Andrew Ishida, Ph.D.
Clinical Interests
Our laboratory studies ion currents and action potentials in mammalian retinal ganglion cells. We
use electrophysiological, immunohistochemical, and biochemical methods to investigate how and
why retinal ganglion cell spiking changes between night and daytime vision.
Research/Academic Interests
Dr. Ishida's research interests include:
1) Retinal ganglion cell excitability.
2) Modulation of ion currents and action potentials.
3) Light-activated protein kinases.
Title
Specialty
Department
Division
Education
Fellowships
Professor
Ophthalmology
Ophthalmology and Vision Science
Ophthalmology
Ph.D., UCLA, Los Angeles CA 1981
Ecole Normale Superieure, Paris, 1983-1985
National Institute for Physiological Sciences, Okazaki, 1981-1983
Professional Memberships
American Physiological Society
Association for Research in Vision and Ophthalmology
Society for Neuroscience
Honors and Awards
ASUCD Excellence in Education Award (College of Biological Sciences), 2012
Plum Foundation Award 2009, 2010
Japan Society for the Promotion of Science Fellowship, 1997
Fondation pour la Recherche Medicale Foreign Research Fellowship (Paris, France), 1984
NIH National Research Service Award 1979, 1982, 1983
Select Recent Publications
Stradleigh TW, Greenberg KP, Partida GJ, Pham A, Ishida AT. Moniliform deformation of retinal
ganglion cells by formaldehyde-based fixatives. J Comp Neurol. 2015 Mar 1;523(4):545-64.
Ogata G, Stradleigh TW, Partida GJ, Ishida AT. Dopamine and full-field illumination activate D1
and D2-D5-type receptors in adult rat retinal ganglion cells. J Comp Neurol. 2012 Dec 1;520(17):
Andrew Ishida, Ph.D.
4032-49.
Partida GJ, Stradleigh TW, Ogata G, Godzdanker I, Ishida AT. Thy1 associates with the cation
channel subunit HCN4 in adult rat retina. Invest Ophthalmol Vis Sci. 2012 Mar 26;53(3):1696703.
Stradleigh TW, Ogata G, Partida GJ, Oi H, Greenberg KP, Krempely KS, Ishida AT. Colocalization
of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion
cells. J Comp Neurol. 2011 Sep 1;519(13):2546-73.
Hayashida Y, Rodríguez CV, Ogata G, Partida GJ, Oi H, Stradleigh TW, Lee SC, Colado AF, Ishida
AT. Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation. J
Neurosci. 2009 Nov 25;29(47):15001-16.
Lee SC, Ishida AT. Ih without Kir in adult rat retinal ganglion cells. J Neurophysiol. 2007 May;97
(5):3790-9.
Partida GJ, Lee SC, Haft-Candell L, Nichols GS, Ishida AT. DARPP-32-like immunoreactivity in AII
amacrine cells of rat retina. J Comp Neurol. 2004 Dec 13;480(3):251-63.
Hayashida Y, Ishida AT. Dopamine receptor activation can reduce voltage-gated Na+ current by
modulating both entry into and recovery from inactivation. J Neurophysiol. 2004 Nov;92(5):313441.
Lee SC, Hayashida Y, Ishida AT. Availability of low-threshold Ca2+ current in retinal ganglion
cells. J Neurophysiol. 2003 Dec;90(6):3888-901.
Andrew Ishida, Ph.D.
Vaquero CF, Pignatelli A, Partida GJ, Ishida AT. A dopamine- and protein kinase A-dependent
mechanism for network adaptation in retinal ganglion cells. J Neurosci. 2001 Nov 1;21(21):862435.
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