Curriculum vitae
Arnob Dutta
Name:
Arnob Dutta
Current Address:
4901 Wornall Road, Apt 306, Kansas City, MO 64112, USA
Daytime phone no:
1-814-574-6523
Email address:
aod@stowers.org, duttaaarnob@gmail.com
Current position:
Post-doctoral associate at the Stowers Institute for Medical Research
Educational and professional qualifications
2011- present
Post-doctoral researcher
Stowers Institute for Medical Research, Kansas
City, MO, USA
Mentor: Dr. Jerry L. Workman
2004-2010
Ph.D. in Cell and
Developmental Biology,
Integrative Biosciences
Pennsylvania State University, State College,
PA, USA
Title of thesis: Understanding how Dhh1 and Ccr4-Not regulate mRNA metabolism in yeast.
Thesis advisor: Dr. Joseph Reese
2001-2004
M. S. in Biology
Tata Institute of Fundamental Research,
Mumbai, India
Title of thesis: Molecular aspects of genetic repair
Thesis advisor: Dr. BJ Rao
1998-2001
B.Sc. in Microbiology and
Biotechnology
Ramnarain Ruia College, Mumbai University,
Mumbai, India
Publications
1. Dutta A and Workman JL. In vitro assembly of nucleosomes for binding/remodeling assays. (2015)
Methods in Molecular Biology. (in press)
2. Dutta A, Babbarwal V, Fu J, Brunke-Reese D, Libert DM, Willis J, Reese JC. Ccr4-Not and TFIIS
function cooperatively to rescue arrested RNA polymerase II. (2015) Mol Cell Biol. 35(11): 1915-25
3. Huang F, Paulson A, Dutta A, Venkatesh S., Smolle M., Abmayr SM, and Workman JL. Histone
Acetyltransferase Enok Regulates Oocyte Polarization by Promoting Expression of the Actin
Nucleation Factor spire. (2014) Genes and Development. 28(24): 2750-63
Curriculum vitae
Arnob Dutta
4. Dutta A, Gogol M, Kim JH, Smolle M, Venkatesh S, Gilmore J, Florens L, Washburn MP and
Workman JL. Swi/Snf dynamics on stress responsive genes is governed by competitive
bromodomain interactions. (2014) Genes and Development. 28(20): 2314-30
5. Hepp MI, Alarcon V, Dutta A, Workman JL and Gutiérrez JL. Nucleosome remodeling by the
SWI/SNF complex is enhanced by yeast High Mobility Group Box (HMGB) proteins. (2014)
Biochim Biophys Acta. 1839(9): 764-72
6. Dutta A and Workman JL. Remodeling without a power stroke. (2013) EMBO Rep. 14(12): 1030-1
7. Dutta A and Workman JL. Nucleosome positioning: multiple mechanisms towards a unifying goal.
(2012) Molecular Cell. 48: 1-2.
8. Kruk J*, Dutta A*, Fu J, Gilmour DS and Reese JC. The multifunctional Ccr4-Not complex directly
promotes transcription elongation. (2011) Genes Dev. 25(6): 581-93. (Equal contribution)
9. Dutta A, Zheng S, Jain D, Cameron CE and Reese JC. Intermolecular interactions within the
abundant dead-box protein Dhh1 regulate its activity in vivo. (2011) Journal of Biological
Chemistry. 286(31): 27454-70
10. Navadgi V, Dutta A and Rao BJ. Human Rad52 facilitates a Three-strand pairing that follows no
strand exchange: A Novel Pairing function of the Protein. (2003) Biochemistry. 42: 15237-51.
11. Dutta A, Rao BJ and Chary KV. Overexpression and purification of isotopically labeled Escherichia
coli MutH for NMR studies. (2003) Protein Expr Purif. 29: 252-8.
Awards & Scholarships
1. ASBMB travel award to attend ASBMB annual meeting in Anaheim, CA (2010)
2. Huck Institute of Life Sciences fellowship, Pennsylvania State University, PA (2004-2005)
3. Awarded the Vidya Bhushan Award (Best student award) at Ramnarain Ruia College, Mumbai
(2000-2001)
4. Award for highest in subject (Microbiology) at Ramnarain Ruia College, Mumbai (2001)
5. Summer Fellowship by Jawaharlal Nehru Centre for Advanced Scientific Research for Summer
Project at National Center for Biological Sciences, Bangalore (April-June, 2000)
Invited talks
1. Indian Institute of Science Education and Research, Bhopal, India. February 6th, 2015
Title of talk – “Multiple mechanisms to regulate the Swi/Snf chromatin remodeler.”
2. Jawaharlal Nehru University, New Delhi, India. February 2nd, 2015
Title of talk – “Regulating chromatin remodeler function by multiple mechanisms.”
3. Tata Institute of Fundamental Research, Mumbai, India. January 23rd, 2015
Title of talk – “Dynamics of Swi/Snf chromatin remodeler function is regulated by competitive
bromodomain interactions”
4. Ramnarain Ruia College, Mumbai University, Mumbai, India. January 21th, 2015
Title of talk – “Regulation of transcription by chromatin remodelers.”
Seminars and Conferences
Curriculum vitae
Arnob Dutta
1. Gene networks in chromatin/chromosome function, 5th Meeting of the Asian Forum of
Chromosome and Chromatin Biology, January 15th-18th, 2015, JNCASR, Bangalore. Title of poster Swi/Snf dynamics on stress responsive genes is governed by competitive bromodomain interactions.
“Awarded best poster at the meeting”
2. ASBMB Special Symposium, Transcriptional Regulation: Chromatin and RNA Polymerase II,
October 2nd-6th, 2014, Snowbird, Utah. Title of poster - Swi/Snf dynamics on stress responsive genes is
governed by competitive bromodomain interactions.
3. Keystone symposium on Eukaryotic transcription, March 31st-April 5th, 2012, Snowbird, Utah. Title
of poster - Acetylation of Snf2 by Gcn5 regulates Swi/Snf function.
4. ASBMB Annual meeting, April 24th-28th, 2010, Anaheim, CA. Title of poster - Roles of the yeast
Ccr4-Not complex in regulating transcription.
5. CSHL conference on Mechanisms of Eukaryotic Transcription. August 25th-29th, 2009. Cold Spring
Harbor Laboratory, Cold Spring Harbor, NY. Title of poster- A structure function analysis of Dhh1, a
DEAD box helicase involved in stress induced regulation of RNA.
6. MSU summer symposium on Transcription Regulation and System Biology, July 18th -20th, 2008,
Michigan State University, Lansing, MI. Title of poster - Characterization of Dhh1, a DEAD box
helicase involved in stress response.
“Awarded best poster at the meeting”.
7. 26th Summer Symposium “Chromatin and Epigenetic Regulation of Transcription”, at Pennsylvania
State University, PA. June 19th -22nd, 2007
8. Special symposium on recent developments in NMR Methodology & National symposium on
Magnetic Resonance, February 3rd-6th, 2003, Indian Institute of Science, Bangalore, India. Title of
poster- Towards understanding MutH endonuclease action on duplex-DNA containing a hemimethylated
–GATC- tract: Preliminary NMR characterization.
9. 28th Mahabaleshwar seminar in Modern Biology 2002, “Cellular Traffic”, February 23rd-March
2nd, 2003, Tata Institute of Fundamental Research, Mumbai, India.