Product datasheet
Anti-Butyrylcholinesterase antibody [EPR3033(2)]
ab151554
1 Image
Overview
Product name
Anti-Butyrylcholinesterase antibody [EPR3033(2)]
Description
Rabbit monoclonal [EPR3033(2)] to Butyrylcholinesterase
Tested applications
WB
Species reactivity
Reacts with: Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (C
terminal)
Positive control
A375, HeLa and 293T cell lysates.
General notes
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the
following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with
these species. Please contact us for more information.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at -20ºC.
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purity
Tissue culture supernatant
Clonality
Monoclonal
Clone number
EPR3033(2)
Isotype
IgG
Applications
Our Abpromise guarantee covers the use of ab151554 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
Abreviews
WB
Application notes
Notes
1/1000 - 1/10000. Predicted molecular weight: 68 kDa.
Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Target
Function
Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter
acetylcholine. Can degrade neurotoxic organophosphate esters.
Tissue specificity
Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
Involvement in disease
Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency)
[MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea
after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or
mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies
significantly depending on the extent of the enzyme deficiency. BChE deficiency is a
multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.
Sequence similarities
Belongs to the type-B carboxylesterase/lipase family.
Cellular localization
Secreted.
Anti-Butyrylcholinesterase antibody [EPR3033(2)] images
All lanes : Anti-Butyrylcholinesterase
antibody [EPR3033(2)] (ab151554) at 1/1000
dilution
Lane 1 : A375 cell lysate
Lane 2 : HeLa cell lysate
Lane 3 : 293T cell lysate
Lysates/proteins at 10 µg per lane.
Secondary
Western blot - Anti-Butyrylcholinesterase
HRP labeled goat anti-rabbit at 1/2000
antibody [EPR3033(2)] (ab151554)
dilution
Predicted band size : 68 kDa
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Replacement or refund for products not performing as stated on the datasheet
Valid for 12 months from date of delivery
Response to your inquiry within 24 hours
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We investigate all quality concerns to ensure our products perform to the highest standards
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Terms and conditions
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