Overview
Product name
Description
Tested applications
Species reactivity
Immunogen
Anti-alpha 1a Adrenergic Receptor antibody
Mouse monoclonal to alpha 1a Adrenergic Receptor
WB, ELISA
Reacts with: Human
Predicted to work with: Rabbit, Cow, Dog, Pig, Rhesus monkey
Recombinant fragment:
MVFLSGNASDSSNCTQPPAPVNISKAI
, corresponding to N terminal amino acids 1 - 27 of Human alpha 1c Adrenergic Receptor, with proprietary tag.
Run BLAST with Run BLAST with
HL60 cell lysate Positive control
Properties
Form
Storage instructions
Storage buffer
Purity
Clonality
Isotype
Light chain type
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: None
Constituents: PBS, pH 7.2
Protein A purified
Monoclonal
IgG1 kappa
Applications
Our Abpromise guarantee covers the use of ab87990 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application Abreviews Notes
WB
ELISA
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 51 kDa.
Use at an assay dependent dilution.
1

Target
Function
Tissue specificity
Sequence similarities
Post-translational modifications
Cellular localization
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and
G(11) proteins.
Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary.
Within the prostate, expressed in the apex, base, periurethra and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily.
Carboxyl-terminal Ser or Thr residues may be phosphorylated.
Cell membrane.
Anti-alpha 1a Adrenergic Receptor antibody images
Anti-alpha 1a Adrenergic Receptor antibody
(ab87990) at 1 µg/ml + immunogen (tagged recombinant fragment) at 0.2 µg
Secondary
Goat anti-Mouse IgG at 1/10000 dilution
Predicted band size : 51 kDa
Western blot - alpha 1c Adrenergic Receptor antibody (ab87990)
Anti-alpha 1a Adrenergic Receptor antibody
(ab87990) at 1 µg/ml + HL60 at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/10000 dilution
Predicted band size : 51 kDa
Western blot - alpha 1c Adrenergic Receptor antibody (ab87990)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Our Abpromise to you: Quality guaranteed and expert technical support
Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
2

Response to your inquiry within 24 hours
We provide support in Chinese, English, French, German, Japanese and Spanish
Extensive multi-media technical resources to help you
We investigate all quality concerns to ensure our products perform to the highest standards
If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team.
Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
3