Charles S. DeCarli, M.D.
Clinical Interests
Charles DeCarli, MD, is Professor of Neurology at the University of California in Davis, California.
He is the Director of the Alzheimer’s Disease Center, a United States National Institutes of Health
funded Alzheimer’s research center. He is also Director of the Imaging of Dementia and Aging
(IDeA) laboratory.
His research focuses on using advanced structural and functional brain imaging to study normal
aging, mild cognitive impairment and dementia and the role of genetics, cerebrovascular and
Alzheimer’s disease on these processes.
He is a recipient of the J. Allyn Taylor International Prize in Medicine—Imaging of the Aging Brain
in recognition of his work. In addition, Dr. DeCarli is the Editor-in-Chief of Alzheimer Disease and
Associated Disorders, an international journal of AD research.
Title
Director of Alzheimer's Disease Center
Professor
Specialty
Neurology
Department
Neurology
Division
Neurology
Address/Phone
Lawrence J. Ellison Ambulatory Care Center, Neurology, 4860 Y St. Suite 0100 Sacramento, CA
95817
Phone: 916-734-3588
Additional Phone
Phone: 916-734-5496
Physician Referrals: 800-4-UCDAVIS (800-482-3284)
Education
M.D., George Washington University, Washington, D.C., 1982
B.S., UC Santa Barbara, Santa Barbara, California, 1978
Residency
George Washington University Medical Center, Washington, District of Columbia, 1982-84
Strong Memorial Hospital, Rochester, New York, 1984-87
Fellowships
Board Certifications
Professional Memberships
National Institute on Aging, Bethesda, Maryland, 1987-89
American Board of Neurology and Psychiatry, 1991
American Academy of Neurology
American Association for the Advancement of Science
Charles S. DeCarli, M.D.
American Medical EEG Association
Society for Neuroscience
Select Recent Publications
He J, Carmichael O, Fletcher E, Singh B, Iosif AM, Martinez O, Reed B, Yonelinas A, Decarli C.
Influence of functional connectivity and structural MRI measures on episodic memory. Neurobiol
Aging. 2012 Jan 26. [Epub ahead of print]
Joshua C Bis, Charles DeCarli, Albert Vernon Smith, Fedde van der Lijn, Fabrice Crivello, Myriam
Fornage, Stephanie Debette, Joshua M Shulman, Helena Schmidt, Velandai Srikanth, Maaike
Schuur, Lei Yu, Seung-Hoan Choi, Sigurdur Sigurdsson, Benjamin F J Verhaaren, Anita L
DeStefano, Jean-Charles Lambert, Clifford R Jack Jr, Maksim Struchalin, Jim Stankovich, Carla A
Ibrahim-Verbaas, Debra Fleischman, Alex Zijdenbos, Tom den Heijer, Bernard Mazoyer, Laura H
Coker, Christian Enzinger, Patrick Danoy, Najaf Amin, Konstantinos Arfanakis, Mark A van
Buchem, Renée F A G de Bruijn, Alexa Beiser, Carole Dufouil, Juebin Huang, Margherita Cavalieri,
Russell Thomson, Wiro J Niessen, Lori B Chibnik, Gauti K Gislason, Albert Hofman, Aleksandra
Pikula, Philippe Amouyel, Kevin B Freeman, Thanh G Phan, Ben A Oostra, Jason L Stein, Sarah E
Medland, Alejandro Arias Vasquez, Derrek P Hibar, Margaret J Wright, Barbara Franke, Nicholas G
Martin, Paul M Thompson, Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA)
Consortium, Michael A Nalls, Andre G Uitterlinden, Rhoda Au, Alexis Elbaz, Richard J Beare, John
C van Swieten, Oscar L Lopez, Tamara B Harris, Vincent Chouraki, Monique M B Breteler, Philip L
De Jager, James T Becker, Meike W Vernooij, David Knopman, Franz Fazekas, Philip A Wolf, Aad
van der Lugt, Vilmundur Gudnason, W T Longstreth Jr, Matthew A Brown, David A Bennett,
Cornelia M van Duijn, Thomas H Mosley, Reinhold Schmidt, Christophe Tzourio, Lenore J Launer,
M Arfan Ikram, Sudha Seshadri the Cohorts for Heart and Aging Research in Genomic
Epidemiology (CHARGE) Consortium. Nature Genetics Published online: 15 April 2012 doi:
10.1038/ng.2237.
M Arfan Ikram, Myriam Fornage, Albert V Smith, Sudha Seshadri, Reinhold Schmidt, Stéphanie
Debette, Henri A Vrooman, Sigurdur Sigurdsson, Stefan Ropele, H Rob Taal, Dennis O MookKanamori, Laura H Coker, W T Longstreth Jr, Wiro J Niessen, Anita L DeStefano, Alexa Beiser,
Alex P Zijdenbos, Maksim Struchalin, Clifford R Jack Jr, Fernando Rivadeneira, Andre G
Uitterlinden, David S Knopman, Anna-Liisa Hartikainen, Craig E Pennell, Elisabeth Thiering, Eric
A P Steegers, Hakon Hakonarson, Joachim Heinrich, Lyle J Palmer, Marjo-Riitta Jarvelin, Mark I
McCarthy, Struan F A Grant, Beate St Pourcain, Nicholas J Timpson, George Davey Smith, Ulla
Sovio, Mike A Nalls, Rhoda Au, Albert Hofman, Haukur Gudnason, Aad van der Lugt, Tamara B
Harris, William M Meeks, Meike W Vernooij, Mark A van Buchem, Diane Catellier, Vincent W V
Jaddoe, Vilmundur Gudnason, B Gwen Windham, Philip A Wolf, Cornelia M van Duijn, Thomas
Charles S. DeCarli, M.D.
H Mosley Jr, Helena Schmidt, Lenore J Launer, Monique M B Breteler, Charles DeCarli, the
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Nature
Genetics Published online: 15 April 2012 doi:10.1038/ng.2245
Maillard P, Fletcher E, Harvey D, Carmichael O, Reed B, Mungas D, Decarli C. White Matter
Hyperintensity Penumbra. Stroke. 2011 Jun 2. [Epub ahead of print]
Mayda ABV, Westphal A, Carter CS, DeCarli C. Late life cognitive control deficits are accentuated
by white matter disease burden. Brain. 2011 Jun;134(Pt 6):1673-83
Debette S, Seshadri S, Beiser A, Au R, Himali JJ, Palumbo C, Wolf PA, Decarli C. Midlife vascular
risk factor exposure accelerates structural brain aging and cognitive decline. Neurology. 2011 Aug
2;77(5):461-8.
Gorelick PB, Scuteri A, Black SE, DeCarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S,
Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC,
Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Seshadri S; on behalf of the
American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on
Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on
Cardiovascular Surgery and Anesthesia. Vascular Contributions to Cognitive Impairment and
Dementia: A Statement for Healthcare Professionals From the American Heart
Association/American Stroke Association. Stroke. 2011 Sep;42(9):2672-713.
Reed BR, Mungas D, Farias ST, Harvey D, Beckett L, Widaman K, Hinton L, Decarli C. Measuring
cognitive reserve based on the decomposition of episodic memory variance. Brain. 2010 Jun 30.
133(pt8): 2196-209.
GuoZ, Gupples LA, Kurz A, Auerbach S, Volicer L, Chui H, Green RC, Sandovnic AD, Duara R,
DeCarli C, Johnson K, Go RC, Growdon JH, Haines JL, Kukull WA, Farrer LA. Head injury and the
risk of Alzheimer disease in the MIRAGE study. NEUROLOGY 2000;54:1316-1
Geroldi C, Laakso MP, DeCarli C, Beltramello A, Bianchetti A, Soininen H, Trabuchhi M, Frisoni
GB. Apolipoprotein E Genotype and hippocampal asymmetry in Alzheimer's disease: A volumetric
MRI study. JOURNAL OF NEUROLOGY, NEUROSURGERY & PSYCHIATRY 2000;68:
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