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FOR RELEASE OCT. L2
#roL29o-4
SCRIPPS CLINIC RECEIVES 91{ T,IIIJIJION
TO STUDY AIDS DEUENTIA
L2, 1990 --
LA JOLLA, CALfF. Oct.
Foundation
has
received
a
National
Institutes
Dementia
Complex Research
of
In announcing
executive
the
offj-cer
largest
single
Scripps
Clinic.
Floyd
grant
Bloom,
of
of
be the
central
only
M.D.,
Bloom
is
He added that
symptorns, but
inability
Scripps
grant
from
establish
biomedical
research
head of
Scripps
of
the
that
everyone
said,
president
Clinic
Edwards, M.D.,
in
with
said
the
an AIDS
and chief
that
it's
the
ever
to be awarded to
CLinic,s
Department
new center,
focuses
systern dernentia
dementia, rr
how it
C.
NIMH center
virtually
(NII[H) to
and Research
Center.
and director
nervous
Clinic
nillion
$r+
Health
funding,
for
I'Although
determine
Mental
Charles
Neuropharmacology
will
five-year
Scripps
GRANT
on the
noted
biologi-caI
a comprehensive
AIDS will
rrresearchers
have
that
of
this
basis
way.
express
been
some forrn
unable
to
have a variety
of
caused.rl
patients
generally
to do simple
with
AIDS dementia
complaj-n of
mathematic
lack
of
functions,
checkbooks.
MORE
concentration
and the
such as keeping
their
PAGE 2 --
GRANT FOR AIDS
rrSince the
HIV
virus
the virus
a
to
way
central
which
attack
survival
the
the
medications
HIV virus
role
participate
rrA Iot
necessary
for
may be
that
causingr
or
can depress
He
a well
the
in
tied
measurement
of
to
central
may be
some degree,
the
that
included
sensory
stages
the
in the disease,
system
infection
may
itself.
a healthy
system
the
nervous
system
infection
way in
is
which
is
rrlt
actuaJ-Iy
the
virus
irnmune systen. rl
studies
of
events
have
shown
in AfDS patients
that
brain
who thernselves
dementia.
computer
that
development
imrnune systemrrr Bloom said.
the
recent
the
systern early
changing,
of
in
on the way in which
nervous
nervous
any signs
sleep
focus
nervous
have been monitored
noticed
to
of AIDS.
wiII
functioning
that
These studies
activity
spread
believe
function
to
the
able
the brain
aid
immunodeficiency
central
added
yet
the
some fashion
the
abnormalities
had not
people
are infecting
may eventually
the
later
ttbeing
continued,
improve,
for
rl
research
which
the
of
and
the central
to
in
course
prevent
involves
and the
that
research
At the new center,
system may be a repository
cells
individual.
to
RESEARCH
AIDS, rr Bloom
in those
He added that
of
nervous
causes
prolong
of
DE}IENTIA
analysis
such
as
indicated
function.
UORE
of
brain
cricks
and
abnormalities
electrical
tones,
in
and
sleep
PAGE 3 --
GRANT FOR AIDS
rrlt may be that
decline
in
mental
general
way to
indicative
The
DE!,TENTIA RESEARCE
people
ability,
hearth
AfDS
decrine,
Dementia
within
the
Research Institute
investigators
of
Center
will
director,
define
the
of the brain,
infections,
neuronal
scientific
the
AIDS Dementia
light
like
will
be
may be
additional
based
at
the
collaborating
Departments
of
of Psychiatry
the
molecular
Cornplex. fn
and
of persistent
of
the
the
signals
effects
center
addition
incruding
BLoom
whose studies
virus
these
include
chemistry,
to
infections
activated
of
will
cellular
by these
signals
on
a number of
physiology,
anatomy
genetics.
Bloom noted that
of
Center
clinicrs
of celI-ceIl
Work at
disciplines,
it
some
San Diego.
actions
nature
in
that
wil-I be 23 co-investigators
biological
or
knowing
and the Department
investigate
there
fatigue
Neuropharmacology
with
AIDS Dementia
function.
and molecular
Biology,
the profiles
and
of
scripps
California,
will
to
Research
CIinic,
within
mechanisms underlying
as center
without
Department
based
that
some degree of
Bloom said.
of Scripps
University
The
but
Complex
Imrnunology and Molecular
the
AIDS are tolerating
attributing
of AIDS denentiarrr
prinarily
at
with
to their
Cornplex, studies
on the mental
schizophrenia.
ttin addition
disfunctions
at
that
rl
###
the
relevance
new center
occur
in people
to the nature
may also
with
shed
diseases