Introduction to Course 9.04, Vision and Audition Vision: Peter H. Schiller Audition: Chris Brown Reading assignments Lectures Research reports Exams 1 Grade breakdown: Written report, vision Midterm exam Written report, audition Final exam = = = = 10% 25% 10% 55% (Vision, 15%, Audition, 40%) 2 Introductions 3 What aspects of visual processing are we trying to understand? The layout and organization of the visual system Adaptation and Color vision Movement processing Depth perception Object recognition Generation of visually guided eye movements 4 Schedule for the section on the visual system: Sep 9: The basic layout of the retina and the lateral geniculate nucleus Sep 11: The visual cortex Sep 16: The ON and OFF channels Sep 18: The midget and parasol channels Sep 23: Adaptation and color Sep 25: Depth perception Sep 30: Form perception Oct 2: Illusions and visual prosthesis Oct 7: The neural control of visually guided eye movements, 1 Oct 9: The neural control of visually guided eye movements, 2 Oct 16: Motion perception and pursuit eye movements Oct 21: Overview Oct 23: Midterm exam 5 Tools of the trade: Psychophysics Anatomy Electrophysiology Pharmacology Brain lesions Imaging Optogenetics 6 Psychophysics 7 Anatomy 11 Monkey brain central sulcus Central Sulcus V1 Principalis cipalis Lunate Arcuate lunate Image by MIT OpenCourseWare. 12 Fovea Optic nerve Human Retina Foveal cone density: 200,000/sqmm Foveal cone density: 200,000/sqmm 5 degrees out: 20,000/sqmm 5 degrees out: 20,000/sqmm 10 degrees out: 10,000/sqmm 10 degrees out: 10,000/sqmm Image by MIT OpenCourseWare. 13 Coronal section of monkey LGN Image removed from this file due to copyright restrictions. Please see lecture video or Figure 4A from Schiller, Peter H., Edward J. Tehovnik. "Visual Prosthesis." Perception 37, no. 10 (2008): 1529. 14 Golgi stain Procion Yellow labeling of a single cell Image removed from this file due to copyright restrictions. Please see lecture video or Figure RI0DVODQG5LFKDUG+ 7KHIXQFWLRQDODUFKLWHFWXUHRIWKHUHWLQD6FLHQWLILF $PHULFDQQR Image in public domain. 15 Electrophysiology 16 Pharmacology 19 Brain inactivation 21 Imaging 23 A B Figure 1B,D. Pfeuffer, Joseph, Hellmut Merkle, Michael Beyerlein, Thomas Steudel, and Nikos K. Logothetis. Anatomical and functional MR imaging in the macaque monkey using a vertical large-bore 7 Tesla setup." Magnetic resonance imaging 22, no. 10 (2004): 1343-1359. Courtesy of Elesevier Inc., http://www. sciencedirect.com. Used with permission. C D Image removed due to copyright restrictions. Please refer to lecture video. E Image removed due to copyright restrictions. Please refer to lecture video. Logothetis, N, Merkle H, Augath M, Trinath T, Ugurbil K. "Ultra high-resolution fMRI in monkeys with implanted RF coils." Neuron 35, no. 2 (2002): 227-242. Courtesy of Elesevier, Inc., http://www.sciencedirect.com. Used with permission. Optogenetics 25 MIT OpenCourseWare http://ocw.mit.edu 9.04 Sensory Systems Fall 2013 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.