Xiaosong Joy Jiang, M.D., Ph.D. Title Specialty Additional Phone Associate Adjunct Professor, Gastroenterology and Hepatology Research on Liver Disease Phone: 916-734-0329 Fax: 916-734-7846 Email Languages Education joyjiang@ucdavis.edu Cantonese, Chinese (Mandarin) M.D., Capital Medical University, Beijing China 1998 M.S., Neurobiology, Hong Kong University of Science and Techolology, Hong Kong China 2003 Ph.D., Nutritional Biology, UC Davis, Davis CA 2012 Internships Internal Medicine, Capital Medical University - Chaoyang Hospital, Beijing China 1997 Residency Internal Medicine, Peking University - Shougang Hospital, Beijing China 1998 Honors and Awards Select Recent Publications Richard C. Woodard Research Award, Internal Medicine , UC Davis, 2013 Bettaieb, A.*, Jiang, J.X.*, Sasaki, Y., Chao, T.I., Kiss, Z., Chen, X., Tian, J., Katsuyama, M., YabeNishimura, C., Xi, Y., Szyndralewiez, C., Schröder, K., Shah, A., Brandes, R.P., Haj, F.G. and Török, N.J. Hepatocyte NADPH oxidase 4 regulates stress signaling, fibrosis, and insulin sensitivity during development of steatohepatitis in mice. Gastro. pii: S0016-5085(15)00509-0. doi: 10.1053 /j.gastro. 2015.04.009. (IF:13.926) (*equal contribution) Jiang, J.X. And Török, N.J. MLK3 as a regulator of disease progression in NASH. Liver Int. 2014 DOI: 10.1111/liv. 12556. Jiang, J.X. and Török, N.J. Liver injury and the activation of hepatic myofibroblasts. Curr. Pathobiol. Rep. 2013; 1(3): 215-223. Jiang, J.X., Chen, X., Fukada, H., Serizawa, N., Devaraj, S., and Török, N.J. Advanced glycation end products induce inflammatory and fibrogenic activity in NASH by modulating the TNF Xiaosong Joy Jiang, M.D., Ph.D. converting enzyme activity. Hepatol. 2013; 58(4):1339-1348. Medici, V., Shibata, N., Kharbanda, K.K., LaSalle, J.M., Woods, R., Liu, S., Engelberg, J., Cardiff, R. D., Havel, P.J., Devaraj, S., Török, N.J., Jiang, J.X., Lönnerdal, B., Kim, K., Halsted, C.H. Wilson disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. Hepatol. 2012;57(2):555-565. Jung, C.J., Iyengar, S., Blahnik, K.R., Jiang, J.X., Tahimic, C., Török, N.J., de Vere White, R.W., Farnham, P.J., Zern, M. Human ESC Self-renewal Promoting microRNAs Induce Epithelial– Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGF Tumor Suppressor Signaling Pathways. Mol Cancer Res. 2012; 10(7):979-991. Jiang, J.X., Chen, X., Serizawa, N., Szyndralewiez, C., Page, P., Schröder, K., Brandes, R.P., Devaraj, S., Török, N.J. Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo. Free Radic Biol Med. 2012;53(2):289-296. Jiang, J.X., Chen, X., Hsu, D., Baghy, K., Serizawa, N., Scott, F., Takada, Y., Takada, Y., Fukada, H., Chen, J., Devaraj, S., Adamson, R., Liu, F.T. and Török, N.J. Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo. Am. J. Physiol. Gastrointest. Liver Physio. 2012;302(4): G439-446. Jung, C.J., Iyengar, S., Blahnik, K.R., Ajuha, T.P., Jiang, J.X., Farnham, P.J., Zern, M. Epigenetic modulation of miR-122 facilitates human embryonic stem cell selfrenewal and hepatocellular carcinoma proliferation. PLoS One 2011;6(11):e27740. Medici, V., Ali, M., Seo, S., Aoki, C., Rossaro, L., Kim, K., Fuller, W., Vidovszky, T., Smith, W., Jiang, J.X., Maganti, K., Havel, P.J., Kamboj, A., Ramsamooj, R. and Török, N.J. Increased Soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver Xiaosong Joy Jiang, M.D., Ph.D. disease. Obesity. 2010;18(12):2268-2273. © 2016 UC Regents