transmission of indigenous WPV are subject to the risk of WPV importation from remaining reservoirs. Depending on the level of immunity in the population, outbreaks can result. Although substantial epidemics resulted after WPV1 importation into Tajikistan and other countries in the European Region in 2010 and into China in 2011, the primary risk of outbreaks remains in the WPV-endemic regions of WHO — the African (AFR) and the Eastern Mediterranean (EMR) Regions. Many outbreaks in polio-free countries occurred in the “WPV importation belt” of the African Continent — a band of countries from West Africa to the HoA with outbreaks from the West African B (WEAF-B) WPV1 genotype originating from Nigeria. Additional outbreaks occurred in South/Central African countries due to South Asian (SOAS) WPV1 genotype originating from India. The 2013–2014 WPV1 outbreaks in the HoA, Central Africa, and the Middle East demonstrate the ongoing risk for spread after importation from Nigeria, Afghanistan and Pakistan, even in the face of preventive SIAs in some areas. Additionally, emergence and transmission of cVDPVs have occurred in some of these same outbreak countries as well as other countries in AFR (Mozambique) and EMR (Yemen) with compromised population immunity. There are 29 previously polio-free countries in AFR (Angola, Benin, Burkina Faso, Burundi, Cameroon, CAR, Chad, Congo, Côte d’Ivoire, DRC, Ethiopia, Equatorial Guinea, Gabon, Guinea, Kenya, Liberia, Mali, Mauritania, Mozambique, Niger, Senegal, Sierra Leone, [South] Sudan, Togo and Uganda) and EMR (Iraq, Somalia, Syria, Yemen) in which WPV and/or cVDPV transmission has occurred since 2009 that are subject to ongoing risk for poliovirus transmission. Here presented are surveillance performance indicators and dose-histories in NPAFP cases (reflecting immunity status) in 50 countries — the three WPV1-endemic countries plus the 29 previously-listed polio-free countries with WPV and/or cVPDV outbreaks and 18 selected neighboring countries (Djibouti, Eritrea, Egypt, Gambia, Ghana, Guinea-Bissau, Iran, Israel [in the WHO European Region], Jordan, Lebanon, Libya, Malawi, Namibia, Rwanda, Sudan, Turkey [in the WHO European Region], Tanzania, Zambia). We also present an overview of the assessment of risk of WPV transmission based on NPAFP dose history, history of outbreaks and proximity to transmission, indicators of routine immunization system delivery and other factors that were recently evaluated by Risk Assessment Task Team comprised of WHO, CDC and the Institute of Disease Modelling (Global Good) along with the Bill and Melinda Gates Foundation and UNICEF to arrive at a consensus on which countries are at highest risk in the AFR and EMR as well as selected countries of other regions. Lastly, mitigating activities in 2014 are briefly reviewed. Page 83 GPEI Partner Status Report - 25 September 2014 SURVEILLANCE PERFORMANCE An article simultaneously published 25 April 2014 in CDC’s Morbidity and Mortality Weekly Report and WHO’s Weekly Epidemiologic Record assessing surveillance indicators for 2012–2013 highlighted a deterioration of surveillance indicators from 2012 to 2013 among the 30 countries evaluated, primarily in AFR countries and primarily due to a decrease in the proportion of AFP cases with collection of adequate specimens. Updating those indicators for the 50 countries evaluated here for the time period of this report, 27 (84%) of 32 countries with poliovirus cases during 2009–2014 and 14 (78%) of 18 neighboring countries met the national target of an annual rate of ≥2 NPAFP cases per 100,000 population aged <15 years. The five Figure 83. AFP surveillance indicators at first administrative level, for AFP cases with onset 16 August 2013–15 August 2014, 50 selected AFR, EMR and European Region countries Source: CDC countries with cases from poliovirus transmission where the NPAFP rate indicator did not meet the national target were all from the AFR region: Benin (1.45), Central African Republic (1.26), Gabon (0.99), Liberia (1.58) and South Sudan (0.75). The four neighboring countries that didn’t meet the national target for this indicator include one in AFR: Malawi (1.5); one in EMR: Djibouti (1.4); and two in EUR: Israel (1.5), and Turkey (1.2). The national target of ≥80% of AFP cases with adequate stool specimens was met by 42 (84%) of 50 countries over the last 12 months. The eight countries where the stool adequacy rate indicator did not meet the target were five in AFR: Equatorial Guinea (8%), Ethiopia (78%), Gabon (10%), Guinea-Bissau (67%), and Malawi (75%); two in EMR: Lebanon (69%), and Syria (75%); and one in EUR: Israel (77%). Page 84 GPEI Partner Status Report - 25 September 2014 Figure 83 presents composite surveillance indicators for the previous 12 months at a sub-national level (state/province) for 32 countries reporting poliovirus (WPV or cVDPV) cases from transmission during 2009– 2014 and 18 selected neighboring countries highlighting sub-national weaknesses that are masked by overall national data. These data suggest that suboptimal surveillance limited the prompt detection of outbreaks in most of the countries affected by importations in 2013–2014 which would have allowed more timely outbreak response activities and potentially limited the extent of each outbreak. Sub-national AFP surveillance quality was variable, noting a failure to meet one or both indicators in major areas of several countries in close proximity to Nigeria, including Benin, Cameroon, Central African Republic (CAR), Congo, Equatorial Guinea, Gabon, Mali, and Niger. In addition, there were notable deficiencies in parts of several countries in the HoA, including Ethiopia, Eritrea, South Sudan, and Uganda. The other countries that reported a failure to meet one or both indicators in major areas are: Angola, Burkina Faso, Liberia, Mauritania, Mozambique, Senegal, Tanzania, Togo, Iraq, Pakistan, and Syria. Additionally, indicators may be met in areas that nonetheless have substantial weaknesses in case detection. IMMUNIZATION STATUS Figure 84 presents immunization status indicators at a sub-national level for these 50 countries. The immunization status of children was assessed using dose history for children 6–35 months of age with NPAFP over the previous 12 months and looked at the proportion of children with no history of OPV doses (0-dose) and the proportion with >4 OPV doses. Despite SIAs in this period in most of these countries, a high number of countries have numerous sub-national areas in which <80% of children have >4 OPV doses, and many of those areas have >10% of children with 0-dose history. Most of the same countries with limited sub-national indicators of surveillance exhibit substantial weaknesses in population immunity and ongoing risk for further spread of WPV, particularly in Central Africa and the HoA. Validity and interpretation of data is of concern when dose history is missing for ≥20% of NPAFP cases, as in eight countries in AFR: Malawi (55% [26 of 47]), Namibia (50% [13 of 26]), Senegal (37% [36 of 97]), Mozambique (31% [48 of 156]), Central African Republic (30% [14 of 47]), Zambia (29% [23 of 80]), Ethiopia (28% [131 of 461]), Benin (24% [36 of 147]); and one country in EMR: Jordan (24% [4 of 17]). HIGH-RISK PRIORITY COUNTRIES In September 2014, GPEI recently repeated a cross-agency review of vulnerability and factors affecting risk for exposure (Risk Assessment Task Team). This risk assessment is to be revised quarterly and forms the basis for prioritization of countries for SIAs and other mitigating activities. In addition, some countries included in outbreak response plans in the HoA (e.g., portions of Kenya, Uganda, Djibouti, Yemen, South Sudan) and the Middle East (e.g., Jordan, Lebanon, portions of Turkey) are at least as vulnerable as other countries currently assessed as high or medium high on the risk list. The outbreak response in those areas is not limited solely to interrupting transmission in countries affected by the outbreak but is also working to reduce the risk of importation in unaffected countries in the area. Outside of those two outbreak response zones, countries considered to be at the highest risk for polio outbreaks are the following eight countries: Central Africa outbreak zone: Chad, Congo, CAR, portions of the Democratic Republic of the Congo (DRC) and Gabon; Other: Benin, Niger, and Mali. The Outbreak Risk Mitigation Task Team has decided to prioritize among the high-risk countries and focus on Congo, CAR, Gabon and Niger. Page 85 GPEI Partner Status Report - 25 September 2014 Many other countries are considered at potential risk, and are also recommended to undertake national or subnational SIAs as appropriate to mitigate risks. These include, among others, the Philippines and Ukraine. The latter has a worsening immunity gap that is chronically based on low trust in government and the immunization programme, as well as acutely low vaccine supply due to lack of financing; further compounded by the current conflict and political crisis; mitigating this gap in Ukraine will be problematic but contingencies are being examined. Figure 84. Immunization status at first administrative level, for children 6-35 months of age with NPAFP cases with onset 16 August 2013–15 August 2014, 50 selected AFR, EMR and European Region countries Source: CDC MITIGATING ACTIVITIES The global SIA schedule was reviewed in late April 2014, and the partnership decided to increase the number of SIAs planned for the second half of 2014 in at-risk countries. Increasing SIA number/frequency, however, is only one means of attempting to reduce risk. To address other priorities in mitigating risk, such as improving SIA quality and enhancing surveillance, GPEI has recently created the Outbreak Risk Mitigation Task Team to work with the African Regional Office in planning activities in these approaches. Page 86 GPEI Partner Status Report - 25 September 2014 VACCINE SUPPLY AND MANAGEMENT INTRODUCTION In 2014 so far, UNICEF has been able to supply both OPV and IPV for the programme to implement all planned immunization campaigns without any delays or cancellation of activities. The IMB report of May 2014 made a specific recommendation on increasing the OPV supplier base in Nigeria and Pakistan. This report also expressed concerns regarding the quality of in-country vaccine stock management and the need to finalize national plans for use of IPV in SIAs. Significant progress has been made on expanding the bOPV supplier base in Nigeria, but not in Pakistan. Plans have been developed for some IPV use in SIA in 2014 and IPV was supplied to Afghanistan, Nigeria and Pakistan keeping supply provisions intact for planned IPV introduction in routine immunization. UNICEF continues to implement pilots to improve in-country vaccine management but progress remains a challenge as it is not yet viewed as a priority among all emergency activities in affected countries. There are also challenges with data quality and vaccine inventory systems. With inputs from partners, UNICEF has developed an internal technical guidance note on vaccine management during polio SIAs. UNICEF also collaborated with CDC to include a training module on polio vaccine management during SIA into the STOP team training of the 44th team, which was conducted in June 2014. OPV SIA: SUPPLY AND DEMAND FOR SECOND HALF-2014 – Q1 2015 Since May 2014, because of additional awards made in Q4 2013, the supply situation has dramatically improved for OPV, with sufficient buffer to meet potential increases in demand for the second half of 2014. As of September 2014, global OPV supply for the second half of 2014 is sufficient including the availability of buffer into Q1 of 2015 (see Figure 85). Additionally, after approval of the final 2014 SIA calendar by the Eradication Management Group and Polio Steering Committee in May 2014, stress testing for supply availability was conducted and supply should be sufficient through Q1 2016. UNICEF is in the process of making awards to manufacturers for additional supply of bOPV and tOPV in 2015 to maintain a minimum of a 40 million dose buffer of bOPV and 30 million dose buffer of tOPV. Since 2012, UNICEF has been working with Pakistan and Nigeria country offices to accelerate/increase the number of licensed products to increase security of supply and allowing further flexibility in managing demands globally and in these two countries. For Nigeria, there has been licensure of additional bOPV suppliers (two products licensed, two more in the process of finalizing registration). Nigeria has also been accepting delivery of non-license vaccine against issuance of import waivers on a campaign-by-campaign basis, including from Indian manufacturers. Licensure is no longer a limitation for supply allocation but if granted would expedite supply. Progress for Pakistan has been limited. UNICEF is working with Pakistan to increase the supplier base but this has been unsuccessful in additional registered products. There are still only two suppliers licensed for both tOPV and bOPV. This continues to constrain the bOPV supplier base for Pakistan. Page 87 GPEI Partner Status Report - 25 September 2014 Figure 85. OPV monthly demand vs. balance supplies: July 2014 to March 2015 (Projected) IPV IN SIAS: SUPPLY UPDATE The requirements of the IPV tender concluded in Q1 2014 were based on projected demand for introduction in routine immunization (objective 2). Delays in IPV introduction plans reduced the IPV requirements in 2014 and increased availability for SIAs in 2014. This enabled the programme to allocate 5.4 million IPV doses for SIAs in endemic countries in 2014. This quantity has been divided as follows: • • • Afghanistan Nigeria Pakistan 0.6 million doses 2.1 million doses 2.7 million doses of which 1.7 million doses has been funded In Pakistan, all 400,000 IPV doses which have been already delivered remain unused due to delays in government decision in conducting IPV SIAs. On the other hand, encouraged by the successful implementation of IPV in SIA in Borno and Yobe, Nigeria Expert Review Committee has recommended further use of IPV in campaigns in selected LGAs of Kano. The Nigeria country team is working out the additional IPV doses required. Page 88 GPEI Partner Status Report - 25 September 2014 Because of delay in licensure and reduced supply availability 2014-2015, global IPV supply will be very constrained in order to meet the upcoming planned routine immunization introductions. Adding SIA requirements leads to a projected moderate supply gap for 2014-2015. The Immunization System Management Group has agreed to allocate specified quantifies of IPV doses for use in campaigns (4-7 million doses in 2015) but is requesting that the programme communicates the plans and needs for 2015 as soon as possible. The Eradication Management Group has developed clear criteria to guide countries on IPV use in SIAs and has communicated this to the three endemic countries with a request to provide detailed plans for IPV SIAs in 2014 and 2015 with the Immunization Systems Management Group and Supply Division which will be reviewed against the projected IPV introduction plans by end of September 2014. IN-COUNTRY VACCINE MANAGEMENT AND STOCK INVENTORY The recent IMB report expressed concerns regarding the in-country vaccine stock management. They indicated that this “is wasteful, potentially constraining the amount of vaccine that can be deployed elsewhere. Tighter inventory control would help significantly.” In an effort to improve in-country vaccine management especially during polio SIAs, UNICEF, in collaboration with partners, is now leading several initiatives. Most of these are initial pilots and low-cost initiatives that build on existing opportunities. • • • • • UNICEF, with inputs from partners, regional offices and country offices, has developed a “Guidance note on vaccine management during polio campaigns” which lays out key programmatic roles and responsibilities at different levels and identifies priorities, processes, indicators and tools. This is being rolled out gradually with focus on the endemic countries. Stock inventory reporting template: West and Central Africa Regional Office have also piloted a UNICEF Headquarters (HQ) template for reporting on national and sub-national polio vaccine utilization and stocks in countries. This has been helpful to account for available vaccine stocks prior to further procurement orders by the country. Nigeria specifically has also been strengthening efforts on stock inventory and was able to use surplus OPV doses to cover the needs of a full SNID in May, 2014. Building in country capacity: In collaboration with CDC, UNICEF HQ has developed and delivered a curriculum for the first training session on vaccine management targeting STOP (44th batch- June 2014) team members. STOP consultants are deployed to the field in the high priority countries to support eradication activities. This has been well received and we plan to continue building on it and to develop an interactive web-based training module that also links this to the guidance note. .It would be critical to continue this effort as part of integrating vaccine management training into the overall curriculum. Cold chain capacity: members of the COMNet in Pakistan have been trained on conducting a cold chain inventory and have completed this exercise and collected and analyzed the data for all high risk districts in the country. These data have been critical to highlight gaps in the system and advocate with local and provincial authorities on the importance of urgently addressing these gaps to strengthen cold chain for polio SIAs and routine immunization in general. Most recently, in July, this was used to assess cold chain capacity and status of health facilities in South Waziristan. Vaccine management and cold chain and logistics indicators: UNICEF's internal polio management dashboard for the endemic countries uses two such indicators—but the challenge is in getting the whole programme and relevant structures at various levels to adopt and use such indicators to monitor Page 89 GPEI Partner Status Report - 25 September 2014 this area of work. Some developments occurred with inclusion of vaccine management indicators in Pakistan’s revised National Emergency Action Plan in 2014. PRIORITY AREAS OF FOCUS IN NEXT 3-6 MONTHS The programme continues to invest resources in vaccine supply management and the following areas still require further work by the partnership. • Availability, quality and use of polio vaccine utilization data during SIAs by the programme at various levels. It is critical for country teams to be fully engaged with this work and ensure that the vaccine management and cold chain data are being collected regularly and used and the need to do so is not viewed as a duty of one partner or agency. The minimum requirement would be for the programme to review, analyze and use the following data and include it in all GPEI data platforms: o Number of OPV doses delivered, used and remaining after each SIA at district, provincial and national level o Available polio vaccine stock by type of (tOPV, bOPV, IPV) on a monthly basis o Number of sites reporting vaccine stock-outs during each SIA by district level These data should be incorporated into regular reports from countries. • • • Focus on cold chain and vaccine logistics systems: GPEI partners will be looking at opportunities for strengthening cold chain and logistics systems in the highest risk areas in the priority countries utilizing polio infrastructure in place and using these data to advocate with local authorities to address existing gaps GPEI is updating the 2015-2016 calendar for both OPV and IPV SIAs and incorporate considerations to mitigate any risk for outbreaks ahead of the tOPV to bOPV switch in routine immunization. Continued need for close and joint monitoring of supply and demand and ensure that all vaccines are supplied in time for planned SIAs (OPV and IPV) and that requests for vaccines outside of the approved SIA calendar are assessed and decided on by appropriate global bodies before any allocations are made. Many of the efforts related to SIA activities will also contribute to strengthening the overall vaccine management, cold chain and logistics systems in countries, as well as to the improvement of routine immunization and facilitating the tOPV to bOPV switch. Page 90 GPEI Partner Status Report - 25 September 2014 STAFFING AND CAMPAIGNS IN 2014 Consultants GPEI consultants by deployment, 2014 WHO Paid Consultants BMGF Sponsored Afghanistan 12 12 Cameroon 51 CAR 2 Country Chad Congo 10 3 DRC 5.5 Djibouti 3 Equatorial Guinea 19 Ethiopia 24 Gabon 6 Iraq 12 Jordan 25 16 Kenya 26 2.5 Nigeria 38 22 Pakistan 9 27.5 1 Niger Somalia South Sudan 7 Switzerland 8 Syria Turkey 9 2.5 Uganda Yemen WHO Headquarters Total 11 256 110 Page 91 GPEI Partner Status Report - 25 September 2014 Staffing & SIA Campaigns 2014 1 Country#Staffing#for#Polio Region Country Afghanistan Endemic# Pakistan Nigeria Algeria Angola Benin Botswana BurkinaAFaso Burundi Cameroon CapeAVerde CentralAAfricanA Republic Chad Congo CôteAd'Ivoire DemocraticA RepublicAofAtheA Congo Eritrea Ethiopia AFR UNICEF WHO 2 NIDs SNIDs 5 Polio#Program# 3# CDC#Staff#&# NSTOP Supporting# partners 3 32 1 209 Rotary 6 7 8 Core Surge Surge#&#Soc# Core Mob 9 STOP 272 28 2,892 7 4 35,842 9 22,173 $62.2 485 70 1,771 3 5 171,584 12 133,290 $146.2 25 314 2297 33 9,844 29 $273.4 2 117,925 9 191,680 0 0 0 0 3 80 5 4 7 4 $0.0 6 2 14,206 0 0 $11.7 2 3 9,855 0 0 $4.7 1 0 0 0 0 16 6 3 $0.2 2 4 25,440 0 0 $12.0 9 1 0 0 0 0 $0.0 4 7 31,304 4 15,050 $18.4 2 125 0 0 $0.2 2 948 5 3,026 $3.3 $16.2 0 1 Costs (USD,# millions) 239 3 0 9 1 3 35 1 4 9 15 16 6 93 2 No. Target# (thousand) 145 0 1 No. Target# (thousand) 8 0 1 Total#No. 41 0 EquatorialAGuinea Gabon Gambia Ghana Guinea GuineaSBissau Kenya Liberia Madagascar Malawi Mali Mauritania Mozambique Namibia Niger Rwanda Senegal SierraALeone SouthAAfrica SouthASudan Swaziland Tanzania Togo Uganda Zambia Zimbabwe 2014#Polio#Campaigns 4 CDC 0 6 11 73 35 9 4 16 14 3 11,189 2 3,769 4 4 4,122 0 0 $3.2 4 3 23,034 0 0 $10.2 20 2 28,761 1 6,424 $39.0 0 0 0 0 $0.3 2 21,737 6 20,201 $30.1 3 43 18 18,688 1 7 0 6 1,598 1 4 $2.6 1 1 3 1,991 0 0 $1.4 0 2 810 0 0 $0.6 0 2 11,431 0 0 $5.2 3 0 0 0 0 $0.0 2 0 2 576 0 0 $0.7 3 9 2 17,137 5 21,784 $24.6 $0.0 0 0 5 2 0 2 7 4 3 2 0 3 7 13 3 7 4 0 0 0 0 0 9 1 0 0 0 0 $0.5 0 2 0 0 0 0 $0.3 6 4 4 3 21,563 1 3,503 $8.5 0 1 3 2 1,214 0 0 $1.4 0 5 2 0 0 0 0 $0.6 0 4 0 0 0 0 0 $0.4 5 21 4 4 22,323 3 7,337 $17.6 0 3 2 0 0 0 0 $0.3 0 3 2 2 4,977 0 0 $2.5 0 7 3 0 0 0 0 $0.0 0 8 0 0 0 0 $0.7 0 446 0 3 0 7 3 5 3 12 0 0 6 1 3 1 12 4 12,374 0 0 $12.3 0 0 0 0 $0.2 0 0 0 0 0 $0.8 1 2 3,944 0 0 $2.0 4 2 9,714 1 3,806 $6.4 9 0 0 0 0 $0.9 3 0 0 0 0 $0.4 1 1 2 18 Page 92 ! GPEI Partner Status Report - 25 September 2014 1 Country#Staffing#for#Polio Region AMR EMR EURO SEAR WPR All Country CDC#Staff#&# NSTOP Haiti Djibouti Egypt Iran Iraq Jordan Lebanon Somalia Sudan SyrianFArabF Republic Yemen EMRO Kyrgyzstan RussianF Federation Tajikistan Turkey Uzbekistan Bangladesh India Indonesia Myanmar Nepal Cambodia China Phillipines VietFNam Total 2014#Polio#Campaigns WHO4 CDC Supporting# partners Rotary 6 UNICEF 7 8 Core Surge Surge#&#Soc# Core Mob 1 11 2 SNIDs5 NIDs 9 STOP Total#No. No. Target# (thousand) No. Polio#Program# Target# (thousand) Costs3#(USD,# millions) 4 0 0 0 0 1 2 250 1 51 $0.4 2 25,891 0 0 $2.2 2 $0.0 1 5 28,642 4 8,220 $4.2 6 3 1 3 2,784 2 350 $2.4 6 2 4 2,843 3 200 $4.6 2 8 15,707 7 5,958 $26.0 0 2 12,311 1 4,427 $13.9 9 21,980 1 1,846 $9.0 4 20,707 0 0 $6.3 0 0 0 0 $0.01 0 0 2 1,173 $0.0 2 2,087 0 0 $0.3 0 0 4 2,011 $0.7 0 0 0 0 $0.03 1 185 4 40 15 12 69 37 5 17 15 1 4 1 2 2 21 103 4 32 1160 17 6 11 9,125 0 $2.5 273,372 $46.6 0 0 0 0 $1.6 0 0 0 0 $0.8 1 4,803 0 0 $2.1 0 0 0 0 $0.0 0 0 0 0 $0.0 2 27,247 0 0 $0.0 0 0 0 0 $0.0 127 1,133,457 87 729,655 $846.1 57 1 3 279 0 3 49 1 11 0 362,483 50 0 245 0 2 3360 3202 255 42332 184 0 1. Does not include staff at other levels 2. Includes National Immunization Days (NIDs), Subnational Immunization Days (SNIDs), Mop ups, and Child Health Days (CHDs) 3. Includes AFP surveillance, Social Mobilization, Technical Assistance, OPV, and Operational Costs. Costs for CHDs and CDC programmes not included 4. The number in yellow background was not updated since last report (April 2014) 5. Concurrent SNIDs in different geographical areas were counted separately 6. CDC secondees to WHO country offices and contractors are also counted as WHO core staff 7. Includes both volunteers and paid staff. 8. Includes international and national technical staff 9. Stop Transmission of Polio (STOP) round 44, deployed July-December, 2014. One STOP volunteer was assigned to Papua New Guinea (WPR). Page 93 ! GPEI Partner Status Report - 25 September 2014 FINANCING GLOBAL POLIO ERADICATION INITIATIVE FINANCING SITUATION FUNDING GAP Against the US$ 5.5 billion budget for 2013-2018, the best-case funding gap for the entire period is US$ 494 million (Table GPEI Funding Gap as of July 2014, below). The best case funding gap represents the difference between the total costs budgeted in the endgame plan less a) pledges made at the 2013 vaccine summit, b) pledges made after the summit, and c) projections for donors who have not made publically announced funding commitments but who have historically provided support and have indicated that they will continue to do so. GPEI Funding Gap as of July 2014 Funding Gap 2013-2018 2013-2018 USD millions Feb 2013 Jul 2014 (pre-Vaccine Summit) (Millions) (Millions) Funding Required (FRRs) $5,525 $5,525 Confirmed Funding $ 395 $1,986 Pledged Funding $ - $2,698 Projected Funding $3,100 $ 347 'Best Case' Funding Gap $2,030 $ 494 Source. GPEI. This level of commitment from donors over the entire period of the plan represents a historic shift in the way the Initiative is funded and has enabled stronger forward planning, more discipline in budget control and supported a faster response to the two major outbreaks of 2013. It is important to note that pledged funding does not represent cash available to the Initiative. Changes in political leadership or economic downturns present a risk that pledges will not be honored. In addition, none of the donors who pledged at the Vaccine Summit were in a position to make a full payment of the pledges immediately and the timing of the operationalization of pledges has an impact on programme implementation. Page 94 GPEI Partner Status Report - 25 September 2014 CASH GAP The cash gap represents the GPEI’s internal operating position in the near term based upon cash available for expenditure. As of July 2014, the Initiative has cash on hand of US$ 908 million against the total budget of US$ 1.1 billion for 2014 (Figure 86). Figure 86: GPEI Cash Gap for 2014 as of July 2014 The remaining cash gaps for 2014 are in budget categories for SIAs and emergency response. The majority of these gaps will be covered from forthcoming contributions from GPEI partners (Bill and Melinda Gates Foundation, CDC supplements, and private philanthropists). The cash gap projections for 2015 will be developed once the 2015 SIA calendar (currently being finalized by the Eradication Management Group) is approved. IMB RECOMMENDATIONS In its Ninth Report of May 2014, the IMB recommended that current concerns and unease about the transparency and communication of the polio eradication budget are properly and openly addressed and suggested that this might best be achieved by a frank discussion at the Polio Oversight Board. In order to better understand these issues, a follow-up call was held with members of the IMB secretariat. Following this, the topic was also discussed at the 16 June 2014 meeting of the Polio Partners Group. The outcome of these conversations resulted in the identification of 5 key issues to be addressed: 1. 2. 3. 4. 5. More details on allocations and cash gaps against budget lines Clear reporting on domestic contributions Reporting on expenditure against budgets Split of costs for polio eradication versus routing immunization More information on IPV introduction (GAVI vis-à-vis GPEI budget; whether all vaccine costs are included in the GPEI budget) These issues and next steps were presented and discussed during the Finance and Budget update at the 20 June POB meeting. The POB chair noted that the Finance Working Group should develop ways to provide more clarity both in reporting and communication on expenditures, future funding and cash gaps, including a Page 95 GPEI Partner Status Report - 25 September 2014 more detailed breakdown of the gaps, the projected contributions that could close the gaps and the risks to realizing the projected contributions. The POB made a recommendation that the GPEI should provide more detailed and regular financial reporting to donors, including financial expenditures. In addition, the POB supported the introduction of a semi-annual budget and cash-flow review during their meetings. The following initial steps have been taken to address the 5 key issues above: 1. More details on allocations and cash gaps against budget lines – the following two charts will be introduced in the July 2014 FRR Page 96 GPEI Partner Status Report - 25 September 2014 2. Clear reporting on domestic contributions – this information is found in the Vaccine Summit reporting table in the July 2014 FRR; information on trends in domestic funding will also be introduced in the July FRR: Confirmed& Confirmed& Funds&Committed& New&Funding& Funding&against& Funding&against& by&April&2013& received&since&Feb& the&GPEI&FRRs,&as& the&GPEI&FRRs,&as& Vaccine&Summit 2014& of&February&2014 of&31st&July&&2014 G8&&&EC Canada $243.53 $65.08 $37.64 $102.72 $6.50 $5.80 $8.16 $13.96 $151.70 $53.96 $0.00 $53.96 $9.70 $457.00 $90.60 $14.80 $296.31 $129.85 $6.44 $1.33 $60.73 $21.24 $297.64 $190.58 $34.55 $34.55 $34.55 $0.53 $0.53 $0.53 $6.50 $0.70 $252.45 $6.63 $0.70 $12.45 $0.05 $0.14 $0.02 $0.35 $15.00 $0.05 $0.05 $0.02 $0.35 $15.00 $1.00 $120.00 $1.00 $12.00 $12.00 $1.00 $24.00 Bill6&6Melinda6Gates6Foundation Korean6Foundation6for6International6Healthcare/6 Community6Chest6of6Korea $1,800.00 $363.77 $47.88 $411.65 $1.00 $2.00 Private6Philanthropists/High6Networth6Individuals $335.00 $51.20 $27.10 $78.30 $76.81 $0.75 $156.45 $0.07 $3.55 $160.00 $0.07 $24.00 $227.00 $64.50 $10.00 $24.00 $137.28 $22.75 $10.00 $12.92 $36.92 $137.28 $40.75 $10.00 $50.00 $50.00 $50.00 $4.27 $10.40 $10.40 $7.30 $10.00 $0.90 $6.54 $10.00 $0.67 $22.80 $6.54 $10.00 $0.67 $28.30 European6Commission Germany Japan United6Kingdom USA NonTG8&OECD&Countries Australia1 Finland Ireland Luxembourg Norway2 Other&Donor&Countries Brunei6Darussalem Isle6of6Man Liechtenstein Monaco Saudi6Arabia Private&Sector/&NonTGov't&Donors Al6Ansari6Exchange Abu6DhabiRCrown6Prince 3 3 Rotary6International UN6Foundation Multilateral&Sector GAVI/IFFIm6 Islamic6Development6Bank/6Government6of6Pakistan UNICEF6 World6Bank6(Grant6to6Afghanistan) World6Bank6Investment6Partnership,6Bank6Portion World6Health6Organization Domestic&Resources Angola Bangladesh Nepal Nigeria TOTAL 1 4 $40.00 $4,041.85 $1,517.06 $0.35 $160.00 $0.23 $6.63 $1.05 $172.45 $0.05 $0.05 $0.02 $0.58 $15.00 $2.00 $18.00 $5.50 $401.83 $1,918.89 6In6June620146Prime6Minister6Tony6Abbot6reaffirmed6the6pledge6of6806million6USD6towards6the6Polio6Eradication6Strategic6Plan6and6Endgame 36 Funds6for620136under6the6$3556Million6Challenge6Grant6from6the6Bill6&6Melinda6Gates6Foundation6to6Rotary6International6is6reflected6in6both6the6 Bill6and6Melinda6Gates6Foundation6and6Rotary6International6contribution6lines,6though6the6contribution6is6only6counted6once6in6the6GPEI6totals.6The6 same6applies6for6a6$506million6grant6for62013R2015.6In62013,6Rotary6pledged6up6to6$1756million6for62013R2018,6which6will6be6matched62:16by6the6Bill6 &6Melinda6Gates6Foundation.6Contributions6from6both6under6this6match6scheme6will6be6reflected6as6and6when6funds6are6confirmed.6Rotary's6 contributions6to6the6GPEI6are6through6the6Rotary6Foundation. Page 97 GPEI Partner Status Report - 25 September 2014 3. Reporting on expenditure against budgets – this report is being finalized for publication during October 2014. Effective in 2015, this information will be a regular segment of the annual report. 4. Split of costs for polio eradication versus routine immunization – the July 2014 FRRs have an expanded section on costs that contribute to routine immunization (RI) strengthening, and will include the following chart: Budget Category and Funding Channels Technical Assistance GPEI* IMG Technical assistance 2014 - 15** One-time RI strengthening activities 2013 GPEI TOTAL RI Strengthening GPEI Budget Category Core Functions and Infrastructure: Technical Assistance (WHO) Core Functions and Infrastructure: Ongoing Quality Improvement Core Functions and Infrastructure: Ongoing Quality Improvement Total 2013-2018 $228M $5M $8M $241M *In 10 priority countries: 50% of field staff time at sub-national levels; 25% at national levels. **Costing included under the IMG work plan/IPV introduction 5. More information on IPV introduction (GAVI vis-à-vis GPEI budget; whether all vaccine costs are included in the GPEI budget) – As with routine immunization, there is an expanded section on IPV Page 98 GPEI Partner Status Report - 25 September 2014 introduction in the July 2014 FRR which addresses these concerns, and includes the follow table detailing budgetary information: 6. IPV Introduction Budget Category and Funding Channels Vaccine costs: GAVI Introduction grants: GAVI Introduction support: GPEI GPEI Budget Category Immunization Activities: IPV in Routine Immunization Immunization Activities: IPV in Routine Immunization Immunization Activities: Total 2014-2018 $342M $46M $45M IPV in Routine Immunization IMG Technical assistance •!!!!!!!!!IPV: GAVI/GPEI •!!!!!!!!!RI Strengthening: GAVI/GPEI •!!!!!!!!!tOPV/bOPV switch: GPEI TOTAL Core Functions and Infrastructure: Ongoing Quality Improvement $50M $483M After publication of the July 2014 FRR and the WHO/UNICEF expenditure report, there will be follow-up discussions with key stakeholders to assess progress on these efforts and further refine response strategies. Additional work will be undertaken in the next period to refine the reporting further and address the request of the POB chair for inclusion of additional information in subsequent FRRs. ROTARY SUPPORT Rotary continues to draw from its global volunteer network to raise awareness and funds for the Global Polio Eradication Initiative. As a result of these enhanced efforts and in partnership with the Gates Foundation, Rotary committed US$105 million in funding for polio eradication in calendar year 2013 and expects to do the same in 2014. Rotarians continue to advocate with donor governments to help meet critical funding needs, both within the polio affected countries and in key donor markets. Rotary’s advocacy efforts have largely focused on the following key markets, the US, UK, Canada, Japan, Australia, Germany, and the EU. Of note, the Prime Minister of Australia announced a pledge of A$100 million at Rotary’s convention in June 2014 for global polio eradication efforts. Page 99 GPEI Partner Status Report - 25 September 2014 ANNEX: LIST OF FIGURES Figure 1. WPV sanctuaries in polio-endemic countries, and countries and areas with wild poliovirus transmission within the prior 12 months, 19 September 2014 Figure 2. Proportion of targeted children missed due to refusal, January 2013–August 2014 Figure 3. Missed children in high risk areas of endemic countries, October 2013-August 2014 Figure 4. Number of social mobilization networks, January 2013–August 2014 Figure 5. UNICEF performance dashboard for frontline workers, Endemic countries, Sept 2014 Figure 6. Poll Responses Regarding Trust in Vaccinators, Nigeria and Pakistan Figure 7. Gender profile of frontline workers, July 2013-June 2014 Figure 8. WPV and cVDPV cases, Afghanistan, 2013 and 2014 to date* Figure 9. Wild poliovirus type 1 (WPV1) by genetic cluster and circulating vaccine-derived poliovirus type 2 (cVDPV2) by emergence, Afghanistan & Pakistan, 2013 and 2014 to date* Figure 10. WPV and cVDPV cases, Southern Sanctuary, 3 September 2013 to 2 September 2014* Figure 11. WPV and cVDPV cases by week of onset, Southern Sanctuary (Helmand and Kandahar Provinces), Afghanistan, 3 Sept 2013 to 2 Sept 2014* Figure 12. LQAS survey results by SIA, Southern Sanctuary, Afghanistan, Sept 2013 to Aug 2014 Figure 13. Proportion of NPAFP cases 6-35 months, by OPV status, Southern Sanctuary, Afghanistan** Figure 14. WPV and cVDPV cases, Eastern Risk Area, 3 September 2013 to 2 September 2014* Figure 15. WPV and cVDPV cases by week of onset in the Eastern Risk Area (Kunar, Nangarhar, Laghman, Nuristan, Khost, and Paktya Provinces), Afghanistan, 3 Sept 2013 to 2 Sept 2014* Figure 16. LQAS survey results by SIA in the Eastern Risk Area Afghanistan, Sept 2013 to Aug 2014 Figure 17. Proportion of NPAFP cases 6-35 months, by OPV status, Eastern Risk Area, Afghanistan** Figure 18. Trends in missed children in accessible, high-risk areas in Afghanistan, Oct 2013-Aug 2014 Figure 19. Proportion of missed children and missed because of refusal among targeted children in selected LPDs in Southern Afghanistan, October 2013 to August 2014, Figure 20. Polio related security incidents in Afghanistan, Feb-Sep 2014 Figure 21. Proportion of Missed Children due to Inaccessibility among Targeted Children <5 years of age, by Region, Afghanistan, October 2013 to August 2014 Figure 22. Inaccessible areas, 2014 WPV1 cases, and the estimated proportion of children affected during the August 2014 SIA - Eastern Risk Area and Southern Sanctuary, Afghanistan Figure 23. Six-month standard immunization indicators among children aged 6–35 months with NPAFP and annualized surveillance indicators by province, Afghanistan and Pakistan February 2013 to August 2014 Figure 24. WPV and cVDPV cases, Pakistan, 2013 and 2014 to date* Figure 25. WPV1 and cVDPV2 cases and environmental isolates by genetic cluster (WPV1) and emergence (cVDPV2), Pakistan, 12 August 2013 to 11 August 2014* Figure 26. WPV and cVDPV cases, FATA Sanctuary, 3 September 2013 to 2 September 2014* Page 100 GPEI Partner Status Report - 25 September 2014 Figure 27. WPV cases by week of onset and environmental surveillance results, FATA Sanctuary, Pakistan, 3 Sept 2013 – 2 Sept 2014* Figure 28. Proportion of Union Councils with LQAS survey results by SIA, FATA Sanctuary, Pakistan, Sept 2013 to Aug 2014 Figures 29. Proportion of NPAFP cases 6 to 35 months, by OPV status, FATA Sanctuary, Pakistan** Figure 30. WPV and cVDPV cases, KP Sanctuary, 3 September 2013 to 2 September 2014* Figure 31. WPV cases by week of onset and environmental surveillance results, KP Sanctuary, Pakistan, Sept 2013 to 2 Sept 2014* 3 Figure 32. Proportion of Union Councils with LQAS survey results by SIA, KP Sanctuary, Pakistan, Sept 2013 to Aug 2014 Figure 33. Proportion of NPAFP cases 6 to 35 months, by OPV status, KP Sanctuary, Pakistan** Figure 34. WPV & cVDPV cases and environmental surveillance results, Karachi Sanctuary, 3 September 2013 to 2 September 2014* Figure 35. WPV cases by week of onset and environmental surveillance results, Karachi Sanctuary, Pakistan, 3 Sept 2013 to 2 Sept 2014* Figure 36. Proportion of union councils with LQAS survey results* by SIA, Karachi Sanctuary, Pakistan, Sept to Aug 2014 Figure 37. Proportion of NPAFP cases 6 to 35 months, by OPV status, Karachi Sanctuary, Pakistan** Figure 38. WPV and cVDPV2 cases, Quetta Risk Area, 3 September 2013 to 2 September 2014* Figure 39. WPV cases by week of onset and environmental surveillance results, Quetta Risk Area, Pakistan 3 Sept 2013 to 2 Sept 2014* Figure 40. Proportion of Union Councils with LQAS survey results* by SIA, Quetta Risk Area, September 2013 to August 2014 Figure 41. Proportion of NPAFP cases 6 to 35 months, by OPV status, Quetta Risk Area, Pakistan** Figure 42. Key social characteristics, polio cases, 2013-14* Figure 43. Transit vaccination in Pakistan Figure 44. Summary of information on unavailable children, Pakistan February–June 2014 Figure 45. Location of areas where COMNet succeeded in negotiating access in South Waziristan Figure 46. I Inaccessible areas during the August 2014 SIA and 2014 WPV1 and cVDPV cases, Pakistan* Figure 47. WPV and cVDPV cases, Nigeria, 2013 and 2014 to date* Figure 48. Wild poliovirus type 1 (WPV1) by genetic cluster and circulating vaccine-derived poliovirus type 2 (cVDPV2) by emergence, Nigeria, 2013 and 2014 to date* Figure 49. WPV1 cases and environmental isolates by genetic cluster, Nigeria, 12 August 2013 to 11 August 2014* Figure 50. cVDPV2 in Nigeria and Niger by emergence, 12 August 2013 to 11 August 2014* Figure 51. WPV and cVDPV cases, North-Central Sanctuary, 3 September 2013 to 2 September 2014* Page 101 GPEI Partner Status Report - 25 September 2014 Figure 52. WPV and cVDPV cases by week of onset and environmental surveillance results, North-Central Sanctuary (Kano, Katsina, Jigawa, and Kaduna), Nigeria, 3 Sept 2013 to 2 Sept 2014* Figure 53. Proportion of LGAs with LQAS survey results by SIA, North-Central Sanctuary, Nigeria, Sept 2013 to Aug 2014 Figure 54. Proportion of NPAFP cases 6 to 35 months, by OPV status, North-Central Sanctuary, Nigeria** Figure 55. WPV and cVDPV cases, Northeast Sanctuary, 3 September 2013 to 2 September 2014* Figure 56. WPV and cVDPV cases by week of onset and environmental surveillance results, Northeast Sanctuary (Borno and Yobe), Nigeria, 3 Sept 2013 to 2 Sept 2014* Figure 57. Proportion of LGAs with LQAS survey results by SIA, Northeast Sanctuary, Nigeria, Sept 2013 to Aug 2014 Figure 58. Proportion of NPAFP cases 6 to 35 months, by OPV status, Northeast Sanctuary, Nigeria** Figure 59. WPV and cVDPV2 cases, Northwest Risk Area, 3 September 2013 to 2 September 2014* Figure 60. WPV and cVDPV cases by week of onset and environmental surveillance results, Northwest Risk Area (Sokoto and Zamfara), Nigeria 3 Sept 2013 to 2 Sept 2014* Figure 61. Proportion of LGAs with LQAS survey results by SIA, Northwest Risk Area, Nigeria, Sept 2013 to Aug 2014 Figure 62. Proportion of NPAFP cases 6 to 35 months, by OPV status, Northwest Risk Area, Nigeria** Figure 63. Trends in missed children, Kano state, Nigeria, Jun 2013-Jun 2014 Figure 64. Number of children vaccinated in specific demand-creation exercises, 10 high-risk states, Nigeria January to August 2014 Figure 65. Numbers of newborns registered and vaccinated by VCMs, Kano, May to August 2014 Figure 66. Number of children vaccinated at CMAM centers and number receiving the first OPV dose, 10 high-risk states, Nigeria, January to August 2014 Figure 67. Insecurity Levels in Nigeria, August 2014 Figure 68. Inaccessible areas, WPV1 cases, and the estimated number of children affected during the August 2014 SIA—Northeast Sanctuary, Nigeria Figure 69. Inaccessible Settlements in Borno and Yobe Provinces, Nigeria, August 2014 Figure 70 Six-month standard immunization indicators among children aged 6-35 months with AFP and annualized surveillance indicators by state, Nigeria, February 2013 to August 2014 Figure 71. WPV cases by week of onset in the Horn of Africa, 2013–2014 to date* Figure 72. WPV1 and cVDPV Cases in the Horn of Africa, 2013-2014 to date*. Figure 73. WPV cases and inaccessible children in Somalia in the August 2014 SIA Figure 74. Polio Campaign Awareness by Province/State, Horn of Africa Figure 75. WPV1 and cVDPV Cases in the Central Africa, 2013–2014 to date* Figure 76. Population movements within and from CAR as of 9 September Figure 77. WPV cases by week of onset in Central Africa, 2013-2014 to date* Page 102 GPEI Partner Status Report - 25 September 2014 Figure 78. WPV cases in Syria and Iraq, 2013-2014 to date* Figure 79. WPV and AFP cases by week of onset in Syria (n=36) and Iraq (n=2, WPV), 2013–2014 to date* Figure 80. Supplemental immunization activities in response to the Middle East outbreak, January–November 2014 Figure 81. Reasons for Non-Vaccination among Missed Children in Jordan, Syria, Lebanon and Iraq, December 2013–June 2014 Figure 82. Facsimile of Proposed Street Drawing to Raise Public Awareness about Polio in Syria Figure 83. AFP surveillance indicators at first administrative level, for AFP cases with onset 16 August 2013– 15 August 2014, 50 selected AFR, EMR and European Region countries Figure 84. Immunization status at first administrative level, for children 6-35 months of age with NPAFP cases with onset 16 August 2013–15 August 2014, 50 selected AFR, EMR and European Region countries Figure 85. OPV monthly demand vs. balance supplies: July 2014 to March 2015 (Projected) Figure 86: GPEI Cash Gap for 2014 as of July 2014 Page 103