LabNotes Coming in July Biosafety Information Online (BIO)

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LabNotes

SAFETY NEWS FOR UC SAN DIEGO RESEARCHERS

Env iro nm e nt , H ealth & S af e t y N o. 95 Sp r in g 2012

Sanford Consortium Shuttle

Shuttle service from the Sanford Consortium building to campus operates weekdays, 8 a.m. – 5 p.m., except university holidays.

See the schedule at http://blink.ucsd.edu/ facilities/transportation/shuttles/sanford.html

Coming in July

Biosafety Information Online (BIO)

UC San Diego researchers will be the first among UC campuses to use the new systemwide Biosafety Information Online (BIO) application for biohazard use authorizations.

BIO was modeled on and will replace UCSD’s current online Biohazard

Use Authorization (BUA) application. When BIO launches in July, current

BUA information will be transferred into the new BIO application. UCSD researchers will have the advantage of a familiar application provisioned with new features including sections for Risk Assessment, NIH

Recombinant DNA Guidelines, and Dual Use, as well as expanded plant information and much more.

Questions? Contact EH&S Biosafety: (858) 534-5366 or ehsbio@ucsd.edu.

Chemical Hazard Use Application (CHUA)

New Online Tool Coming Soon to a Lab Near You!

The new online Chemical Hazard Use Application (CHUA) is part of a campuswide program to provide researchers with a vetted, documented method for effectively and predictably educating and training employees to safely handle high hazard materials.

How the CHUA program will work

Thirty chemical agents are currently approved by UCSD’s Chemical Safety & Surveillance

Committee (CSSC)* for inclusion on the high hazard list. Using the campus chemical inventory, listed high hazard chemicals will be identified, located, and tagged with a warning that any use requires approval through the CHUA process.

Hazard Control Plans (HCPs) for high hazard chemicals are drafted by the campus Chemical

Hygiene Officer in collaboration with other technical experts, and reviewed and approved by the CSSC. Investigators working with high hazard chemicals will use CHUA to obtain an approved HCP and ensure lab staff receive safety training and follow procedures prescribed by the HCP.

Environment, Health & Safety will begin introducing the CHUA program to campus labo-

ratories in the very near future. Contact Chemical Hygiene Officer Doug Harvey at (858)

583-3257 or daharvey@ucsd.edu, if you have questions about CHUA.

*The CSSC advises the Chancellor on the safe use of hazardous chemicals, reducing risks associated with hazardous chemicals, and establishing and implementing policies and procedures for chemical safety at UC San Diego.

Get Help with the

Online BUA

Baffled by your lab’s online Biohazard Use Authorization (BUA)?

Learn more about the process as Associate

Biosafety Officer Carol

Kent explains what a

BUA is and walks you through the BUA Web application in a video presentation (33:51 min) online at: http://blink.ucsd.edu/technology/ media/podcasts/blinkcast/SPEC/ biohazard.html

If you’re new to UCSD, have problems accessing your BUA or finding your way around in the BUA application, this video can help.

Questions? Contact EH&S Biosafety at ehsbio@ucsd.edu.

Shipping Hazardous Materials

Corridors: Pathways to Safety

Conditional BSL Containment for Adeno-Associated Virus

University of California, San Diego-Environment, Health & Safety

)

(858) 534-1954

-

0920

:

ehsweb@ucsd.edu

:

http://blink.ucsd.edu/ehs

Clutter-Free Corridors

Are Pathways to Safety

You need a clear way out of your building during an evacuation.

Cluttered corridors obstruct evacuation when every second counts.

UCSD’s corridor safety requirements aim to ensure building occupants have a clear pathway and safe exit in an emergency.

Never store or use hazardous materials in a corridor.

In general, nothing may obstruct the required minimum width of a corridor. Only equipment or material authorized and tagged by Environment, Health & Safety may be placed in a corridor.

Fire safety requirements in healthcare settings are more restrictive than nonpatient care environments. No items may be stored in hospital or clinic corridors.

Learn what is permitted and prohibited in UCSD corridors. See “Corridor

Safety Requirements” on Blink at http://blink.ucsd.edu/go/corridor/ .

Biosafety Containment:

Adeno-Associated Virus

Adeno-associated virus and AAV vectors may be handled at Biosafety

Level 1 (BSL-1) and Animal Biosafety Level 1 (ABSL-1) when they are:

Made in the absence of helper virus (such as Adenovirus and Herpes virus)

Used in the absence of any Risk Group 2 material

Free of any hazardous transgenes (such as an oncogene, toxin, shRNA from tumor suppressors, etc.)

These conditions apply:

1.

2.

3.

4.

Do not manipulate AAV in a biosafety cabinet at the same time as

Risk Group 2 materials.

Decontaminate work areas before and after use.

If experiments with AAV also include Risk Group 2 materials or hazardous transgenes, BSL-2 and ABSL-2 containment rules apply.

Work in animals:

For previously approved projects using AAV, a meeting with the Vivarium Safety Officer, (858) 534-6715, is required prior to changing existing animal housing requirements.

For new projects using AAV, list AAV as a hazard in section 8 of the animal use protocol.

Questions?

Contact EH&S Biosafety at ehsbiosafety@ucsd.edu.

ChemCycle

UCSD’s chemical recycling facility

Good for the pocketbook and the environment.

http://www-ehs.ucsd.edu/chemcycle/

Shipping

Hazardous

Materials

What You

Need to Know

UC San Diego conforms to strict government regulations when transporting hazardous materials. All outgoing shipments of any infectious substance, diagnostic specimen, or other hazardous material must:

• Be processed by a certified UCSD Shipping Department employee

Arrive at the destination in good condition

Present no hazard during shipment

Warning: Failure to comply with international and federal transportation regulations when shipping hazardous materials can result in civil penalties of

$50,000 per occurrence, and criminal penalties may include 5 years of imprisonment in addition (49CFR

107.329-107.333).

When you need to ship or transfer hazardous materials*

Don’t move the shipment yourself. Contact Shipping in advance and follow the guidelines at http://blink.

ucsd.edu/go/shiphazmat .

Shipping prepares all hazardous materials transport documents prior to the pick-up or movement of hazardous materials. This ensures UCSD is in compliance to move the item across public roads to the Shipping

Office on Trade Street.

Give Shipping advance warning if your shipment contains multiple hazardous materials. Completing required paperwork for such shipments can take several days.

*Radioactive materials exception

If you plan to ship radioactive materials, follow instructions on “How to Transfer Radioactive Materials” at http://blink.ucsd.edu/safety/research-lab/radiation/ transfer.html

.

Training requirement to ship biological substances and dry ice

Training and certification is required for departments to ship biological substances and dry ice. Training participants must pass a test to receive certification to ship biological substances and dry ice. Recertification is required every 2 years.

Contact BFS Shipping for training schedules: bfsshipping@ucsd.edu or (858) 536-3225, Ext. 244

University of California, San Diego-Environment, Health & Safety

)

(858) 534-1954

-

0920

:

ehsweb@ucsd.edu

:

http://blink.ucsd.edu/ehs

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