UCL INSTITUTE OF NEUROLOGY QUEEN SQUARE THE NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY QUEEN SQUARE LONDON WC1N 3BG QUEEN SQUARE PARKINSON’S DISEASE AND MOVEMENT DISORDERS GROUP FORUM GENETICS AND CELLULAR MECHANISMS OF PARKINSON’S DISEASE AND MOVEMENT DISORDERS COURSE Convenors: Prof John Hardy and Prof Kailash Bhatia Venue: Basement Lecture Theatre, 33 Queen Square Friday 8th April 1. Introduction and welcome John Hardy 11.00-11.15 2. Mendelian genes for parkinsonism and their phenotypes Nick Wood 11.15-11.45 3. Genetics of dystonia syndromes 11.45-12.15 Niccolo Mencacci 4. Genetic analysis of Dementia with Lewy Bodies Jose Bras 5. Lunch 12.15-12.45 12.45-14.00 6. Genome wide association studies in Parkinson’s disease Huw Morris 14.00-14.30 7. The pathology of parkinsonisms Janice Holton 14.30-15.00 8. The processes underlying synuclein toxicity Sonia Gandhi 15.00-15.30 9. Tea 10. Mitophagy failure as a cause of parkinsonism 15.30-15.45 Helene Plun Favreau 15.45-16.15 11. GBA dysfunction in parkinsonism Tony Schapira 12. Bioinformatic analysis of LRRK2 function Claudia Mazoni 16.45-17.15 13. Autophagy and parkinson’s disease Patrick Lewis 14. End of day 16.15-16.45 17.15-17.45 Saturday 9th April 1. Prediagnostic and risk phase and PREDICT-PD Annette Schrag 9.00-09.30 2. Clinicopathological cases Helen Ling 3. Coffee 9.30-10.00 10.00-10.15 4. New Treatments for PD Tom Foltynie 10.15-10.45 5. Synaptopathies in paroxysmal movement disorders Henry Houlden 10.45-11.15 6. Use of TMS in PD John Rothwell 11.15-11.45 7. Video session and concluding remarks Kailash Bhatia 11.45-12.30 8. Lunch at end of day Registration enquiries to Linda Taib (l.taib@ucl.ac.uk) UCL Participants – no fee. Others £20 – administrative fee for registration- (contact Linda Taib) Endorsed by the International Parkinson’s disease and MD society Supported by the International Parkinson and Movement Disorder Society. 2