Focus for the Future, September 2015
Building on the strengths of UCL’s cohorts
Cardiometabolic Phenotyping group
What do we do now?
Structure and function of the cardiovascular system
in health and disease.
Aetiology, mechanisms, prevention of disease.
Imaging, computational methods  application in
large clinical trials and epidemiological studies.
Particular focus on ethnic minorities both in UK
(SABRE study) and overseas.
Building on the strengths of UCL’s cohorts
• Defining critical periods/ indicators during lifecourse for optimal interventions
• Updating traditional measures for population
research
• Imaging can detect subclinical disease and risk
progression, e.g.
– DXA –bones and fat
– MRI- brain, cognition
– 3D ultrasound - heart and vascular function
• Home devices for long-term monitoring
• Interventions
• Training and teaching
Collaborations
• UCL Cohorts: SABRE, Whitehall II(planning),
NSHD(1946)(in process), ELSA, NCDS(1958),
British Cohort Study (1970)
• UCLEB (UCL-Edinburgh-Bristol) consortium
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CMIC (Centre for Medical Imaging Computing)
Brain Sciences
Institute for Digital Health
Wellcome Centre for Ageing and Polymorbidity
Research (proposed)
• Centre for Behavioural Change
• MRC Clinical Trials Unit
Cardiometabolic
Phenotyping Group
Prof. Nish Chaturvedi
Prof. Alun Hughes
Emma Coady
Sophie Eastwood
Charlotte Manisty
Chloe Park
Therese Tillin
Emily Williams
Eddi Chibundu Campbell
Hassina Furreed
Innocent Bvekerwa
Daniel Key
Siana Jones
Katherine March
April McGowan
Sabby Mondair
Hakim-Dehbi Moulay
Rose Mullett
Alicja Rapala
Lorna Smith
Suzanne Williams