Kansas State University
Department of Chemistry
This presentation will provide you with information
about some of the many different research topics
that we offer.
Feel free to take a virtual trip through our
Department (use the slide show option) and do not
hesitate to contact us if you have any questions or
comments.
Prof. Aakeröy: aakeroy@ksu.edu or 785-532 6096
Going to graduate School?
How about Kansas State University?
You can make new molecules...
...or study their properties.
Aufsicht
Several focus areas
Asymmetric catalysis
Biophysical chemistry
Drug design in theory
and practice
Bioanalytical chemistry
and chemical sensors
Materials science and
nanotechnology
Structure and bonding
Supramolecular chemistry and crystal engineering
Electronic structure
Biological sensors
Quantum chemistry
Biophysical
chemistry
Chemical separation
Ultrasensitive microscopy
Single-molecule spectroscopy
Professor Christine Aikens
Quantum chemistry
Application of electronic structure methods to:
Nanoparticles
Nanostructured materials
Complex intermetallics
Quasicrystals
To investigate:
Optical properties
Interparticle interactions
Growth mechanisms
Design and programming of
efficient algorithms in the
GAMESS program
Nanostructured Materials
Control over assembly of nanoparticles is
primary obstacle to bottom-up construction of
novel materials and devices
Goals:
Understand the interactions between
nanoscale building blocks
Achieve control over these interactions
Elucidate how certain types of interactions
lead to specific target structures
Self-assembly of
colloidal crystals
Binary nanoparticle
superlattices
Shevchenko, E. V. et al.
Nature 2006, 439, 55.
Murray, C. B. et al. Science 1995, 270, 1335.
Aikens Group
Complex Intermetallics
Complex intermetallic icosahedral alloys
– Excellent long-range order but no periodicity
How do these structures form?
– Cluster-by-cluster
– Atom-by-atom
Goals:
• Explain stability of gas-phase clusters
• Determine structural motifs in these clusters
• Examine the atom-by-atom growth mechanism
in order to determine its viability
icosahedral Zn-Mg-Dy
Aikens Group
Professor Viktor Chikan
Physical Chemistry and Material Chemistry
Research Interest
Physical chemistry of nanostructuresoptical,
electrical
properties
and
thermodynamics of doped quantum confined
semiconductor systems
Synthesis of Doped Nanostructures
Controlling the conductivity (carrier density, carrier
mobility) in quantum confined semiconductor devices is
important for future applications. We are developing
synthetic methods of creating doped quantum dots. In
addition, we are interested in doping intrinsically
anisotropic (such as GaSe quantum dots) and
extrinsically anisotropic quantum confined systems (e.g.
CdSe quantum rods).
Time-domain Terahertz Spectroscopy of Doped Nanostructures
Measuring the
conductivity of the
doped nanostructures is
challenging because of
the difficulty to
connecting them to
external circuitry.
Terahertz radiation
generated by an
ultrafast laser provides
a convenient way to
measure the frequency
dependant complex
conductivity of the
doped nanostructures.
1 THz = 300 µm = 33 cm-1 = 4.1 meV
Ultrafast Carrier Dynamics
(Time-resolved Terahertz Spectroscopy)
While Time-domain
Terahertz Spectroscopy
offers a way to probe the
equilibrium conductivity
of the doped system,
Time-resolved Terahertz
Spectroscopy provides a
way to measure the
transient conductivity in
doped quantum dots, pn junctions and 3D
quantum Wells.
Professor Christopher Culbertson
Bioanalytical Chemistry Separations, Microfluidics, and Cell Analysis
We
are
interested
in
developing new separation
and
sample
handling
components for microfluidic
(Lab-on-a-Chip) devices and
then using these devices to
solve interesting bioanalytical
problems.
These devices may facilitate 1) the early diagnosis and successful
treatment of diseases like cancer, and 2) a better understanding
how complex organisms develop from single cells.
Prof. Christopher Culbertson
Buffer
Sample
Waste
SW
5.08 cm
High Efficiency Separations
G
Q
P
3.0
2.5
Single Cell
Analysis
E
D
10mM Borate/50mM SDS w/ 10% i-PA
l = 11.84 cm; Esep = 740 V/cm
T
A
S
2.0
Y
M
N
1.5
I
L
F
V
1.0
K
K
0.5
W
R
C
0.0
70
80
90
100
110
120
130
Elution time (sec)
140
150
160
170
Professor Dan Higgins
Analytical Chemistry, Materials Chemistry, Optical
Microscopy and Spectroscopy
Single Molecule Spectroscopy
Near-field Scanning Optical Microscopy (NSOM)
1. High Resolution Optical Microscopy Studies of
Liquid-Crystal/Polymer Composites
Multiphoton Excited Fluorescence Microscopy
Conventional
Fluorescence
Two Photon Excitation
Near-Field Optical Microscopy
125 µm
Optical
Fiber
Aluminum
100 nm
<< l ( 5 nm)
Near Field
Sample
Far Field
Detector
Higgins Group
Funding: NSF-CHE/DMR
ONR: Photovoltaics
2.Polymer/LC Composites: Order LC Droplet Arrays and
Photorefractive Materials
NSOM Imaging: Photorefractive LCs
Multiphoton Excited Fluorescence:
Hexagonal LC Droplet Arrays
4 µm
Topography
Birefringence
4 µm
Fluorescence
Asymmetric Laser Beam Diffraction
Pu
Pr
2 µm
Hall and, Higgins, J. Phys. Chem, in press.
Higgins Group
Luther, Springer, Higgins, Chem. Mater., 2001, 13, 2281.
3. Organic Photovoltaics:
Self-Assembly of New Solar
Cell Materials
N(CH3)3+
O
N
O
O
N
O
X-
Fluorescence
Dye/Polymer
Composites
1200
Domain Organization
1100
C12-PDI+
1000
900
0
Higgins
HigginsGroup
Group
50
100
150
Polarization (degrees)
Professor Takashi Ito
Analytical Chemistry (Chemical Sensing), Electrochemistry,
Self-Organized Nanostructural Materials, Nanofluidics
Our Research Interests:
1. Synthesize and characterize novel selforganized nanostructural materials
with uniform domain morphologies.
2. Clarify molecular-level mass- and
charge-transport within the nanoscale
domains.
3. Apply these materials for chemical
sensing, separations and energy-related
technologies.
Preparation and Characterization of Nanoporous Materials
• Design and prepare monolithic materials comprising an array of
self-organized cylindrical nanopores with uniform pore sizes.
• Characterize the properties of nanopores using electrochemical,
spectroscopic and microscopic techniques.
Anodic nanoporous metal oxides
Block copolymers
Electrochemical
characterization
1) T. Ito, A. A. Audi, G. P. Dible Anal. Chem. 2006, 78, 7048.
2) Y. Li, H. C. Maire, T. Ito Langmuir 2007, 23, 12771.
3) Y. Li, T. Ito Langmuir 2008, 24, 8959.
4) H. C. Maire, S. Ibrahim, Y. Li, T. Ito Polymer 2009, 50, 2273.
5) D. M. N. T. Perera, T. Ito Analyst 2010, 135, 172.
6) F. Li, R. Diaz, T. Ito RSC Adv. 2011, 1, 1732.
7) S. Ibrahim, S. Nagasaka, D. S. Moore, D. A. Higgins, T. Ito ECS Trans. 2012, 41, 1.
8) B. Pandey, P. Thapa, D. A. Higgins, T. Ito Langmuir 2012, 28, 13705.
Applications of Nanoporous Materials
1. Fundamental Studies on MassTransport within Nanodomains
• Single-molecule spectroscopy
(in collaboration with Prof. Higgins)
1) K. H. Tran Ba, T. A. Everett, T. Ito, D. A. Higgins Phys.
Chem. Chem. Phys. 2011, 13, 1827.
2) A. W. Kirkeminde, T. Torres, T. Ito, D. A. Higgins J. Phys.
Chem. B 2011, 115, 12736.
3) S. C. Park, T. Ito, D. A. Higgins J. Phys. Chem. B in press.
4) K.-H. Tran-Ba, J. J. Finley, D. A. Higgins, T. Ito J. Phys.
Chem. Lett. 2012, 3, 1968.
2. Chemical Sensing with
Cylindrical Nanodomains
• Uniform pore sizes and shapes
size-selective sensing media
• Controllable surface chemistry
chemically selective sensing media
1) Y. Li, T. Ito Anal. Chem. 2009, 81, 851.
2) S. Ibrahim, T. Ito Langmuir 2010, 26, 2119.
3) T. Ito, I. Grabowska, S. Ibrahim Trends Anal. Chem. 2010, 29, 225.
4) D. M. N. T Perera, B. Pandey, T. Ito Langmuir 2011, 27, 11111.
5) B. Pandey, K. H. Tran Ba, Y. Li, R. Diaz, T. Ito Electrochim. Acta
2011, 56, 10185.
6) F. Li, B. Pandey, T. Ito Langmuir, submitted.
Professor Jun Li
Analytical Chemistry and Materials Chemistry
Research Interest
The growth and characterization of nanowire
materials (carbon nanotubes/nanofibers, inorganic
semiconducting or metal nanowires), the fabrication
and integration of nanowire materials into solid-state
micro/nano- devices, and the development of novel
nanodevices (particular electronic devices) for
analytical and biomedical applications.
Goal
Our goal is to develop new biosensors and
nanobiotechnologies for environmental, security, and
biomedical applications through the innovation in
nanomaterials growth and device integration and
collaboration with industries and government
agencies.
Plasma Enhanced Chemical Vapor
Deposition
Graphite
SWNT
MWNT
Carbon Nanofibers
Nanotechnology Platforms Based on
Vertically Aligned Nanowires
Electrical
Mechanical
Biomimetic Dry Adhesives
Electrical
MWCNT/CNF
Electrical
Ultrasensitve Nucleic
Acid Detection
E. Coli
Thermal &
Mechanical Inorganic Nanowires
Nanoscale IC Interconnects
Thermal Interface Materials
Electronic
Vertical Nanoelectronics
and nanophotonics
Electrical
Ultrasensitive Immunosensor
Neural Electrical Interface
Fabrication of Carbon Nanofiber Nanoelectrode
Arrays for Biosensing
As-grown CNF arrays
Micropatterned
2 mm
30 dies on a 4” wafer
50 mm
Nanopatterned
200 mm
A 3x3 microelectrode
5 mm
carbon nanofiber arrays
on each microelectrode
Nonpatterned
J. Li, et al, Nanoletters, 3(5), 597-602 (2003).
J. Li, et al, Appl. Phys. Lett., 82(15), 2491 (2003).
J. Koehne, et al., Clinic. Chem. 50:10, 1886 (2004).
500
nm
Inlaid CNF arrays in SiO2
Professor Ryszard Jankowiak
Physical, biophysical, and analytical chemistry
Photosynthesis
Research
Cancer
Research
N1
Photosynthesis Research
Solar energy driven
primary events of
photosynthesis; molecular
electronics…
The primary events of interest are excitation energy transfer and
charge separation, both of which involve arrays of interacting
chlorophyll molecules and other cofactors that are held in strategic
positions by protein scaffolding.
Cancer Research
Understanding the activity of
carcinogens, structure of DNA
adducts, and development of
advanced biomonitoring
techniques
for cancer risk assessment…
Develop novel methods/devices for screening estrogen-derived DNA
adducts, conjugates, and metabolites in human samples
 immunoaffinity biosensor columns with imaging capabilities…
 innovative MAb-based biosensors on glass, polymer, and/or silicon wafer
substrates with multiple addressable patches on the surface designed and built
for detection of CEQ-derived biomarkers
Detection will be based on a novel “first-come-first-served” approach and
fluorescence based imaging. Human samples to be studied include: urine, serum,
and tissue extracts obtained from human breast and prostate cancer patients…
Professor Paul Smith
Biophysical chemistry
Co-solvent effects on peptides
and proteins.
Modeling of opioid peptides and
their receptors.
Computer simulation of the structure
and dynamics of peptides, proteins
and nucleic acids.
The general focus of the group is the study of the effects of solvent and
cosolvents on the structure and dynamics of biomolecules in solution. Our
main tool is molecular dynamics simulations which are used to provide
atomic level detail concerning the properties of these molecules.
Our current research is focused in several areas
Cosolvent Effects on Peptides and Proteins
Why do urea and gdmcl denature proteins?
How does trifluoroethanol induce helix structure?
What does the denatured state of a protein look like?
Opioid peptides and delta-opioid receptor modeling
What does the delat-opioid receptor look like?
What is the active conformation of receptor agonists?
What is the conformational change of the receptor on activation?
Improved force field parameters
How can we improve our ideas of how atoms/molecules interact?
Opioid peptides and delta-opioid receptor
modeling
Opioids are small peptides that play a major role in
our response to pain. The design of improved and
non addictive new pain killing drugs depends on an
understanding of the interaction between opioids
and their receptor. The exact site of opioid peptide
binding to the receptor is unknown. We have
recently developed a model for the delta-opioid
receptor (see right) which can be used to probe the
interactions between potential drug molecules and
the receptor.
By simulating the conformational preferences
of known delta-opioid receptor agonists one
can speculate on the bioactive conformation
of the peptides required for receptor activation
(see left for Deltorphin I).
Organometallic chemistry
New catalysts
Molecular magnets
Nanoparticles
Zeolite mimics
Environmental protection
Supramolecular chemistry
Professor Christer Aakeröy
Supramolecular synthesis and structural chemistry
Fundamental crystal engineering
Design of functional solids
Supramolecular synthesis
Molecular sociology
Interactions between
molecules control...
Key steps in supramolecular synthesis
Recognition
…the bouquet of wine,...

Binding
This needs to be achieved
without making or breaking
any covalent bonds!
We use hydrogen bonds and
Organization halogen bonds as molecular
‘glue’ for linking different
building blocks into predictable
architectures.

…the ability of a drug to
block an enzyme,...

O
Function
H
O
R
R
O
H
H
O
O
N
R
R
N
H
…and the formation of
thunder clouds.
H
H
R
O
N
N
H
H
O
H
R
H
O
1.
Supramolecular inorganic chemistry (NSF support)
L
L
M
L
L
L
M
L
L
M
L
M=Pt, Pd, Ni ,Cu(I)
L
L M L
L
L
Porous materials and
nanoparticles.
M=Ru, Ir, Rh, Fe, Co
3-D
2-D
2.
Supramolecular organic chemistry (NSF support)
Molecular capsules
Ternary cocrystals
(SR)
Solubility studies of HMBA @ 24hrs
Pharmaceutical chemistry (Industry Support)
Why compounds fail or slow down in development
0.4500
0.4000
0.3500
S (mg/mL)
3.
0.5000
0.3000
0.2500
0.2000
0.1500
0.1000
0.0500
0.0000
We have shown that cocrystals of anti-cancer agents
can improve properties such
as solubility.
4,4-HMBA
HMBA + Suc
HMBA + Adip
HMBA + Sub
HMBA + Seb
API & Cocrystal
Aqueous solubility of the drug can be modulated!
The solubility can be increased or decreased
compared to that of the drug itself.
Professor Chris Levy
Organometallic chemistry and catalysis
Our
primary
interests
are
the
development of new stereospecific
catalysts for organic transformations and
polymerizations and the investigation of
organometallic structure and mechanism.
OH
[O]
R1
R2
R1
We are creating new helical
transition metal catalysts for
the following asymmetric
transformations:
R2
R3
R1
R1
[O]
R4
S
[O]
R2
R2
O
R1
R3
R2
R4
O
R1
S
R2
Some new helical complexes and their structures.
N
N
+ FeCl2
OH HO
NaOMe, 25ûC
Toluene, EtOH
20h r.t.
N
Fe
N
O O
HH
H
H
HH
N
N
OH HO
+ ZnCl2
NaOMe , 25ûC
N N
Zn
O O
Professor Eric Maatta
eam@ksu.edu
Synthetic Inorganic and Materials Chemistry
Polyoxometalate clusters
Multinuclear NMR studies
Metal-ligand multiple bonds
Transition metal catalysis
Hybrid materials
really big molecules
A couple of our favorites . . .
A soluble polystyrene incorporating a
redox-active polyoxometalate cluster
A nitrido-polyoxometalate:
[(OsVIN)P2W17O61]7-
Professor Emily McLaurin
Inorganic Chemistry and Materials Chemistry
Sensing of biological analytes
Heterostructures for catalysis
New materials for solar light harvesting
Energy transfer and charge transfer at interfaces
Material surfaces and interfaces
Surface chemistry plays a critical role
in the properties of nanomaterials.
Changing the material surface adjusts
the particle solubility, conductivity,
stability, and luminescence among
other properties.
Doped materials for ratiometric sensing
+ analyte
Synthesis of new transition
metal-doped semiconductor
nanomaterials allows for
exploration of new sensing
mechanisms using dopant
related properties. The dopant
also acts as a probe of the
semiconductor surface.
New materials for light harvesting and catalysis
Charge separation in semiconductor
nanomaterials can be improved by
formation of hetero- and asymmetric
structures as well as alternative
morphologies.
Asymmetry
New morphologies
Materials that absorb a large part of
the solar spectrum are often easily
oxidized. Stability can be enhanced
using new structures and materials.
Heterostructures
Examination of energy and charge transfer
processes affecting hybrid organic-semiconductor
and metal-semiconductor systems can improve
solar conversion and storage efficiencies.
Total synthesis
Proteins and peptides
Anti-cancer drugs
Host-guest chemistry
Ferroelastic materials
Regioselective catalysis
Professor Stefan Bossmann
Organic, Bioinorganic and Materials Chemistry
Stem Cell
Identification
Optical Tomography
Tumor Imaging
Professor Stefan Bossmann
Organic, Bioinorganic and Materials Chemistry
Synthesis of Fe(0)-Nanoparticles for Tumor Imaging,
Hyperthermia Treatment of Cancer and Catalytic Applications
Professor Stefan Bossmann
Organic, Bioinorganic and Materials Chemistry
Stem Cells and Defensive Cells take up of Fe(0)-nanoparticles and
transport them to tumors thus permitting cell-based cancer therapy.
A: Melanoma in a Black Mouse; B: Stem Cells (red) travel to the
location of tumors/metastases
This work is performed in close collaboration with Prof. Dr. Deryl L.
Troyer, Department of Anatomy&Physiology
Professor Mark Hollingsworth
Physical-Organic and Solid-State Organic Chemistry
Probing the elastic properties of materials - studies of
ferroelastic and ferroelectric domain switching
Domain switching is an important phenomenon in
technological devices, but it also can be used as a
tool to understand how elastic properties of
crystals are affected by internal molecular
structures, impurities and defect structures.
2,10-Undecanedione/urea crystals contain
ferroelastically distorted domains that are
twinned across two types of boundaries
to give as many as twelve sectors.
As a complement to SWBXT,
birefringence mapping using the
Metripol microscope gives both
after stress
before stress
indicatrix orientation (upper) and
Synchrotron white beam X-ray
optical retardation (lower) and
Pure crystals of this material topography (SWBXT) images
reveals disorder both within and
undergo irreversible (plastic) taken before and after stress for
between domains, especially at
domain reorientation (above), crystals containing 10% (top), 14% boundaries that show epitaxial
but 2-undecanone impurities (middle) and 18% 2-undecanone
mismatches.
can make this process elastic. (bottom) show that impurities
(See videos on the next page.) unpin stressed defect sites and
make domain switching reversible.
By generating a large series of ferroelastic inclusion compounds that are closely related to each other,
and then comparing domain switching in these crystals as a function of impurities, it is possible to show
that the impurities control the dynamics and reversibility of domain switching by breaking up cooperative
hydrogen bonding networks and unpinning stressed sites in these crystals.
Ferroelectric domain switching in inclusion
compounds of tetra-t-butylcalix[4]arene
O
O
N
-
+
+
N
Host structure
In an electric field, the guests rotate
about the pseudo-fourfold axis of the host
X
X
X
Y
Y
X
Y
X
Z
Z(X')
X
Which of the above guests could show
ferroelectric domain switching?
O-
Professor Duy H. Hua
Synthesis and Bio-evaluation of Natural and Unnatural Products,
Design of Enzyme Inhibitors, and Syntheses of Beltenes and
Nanomaterials
Anti-cancer agents targeting
Gap junction intercellular
communication
Development of new stereo-selective reactions
Synthesis of nanogels for selective drug delivery
Duy H. Hua
Two major research projects are being carried out in our
group, and they are: synthesis, mechanism, and
bioevaluation of biologically active compounds and
syntheses and applications of beltenes and nanomaterials.
O
Bioactive
Compounds
CH3
OAr
RO
H
CO2H
O
H
O
O
H
O
Myriceric Acid A
for release of vasospasm
Releasing of blood vessel
N
OH
OH
Biophysical Analyses
O
N
NH2
N
R'HN
N
Quinolines for gap junction
N
A Tricyclic Pyrone Adenine intercellular communication
for disaggregation of A42
oligomers
Surface Plasmon Resonance of
A and CP2
Gap junction channel and PQ1
Duy H. Hua
R2
R1
R1
R2
R2
Synthetic targets
R2
R1
R
1
R2
R1
R
R
R
R1
R2
1
2
R2
1
R2
R1
1
R
R2
R2
R1
R2
R1
[12]Cyclacenes
10.64 Å
9.71 Å
Armchair Carbon nanotube
Atomic force microscopic
images of functionalized
carbon nanotubes
1H-15N-HSQC
peptide
Bar is 0.5 mm.
spectrum of A40
Professor Ping Li
Chemical Biology/Bioorganic Chemistry
Research Interests
Use synthetic organic chemistry
and molecular biology as major
tools to study and manipulate
biologically
important
enzymes/proteins. Currently, I
have four projects in my lab.
1. Studies of ghrelin acylation by ghrelin
O-acyltransferse (GOAT).
GOAT was recently discovered1-2 as a potential drug target
for curing obesity. We will investigate its molecular
mechanisms and design effective inhibitors to it.
1. Gutierrez, J. A.; Solenberg, P. J.; Perkins, D. R.; Willency, J. A.; Knierman, M. D.; Jin, Z.;
Witcher, D. R.; Luo, S.; Onyia, J. E.; Hale, J. E. Proc. Natl. Acad. Sci. USA 2008, 105, 6320.
2. Yang, J.; Brown, M. S.; Liang, G.; Grishin, N. V.; Goldstein, J. L. Cell 2008, 132, 387.
2. Mechanistic studies of polyhydroxyalkonate (PHA) biosynthesis.
Commercial products made of PHA
Biodegradable plastic PHAs can substitute oil-based
plastics that are non-biodegradable. Our ultimate
goal is to understand mechanisms of proteins
involved in PHA biosynthesis and to engineer them
to produce PHAs in an economically competitive
fashion, which will help to protect our environment
and save energy.
3. Investigation of peptidoglycan glycosyltransferases (PGTs) in peptidoglycan
biosynthesis.
PGT catalyze the final step of polymerizing Lipid II to
form the nascent bacterial wall. Because their function
is unique and essential for bacterial survival, PGTs
have been the major target of clinically used
antibiotics. Our goals are to understand the
mechanism of substrate recognition by PGTs, to
develop a model that can predict interactions between
PGTs and substrate, and to design novel inhibitors to
PGTs.
4. Site-specific protein labeling using SNAP tag.
Selective labeling of proteins has become an essential tool to
visualize and characterize biological activities inside living cells.
The SNAP tag was first introduced by Kai Johnsson using a human
O6-alkylguanine-DNA alkyltransferase (hAGT), which transfers the
alkyl group from its substrate, O6-alkylguanine-DNA to one of its
cysteine residues. Our goals are to develop novel small molecule
probes for specific labeling and apply this technology for detection
of protein-protein interactions.
Professor Ryan J. Rafferty
Organic Chemistry & Chemical Biology
Total Synthesis
Development of Selective
Drug Delivery Systems
Drug Discovery
and Evaluation
Structurally Remodeling for Library Construction
Blood-Brain Barrier Penetration
Investigation, Enhancement, and Therapeutic
Total Synthesis, Structurally Remodeling for Library
Construction, Drug Discovery and Evaluation
Total Synthesis Campaigns of Biologically
Interesting Compounds
Structural Remodeling of Natural Products
and Complex Intermediates
Library Construction
Screening Campaigns of Synthesized
Compounds
Biochemical and Molecular Biology
Medicinal Chemistry
Discovery of New Drug Candidates
Rafferty Research Group
Blood-Brain Barrier Penetration
Investigation, Enhancement, and Therapeutic
Synthesis of Chemical Library Probing
Varying Chemo-physical Properties via
Ring Closing Metathesis, Diels-Alder &
Peripheral Modification reactions
Evaluation of Compounds Upon Blood
Brain Penetration
Nature Reviews Drug Discovery 2007, 6, 650-661
Library Construction
Elaboration of Scaffolds and Evaluation against various diseases
Rafferty Research Group
Development of Selective Drug Delivery Systems
Targeting Folate Receptors due to OverExpression within Cancers and Acidic
Microenvironments
Enhancement of Drugs to Reduce Off-Target
Side Effects
Evaluation of system in vitro/vivo
Rafferty Research Group
A few more reasons to consider Graduate
studies in Chemistry at Kansas State:
• Competitive stipends.
• An expanding and well-funded Department.
• First-rate research in inorganic, organic,
physical, analytical, materials, and biological
chemistry.
• Friendly and helpful staff and faculty.
• Our graduate students have successful careers
(see next few pages for some examples)!
Gregory Roman (Ph. D.
2006)
Assistant Professor
Bryn Mawr College
Andrew Moran (Ph.D. 2002)
Assistant Professor
Univ. of North Carolina, Chapel Hill
Nate Schultheiss (Ph. D. 2007)
Halliburton
(Fulbright Fellow with JeanMarie Lehn in 2008)
Gustavo Seabra (Ph.D. 2005)
Professor Adjunto
Universidade Federal de
Pernambuco, Brazil
Dr. Joaquin Urbina
Ph. D. 2005
Professor
University of Belize
Dr. Michelle Smith
Ph. D. 2009
GlaxoSmithKline, UK
Tom Everett (Ph. D. 2010)
Postdoc
Univ. of Missouri
QuickTime™ and a
decompressor
are needed to see this picture.
Safiyyah Forbes (Ph.D. 2010)
Assistant Professor
Monmouth College, Illinois
Dmytro Demydov (Ph. D. 2006)
Research Assistant Professor
Univ. of Arkansas
Johanna Haggstrom (Ph. D. 2007)
Halliburton in Lawton, OK
Dambar Hamal (Ph.D. 2009)
Postdoc
Univ. of Connecticut
Pubudu Gamage (Ph. D. 2009)
Postdoc
Univ. of Wyoming
Yen-Ting Kuo (Ph. D. 2010)
Postdoc
Univ. of Michigan
Jeff Lange (Ph. D. 2009)
Staff Scientist
Stowers Institute for Medical
Research in Kansas City
We also have a beautiful Campus..
Student Union
Anderson Hall
The Art Museum
The Farrel library
The Hale library
...with over 20,000 students.
KSU is located in Manhattan...
…in the Flint
Hills, NorthEast Kansas.
If you need more information about
Chemistry at Kansas State or if you
want to receive an application
package….
Contact:
Prof. Christer Aakeröy (aakeroy@ksu.edu)
or
Mary Dooley (mldooley@ksu.edu)
Welcome to Kansas State!
http://www.ksu.edu/chem/