MBI® Programme
2015-2016
Principles of Fermentation Processes
5-7 October 2015
Industrial Biotechnology: Biocatalysis
through to Synthetic Biology
18-20 April 2016
Rapid Fermentation Process Design: From
Development to Manufacture
26-28 October 2015
Analytical Data Analysis for the
Bioprocessing Industry
25-28 April 2016 (CPI, Darlington)
Downstream Processing – From Cell to
Column
16-19 November 2015
Stem Cell Training Course: Human
Pluripotent Stem Cells in Culture
25-27 April 2016
Downstream Processing –Chromatography
30 November-3 December 2015
Vaccines Bioprocess Development and
Commercialisation
17-19 May
Current Challenges in Mammalian Cell
Processing
25-27 January 2016
Bioprocess Design & Economic Evaluation
6-9 June 2016
Quality by Design for Effective Bioprocess
Characterisation and Validation
22-25 February 2016
Cell and Gene Therapy Manufacturing
1-3 March 2016 (Cell Therapy Catapult, London)
Design of Experiments for Bioprocess
Optimisation
7-9 March 2016
Bioprocess Facility Design
27-30 June 2016
Single Use Technology for Rapid
Manufacturing
11-13 July 2016
All courses held at the department of
Biochemical Engineering, University
College London unless otherwise
specified.
®
For up-to-date information on all MBI courses, visit
www.ucl.ac.uk/mbi
MBI Awards
®
2012 IChemE Award for Training Innovation
2014 UCL Life Learning Enterprise Award for CPD and Short Courses
Single-Use
Technologies for Rapid
Biomanufacturing
Discover new approaches to rapid scale translation
11-13 July 2016
Est. 1994
UCL
Single-Use Technologies for
Rapid Biomanufacturing
The module aims to deliver
new training material specific
to single-use technologies
encompassing different
process steps, scales of
operation and cell/product
systems. It will:
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• Consider the whole process
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•
•
•
•
and provide tools useful for the
evaluation and adoption of singleuse systems for a range of process
steps;
Build knowledge of engineering
fundamentals in single-use
systems and provide confidence in
scale translation and in the use of
these as scale-down models;
Focus on the different stages of
the development pathway, from
initial discovery and screening
studies to manufacturing;
Discuss adoption of these
technologies for different cell
systems and products (antibodyproducing mammalian cells used
as base case study, adherent cells
and high cell density organisms
among others);
Provide training on singleuse technologies specific
characteristics and requirements
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(sterile connections and
disconnections, standardization,
sensor technology, toxicologic
profiles and regulatory approval).
The course will be delivered as an
intense 3 days module, as part of
the already established MBI Training
Programme hosted by the Advanced
Centre for Biochemical Engineering
(ACBE) at UCL. A number of leading
vendors and industrialists in the
sector have been engaged to define
the course objectives, its content and
methods of delivery.
Who should attend?
The course is suitable for engineers,
biotechnologists and those with a life
science background who are or plan
to work with single-use technologies
for different processes and products.
In particular the module will suit
those responsible for the uptake
and selection of the technology, for
process development, technology
transfer and scale translation. Practical
sessions will help building confidence
in the use of the technology for
those planning to use it for the first
time. Delegates will also learn from
industrial experts experiences on the
challenges and opportunities around
single-use systems.
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Day 1
Fundamentals and
scale-up
• E
ngineering
fundamentals and
mixing in SUB
• Tech transfer and scale
translation
• Industrial speaker
presentation on scale up
case study
• SUB set-up, basic
operation and control
• S
ocial networking
dinner organised for
delegates and
speakers.
Module Leaders
Dr Martina Micheletti
UCL
Prof Gary Lye
UCL
Day 2
Technology evaluation
and selection
• Upstream
processing
• Primary recovery and
downstream processing
• SUT evaluation from
drug screening to
manufacturing: an
industrial perspective
• Sensor technology and
control software
Industrial Expert
Speakers Include
GE Healthcare
Sartorius Stedim
Pall
Applikon Biotechnologies
Merck Millipore
PM Group
For further information and bookings please contact:
E: mbi-training@ucl.ac.uk I Visit: www.ucl.ac.uk/mbi
T: +44 (0) 20 7679 9619 I +44 (0) 203 549 5619
Please note the agenda maybe subject to change.
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Day 3
Facility design and
validation
• SU-based
manufacturing platform:
ideas around the facility
of the future
• Validation and
regulatory approval
process for both
vendors and end-users
• Impact of SUT on the
reduction of carbon
footprint within a facility
• Aseptic connections
and disconnections,
standardization issues,
multiple operations
set-up