Product datasheet
Anti-CD49e antibody [CB49e], prediluted (PerCP)
ab106776
Overview
Product name
Anti-CD49e antibody [CB49e], prediluted (PerCP)
Description
Mouse monoclonal [CB49e] to CD49e, prediluted (PerCP)
Conjugation
PerCP. Ex: 482nm, Em: 675nm
Tested applications
Flow Cyt
Species reactivity
Reacts with: Human
Immunogen
The details of the immunogen for this antibody are not available.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 0.5% BSA, PBS, pH 7.4
Purity
Size exclusion
Clonality
Monoclonal
Clone number
CB49e
Isotype
IgG1
Applications
Our Abpromise guarantee covers the use of ab106776 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Flow Cyt
Abreviews
Notes
Use 10µl for 106 cells.
ab118658 - Mouse monoclonal IgG1, is suitable for use as an isotype control with
this antibody.
Target
1
Relevance
CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins
composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational
cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with
beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late
(activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular
matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell
surface mediated signalling.
Cellular localization
Type I membrane protein.
Form
Cleaved into the following 2 chains: 1) Integrin alpha-5 heavy chain 2) Integrin alpha-5 light chain.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Terms and conditions
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