Clinical Interests
Title
Specialty
Division
Center/Program Affiliation
Address/Phone
Breast and lung pathology. Breast cancer early diagnosis.
Assistant Professor
Pathology and Laboratory Medicine, Pathology - Anatomic
Pathology
UC Davis Comprehensive Cancer Center
Pathology Building, 4400 V St. Sacramento, CA 95817
Phone: 916-734-2525
Residency
State University of NY-Upstate Medical University, NY, 2006-2010
University of Michigan, MI, 2010-11
Women and Children Hospital, Shenyang, Liaoning, 1989-94
Fellowships
The University of Chicago, Chicago, IL, 1997-98
The University of Pennsylvania-The Winstar Institute, PA, 1999
University of Michigan, MI, 1999-06
Board Certifications
Professional Memberships
American Board of Pathology, 2010
CAP
USCAP
Select Recent Publications
Huang W, Zhang Y, Varambally S, Chinnaiyan AM, Banerjee M, Merajver SD, Kleer CG. Inhibition
of CCN6 (Wnt-1-induced signaling protein 3) down-regulates E-cadherin in the breast epithelium
through induction of snail and ZEB1. Am J Pathol. 2008;172(4):893-904.
Kleer CG, Zhang Y, Merajver SD. CCN6 (WISP3) as a New Regulator of the Epithelial Phenotype in
Breast Cancer. Cells Tissues Organs. 2007; 185, No. 1-3:95-99.
Zhang Y, Pan Q, Zhong, H, Merajver, SD, Kleer CG. Inhibition of CCN6 (WISP3) Expression
Promotes Neoplastic Transformation and Enhances the Effects of IGF-1 on Breast Epithelial Cells.
Breast Cancer Research 2005 7:R1080-1089.
Kleer CG, Zhang Y, Pan Q, Gallagher G, Wu M, Wu ZF, Merajver SD. WISP3 and RhoC guanosine
triphosphatase cooperate in the development of inflammatory breast cancer. Breast Cancer Res.
2004;6(1):R110-5.
Kleer CG, Zhang Y, Pan Q, Merajver SD. WISP3 (CCN6) is a secreted tumor-suppressor protein
that modulates IGF signaling in inflammatory breast cancer. Neoplasia. 2004;6(2):179-85.
Kleer CG, Zhang Y, Pan Q, van Golen KL, Livant D,Wu ZF, Merajver SD. WISP3 is a novel tumor
suppressor gene of inflammatory breast cancer. Oncogene. 2002;21(20):3172-80.
Kleer CG, van Golen KL, Zhang Y, Wu ZF, Rubin MA, Merajver SD Characterization of RhoC
expression in benign and malignant breast disease: A potential new marker for small breast
carcinomas with metastatic ability. Am J Pathol. 2002;160(2):579-84.
Chien K.S.E., Zhang Y., Furuta H., Hara M. : Expression of ATP-sensitive potassium channel
subunits in female rat reproductive tissues: Overlapping distribution mRNAs for weak inwardly
rectifying potassium channel subunit 6.1 and Sur 2. Am J Obstet Gynecol 1999, 180(5): 11211126.
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