GENOMICS MEETS GRID
INTRODUCTION
CHRIS THOMPSON
BACKGROUND
• SR 2000 - £120M NATIONAL PROGRAMME ON eSCIENCE
• £8M BBSRC PROGRAMME ON BIOINFORMATICS
AND e-SCIENCE IN 2001:
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5 PILOT PROJECTS (ca £5M)
ENABLING TECHNOLOGIES
SUMMER SCHOOL TRAINING
GRID SUPPORT CENTRE POST
GRID PILOT PROJECTS
• STERNBERG et al: A distributed pipeline for structure-based
proteome annotation using GRID technology
• SANSOM et al: A GRID database for biomolecular simulations
• NAVE et al: An e-Science resources for high through-put structural
biology
• BISBY: A problem-solving environment for global biodiversity:
prototype and demonstrator
• KIRKWOOD et al: Biology of Ageing: e-Science integration and
simulation system
• GODDARD et al: Grid-enabled modelling tools and databases for
neuroinformatics
GAPS
• Areas not supported through the e-Science
programme:
– Genomics
– Investigating Gene Function Initiative groups
– BBSRC-supported Institutes
• Grid Support Centre post - £200K over 3
years
SR2002 e-SCIENCE
• Up to £10M for a new BBSRC initiative
• Focus on integrating data from different sources to
inform about systems, organisms and their
interaction
• Build on existing e-Science activities
• Develop Grid technology for use in key areas not
covered by SR2000:
Genomics, IGF and the Institutes
AIMS OF THIS MEETING
• To educate the e-Science community about informatics
problems in genomics
• To inform the genomics community about what Grid
technology can offer
• To explore opportunities for collaboration
• To identify possible pilot projects
• To define how the Grid Support Centre can help
MEETING STRUCTURE 1
• Short presentations from genomics groups highlighting key
issues; Grid people to respond with first thoughts on how
their technology might help
• Plenary brainstorming; write on Post-its:
– Genomics informatics problems
– Possible Grid solutions
– Synergy with ongoing projects
Group them and identify breakout groups
MEETING STRUCTURE 2
• Breakout groups to explore opportunities and identify
some possible pilot projects – identify a rapporter
• Re-convene breakout groups the next day to prepare for
report-back
• Report-back on ideas generated
NEXT STEPS
• Develop collaborative groupings
• Seek input from Grid Support Centre
• Establish pilot projects; funding can be sought from
BBSRC responsive mode committees – Bioinformatics and
e-Science Cross Committee priority
• Develop bids for Sr2002 e-Science Initiative