Data Flows in Next Generation Sequencing : Replication, Durability and Metrology 16 March ‐ 17 March 2011 e‐Science Institute, 15 South College Street, Edinburgh Organisers: Dr Ruth McNally with Dr Adrian Mackenzie and Jennifer Tomomitsu, ESRC Cesagen, in association with the eSI Thematic Programme http://www.nesc.ac.uk/esi/events/1185/ Workshop Agenda (v1) WEDNESDAY ACTIVITIES SPEAKERS & LOCATION 1030 ‐ 1100 Registration with refreshments 1100 ‐ 1120 Welcome and introduction to the Workshop Dr Adrian Mackenzie and Dr Ruth McNally, ESRC Centre for Economic and Social Aspects of Genomics (Cesagen), Lancaster University 1120 ‐ 1200 Making a data archive for Next Generation Sequencing data Dr Guy Cochrane, leader of EBI European Nucleotide Archive (ENA) team 1200 ‐ 1220 Breakout 1. Global data maps Everyone 1220 ‐ 1315 Lunch 1315 ‐ 1330 Feedback on breakout 1 1330 ‐ 1440 The arc of an experiment at GenePool Quantities and qualities of Next Next Generation Sequencing data Professor Mark Blaxter, Principle Investigator at GenePool, NERC / MRC Next Generation Sequencing and Genomics Facility, Edinburgh University Dr Matt Clark, Head of Technology Development, BBSRC Genome Analysis Centre (TGAC), Norwich 1445 ‐ 1505 Breakout 2. Size, speed and cost Everyone 1505 ‐ 1525 Refreshment break 1525 ‐ 1540 Feedback on Breakout 2 1540 ‐ 1700 An Ensembl‐based miRNA pipeline Deploying Taverna workflows onto the Amazon Cloud to support Next Gen Seq post assembly annotation pipelines Dr Will Spooner, Technical Director, Eagle Genomics open‐ source bioinformatics services for genome content management Professor Carole Goble, co‐ Director of myGrid e‐Science Consortium, Manchester University 1700 ‐ 1725 Breakout 3. Workflows and pipelines Everyone 1725 ‐ 1745 Feedback on Breakout 3 Dinner at Hotel du Vin THURSDAY 0930 ‐ 0950 Welcome and introduction to Day Dr Adrian Mackenzie and Dr 2 of the Workshop Ruth McNally, ESRC Cesagen 0950 ‐ 1105 Data management for 1000 Genomes Project Processing Pipeline for 1000 Genomes Project Dr Laura Clarke, Technical leader for 1000 Genomes Project Data Management Group, EBI. Dr Shane McCarthy, co‐ developer of 1000 Genomes Project Data Processing Pipeline, Wellcome Trust Sanger Institute 1105 ‐ 1125 Refreshment break 1125 ‐ 1145 Breakout 4. Alignment, annotation and visualization Everyone 1145 ‐ 1200 Feedback on Breakout 4 1200 ‐ 1240 Sharing NGS data Dr Chris Taylor, Senior Software Engineer, European Bioinformatics Institute 1240 ‐ 1330 Lunch 1330 ‐ 1445 Roundtable discussion of emergent issues and future work/projects/research Everyone 1445 Afternoon tea, coffee and biscuits and departure