Ruth Welti
Division of Biology
Kansas State University
Manhattan, KS 66506
Personal information
Born: October 8, 1954, Hartford, Connecticut
Office: (785) 532-6241
Email: welti@ksu.edu
Web page: http://www.k-state.edu/biology/faculty_pages/welti.html
Education
B.S. with Honors in Chemistry, University of Connecticut, Storrs, CT, 1976
Ph.D., Biological Chemistry, Washington University in Saint Louis, St. Louis, MO, 1982 (Advisor:
David F. Silbert)
Postdoctoral Fellow, Department of Biochemistry, Kansas University Medical Center, Kansas City,
KS, 1982-1984 (Advisor: George M. Helmkamp, Jr.)
Appointments
Division of Biology, Kansas State University, University Distinguished Professor, 2012Division of Biology, Kansas State University, Professor, 2005Director, Kansas Lipidomics Research Center, 2004-present
Director, Kansas Lipidomics Research Center Analytical Laboratory, 2003-present
Division of Biology, Kansas State University, Associate Professor, 1992-2005
Mass Spectrometry Laboratory, University of Kansas, Visiting Faculty, Fall 2001
Department of Biochemistry, University of Illinois at Urbana-Champaign, Visiting Faculty 1992-1993
Division of Biology, Kansas State University, Assistant Professor, 1985-1992
Department of Biochemistry, Kansas University Medical Center, Research Assistant Professor,
1984-1985; Postdoctoral Fellow, 1982-1984
Department of Biological Chemistry, Washington University School of Medicine, Research technician,
1976-1977
Honors
American Heart Association, Kansas Affiliate, Inc. Postdoctoral Fellowship, 1982-1984
National Science Foundation Career Advancement Award, 1992-1993
National Science Foundation Kansas State University ADVANCE Career Advancement Award, 20042005 and 2007-2008
Kansas Technology Enterprise Corporation Scholar, 2006
Sigma Xi, Kansas State University Chapter, Outstanding Senior Scientist Award, 2008
University Distinguished Professor, Kansas State University, 2012
AAAS (American Association for Advancement of Science) Fellow, Section on Biological Sciences,
2012
Pearl Award (an award for excellence in science, technology, engineering, or math), Girl Scouts of NE
Kansas and NW Missouri, 2013
Fields of research interest
Lipid and membrane biochemistry
Analysis of lipids by traditional and mass spectrometric methods
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Lipids in plant stress responses
Lipids in metabolic signaling cascades
Membership in academic societies
American Society for Biochemistry and Molecular Biology
American Society for Mass Spectrometry
American Oil Chemists Society
American Society of Plant Biologists
American Society for the Advancement of Science
Editorial boards
Journal of Biological Chemistry (2009-present)
Frontiers in Plant Physiology (review editorial board, 2011- present)
Frontiers in Technical Advances in Plant Science (review editorial board, 2011- present)
Frontiers in Plant Metabolism and Chemodiversity (associate editorial board, 2011- present)
Plant Metabolic Network (2011 – present)
Grant review and other granting agency panels
American Heart Association, Kansas Affiliate, Inc., Peer review committee (1992-1994)
American Heart Association, Kansas Affiliate, Inc., Research committee (1994-1998)
American Heart Association, Kansas Affiliate, Inc., “Ad hoc committee to revise application forms”
(1996)
NIH, National Institutes of Diabetes and Digestive and Kidney Diseases: Special study section on
polycystic kidney disease (1995)
NIH Special Emphasis Panel: Mathematical modeling of gene expression and metabolism (2005)
NIH site visit panel, Multiple Isotope Mass Spectrometry imaging facility at Brigham & Women's
Hospital, Cambridge, MA (2007)
NIH Special Review Committee for Program Project Grant evaluation (2007)
NIH Review panel for R13 (grants to fund conferences) proposals (real-time online meeting and
review, 2008)
National Science Foundation Metabolic Biochemistry Panel, Arlington, VA (2009)
NIH study section guest reviewer (phone meeting, 2010)
National Science Foundation and Japan Science and Technology Agency Workshop: “Identifying
Potential Collaborative Research Opportunities in Metabolomics”, Davis, CA (2010)
National Science Foundation, Molecular and Cellular Biosciences virtual full panel (2012)
NIH virtual site visit panel, Multiple Isotope Mass Spectrometry imaging facility at Brigham &
Women's Hospital, Cambridge, MA (2013)
Grant proposal reviews (written)
American Cancer Society
Biotechnology and Biological Sciences Research Cluster (BBSRC), UK
Canada Foundation for Innovation (CFI) Leaders Opportunity Fund (LOF)
Cancer Research UK Programme Grant Review
Council for the Earth and Life Sciences of NOW (Netherlands Organisation for Scientific Research)
Kansas Agricultural Experiment Station
Kentucky Science & Engineering Foundation
Missouri Review Board
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NSF
Netherlands Organisation for Scientific Research
Research Grants Council (RGC) of Hong Kong
USDA
Vanderbilt Diabetes Center DRTC Pilot and Feasibility Program
Wellcome Trust
External Reviewer for Promotion and/or Tenure
Iowa State University
Oklahoma State University
St. John’s University
University of California, Davis
University of New Mexico
University of North Texas
Virginia Tech
Referee for Journals (Since 1993)
American Journal of Potato Research
Analytical Biochemistry
Analytical Chemistry
Annals of Applied Biology
Archives of Biochemistry
Biochemistry
Biochimica et Biophysica Acta
Biophysical Journal
Cellular and Molecular Biology
Chemistry & Biology
Chemistry and Physics of Lipids
Current Opinion in Plant Biology
Crop Science
Frontiers in Plant Physiology
Frontiers in Plant Science
Investigative Opthamology and Visual Science
Journal of the American Oil Chemists Society
Journal of the American Society for Mass Spectrometry
Journal of Applied Phycology
Journal of Biological Chemistry
Journal of Chromatography B
Journal of Integrative Plant Biology
Journal of Lipid Research
Journal of Plant Interactions
Journal of Plant Physiology
Lipids
Mass Spectrometry Reviews
Membrane Molecular Biology
Plant and Cell Physiology
The Plant Journal
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Plant Methods
Plant Molecular Biology
Plant Physiology and Biochemistry
Plants (MDPI Open Access journal)
Phytochemistry
Planta
Plant Physiology
PLoS ONE
Proceedings of the National Academy of Sciences, USA
Rapid Communications in Mass Spectrometry
Textbook and book reviews
Fitzgerald Science Press
Freeman/Scientific American, Inc.
John Wiley & Sons (Concept Connections)
Wadsworth
Chapter for a book edited by Hajime Wada and Norio Murata
Invited seminars from 2002
Kansas State University, Department of Biochemistry (2002)
Kansas State University, Division of Biology (2003)
Kansas State University, Division of Biology (2004)
Donald Danforth Plant Science Center, St. Louis, MO (2005)
University of Chicago, Department of Opthlamology (2005)
Johns Hopkins University Medical School, Dept. of Biochemistry (2005)
University of North Texas, Dept. of Biological Sciences (2005)
St. Louis University School of Medicine, Dept. of Biochemistry and Molecular Biology (2006)
University of Kansas Medical Center, Dept. of Physiology (2007)
Oklahoma State University, Dept. of Biochemistry (2007)
Michigan State University, J. Ohlrogge and M. Pollard group, Dept. of Plant Biology (2008)
Kansas State University, Sigma Xi Outstanding Senior Scientist talk (2009)
Iowa State University, Bioinformatics group (2009)
Texas Tech, Dept. of Chemistry and Biochemistry (2009)
University of Louisville, Dept. of Chemistry (2009)
Langston University, Oklahoma, Dept. of Biology (2009)
Kansas State University, Dept. of Diagnostic Medicine and Pathobiology (2009)
University of Nebraska, Department of Biochemistry (2010)
University of Iowa, Department of Anatomy and Cell Biology (2011)
University of Missouri-Columbia, Interdisciplinary Plant Biology Group (2011)
Samuel Roberts Noble Foundation, Plant Biology (2012)
Washington State University, Institute of Biological Chemistry (2012)
Kansas State University, Department of Biochemistry (2013)
Georgetown University (anticipated 2014)
University of Missouri-Columbia (anticipated 2014)
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Invited oral presentations at meetings from 2001
National Plant Lipid Cooperative, South Lake Tahoe, CA (2001)
American Oil Chemists Society annual meeting, Kansas City, Missouri (award for “Outstanding Paper
Presentation”) (2003)
Noble Foundation Metabolomics Conference, Ardmore, Oklahoma (2003)
KBRIN Student Symposium (key-note lecture), KSU Alumni Center (2004)
COBRE-sponsored symposium, “What’s hot?”, University of Kansas (2004)
Kansas Lipidomics Research Center workshop, KSU Alumni Center (2004)
3rd International Metabolomics conference, Iowa State University (2004)
Kansas Statewide EPSCoR meeting, KSU Alumni Center (2004)
International Conference on Plant-Mediated Lipid Signaling, Raleigh, NC (2005)
American Oil Chemists annual meeting, St. Louis, MO (2006)
17th International Symposium on Plant Lipids, East Lansing, MI (2006)
Kansas Lipidomics Research Center Annual Meeting, Kansas State University Student Union (2006)
Functional Genomics Consortium Fall Workshop, Kansas State University (2007)
Functional Genomics Consortium Fall Workshop, Kansas State University (2008)
American Society for Mass Spectrometry Sanibel conference on Lipidomics, St. Petersburg Beach,
Florida (2009)
Gordon Conference on Plant Lipids: Structure, Metabolism & Function (Discussion Leader),
Galveston, TX (2009)
Metabolomics Mini-Symposium, Noble Foundation, Ardmore, OK (2009)
Great Plains Plant Lipidomics Conference, Denton, TX (2010)
Gordon Conference on Plant Lipids: Structure, Metabolism & Function (Discussion Leader),
Galveston, TX (2011)
Functional Genomics Spring Symposium, Kansas State University (2011)
American Oil Chemists annual meeting, Cincinnati, OH (2011)
LIPID MAPS annual meeting, San Diego, CA (2012)
Meeting Organization
Co-organizer of American Oil Chemists Society “Analytical” section on Mass Spectrometry of Lipids,
Salt Lake City, UT (2005)
Organizer of Kansas State University Functional Genomics Consortium Fall Workshops (2006, 2007,
2008, 2009, 2010)
Organizer of Kansas State University Functional Genomics Consortium Spring Symposia (2007, 2008,
2009, 2010, 2011)
Member of the committee to enhance diversity at the meeting, select speakers, and choose travel award
recipients, Gordon Conference on Plant Lipids, Galveston, TX (2009)
Vice-Chair of Gordon Research Conference on Plant Lipids, Galveston, TX (2011)
Chair of Gordon Research Conference on Plant Lipids, Galveston, TX (2013)
Consultant
Scientific consultant (unpaid) for Global Lipidomics LLC
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Contracts or other agreements for lipid analysis (by Kansas Lipidomics Research Center; Welti,
Director)
BASF
BD Biosciences
Boehringer-Ingelheim
Dupont
Martek
Pioneer Hi-Bred International, Inc.
Sime Darby Technology Centre
US EPA
National Resource Council of Canada
Welti Lab Research Trainees
Undergraduates in Welti lab (1985-current, alphabetical)
Morgan Ambruster
Kristi Armstrong
Brittanie Atkinson (SUROP student from Langston University)
Robert Avery
James Barrick
Danny Bartlett
Ethan Baughman
Joe Bloomfield
Danielle Boyer (summer student, undergraduate at Mount Union College)
Cynthia Buel
Chad Bulleigh
Ariel Burns
Christen Buseman
Taran Carlisle
Shad Chandler
Carmen Chase
Devon Claycamp
Scott Coates
Jamie Crane
Marley Crusch
Nicole Delimont
Christopher Ecklund
Samantha Elledge
Gloria Fernandez
Brigid Flynn
Susan Goedecke Larson
Nicole Haen
Melissa Harrison
Samuel Honey
Ana Hooker
David Hwang
Levi Kinderknecht
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Jacqueline Kitchen
Darren Klish
Sandra Koo (high school student)
Brett Kidd
Bharath Krishnamoorthi (summer student from KU)
Jonathan Kurche
Abbey Laughlin
Kaleb Lowe (summer student from Vanderbilt U.)
Sara Maatta (high school student and summer student from Stanford U.)
Lee Martin
Tara Thacker McConkey
Dedan McEllhiney
Astyn Miller
Elizabeth Miller
Katie Mosier
Elaina Murray
Tamara Nun
Nathan Pavlovic (summer student from Grinnell College)
Neema Prakash
Daniel Prohaska
Gina Ragusa
Anita Ranhotra
Dow Richards
Melanie Riley
Erica Ring
Gerard Ryan
Mohammed Sbeih
Brad Scheu
Rachel Schulter
Roshni Singh (high school student)
Madison Sparks
Michelle Thilges
Travis Torres
Mark Vacca
Craig Whitefield
David Whitmer (summer student from Fort Hays State U.)
Hollie Wickham
Jeremy Wiltz
Kelly Zachareisen
Non-degree graduate students
Kathleen Clauss (visiting from Institute of Plant Biochemistry, Halle, Germany, 2009)
Alfredo Cruz (visiting from Center for Research and Advanced Studies of the National Polytechnic
Institute, Irapuato, Mexico, 2005)
Suha Saleh (special student)
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Ashutosh Singh (visiting from Jahwaharlal Nehru University, New Delhi, India, on an American
Society of Microbiology Fellowship, 2009)
Maria Zavodszky (rotation)
Masters students
Amy Garner (not completed)
Ana Hooker (not completed)
Mark Vacca (M.S., 1998)
Ph.D. students
Norma Flores (Ph.D., 1998, U. Philippines; completed Ph.D. research in Welti lab under an exchange
agreement)
Christopher Zien (Biology, 2000)
Maoyin Li (Biochemistry, Co-major professor with Xuemin Wang, 2005)
Hieu Sy “Danny” Vu (Biology, 2007-current)
Postdoctoral scholars
Xuesheng Xu (1992-1994) Currently: Assistant Professor, University of Colorado Health Sciences
Center
Jian Zhao (Co-advised with Xuemin Wang, Biochemistry, 2002-2004); Currently: Postdoctoral fellow,
Samuel Roberts Noble Foundation
Shivakumar Pattada Devaiah (Co-advised with Xuemin Wang, Biochemistry, 2002-2005), Currently:
Postdoctoral fellow: Arkansas State University
Steven Wynn Esch (2006-2007); Currently: Unknown
Giorgis Isaac (Mezengie) (2005-2008); Currently: Research Chemist, Waters Corporation
Richard Jeannotte (2005-2011); Currently: Research Associate, University of California-Davis
Sunitha Shiva (2010-current)
Thilani Samarakoon (2011-2012)
Visiting scientists
Chien-an “Andy” Hu, University of New Mexico (2008)
Walter Kpikpi, University for Development Studies, Navrongo Campus, Ghana (2008)
Malathi Srinivasan, CSIR-CIMAP, India (2012)
Vanina Gisela Lopez, National Laboratory (Mass Spectrometry), Buenos Aires, Argentina (2013)
Mentor for junior colleagues
Rachel Zufferey, Department of Biochemistry (mentor for Cancer Therapeutics NIH COBRE Award at
U. of Kansas; B. Timmermann, PI)
Carolyn Ferguson, Division of Biology (Kansas State NSF ADVANCE Career Award mentor)
Kathrin Schrick, Division of Biology (Division of Biology mentoring program)
Timothy Durrett, Department of Biochemistry (mentor for NSF EPSCoR-funded project)
Courses taught (1993 to present):
Principles of Biology (BIOL 198): 1993-2000, 2002, 2004-2013
Cell Biology (BIOL 541): 1994-2004
Biomembranes (BIOL 719; formerly BIOL 697/890): 1994, 1996, 1998, 2000, 2002, 2004
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Advanced Cell Biology (BIOL 707; formerly BIOL 697/890): 2000, 2002-2006
Molecular Biology of Cellular Membranes (BIOL 855; guest lectures): 1993-2000, 2002-2006, 2010
Biochemistry 2 (BIOCH 765; guest lectures): 2005, 2010, 2011
Lipids (BIOCH 910; guest lectures): 1993, 1995, 1997, 1999, 2007
Biochemistry of Cellular Regulation (BIOCH 935; guest lecture): 2005
Advising (year: number of students in fall, number of students in spring):
1993: 7; 1994: 7, 10; 1995: 9, 13; 1996: 9, 14; 1997: 17, 19; 1998: 17, 23; 1999: 20, 31; 2000: 32, 29;
2001: 32, 30; 2002: 30, 26; 2003: 22, 21; 2004: 18, 17; 2005: 13, 13; 2006: 14, 12; 2007: 12, 11; 2008:
9, 6; 2009: 6, 6; 2010: 12, 14; 2011: 14, 15; 2012: 14, 20; 2013: 19; 20.
Graduate supervisory committees (other than my own students):
Ph.D. committees: Asim Abdel Mageed (Toxicology, 1993); Ralene Mitschler (Biology, 1994);
Raman Dayanidhi (Biochemistry, 1995); Rohan Thakur (Animal Science, outside chair, 1996);
Craig Whiteford (Biology, 1997); Kirk Pappan (Biochemistry, 1998); Eun He Kim (Horticulture,
outside chair, 1999); Li Zheng (Biochemistry, 2000); Chunbo Qin (Biochemistry, 2003); Peter
Moisan (Path/Micro, not completed); Weiqi Li (Biochemistry, 2005); Micheal Barnett
(Biochemistry, 2005); Venki Pegadraju (Biology, 2006); Robin Craig (Anatomy and Physiology,
current); Yanli Chen (Chemistry, completed M.S., 2008); Jun Hoon Lee (Agronomy, 2008); Robin
Craig (Anatomy and Physiology, 2007); Ping Ouyang (Human Nutrition, 2007); Kartikeya
Krothapalli (Biology, 2008); Ke “Kurt” Zhang (Statistics, 2008); William Miller (Animal Science
and Industry, outside chair, 2009); Sean Finnie (Grain Science and Industry, 2009); Akshay
Moharir (Biology, not completed); Sushanth Gudlar (Biochemistry, 2012); Huaien Dai
(Biochemistry, 2013); Lianqing Zheng (Statistics, 2013); Emily Archer Slone (Biology, 2013);
Ashley Sheppard (Psychology, outside chair, current); Lorne Jordan (Biochemistry, current); Tam
Tran Nguyen (Biochemistry, current); Sunil Bansal (Biochemistry, current); John Elson
(Mechanical Engineering, outside chair, current); Patrick Ryan Gibson (Purdue University, current);
Cesar Caballero (Animal Science and Industry, outside chair, current); Sruthi Narayanan
(Agronomy, current).
Masters committees: Craig Whiteford (Toxicology, 1994); Heidi Hinkel (Biology, 1996); Nancy
James (Biology, 1996); Dahao Ling (Biochemistry, 2000); Weiqi Li (Biochemistry, 2002); Yueyun
Hong (Biochemistry, 2005); Anisha Gupte (Biology, 2006); Jessica Morton (Biology, 2007); Lixia
Fan (Statistics, 2010); Tingting Song (Statistics, 2010); Dongwon Kim (Plant Pathology, 2011);
Jennifer Shelton (Biology, 2012); Daniel Stucky (Biology, 2013)
Biology committees (since 1993):
Seminar: chair, 1992-1994, member, 1994-2008
Tenure and promotion, 1993-1994; 2003-2004; 2007-current
Curriculum and undergraduate affairs, member, 1994-1999; chair, 1999-current, except fall 2001
Faculty search committee, chair, 2007-2008
Faculty search committee, 2009-2010
Faculty search committee for 3 positions, 2010-2011
University committees (non-Biology, since 1993):
Biochemistry Graduate Group member, 1986-current
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Biochemistry Graduate Group executive committee (elected), 1993-2002
Biochemistry tenure and promotion committee consultant, 1996
Arts and Sciences pre-vet advisor, 1997-1998
Pre-health evaluation committee, 1999-2000
Search committee for Arts and Sciences associate dean, 2003-2004
Biochemistry faculty search committee, 2004
Targeted Excellence Review Panel, 2007
Biochemistry faculty search committee, 2010-2011
Ad hoc group to provide input for development of the curriculum for a Professional Masters degree in
Biotechnology, 2010
Graduate Council and Graduate Student Affairs Committee, 2011-2012
2025 College of Agriculture/Kansas State Research and Extension/Facilities and Infrastructure
committee, 2012-2013
Currently funded awards
NSF MCB 0920663, Collaborative research: Metabolic profiling and functions of oxidized lipids in
plant stress responses (PI: Welti, Co-PI: Gadbury), Total award amount: $748,286, 8/1/09-7/31/14
NSF Research Opportunity Award MCB 1037957, Collaborative research: Metabolic profiling and
functions of oxidized lipids in plant stress responses (PI: Welti, Other personnel: Naidoo, Shah),
Total award amount: $14,999, 8/1/09-7/31/14
NIH 1R01 A1061691 01A2, Natural antibodies and tissue injury PI: Sherry Fleming, Co-PIs: Ruth
Welti & Stephen Chapes, Total award amount: $1,424,921, 3/1/07-2/28/14
NSF (Major Research Instrumentation program) DBI 1228622, MRI: Acquisition of a high-sensitivity
triple quadrupole mass spectrometer for the Kansas Lipidomics Research Center (PI: Welti, CoPIs: Durrett, Schrick; Senior Personnel: Shah, Wang) Total award amount: $443,484, 8/1/127/31/15.
USDA, 2013 Plant Lipids GRC/GRS (conference grant). (PI: Welti; Co-PI: Cahoon), Total award
amount: $ 15,000, 1/15/2013-1/14/2014.
Pending proposals
NSF-MCB, Collaborative Research: Lipidomic profiling, dynamics, and functions of head-group
acylation of membrane lipids in plant stress responses. (PI: Welti; Co-PIs: Gadbury, Naidoo,
Nikolau, and Wurtele) Total award amount: $991,602, 8/1/2013-7/31/2017.
Department of Defense: Reperfusion injury therapeutics targeting oxidized lipids. (PI: Fleming; CoPI: Welti), Total award amount: $187,445, 6/1/2014-5/31/2015.
Previously funded awards as PI
NSF MCB 1260252, 2013 Plant Lipids GRC/GRS (conference grant). (PI: Welti; Co-PI: Cahoon),
Total award amount: $ 10,000, 11/1/2012-10/31/2013.
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NIH, 2013 Plant Lipids GRC/GRS (conference grant). (PI: Welti; Co-PI: Cahoon), Total award
amount: $ 5,000, 12/1/2012-11/30/2013.
DOE, 2013 Plant Lipids GRC/GRS (conference grant). (PI: Welti; Co-PI: Cahoon), Total award
amount: $ 15,795, 12/15/20-12/14/2013.
KSU Targeted Excellence program, A Functional Genomics Consortium: Building research
productivity through education, interaction, and full utilization of the Functional Genomics
Laboratories at KSU (PI: Welti; Co-PIs: Kanost, Tomich, Prakash, Brown, Conrad, and Maatta)
$1,998,944, 7/1/06-12/31/11
K-INBRE, Institutional Core Facility Support: Sample preparation improvements at the Kansas
Lipidomics Research Center (KLRC) (PI: Welti), Total award amount: $40,000 (direct costs),
2009-2010
NSF (Major Research Instrumentation program) Acquisition of mass spectrometers for the Kansas
State University Functional Genomics Laboratories (PI: Welti, Co-PIs: Tomich, Blecha, Kanost,
Hulbert) Total award amount: $1,539,360, 9/1/05-8/31/08.
K-INBRE, Comprehensive analysis of human plasma lipids as potential markers of disease (PI: Welti),
Total award amount: $35,000 (direct costs), 5/01/06-4/30/07
K-INBRE, Institutional Core Facility Support: Kansas Lipidomics Research Center Analytical
Laboratory at Kansas State University (PI: Welti), Total award amount: $35,000 (direct costs),
5/01/06-4/30/07
K-INBRE (Bioinformatics), LipidomeDB, lipidomics data mining tools, and improvements in
lipidomics data processing (Welti, L.J. Wang, Milliken, and Brown), Total award amount:
$45,935 (direct costs), 5/01/06-4/30/07
Kansas NSF EPSCoR program, Acquisition of a mass spectrometer for lipidomics (PI: Welti, Co-PIs:
Schermerhorn, Shah, Valent and Wang) Total award amount: $319,999, 6/1/05-3/31/06.
K-INBRE (Bioinformatics), Kansas Lipidomics Research Center Analytical Laboratory: A Database
for Lipidomics (PI: Welti; Co-PI: L.J. Wang), Total award amount: $13,195, 07/22/04-6/30/05.
NSF EPSCoR/Kansas Technology Enterprise Corporation/KSU, Establishment of the Kansas
Lipidomics Research Center (PI: Welti (Original PI: Wang); Co-PIs: Shah, Rintoul, Sun,
Williams, Dobrowsky, LeVine), Total award amount: $1,238,840 (for KSU, $1,002,380), 4/01/033/31/06
Kansas Biomedical Research Infrastructure Network (KBRIN), Core facility support for the Kansas
Lipidomics Research Center Analytical Laboratory (PI: Welti), Total award amount: $25,575,
01/1/04-6/30/04
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Philippine Department of Science and Technology, The role of epidermal growth factor receptor
transmembrane domain primary signal transduction (Stipend and supply money for Norma Flores
during exchange visit to Welti lab), Total award amount: $28,325, 8/1/96-1/31/98
American Cancer Society, Inc., Characterization of membrane lipid domains (PI: Welti), Total award
amount: $200,000, 7/1/91-6/30/94
American Heart Association, Kansas Affiliate, Inc., Effect of copper on synthesis, secretion, and
uptake of pulmonary surfactant by rat type II aveolar cell (PI: Welti), Total award amount:
$44,000, 7/1/94-6/30/96
Fraternal Order of Eagles, Phospholipid acylation-deacylation cycles in heart mitochondria (PI: Welti),
Total Award Amount: $5,000, 10/1/93-9/30/95
American Heart Association, Kansas Affiliate, Inc., Characterization of heart mitochondrial inner
membrane lipid domains (PI: Welti), Total award amount: $44,000 (direct), 7/1/91-6/30/94
NSF (Career Advancement Award), Fluorescence microscopic visualization of lipid domains (PI:
Welti), Total award amount: $36,352 (direct), 8/1/92-7/30/94
NIH R01 GM34371, Characterization of membrane lipid domains (PI: Welti), 12/01/84-11/30/871987,
$197,134; Renewed, 12/01/87-11/30/90, amount not recorded.
Previously funded awards as Co-PI
NSF 2010 program MCB , Metabolomics: A functional genomics tool for deciphering functions of
Arabidopsis genes in the context of metabolic and regulatory networks (PI: Basil Nikolau, Co-PIs:
Oliver Fiehn, Seung Rhee, Lloyd Sumner, and Ruth Welti) Total award amount: $244,159
(subcontract to Welti), 3/1/2009-2/28/2012.
KUMC, Analysis of estradiol (CoPIs: Welti and Jeannotte), Total award amount: $12,500, 10/1/089/30-10
Cancer Therapeutics NIH COBRE Award at U. of Kansas (PI: B. Timmermann), Phosphatidylcholine
biosynthesis and anticancer agent miltefosine (PI: Zufferey, Co-PI: Welti), Total award amount (to
Welti): $11,500 (direct costs), 3/1/08-2/28/09
Winn Foundation, Identification of a biomarker for masked renal failure in hyperthyroid cats (PI:
Schermerhorn, Co-PIs: Gadbury, Jeannotte, Welti), Total award amount: $15,000, 1/1200912/31/10.
Kansas Infrastructure Network for Biomedical Research (K-INBRE), Lipidomics Bioinformatics:
Lipidome DB, Statistical applications, and data processing (Brown, Welti), Total Award Amount:
$26,000, 07/1/07-4/30/08
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NSF, Role of Arabidopsis SFD1 in systemic acquired resistance (PI: Shah; Co-PI: Welti), Total Award
Amount: $375,000, 9/01/06- 8/31/09
USDA-NRI, Arabidopsis-Green peach aphid interaction (PI: Shah; Co-PIs: Reese and Welti) Total
Award Amount: $378,679, 8/1/04-7/31/07
NIH, Novel proapoptotic BH3-only proteins in cancer apoptosis (PI: Hu, Co-PI: Welti) Total Award
Amount: (KSU subcontract, $72,672), 4/1/05-3/31/10
NSF 2010 Project, Metabolomics: A functional genomics tool for deciphering functions of Arabidopsis
genes in the context of metabolic and regulatory networks (PI: Nikolau, Co-PIs: Fiehn, Rhee,
Sumner, and Welti), Total Award Amount: $1,000,000 (KSU award: $84,402), 9/1/05-8/31/07.
Kansas Infrastructure Network for Biomedical Research (K-INBRE), Kansas Lipidomics Research
Center Analytical Laboratory: LipidomeDB and Associated Data Mining Tools (Brown, Welti,
and L.J. Wang), Total Award Amount: $22,820, 07/1/05-6/30/06
NSF, Metabolomic profiling of lipids and their compositional dynamics in plant stress response (PI:
Wang; Co-PIs: Shah, Welti and Williams) Total Award Amount: $810,976 (Welti portion,
$338,013), 9/1/04-8/31/08
NSF, Metabolomic profiling of membrane lipids and their compositional dynamics in plant stress
responses (PI: Wang; Co-PIs: Shah, Welti and Williams), Total Award Amount: $488,689,
9/15/01-8/31/05
NSF (MRI program), Acquisition of five controlled environmental chambers for plant research (P.I.:
Shah; Co-P.I.s/Co-Investigators: Roe, Wang, Guikema, Reese, Muthukrishnan, Zhou and Welti),
Total Award Amount: $126,419 plus KSU $54,179 (match), 8/15/00-7/31/02
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PUBLICATIONS
Research Articles
1. Brenckle (Welti), Ruth, and Kornfeld, Rosalind. 1980. Structure of the oligosaccharide of mouse
immunoglobulin M secreted by the MOPC 104 E plasmacytoma. Arch. Biochem. Biophys. 201,
160-173.
2. Welti, Ruth, Rintoul, David A., Goodsaid-Zalduondo, Federico, Felder, Stephen, and Silbert,
David, F. 1981. Gel phase phospholipid in the plasma membrane of sterol-depleted mouse LM
cells: Analysis by fluorescence polarization and X-Ray diffraction. J. Biol. Chem. 256,
7528-7535.
3. Welti, Ruth, and Silbert, David F. 1982. Partition of parinaroyl phospholipid probes between solid
and fluid phosphatidylcholine phases. Biochemistry 21, 5685-5689.
4. Welti, Ruth. 1982. Partition of parinaroyl phospholipids in mixed head group systems.
Biochemistry 21, 5690-5693.
5. Welti, Ruth, and Helmkamp, George, M., Jr. 1984. Acyl chain specificity of phosphatidylcholine
transfer protein from bovine liver. J. Biol. Chem. 259, 6937-6941.
6. Welti, Ruth, Mullikin, Lee, J., Yoshimura, Tetsuro, and Helmkamp, George, M., Jr. 1984.
Partition of amphiphilic molecules into phospholipid vesicles and human erythrocyte ghosts:
Measurements by ultraviolet difference spectroscopy. Biochemistry 23, 6086-6091.
7. Yoshimura, Tetsuro, Welti, Ruth, and Helmkamp, George M., Jr. 1988. General kinetic model for
protein-mediated phospholipid transfer between membranes. Arch. Biochem. Biophys. 266,
299-312.
8. Rintoul, David A., and Welti, Ruth. 1989. Thermotropic behavior of mixtures of
glycosphingolipids and phosphatidylcholine: Effect of monovalent cations on sulfatide and
galactosylceramide. Biochemistry 28, 26-31.
9. Roth, Mary R., Smardo, Fred L., Jr., and Welti, Ruth. 1989. Analysis of dimeric species derived
from the reaction of phosphatidylethanolamine species with dimethylsuberimidate. Chem. Phys.
Lipids. 51, 39-46.
10. Roth, Mary R., Avery, Robert B., and Welti, Ruth. 1989. Cross-linking of
phosphatidylethanolamine neighbors with dimethylsuberimidate is sensitive to the lipid phase.
Biochim. Biophys. Acta. 986, 217-224.
11. Martin, Lee R., Avery, Robert B., and Welti, Ruth. 1990. Partition of parinaroyl
phosphatidylethanolamines and parinaroyl phosphatidylglycerols in immiscible phospholipid
mixtures. Biochim. Biophys. Acta. 1023, 383-388.
12. Song, Wenxia, Vacca, Mark F., Welti, Ruth, and Rintoul, David A. 1991. Effects of gangliosides
GM3 and De-N-acetyl GM3 on epidermal growth factor receptor kinase activity and cell growth. J.
Biol. Chem. 266, 10174-10181.
14
13. Roth, Mary R. and Welti, Ruth. 1991. Lipid arrangement in fluid model membranes: analysis by
cross-linking of phosphatidylethanolamines. Biochim. Biophys. Acta.1063, 2042-2046.
14. Harrison, Melissa M., Roth, Mary R., Hooker, Ana A., Rintoul, David A. and Welti, Ruth. 1993.
Phase behavior and arrangement of molecular species in mixtures of a mixed chain and a
symmetric phosphatidylethanolamine in the gel and fluid phases. Biochim. Biophys. Acta 1149,
292-298.
15. Song, Wenxia, Haffner-Strauss, Sabrina, Welti, Ruth, and Rintoul, David A. 1993. Synthesis and
characterization of N-parinaroyl analogs of ganglioside GM3. Biochemistry 32, 8602-8607.
16. Mitschler, Ralene R., Welti, Ruth, and Upton, Steve J. 1994. A comparative study of lipid
compositions of Cryptosporidium parvum (Apicomplexa) and Madin-Darby bovine kidney cells.
J. Eukaryotic Microbiology 41, 8-12.
17. Roth, Mary R. and Welti, Ruth. 1994. Arrangement of phosphatidylethanolamine molecular
species in Escherichia coli membranes and reconstituted lipids as determined by
dimethylsuberimidate cross-linking of nearest neighbor lipids. Biochim. Biophys. Acta. 1190, 9198.
18. Abdel-Mageed, Asim B., Welti, Ruth, Oehme, Frederick W., and Pickrell, John A. 1994. Perinatal
effects of hypocuprosis on synthesis and composition of neonatal lung collagen, elastin and
surfactant. Amer. J. Physiol. 267, L679-L685.
19. Bartlett, Danny, Glaser, Michael, and Welti, Ruth. 1997. Penetration depth and lipid phase
preference of acyl-labeled dansyl phosphatidylcholines in phosphatidylcholine vesicles. Biochim.
Biophys. Acta 1328, 48-54.
20. Wang, Cunxi, Zien, Christopher A., Afitlhile, Meshack, Welti, Ruth, Hildebrand, David F., and
Wang, Xuemin. 2000. Involvement of phospholipase D in wound-induced accumulation of
jasmonic acid in Arabidopsis. Plant Cell 12, 2237-2246.
21. Zien, Christopher A., Wang, Cunxi, Wang, Xuemin, and Welti, Ruth. 2001. In-vivo substrates
and the contribution of the common phospholipase D, PLDα, to wound-induced metabolism of
lipids in Arabidopsis. Biochim. Biophys. Acta [Molecular and Cell Biology of Lipids] 1530, 236248.
22. Welti, Ruth, Li, Weiqi, Li, Maoyin, Sang, Yongming, Biesiada, Homigol, Zhou, Han-E,
Rajashekar, C.B., Williams, Todd D., and Wang, Xuemin. 2002. Profiling membrane lipids in
plant stress responses: role of phospholipase D-α in freezing-induced lipid changes in Arabidopsis.
J. Biol. Chem. 277, 31994-32002.
23. Welti, Ruth, Wang, Xuemin, and Williams, Todd D. 2003. Electrospray ionization tandem mass
spectrometry scan modes for plant chloroplast lipids. Anal. Biochem. 314, 149-152.
24. Fauconnier, Marie-Laure, Welti, Ruth, Blée, Elisabeth, and Marlier, Michel. 2003. Lipid and
oxylipin profiles during aging and sprout development in potato tubers (Solanum tuberosum L.).
Biochim. Biophys. Acta 1633, 118-126.
15
25. Fauconnier, Marie-Laure, Williams, Todd D, Marlier, Michel, and Welti, Ruth. 2003. Potato tuber
phospholipids contain colneleic acid in the 2-position. FEBS Letters 538, 155-158.
26. Nandi, Ashis, Krothapalli, Kartik, Buseman, Christen M., Li, Maoyin, Welti, Ruth, Enyedi,
Alexander, and Shah, Jyoti. 2003. The Arabidopsis thaliana sfd mutants affect plastidic lipid
composition and suppress dwarfing, cell death and the enhanced disease resistance phenotypes
resulting from the deficiency of a fatty acid desaturase. Plant Cell 15, 2383-2398.
27. Zhang, Wenhua, Wang, Cunxi, Qin, Chunbo, Wood, Tara, Olafsdottir, Gudrun, Welti, Ruth, and
Wang, Xuemin. 2003. The oleate-stimulated phospholipase D, PLDδ, and phosphatidic acid
decrease H2O2-induced cell death in Arabidopsis. Plant Cell 15, 2285-2295.
28. Nandi, Ashis, Welti, Ruth, and Shah, Jyoti. 2004. The Arabidopsis thaliana dihydroxyacetone
phosphate reductase gene SUPPRESSOR OF FATTY ACID DESATURASE DEFICIENCY1 is
required for glycerolipid metabolism and for the activation of systemic acquired resistance. Plant
Cell 16, 465-477.
29. Li, Weiqi, Li, Maoyin, Zhang, Wenhua, Welti, Ruth, and Wang, Xuemin. 2004. The plasma
membrane-bound phospholipase Dδ enhances freezing tolerance in Arabidopsis thaliana. Nature
Biotech. 22, 427-433.
30. Abbadi, Amine, Domergue, Fréderic, Bauer, Jörg, Napier, Johnathan A., Welti, Ruth, Zahringer,
Ulrich, Cirpus, Petra, and Heinz, Ernst. 2004. Biosynthesis of very long-chain polyunsaturated
fatty acids in transgenic oilseeds: Constraints on their accumulation. Plant Cell 16, 2734-2748.
31. Sabah, Judith, McConkey, Eric, Welti, Ruth, Albin, K., and Takemoto, Larry. 2005. Role of
albumin as a fatty acid carrier for biosynthesis of lens lipids. Experimental Eye Research 80, 3136.
32. Wanjie, Sylvia W., Welti, Ruth, Moreau, Robert A., and Chapman, Kent D. 2005. Identification and
quantification of glycerolipids in cotton fibers: Reconciliation with metabolic pathway predictions
from DNA databases, Lipids 40, 773-785.
33. Young, Janice E., Zhao, Xin, Carey, Edward E., Welti, Ruth, Yang, Shie-Shien, and Wang, Weiqun.
2005. Phytochemical phenolics in organically-grown vegetables journal of agricultural and food
chemistry. Mol. Nutr. Food Res. 49, 1136-1142.
34. Li, Maoyin, Qin, Chunbo, Welti, Ruth, and Wang, Xuemin. 2006. Double knockouts of
phospholipase Dζ1 and ζ2 in Arabidopsis affect root elongation under phosphate limitation, but do
not affect root hair patterning. Plant Physiol. 140, 761-770.
35. Wang, Xuemin, Devaiah, Shivakumar Pattada, Zhang, Wenhua, and Welti, Ruth. 2006. Signaling
functions of phosphatidic acid. Prog. Lipid Res. 45, 250-278.
36. Devaiah, Shivakumar P., Roth, Mary R., Baughman, Ethan, Li, Maoyin, Tamura, Pamela,
Jeannotte, Richard, Welti, Ruth, and Wang, Xuemin. 2006. Quantitative profiling of polar
glycerolipid species and the role of phospholipase Dα1 in defining the lipid species in Arabidopsis
tissues. Phytochemistry 67, 1907-1924.
16
37. Buseman, Christen M., Tamura, Pamela, Sparks, Alexis A., Baughman, Ethan J., Maatta, Sara,
Zhao, Jian, Roth, Mary R., Esch, Steven Wynn, Shah, Jyoti, Williams, Todd D., and Welti, Ruth
2006. Wounding stimulates the accumulation of glycerolipids containing oxophytodienoic acid and
dinor-oxophytodienoic acid in Arabidopsis leaves. Plant Physiol. 142, 28-39.
38. Li, Maoyin, Welti, Ruth, and Wang, Xuemin. 2006. Quantitative profiling of Arabidopsis polar
glycerolipids in response to phosphorus starvation: Roles of PLDζ1 and PLDζ2 in
phosphatidylcholine hydrolysis and digalactosyldiacylglycerol accumulation in phosphorus-starved
plants. Plant Physiol. 142, 750-761.
39. Esch, Steven Wynn, Tamura, Pamela, Sparks, Alexis A., Roth, Mary R., Devaiah, S. P., Heinz,
Ernst, Wang, Xuemin, Williams, Todd D., and Welti, Ruth. 2007. Rapid characterization of fatty
acyl composition of complex lipids by collision-induced dissociation time-of-flight mass
spectrometry. J. Lipid. Res. 48, 235-241.
40. Fitzgerald, Michael L., Xavier, Ramnik, Haley, Kathleen J., Welti, Ruth, Goss, Julie L., Brown,
Cari E., Zhuang, Debbie, Bell, Susan A., Lu, Naifang, Mckee, Mary, Seed, Brian, and Freeman,
Mason W. 2007. ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary
surfactant and depletion of lung phosphatidylglycerol. J. Lipid Res. 48, 621-632.
41. Fritz, Markus, Lokstein, Heiko, Hackenberg, Dieter, Welti, Ruth, Roth, Mary, Zähringer, Ulrich,
Fulda, Martin, Hellmeyer, Wiebke, Ott, Claudia, Wolter, Frank P., and Heinz, Ernst. 2007.
Chanelling of eukaryotic diacylglycerol into the biosynthesis of plastidial phosphatidylglycerol. J.
Biol. Chem. 282, 4613-4625.
42. Hsu, Fong-Fu, Turk, John, Williams, Todd D., and Welti, Ruth. 2007. Electrospray ionization
multiple stage quadrupole ion-trap and tandem quadrupole mass spectrometric studies on
phosphatidylglycerol from Arabidopsis leaves. J. Am. Soc. Mass Spec. 18, 783-790.
43. Bartz, Rene, Li, Wen-Hong, Venables, Barney, Zehmer, John, Welti, Ruth, Anderson, Richard,
Liu, Ping-sheng, and Chapman, Kent D. 2007. Lipidomics reveals adiposomes store ether lipids
and mediate phospholipid traffic. J. Lipid Res. 48, 837-847.
44. Yang, Wenyu, Devaiah, Shivakumar, Pan, Xiangqing, Isaac, Giorgis, Welti, Ruth, and Wang,
Xuemin. 2007. AtPLAI is an LRR-containing acyl hydrolase involved in basal jasmonic acid
production and Arabidopsis resistance to Botrytis cinerea. J. Biol. Chem. 282, 18116-18128.
45. Devaiah, Shivakumar P., Pan, Xiangqing, Hong, Yueyun, Roth, Mary R., Welti, Ruth, and Wang,
Xuemin. 2007. Enhancing seed quality and viability by suppressing phospholipase D in
Arabidopsis. Plant J. 50, 950-957.
46. Welti, Ruth, Mui, Ernie, Sparks, Alexis, Wernimont, Sarah, Isaac, Giorgis, Kirisits, Michael, Roth,
Mary, Roberts, Craig W., Botté, Cyrille, Maréchal, Eric, and McLeod, Rima. 2007. Lipidomic
analysis of T. gondii reveals unusual polar lipids. Biochemistry 46, 13882-13890.
47. Li, Weiqi, Wang, Ruiping, Li, Maoyin, Li, Lixia, Wang, Chuanming, Welti, Ruth, and Wang,
Xuemin. 2008. Differential degradation of extraplastidic and plastidic lipids during freezing and
post-freezing recovery in Arabidopsis thaliana. J. Biol. Chem. 283, 461-468.
17
48. Chaturvedi, Ratnesh, Krothapalli, Kartikeya, Makandar, Ragiba, Nandi, Ashis, Sparks, Alexis,
Roth, Mary, Welti, Ruth, and Shah, Jyoti. 2008. Plastid ω3-fatty acid desaturase-dependent
accumulation of a systemic acquired resistance inducing activity in petiole exudates of Arabidopsis
thaliana is independent of jasmonic acid. Plant J. 54, 106-117.
49. Maeda, Hiroshi, Sage, Tammy L., Isaac, Giorgis, Welti, Ruth, and DellaPenna, Dean. 2008.
Tocopherols modulate extra-plastidic polyunsaturated fatty acid metabolism in Arabidopsis at low
temperature. Plant Cell 20, 452-470.
50. Botté, Cyrille, Saïdani, Nadia, Mondragon, Ricardo, Mondragon, M., Isaac, Giorgis, Mui, Ernest,
McLeod, Rima, Dubremetz, Jean-François, Vial, Henri, Welti, Ruth, Cesbron-Delauw, MarieFrance, Mercier, Corinne, and Maréchal, Eric. 2008. Subcellular localization and dynamics of a
digalactolipid-like lipid along the life cycle of the apicomplexan parasite Toxoplasma gondii. J.
Lipid Res. 49, 746-762.
51. Hong, Yueyun, Pan, Xiangqing, Welti, Ruth, and Wang, Xuemin. 2008. Alterations of
phospholipase Dα3 change Arabidopsis response to salinity and water deficits. Plant Cell 20, 803816.
52. Pan, Xiangqing, Welti, Ruth, and Wang, Xuemin. 2008. Simultaneous quantification of
phytohormones and related metabolites in crude plant extracts by liquid chromatographyelectrospray tandem mass spectrometry. Phytochemistry 69, 1773-1781.
53. Moreau, Robert A., Doehlert, Douglas C., Welti, Ruth, Isaac, Giorgis, Roth, Mary, Tamura,
Pamela, and Nuñez, Alberto. 2008. The identification of mono-, di-, tri-, and tetragalactosyldiacylglycerols and their natural estolides in oat kernels. Lipids. 43, 533-548.
54. Hong, Yueyun, Pan, Xiangqing, Welti, Ruth, and Wang, Xuemin. 2008. The effect of
phospholipase Dα3 on Arabidopsis response to hyperosmotic stress and glucose. Plant Signal
Behav. 3, 1099-1100.
55. Zuo, Ying, Zhuang, Debbie Z., Han, Rong, Isaac, Giorgis, Manning, Jennifer J., McKee, Mary,
Welti, Ruth, Brissette, Janice L., Fitzgerald, Michael L., and Freeman, Mason W. 2009. ABCA12
maintains the epidermal lipid permeability barrier via formation of ceramide linoleic esters J. Biol.
Chem. 284, 3345–3353.
56. Hong, Yueyun, Devaiah, Shivakumar P., Bahn, SungChul, Thamasandra, Bharath N., Li, Maoyin,
Welti, Ruth, and Wang, Xuemin. 2009. Phospholipase Dε and phosphatidic acid enhance
Arabidopsis growth. Plant J. 58, 376-387.
57. Jao, Cindy Y., Roth, Mary, Welti, Ruth, and Salic, Adrian. 2009. Metabolic labeling and direct
imaging of choline phospholipids in vivo. Proc Natl Acad Sci U S A. 106, 15332-15337.
58. Su, Kemin, Bremer, Dale J., Jeannotte, Richard, Welti, Ruth, and Yang, Celeste. 2009. Membrane
lipid composition and heat tolerance in cool-season turfgrasses including a hybrid bluegrass. Am.
Soc. Hort. Sci. 134, 511-520.
18
59. Zhang, Yanyan, Zhu, Huiying, Zhang, Qun, Li, Maoyin, Yan, Min, Wang, Rong, Wang, Liling,
Welti, Ruth, Zhang, Wenhua, and Wang, Xuemin. 2009. Phospholipase D 1 and phosphatidic acid
regulate NADPH oxidase activity and production of reactive oxygen species in ABA-mediated
stomatal closure in Arabidopsis. Plant Cell 21, 2357-2377.
60. Sparkes, Byron, Slone, Emily E, Roth, Mary, Welti, Ruth, and Fleming, Sherry D. 2010.
Ischemia/reperfusion-induced intestinal lipid alterations occur prior to antibody-induced PGE2
production. Biochim. Biophys. Acta (Molecular and Cell Biology of Lipids) 1801, 517-525.
61. Bais, Preeti, Moon, Stephanie M., He, Kun, Leitao, Ricardo, Dreher, Kate, Walk, Tom, Sucaet,
Yves, Barkan, Lenore, Wohlgemuth, Gert, Roth, Mary R., Wurtele, Eve S., Dixon, Philip, Fiehn,
Oliver, Lange, B. Markus, Shulaev, Vladimir, Sumner, Lloyd W., Welti, Ruth, Nikolau, Basil J.,
Rhee, Seung Y., and Dickerson, Julie A. 2010. PlantMetabolomics.org: a web portal for plant
metabolomics experiments. Plant. Physiol. 152, 1807-1816.
62. Ouyang, Ping, Jiang, Yu, Doan, Hieu M., Xie, Linglin, Vasquez, David, Welti, Ruth, Su, Xiaoyu,
Lu, Nanyan, Herndon, Betty, Yang, Shie-Shien, Jeannotte, Richard, and Wang, Weiqin. 2010.
Weight loss via exercise with controlled dietary intake may affect phospholipid profile for cancer
prevention in murine skin tissues. Cancer Prev. Res. (Phila Pa). 3, 466-477.
63. Xiao, S., Gao, W., Chen, Q.-F., Chan, S-W., Zheng, S.-X., Ma, J., Wang, M., Welti, R., and Chye,
M.-L. 2010. Overexpression of Arabidopsis acyl-CoA binding protein ACBP3 promotes
starvation-induced and age-dependent leaf senescence. Plant Cell 22, 1463-1482.
64. Singh, Ashutosh, Prasad, Tulika, Kapoor, Khyati, Mandal, Ajeet, Roth, Mary, Welti, Ruth, and
Prasad, Rajendra 2010. Phospholipidome of Candida: Each species of Candida has distinctive
phospholipid molecular species. OMICS: A Journal of Integrative Biology 14, 665-677.
65. Doehlert, Douglas C., Moreau, Robert A., Welti, Ruth, Roth, Mary, and McMullen, Michael S.
2010. Polar lipids from oat kernels. Cereal Chemistry. 87, 467-474.
66. Pan, Xiangqing, Welti, Ruth, and Wang, Xuemin. 2010. Quantitative analysis of major plant
hormones in crude plant extracts by high-performance liquid chromatography-mass spectrometry.
Nat. Protoc. 5, 986-992.
67. Peters, Carlotta, Li, Maoyin, Narasimhan, R., Roth, Mary, Welti, Ruth, and Wang, Xuemin. 2010.
Nonspecific phospholipase C NPC4 promotes responses to abscisic acid and tolerance to
hyperosmotic stress in Arabidopsis. Plant Cell 22, 2642-2659.
68. Kilaru, Aruna, Isaac, Giorgis, Tamura, Pam, Baxter, David, Duncan, Scott R., Venables, Barney J.,
Welti, Ruth, Koulen, Peter, and Chapman, Kent D. 2010. Targeted lipidomics of endocannabinoid
pathway metabolites in murine brain and heart. Lipids. 45, 863-875
69. Kilaru, Aruna*, Tamura, Pamela* (* = equal contribution), Puja, Garg, Isaac, Giorgis, Baxter,
David, Duncan, R. Scott, Welti, Ruth, Koulen, Peter, Chapman, Kent D., and Venables, Barney J.
2010. Changes in N-acylethanolamine pathway related metabolites in a rat model of cerebral
ischemia/reperfusion. J. Glycom. Lipidom. 1, 101. doi:10.4172/2153-0637.1000101
19
70. Deng, Youping, Meyer, Sharon A., Guan, Xin, Escalon, Barbara Lynn, Ai, Junmei, Wilbanks,
Mitchell S., Welti, Ruth, Garcia-Reyero, Natàlia, and Perkins, Edward J. 2011. Analysis of
common and specific mechanisms of liver function affected by nitrotoluene compounds. PLoS
ONE. 6, e14662.
71. Clauss, Kathleen, von Roepenack-Lahaye, Edda, Boettcher, Christoph, Roth, Mary R., Welti, Ruth,
Erban, Alexander, Kopka, Joachim, Scheel, Dierk, Milkowski, Carsten, and Strack, Dieter. 2011.
Overexpression of sinapine esterase BnSCE3 in Brassica napus seeds triggers global changes in
seed metabolism. Plant Physiol. 155, 1127-1145.
72. Li, Maoyin, Bahn, Sung Chul, Guo, Liang, Musgrave, William, Berg, Howard, Welti, Ruth, and
Wang, Xuemin. 2011. Patatin-related phospholipase pPLAIIIβ-induced changes in lipid
metabolism alter cellulose content and cell elongation in Arabidopsis. Plant Cell. 23, 1107-1123.
73. Lee, Junghoon, Welti, Ruth, Schapaugh, William T., and Trick, Harold N. 2011. Phospholipid and
triacylglycerol profiles modified by PLD suppression in soybean seed. Plant Biotechnol. J. 9, 359372.
74. Zhou, Zhenguo, Marepally, Shantan Reddy, Nune, Daya Sagar, Pallakollu, Prashanth, Ragan, Gail,
Roth, Mary R., Wang, Liangjiang, Lushington, Gerald H., Visvanathan, Mahesh, and Welti, Ruth.
2011. LipidomeDB Data Calculation Environment: Online processing of direct-infusion mass
spectral data for lipid profiles. Lipids. 46, 879-884.
75. Lattif, Ali Abdul, Mukherjee, Pranab K., Chandra, Jyotsna, Roth, Mary R., Welti, Ruth, Rouabhia,
Mahmoud, and Ghannoum, Mahmoud A. 2011. Lipidomics of Candida albicans biofilms reveals
phase-dependent production of phospholipid molecular classes and role for lipid rafts in biofilm
formation. Microbiology 157, 3232-3242. PMID: 21903752
76. Zhao, Jian, Wang, Cunxi, Welti, Ruth, Bedair, Mohamed, Sumner, Lloyd, Baxter, Ian, and Wang,
Xuemin. 2011. Suppression of phospholipase Dγs confers increased aluminum resistance in
Arabidopsis thaliana. PLoS One. 6(12), e28086. doi:10.1371/journal.pone.0028086
77. Lee, Junghoon, Welti, Ruth, Roth, Mary, Schapaugh, William T., Li, Jiarui, and Trick, Harold.
2012. Enhanced seed viability and lipid compositional changes during natural aging by suppressing
phospholipase Dα in soybean seed. Plant Biotechnol. J. 10, 164-173. DOI: 10.1111/j.14677652.2011.00650.x
78. Schrick, Kathrin, Shiva, Sunitha, Arpin, James, Delimont, Nicole, Isaac, Giorgis, Tamura, Pam,
and Welti, Ruth. 2012. Steryl glucoside and acyl steryl glucoside analysis of Arabidopsis seeds by
electrospray ionization tandem mass spectrometry. Lipids 47, 185-193.
79. Vu, Hieu Sy, Tamura, Pamela, Galeva, Nadezhda A., Chaturvedi, Ratnesh, Williams, Todd D.,
Wang, Xuemin, Shah, Jyoti, and Welti, Ruth. 2012. Direct infusion mass spectrometry of oxylipincontaining Arabidopsis thaliana membrane lipids reveals varied patterns in different stress
responses. Plant Physiol. 158, 324-339.
80. Yang, Wenyu, Zheng, Yong, Bahn, SungChul, Pan, Xiangqing, Li, Maoyin, Vu, Hieu Sy, Roth,
Mary R., Scheu, Brad, Welti, Ruth, and Wang, Xuemin. 2012. Patatin-related phospholipase A
20
pPLAIIα modulates oxylipin formation and water loss in Arabidopsis thaliana. Mol. Plant. 5, 452460.
81. Quanbeck, Stephanie M., Brachova, Libuse, A., Campbell, Alexis, Guan, Xin, Perera, Ann, He,
Kun, Rhee, Seung, Bais, Preetis, Dickerson, Julie A., Dixon, Philip, Wohlgemuth, Gert, Fiehn,
Oliver, Barkan, Lenore, Lange, Iris, Lange, B. Markus, Lee, Insuk, Cortes, Diego, Salazar,
Caroline, Shuman, Joel, Shulaev, Vladimir, Huhman, David V., Sumner, Lloyd W., Roth, Mary R.,
Welti, Ruth, Ilarslan, Hilal, Wurtele, Eve S., and Nikolau, Basil J. 2012. Metabolomics as a
hypothesis-generating 1 functional genomics tool for the annotation of Arabidopsis thaliana genes
of “unknown function”. Front. Plant Sci. 3:15. doi: 10.3389/fpls.2012.00015
82. Guo, Liang, Mishra, Girish, Markham, Jonathan, Li, Maoyin, Tawfall, Amanda, Welti, Ruth, and
Wang, Xuemin. 2012. Connections between sphingosine kinase and phospholipase D in the
abscisic acid signaling in Arabidopsis. J. Biol. Chem. 287, 8286-8296.
83. Lorenc-Kukula, Katarzyna, Chaturvedi, Ratnesh, Roth, Mary, Welti, Ruth, and Shah, Jyoti. 2012.
Biochemical and molecular-genetic characterization of SFD1’s involvement in lipid metabolism
and defense signaling. Front. Plant Sci. 3, 26. doi: 10.3389/fpls.2012.00026
84. Zhu, Lieceng, Liu, Xuming, Wang, Haiyan, Khajuria, Chitvan, Reese, John C., Whitworth, R. Jeff,
Welti, Ruth, and Chen, Ming-Shun. Rapid mobilization of membrane lipids in wheat leaf-sheaths
during incompatible interactions with Hessian fly. MPMI 25, 920-930.
85. Maatta, Sara, Scheu, Brad, Roth, Mary R., Tamura, Pamela, Li, Maoyin, Williams, Todd D.,
Wang, Xuemin, and Welti, Ruth. 2012. Levels of Arabidopsis thaliana leaf phosphatidic acids,
phosphatidylserines, and most trienoate-containing polar lipid molecular species increase during
the dark period of the diurnal cycle. Front. Plant Sci. 3:49. doi: 10.3389/fpls.2012.00049.
86. Kilaru, Aruna*, Tamura, Pamela* (* = equal contribution), Isaac, Giorgis, Welti, Ruth, Venables,
Barney J., and Chapman, Kent D. 2012. Lipidomic analysis of N-acylphosphatidylethanolamine
molecular species in Arabidopsis suggests feedback regulation by N-acylethanolamines. Planta
236, 809-824.
87. Slone, Emily A., Pope, Michael R., Roth, Mary, Welti, Ruth, Fleming, Sherry D. 2012. TLR9 is
dispensable for intestinal ischemia/reperfusion-induced tissue damage. Am. J. Clin. Exp. Immunol.
1, 124-135.
88. Zhou, X., Mao, J., Ai, J., Deng, Y., Roth, M.R., Pound, C.R., Henegar, J., Welti, R., and Bigler,
S.A. 2012. Identification of plasma lipid biomarkers for prostate cancer by lipidomics and
bioinformatics. PLoS One. 7(11):e48889. doi: 10.1371/journal.pone.0048889
89. Ju, Songwen, Mu, Jingyao, Dokland, Terje, Zhuang, Xiaoying, Wang, Qilong, Jiang, Hong, Xiang,
Xiaoyu, Deng, Zhong-Bin, Wang, Baomei, Zhang, Lifeng, Roth, Mary, Welti, Ruth, Mobley,
James, Jun, Yan, Miller, Donald, and Zhang, Huang-Ge. 2013. Grape exosome-like nanoparticles
induce intestinal stem cells and protect mice from DSS-induced colitis. Molecular Therapy 21,
1345-1357.
21
90. Kim, Dongwon, Jeannotte, Richard, Welti, Ruth, and Bockus, William W. 2013. Lipid profiles in
wheat cultivars resistant and susceptible to tan spot and the effect of disease on the profiles.
Phytopathology 103, 74-80.
91. Li, Maoyin, Bahn, S.C., Fan, C., Li, J., Phan, T., Ortiz, M., Roth, Mary R., Welti, Ruth, and Wang,
Xuemin. 2013. Patatin-related phospholipase pPLAIIIδ increases seed oil content with long-chain
fatty acids in Arabidopsis. Plant Physiol. 162, 39-51.
92. McHaney, Anastasia M., Welti, Ruth, Roth, Mary R., Dinnetz, Joyce M., Furney, S.R.,
Pendergraft, Jeffrey S., Epp, T.S., and Minton, J. Ernest. 2013. Omega-3 fatty acid
supplementation affects selected phospholipids in peripheral white blood cells and in plasma of
full-sized and miniature mares. J. Equine Vet. Sci. 33, 779-786.
93. Narasimhan, Rama, Wang, Geliang, Roth, Mary, Welti, Ruth, and Wang, Xuemin. 2013.
Differential changes in galactolipid and phospholipid species in soybean leaves and roots under
nitrogen deficiency and after nodulation. Phytochemistry 96, 81-91.
94. Zhao, Jian, Devaiah, Shiva P., Wang, Cunxi, Li, Maoyin, Welti, Ruth, and Wang, Xuemin. 2013.
Arabidopsis phospholipase Dβ1 modulates defense responses to bacterial and fungal pathogens.
New Phytol. 199, 228-240.
95. Zheng, Lianqing, Gadbury, Gary, Shah, Jyoti, and Welti, Ruth. 2013. Exploration of reactantproduct lipid pairs in mutant-wild type lipidomics experiments. The 2012 Proceedings of the
Conference on Applied Statistics in Agriculture.
96. Haller, J. F., Cavallaro, P., Hernandez, N. J., Dolat, L., Soscia, S. J., Welti, R., Sun, Y., Grabowski,
G. A., Milstone, L. M., Fitzgerald, M. L., and Freeman, M. W. 2013. Endogenous βglucocerebrosidase activity in Abca12-/-epidermis elevates ceramide levels after topical lipid
application but does not restore barrier function. J. Lipid Res. In press.
97. Li, Maoyin, Baughman, Ethan, Roth, Mary R., Han, Xianlin, Welti, Ruth, and Wang, Xuemin.
2013. Quantitative profiling and pattern analysis of triacylglycerol species in Arabidopsis seeds by
electrospray ionization mass spectrometry. Plant J. In press.
98. Vu, Hieu Sy, Roth, Mary R., Tamura, Pamela, Samarakoon, Thilani, Shiva, Sunitha, Honey,
Samuel, Lowe, Kaleb, Schmelz, Eric A., Williams, Todd D., and Welti, Ruth. 2013. Head-group
acylation of monogalactosyldiacylglycerol is a common stress response, and the acyl-galactose
acyl composition varies with the plant species and applied stress. Physiol. Plant. In press.
22
Review Articles, Methods, and Book Chapters
1. Welti, Ruth and Glaser, Michael. 1994. Lipid domains in model and biological membranes.
Chem. Phys. Lipids. 73,121-137.
2. Wang, Xuemin, Wang, Cunxi, Sang, Yongming. Qin, Chunbo, and Welti, Ruth. 2002. Networking
of phospholipases in plant signal transduction. Physiologica Plantarum.115, 331-335.
3. Qin, Chunbo, Li, Weiqi, Hong, Yueyun, Zhang, Wenhua, Wood, Tara, Li, Maoyin, Welti, Ruth,
and Wang, Xuemin. 2003. Two novel types of Arabidopsis phospholipase D: Oleate-stimulated
PLDδ and Ca2+-independent PLDς1. In “Advanced Research on Plant Lipids”, ed. Murata, N.,
Yamada, M., Nishida, I., Okuyama, H., Sekiya, J., and Hajime, W. Kluwer Academic Publishers,
Dordrecht/Boston/London. pp. 259-262.
4. Welti, Ruth, and Wang, Xuemin. 2003. Lipidomics. Inform 14, 607-608.
5. Shah, Jyoti, Nandi, Ashis, Buseman, Christen M., Li, Maoyin, Krothapalli, Kartik, Pegadaraju,
Venki, Buffington, Rachel, Morton, Jessica, Omoluabi, O., Baughman, Ethan, and Welti, Ruth.
2004. Salicylic acid signaling in plant defense: the lipid connection, In “Biology of Molecular
Plant-Microbe Interaction”, B. Lugtenberg, I. Tikhonovich and N. Provorov, eds. Vol. 4.
American Phytopathological Society Press.
6. Welti, Ruth, and Wang, Xuemin. 2004. Lipid species profiling: A high throughput approach to
identify lipid compositional changes and determine the function of genes involved in lipid
metabolism and signaling. Curr. Opin. Plant Biol. 7, 337-344.
7. Welti, Ruth, Shah, Jyoti, LeVine, Steven, Esch, S. Wynn, Williams, Todd D., and Wang, Xuemin.
2005. High throughput lipid profiling to identify and characterize genes involved in lipid
metabolism, signaling, and stress response. In “Functional Lipidomics” (Chapter 14), L. Feng and
G.D. Prestwich, eds. Marcel Dekker, New York, pp. 307-322.
8. Wang, Xuemin, Li, Weiqi, Li, Maoyin, and Welti, Ruth. 2006. Profiling lipid changes in plant
response to low temperatures. Phys. Plantarum 126, 90-96.
9. Welti, Ruth, Isaac, Giorgis, Tamura, Pamela, Esch, Steven Wynn, Sparks, Alexis, Jeannotte,
Richard, Roth, Mary, Maatta, Sara, Williams, Todd D., Shah, Jyoti, and Wang, Xuemin. 2006.
Lipid profiling: Analysis of gene function and physiological responses in Arabidopsis. Proceedings
of the 17th International Symposium on Plant Lipids. Eds. Benning, Christoph and Ohlrogge,
John. pp. 287-291.
10. Welti, Ruth, Shah, Jyoti, Li, Weiqi, Li, Maoyin, Chen, Junping, Burke, John J., Fauconnier, MarieLaure, Chapman, Kent, Chye, Mee-Len, and Wang, Xuemin. 2007. Plant lipidomics: Discerning
biological function by profiling plant complex lipids using mass spectrometry. Frontiers in
Bioscience. 12, 2494-2506
11. Welti, Ruth, Roth, Mary R., Deng, Youping, Shah, Jyoti and Wang, Xuemin. 2007. Lipidomics:
ESI-MS/MS-based profiling to determine the function of genes involved in metabolism of complex
lipids. In “Plant Metabolomics”, Basil Nikolau. ed. Springer, Dordrecht, The Netherlands. pp. 8792.
23
12. Isaac, Giorgis, Jeannotte, Richard, Esch, Steven Wynn, and Welti, Ruth. 2007. New massspectrometry-based strategies for lipids, Gen. Eng. Rev. Vol. 28. 28, 129-157.
13. Wang, Xuemin (Sam), and Welti, Ruth. Understanding plant lipids. ASBMB Today. July 2009.
p. 22.
14. Li-Beisson, Y., Shorrosh, B., Beisson, F., Andersson, M., Arondel, V., Bates, P.D., Baud, S., Bird,
D., DeBono, A., Durrett, T.P., Franke, R.B., Graham, I.A., Katayama, K., Kelly, A., Larson, T.,
Markham, J.E., Miquel, M., Molina, I., Nishida, I., Rowland, O., Samuels, L., Schmid, K.M.,
Wada, H., Welti, R., Xu, C., Zallot R., and Ohlrogge J. 2010. Acyl lipid metabolism. The
Arabidopsis Book, 8, 1-65. http://www.bioone.org/doi/pdf/10.1043/tab.00133
15. Li-Beisson, Y., Shorrosh, B., Beisson, F., Andersson, M., Arondel, V., Bates, P.D., Baud, S., Bird,
D., DeBono, A., Durrett, T.P., Franke, R.B., Graham, I.A., Katayama, K., Kelly, A., Larson, T.,
Markham, J.E., Miquel, M., Molina, I., Nishida, I., Rowland, O., Samuels, L., Schmid, K.M.,
Wada, H., Welti, R., Xu, C., Zallot R., and Ohlrogge J. 2013. Arabidopsis Book. 11:e0161. doi:
10.1199/tab.0161. Epub 2013 Jan 29.
16. Welti, Ruth. 2010. Plant lipidomics. In The AOCS Lipid Library.
http://lipidlibrary.aocs.org/plantbio/plantlipidomics/index.htm
17. Samarakoon, Thilani*, Shiva, Sunitha* (* = equal contribution), Lowe, Kaleb, Tamura, Pamela,
Roth, Mary R., and Welti, Ruth. 2012. Arabidopsis thaliana membrane lipid molecular species and
their mass spectral analysis. In High throughput phenotyping in plants, Methods in Molecular
Biology. Ed., J. Normanly. Humana Press, New York, NY. 918, 179-268.
18. Shiva, Sunitha*, Vu, Hieu Sy* (*equal contributions), Roth, Mary R., Zhou, Zhenguo, Marepally,
Shantan Reddy, Nune, Daya Sagar, Lushington, Gerald H., Visvanathan, Mahesh, and Welti,
Ruth. 2013. Lipidomic analysis of plant membrane lipids by direct infusion tandem mass
spectrometry. In Plant Lipid Signaling Protocols, Methods in Molecular Biology. Ed. Teun Munnik
and Ingo Heilmann. Humana Press, New York, NY. 1009, 79-91.
19. Vu, Hieu Sy, Shiva, Sunitha, Hall, Aaron Smalter, and Welti, Ruth. (2013). A lipidomic approach
to identify cold-induced changes in Arabidopsis membrane lipid composition. In Plant Cold
Acclimation, Methods in Molecular Biology. Ed., D. Hincha. Humana Press, New York, NY. In
press.
Texts
1. Rintoul, David A., Welti, Ruth, Lederman, Muriel, Storrie, Brian and Van Buskirk, Robert. 1990.
A Student's Companion in Molecular Cell Biology, W. H. Freeman and Company/Scientific
American Books, New York.
2. Rintoul, D., Welti, R., Storrie, B., and Lederman, M. 1995. Student Companion for Molecular
Biology, Third Edition. W.H. Freeman and Company/Scientific American Books, New York.
24
Additional Publications* that Include Data from Lipid Analyses Performed at Kansas
Lipidomics Research Center: 2006-2013. (*Welti is not an author on these publications.)
1. Cruz-Ramirez, A., Oropeza-Aburto, A., Razo-Hernandez, F., Ramirez-Chavez, E., and Herrera-Estrella, L. 2006.
Phospholipase DZ2 plays an important role in extraplastidic galactolipid biosynthesis and phosphate recycling in
Arabidopsis roots. Proc. Natl. Acad. Sci. USA 103, 6765-6770.
2. Chen, J., Burke, J.J., Xin, Z., Xu, C., and Velten, J. 2006. Characterization of the Arabidopsis thermosensitive mutant
atts02 reveals an important role for galactolipids in thermotolerance. Plant, Cell and Environment 29, 1437-1448.
3. Kachroo, A., Shanklin, J., Whittle, E., Lapchyk, L., Hildebrand, D., and Kachroo, P. 2007. The Arabidopsis stearoylacyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis. Plant Mol. Biol. 63,
257-271.
4. Im, Y.J., Perera, I.Y., Brglez, I., Davis, A.J., Stevenson-Paulik, J., Phillippy, B.Q., Johannes, E., Allen, N.S., and Boss,
W.F. 2007. Increasing plasma membrane Phosphatidylinositol(4,5)Bisphosphate biosynthesis increases
phosphoinositide metabolism in Nicotiana tabacum. Plant Cell 19, 1603–1616.
5. Bates, P.D., Ohlrogge, J.B., and Pollard, M. 2007. Incorporation of newly synthesized fatty acids into cytosolic
glycerolipids in pea leaves occurs via acyl editing. J. Biol. Chem. 282, 31206-31216.
6. Xiao, S., Li, H.Y., Zhang, J.P., Chan, S.W., and Chye, M.L. 2008. Arabidopsis acyl-CoA-binding proteins ACBP4 and
ACBP5 are subcellularly localized to the cytosol and ACBP4 depletion affects membrane lipid composition. Plant
Mol. Biol. 68, 571-583.
7. Zhu, L., Liu, X., Liu, X., Jeannotte, R., Reese, J.C., Harris, M., Stuart, J.J., and Chen, M.-S. 2008. Hessian fly
(Mayetiola destructor) attack causes a dramatic shift in carbon and nitrogen metabolism in wheat. Mol. Plant-Microbe
Interact. 21, 70-78.
8. Regente, M., Corti Monzón, G., and de la Canal, L. 2008. Phospholipids are present in extracellular fluids of imbibing
sunflower seeds and are modulated by hormonal treatments. J. Exp. Botany 59, 553-562.
9. Cunningham, T.J., Yao, L., and Lucena, A. 2008. Product inhibition of secreted phospholipase A2 may explain
lysophosphatidylcholines' unexpected therapeutic properties. J. Inflamm. (Lond.). 5, 17.
10. Chen, M., Markham, J.E., Dietrich, C.R., Jaworski, J.G., and Cahoon, E.B. 2008. Sphingolipid long-chain base
hydroxylation is important for growth and regulation of sphingolipid content and composition in Arabidopsis. Plant
Cell 20, 1862-1878.
11. Chen, Q-F., Shi, X., and Chye, M.-L. 2008. Overexpression of the Arabidopsis 10-Kilodalton acyl-cCoenzyme Abinding protein ACBP6 enhances freezing tolerance. Plant Physiol. 148, 304–315.
12. Zhu, J., Mounzih, K., Chehab, E.F., Mitro, N., Saez, E., and Chehab, F.F. 2009. Effects of FoxO4 overexpression on
cholesterol biosynthesis, triacylglycerols accumulation and glucose uptake. J. Lipid. Res. 51, 1312-1324.
13. Zufferey, R., Al-Ani, G.K., and Dunlap, K. 2009. Leishmania dihydroxyacetonephosphate acyltransferase LmDAT is
important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes. Mol. Biochem.
Parasitol. 168, 177-185.
14. Zhang, Q., Fry, J., Rajashekar, C., Bremer, D., and Engelke, M. 2009. Membrane polar lipid changes in zoysiagrass
rhizomes and their potential role in freezing tolerance. J. Am. Soc. Hort. Sci. 134, 322-328.
15. Xia, Y., Gao, Q., Yu, K., Lapchyk, L., Navarre, D., Hildebrand, D., Kachroo, A., and Kachroo, P. 2009. An intact
cuticle in distal tissues is essential for the induction of systemic acquired resistance in plants. Cell Host & Microbe, 5,
151-165.
16. Regente, M., Corti-Monzón, G., Maldonado, A.M., Pinedo, M., Jorrín, J., de la Canal, L. 2009. Vesicular fractions of
sunflower apoplastic fluids are associated with potential exosome marker proteins. FEBS Lett. 2583, 3363-3366.
17. Reina-Pinto, J. J., Voisin, D., Kurdyukov, S., Faust, A., Haslam, R.P., Michaelson, L.V., Efremova, N., Franke, B.,
Schreiber, L., Napier, J.A., and Yephremov, A. 2009. Misexpression of FATTY ACID ELONGATION1 in the
Arabidopsis epidermis induces cell death and suggests a critical role for phospholipase A2 in this process. Plant Cell
21, 1252-1272.
25
18. Keogh, M.R., Courtney, P.D., Kinney, A.J., and Dewey, R.E. 2009. Functional characterization of phospholipid Nmethyltransferases from Arabidopsis and soybean. J. Biol. Chem. 284, 15439-15447.
19. Kirik, A., and Mudgett, M.B. 2009. SOBER1 phospholipase activity suppresses phosphatidic acid accumulation and
plant immunity in response to bacterial effector AvrBsT. Proc. Natl. Acad. Sci. U S A 106, 20532-20537.
20. Hafer, A., Whittlesey, R., Brown, D.T., and Hernandez ,R. 2009. Differential incorporation of cholesterol by sindbis
virus grown in mammalian or insect cells. J. Virol. 83, 9113-9121.
21. Burow, G.B., Franks, C.D., Acosta-Martinez, V., and Xin, Z. 2009. Molecular mapping and characterization of BLMC,
a locus for profuse wax (bloom) and enhanced cuticular features of sorghum (Sorghum bicolor (L.) Moench.). Theor
Appl Genet. 118, 423-431.
22. Cherian, G., 2009. Egg yolk conjugated linoleic acid alters phospholipid molecular species in chick tissues. European
J. Lipid Sci. Tech. 111, 546-552.
23. Coronado, M., Yuan, W., Wang, D., and Dowell, F.E. 2009. Biodiesel-diesel blends using near-infrared spectroscopy.
Applied Engineering in Agriculture 25, 217-221.
24. Cunningham, T.J., Yao ,L., Lucena, A., and Greenstein, J.I. 2009. Uncompetitive phospholipase A2 inhibition by
CHEC sequences including oral treatment of experimental autoimmune myeloencephalitis, Open Enzyme Inhibition J.
2, 1-7.
25. Finnie, S.M., Jeannotte, R., and Faubion, J.M. 2009. Quantitative characterization of polar lipids from wheat wholemeal, flour and starch. Cereal Chem. 86, 637–645.
26. Yalcin, A., Clem, B., Makoni, S., Clem, A., Nelson, K., Thornburg, J., Siow, D., Lane, A.N., Brock, S.E.,
Goswami, U., Eaton, J.W., Telang, S., and Chesney, J. 2010. Selective inhibition of choline kinase simultaneously
attenuates MAPK and PI3K/AKT signaling. Oncogene 29, 139–149.
27. Yergeau, E., Labour, K., Hamel, C., Vujanovic, V., Nakano-Hylander, A., Jeannotte, R., and St-Arnaud, M. 2010.
Patterns of Fusarium community structure and abundance in relation to spatial, abiotic and biotic factors. FEMS
Microbiol. Ecol. 71, 34-42.
28. Yu, L., Nie, J., Cao, C., Jin, Y., Yan, M., Wang, F., Liu, J., Xiao, Y., Liang, Y., and Zhang, W. 2010. Phosphatidic acid
mediates salt stress response by regulation of MPK6 in Arabidopsis thaliana. New Phytol. 188, 762–773.
29. Zhu, L., Liu, X., and Chen, M.-S. 2010. Differential accumulation of phytohormones in wheat seedlings attacked by
avirulent and virulent Hessian fly (Diptera: Cecidomyiidae) larvae. J. Econ. Entomol. 103, 178-185.
30. Zhu, J., Mounzih, K., Chehab, E.F., Mitro, N., Saez, E., and Chehab, F.F. 2010. Effects of FoxO4 overexpression on
cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake. J. Lipid Res. 51, 1312-1324.
31. Wen, D., Androjna, C., Vasanji, A., Belovich, J., and Midura, R.J. 2010. Lipids and collagen matrix restrict the
hydraulic permeability within the porous compartment of adult cortical bone. Ann. Biomed. Engin. 38, 558-569. DOI:
10.1007/s10439-009-9858-z
32. Smith, C.M., Liu, X., Wang, L.J., Liu, X., Chen, M.S., Starkey, S., and Bai, J. 2010. Aphid feeding activates
expression of a transcriptome of oxylipin-based defense signals in wheat involved in resistance to herbivory. J. Chem.
Ecol. 36, 260-276.
33. Shen, W., Li, J.Q., Dauk, M., Huang, Y., Periappuram, C., Wei, Y., and Zou, J. 2010. Metabolic and transcriptional
responses of glycerolipid pathways to a perturbation of glycerol 3-phosphate metabolism in Arabidopsis. J. Biol. Chem.
285, 22957-22965.
34. Du, Z.Y., Xiao, S., Chen, Q.F., and Chye, M.L. 2010. Depletion of the membrane-associated acyl-coenzyme A-binding
protein ACBP1 enhances the ability of cold acclimation in Arabidopsis. Plant Physiol. 152, 1585-1597.
35. Edelstein, C., Pfaffinger, D., Yang, M., Hill, J.S., and Scanu, A.M. 2010. Naturally occurring human plasminogen,
like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts. Biochim. Biophys. Acta.
1801, 738-745.
36. Finnie, S.M., Jeannotte, R., Morris, C.F., and Faubion, J.M. 2010. Variation in polar lipid composition among nearisogenic wheat lines possessing different puroindoline haplotypes. J. Cereal Sci. 51, 66-72.
37. Finnie, S.M., Jeannotte, R., Morris, C.F., Giroux, M.J., and Faubion, J.M. 2010. Variation in polar lipids located on the
surface of wheat starch. J. Cereal Sci. 51, 73-80.
26
38. Gallier, S., Gragson, D., Jiménez-Flores, R., and Everett, D.W. 2010. Using confocal laser scanning microscopy to
probe the milk fat globule membrane and associated proteins. J. Agric. Food Chem. 58, 4250–4257.
39. Gallier, S., Gragson, D., Cabral, C., Jiménez-Flores, R., and Everett, D.W. 2010. Composition and fatty acid
distribution of bovine milk phospholipids from processed milk products. J. Agric. Food Chem. 58, 10503–10511.
40. Grim, J.M., Miles, D.R.B., and Crockett, E.L. 2010. Temperature acclimation alters oxidative capacities and
composition of membrane lipids without influencing activities of enzymatic antioxidants or susceptibility to lipid
peroxidation in fish muscle. J. Exp. Biol 213, 445-452.
41. Castorena, K.M., Stapleford, K.A., and Miller, D.J. 2010. Complementary transcriptomic, lipidomic, and targeted
functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock
House virus RNA replication. BMC Genomics 11, 183. doi:10.1186/1471-2164-11-183
42. Chen, H., and Xiong, L. 2010. myo-Inositol-1-phosphate synthase is required for polar auxin transport and organ
development. J. Biol. Chem. 285, 24238-24247.
43. Chen, J., Xu, W., Burke, J.J., and Xin, Z. 2010. Role of phosphatidic acid in high temperature tolerance in maize. Crop
Sci. 50, 2506-2515.
44. Chen, M., and Thelen, J.J. 2010. The plastid isoform of triose phosphate isomerase is required for the postgerminative
transition from heterotrophic to autotrophic growth in Arabidopsis. Plant Cell 22, 77-90.
45. Chen, Q.-F., Xiao, S., Qi, W., Mishra, G., Ma, J., Wang, M., and Chye, M.-L. 2010. The Arabidopsis acbp1acbp2
double mutant lacking acyl-CoA-binding proteins ACBP1 and ACBP2 is embryo lethal. New Phytol. 186, 843–855.
46. Zhang, J., Martin, J.M., Beecher, B., Lu, C., Hannah, C., Wall, M.L., Altosaar, I., and Giroux, M.J. 2010. The ectopic
expression of the wheat Puroindoline genes increase germ size and seed oil content in transgenic corn. Plant Mol. Biol.
74, 353–365
47. Kim, H.U., Vijayan, P., Carlsson, A. S., Barkan, L., Browse, J. 2010. A mutation in the LPAT1 gene suppresses the
sensitivity of fab1 plants to low temperature. Plant Physiol. 153, 1135-1143.
48. Biller, S.J., Wayne, K.J., Winkler, M.E., and Burkholder, W.F. 2011. The putative hydrolase YycJ (WalJ) affects the
coordination of cell division with DNA replication in Bacillus subtilis and may play a conserved role in cell wall
metabolism. J. Bacteriol. 193, 896-908.
49. Hameed, S., Dhamgaye, S., Singh, A., Goswami, S.K., Prasad, R. 2011. Calcineurin signaling and membrane lipid
homeostasis regulates iron mediated multidrug resistance mechanisms in Candida albicans. PLoS ONE 6(4): e18684.
50. Liegel, R., Chang, B. Dubielzig, R., and Sidjanin, D.J. 2011. Blind sterile 2 (bs2), a hypomorphic mutation in Agps,
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51. Friederichs, J.M., Ghosh, S., Smoyer, C.J., McCroskey, S., Miller, B.D., Weaver, K.J., Delventahl, K.M., Unruh, J.,
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52. Myers, A.M., James, M.G., Lin, Q., Yi, G., Stinard, P.S., Hennen-Bierwagen, T.A., and Becraft, P.W. 2011. Maize
opaque5 encodes monogalactosyldiacylglycerol synthase and specifically affects galactolipids necessary for amyloplast
and chloroplast function. Plant Cell. 23, 2311-2347.
53. Merath, K., Chang, B., Dubielzig, R., Jeannotte, R., and Sidjanin, D.J. 2011. A spontaneous mutation in Srebf2 leads to
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54. Chrisman, C.J., Albuquerque, P., Guimaraes, A.J., Nieves, E., and Casadevall, A. 2011. Phospholipids trigger
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55. Zhai, S.-M., Gao, Q., Xue, H.-W., Sui, Z.-H., Yue, G.-D., Yang, A.-F., and Zhang, J.R. 2011. Overexpression of the
phosphatidylinositol synthase gene from Zea mays in tobacco plants alters the membrane lipids composition and
improves drought stress tolerance. Planta 235, 68-84.
56. Alawode, O.E., Robinson, C., and Rayat, S. 2011. Clean photodecomposition of 1-methyl-4-phenyl-1h-tetrazole-5(4h)thiones to carbodiimides proceeds via a biradical. J. Org. Chem., 76, 216–222.
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J. Cell Sci. 124, 3223-3234.
59. Chanda, B., Xia, Y., Mandal, M.K., Yu, K., Sekine, K.T., Gao, Q., Selote, D., Hu, Y., Stromberg, A., Navarre, D.,
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69. Zhu, L., Chen, M.-S., and Liu, X. 2011. Changes in phytohormones and fatty acids in wheat and rice seedlings in
response to Hessian fly (Diptera: Cecidomyiidae) infestation. J. Econ. Entomol. 104, 1384-1392.
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