ULMSchoolofPharmacy Spring2016
BoneandJointModule:PHRD5027(CRN62141)
I.ContactInformation
CourseCoordinators:
Dr.JamieTerrell,Pharm.D.
AssociateProfessor
Claiborne114(Shreveport)
Phone:318-632-2007
*Email:terrell@ulm.edu
Officehours:T–F9:00to11:00am,Th1:00to3:00pmorbyappointment
Dr.AlexisHorace,Pharm.D.
AssistantProfessor
3849NorthBlvd:202(BatonRouge)
Phone:225-219-9660
*Email:horace@ulm.edu
Officehours:MandW1:00to4:00pm,andF8:00to11:00am
Instructors:
Dr.JessicaBrady,Pharm.D.,BCPS
AssociateProfessor
BienvilleBuilding115
Phone:318-342-1697
*Email:brady@ulm.edu
Officehours:MthruTh1:00to4:00pm
Dr.MichaelCockerham,MS,Pharm.D.,FASHP
AssociateDeanforAcademicAffairsandProfessor
BienvilleBuilding-Dean’sSuite
Phone:318-342-3171
*Email:cockerham@ulm.edu
Officehours:MandTh9:00amto3:00pmorbyappointment
Dr.RonaldHill,Ph.D.
AssociateProfessorofMedicinalChemistry
BienvilleBuilding310
Phone:318-342-1706
Email:rhill@ulm.edu
Officehours:M12:00to1:00pm,5:00to6:00pm;T9:30to10:00am,11:00
to12:00pm,5:00to6:00pm;W12:00to12:30pm,4:00to5:30pm;Th9:30
to10:00am,11:00to12:00pm,5:00to6:00pm;F12:00to1:00pm
Dr.StephenHill
AssistantProfessor
BienvilleBuilding
(318)342-1730
*shill@ulm.edu
Officehours:Mon-Thurs1-4
Dr.AlexisHorace,Pharm.D.
AssistantProfessor
3849NorthBlvd:202(BatonRouge)
Phone:225-219-9660
*Email:horace@ulm.edu
Officehours:MandW1:00to4:00pm,andF8:00to11:00am
Dr.SeetharamaD.S.Jois,Ph.D.
AssociateProfessorofMedicinalChemistry
BienvilleBuilding316
Phone:318-342-1993
*Email:jois@ulm.edu
*Officehours:MthruTh10:00amto1:00pmorbyappointment
II.
Dr.SavannahPosey,Pharm.D.
AssistantProfessor
BienvilleBuilding123
Phone:318-342-3176
*Email:posey@ulm.edu
Officehours:MthruTh8:00amto11:00am AmandaStorer,Pharm.D.
ClaiborneBldg.,Office111
ShreveportCampus
(318)632-2007
*storer@ulm.edu
Officehours:M-F2:00-3:00PM
Dr.PaulSylvester,Ph.D.
PfizerEndowedProfessorofPharmacology
BienvilleBuilding344
Phone:318-342-1958
*Email:sylvester@ulm.edu
Officehours:MthruTh11:00amto1:00pm;F8:00to10:00am
*Denotespreferredmethodofcontact
III.
IV.
CoursePrerequisites
PHRD4058,PHRD4074
Co-requisite:PHRD5033
CourseDescription
2Cr.Principlesofpathophysiology,pharmacology,medicinalchemistry,clinicalpharmacokineticsand
pharmacotherapy(includingbothprescriptionandnonprescriptionmedications)astheyapplytoboneand
jointdiseasedrugtherapymanagement.
CurricularObjectivesandOutcomes(selectedfromatotalof34)
a.
ProvideComprehensivePatientSpecificPharmaceuticalCare
1. Evaluatetheappropriatenessofagivenprescriptionormedicationorderbasedonpatientand
disease-specificfactors.
3. Developandimplementanevidence-basedcareplan.
5. Documentallactivitiesinvolvedwiththeprovisionofcomprehensivepatientspecific
pharmaceuticalcare.
b.
CommunicateEffectively
6.
8.
Counselandeducatepatientsregardingmedicationuse,diseasestatemanagementandhealth
maintenance.
Collaboratewithotherhealthcareprofessionalsusingappropriateeffectivecommunicationinboth
writtenandoralforms.
c.
ThinkCritically
24. Identify,retrieve,understand,analyze,synthesize,andevaluateinformationneededtomake
informed,rational,andethicaldecisions.
25. Solvecomplexproblemsthatrequireanintegrationofone’sideasandvalueswithinacontextof
scientific,social,cultural,legal,clinical,andethicalissues.
26. Displayhabits,attitudes,andvaluesassociatedwithmaturecriticalthinking.
d.
29.
31.
33.
34.
V.
VI.
VII.
DemonstrateAppropriateInterpersonal,Professional,andEthicalBehaviors.
Identify,analyze,andresolveethicalproblemsinvolvedinpharmacypractice.
Collaborateproactivelywithotherhealthcareprofessionals.
Accepttheresponsibilitiesembodiedintheprinciplesofpharmaceuticalcare.
Demonstrateappropriateinterpersonal,intergroup,andcross-culturalbehaviorsthatpromote
respectandtrustfrompeers,patients,andcommunitymembers.
CourseSpecificObjectivesandOutcomes
Attheconclusionofthiscourse,studentsshouldbeableto:
a.
Demonstrate knowledge of the medicinal chemistry, pharmacological mechanism of action and
relatedpharmaceuticaltopicsofselectedmedicationsandmedicationclassesusedtotreatboneand
jointdisorders.
b.
Identify appropriate nonpharmacologic therapy, based upon patient- and disease-specific
information.(1,3,5,24,25,26,29,31,33,34)
c.
Develop appropriate pharmacotherapeutic regimens based upon patient- and disease-specific
information.(1,3,5,8,24,25,26,29,31,33,34)
d.
Developaplanformonitoringthepharmacotherapeuticregimenforefficacy,toxicity,andadverse
effects.(1,3,5,8,24,25,26,29,31,33,34)
e.
Developaplanforeducatingthepatientregardingdrugtherapy.(1,3,5,6,24,25,26,29,31,33,34)
f.
Reviewapatient-specificdrugtherapyregimenandmakeadjustmentsasnecessary.(1,3,5,8,24,
25,26,29,31,33,34)
CourseTopics
Physiology, pharmacology and medicinal chemistry related to selected bone, joint, and muscle disorders,
rheumatoidarthritis,osteoarthritis,osteoporosis,gout,systemiclupuserythematosus,andmyalgias.
InstructionalMethodsandActivities
Instructional methods may include: traditional lectures, distance learning, in-class discussion of patient
cases, small group discussions, problem-based learning, case-based learning, and individual projects or
assignments.
VIII. EvaluationandGradeAssignment
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Therewillbe2exams(withpointsdeterminedbynumberoflectures)andafinalexam(withpoints
determinedbynumberoflectures).Thefinalexamwillbenon-comprehensive.
Quizzes/assignmentswillbegivenasdeemednecessarybyeachfacultymember.
ExamdatesarescheduledinthecoursesyllabusandwillonlybechangedintheeventofUniversity
closure.
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ExamsmaybegivenusingExamSoft,andmayincludemultiplechoice,fillintheblank,short-answer,
case- or scenario-based discussion, essay, or any other question format deemed necessary by the
lecturersandcoursecoordinators.
o ExamSoftexams
§ Theexamwillbemadeavailableinatimesuchthatstudentswillbeableto
downloadtheexamPRIORtothetesttime.Studentswillnotbegivenextra
timetotaketheexamtoallowforthedownloadingofthetestdocument.
§ Studentswillbegiven1blanksheetofscratchpaperonwhichtheywill
writetheirnameandCWIDonthetoptobeturnedinimmediatelyafterthe
exam.
§ Scoreswillbemadeavailableimmediatelyattheclosingoftheexam.
§ Studentsmustuploadtheexaminatimelyfashion.Failuretodosowill
resultinazeroonthatexam.Intheeventofaninternetissue,studentswho
haveanissueuploadingtheexamwillcontactthecoursecoordinators
immediatelyanditwillbeaddressedatthediscretionofthecoordinators.
§ StudentswillNOTbeallowedtoleavetheclassroomwiththeircomputer
PRIORtotheendoftheexaminationperiod.
§ Students wishing to review their exam will make an appointment with the course
coordinators(ortheirproxy)todoso.
Normallaboratoryvalueswillbeprovidedforallquestions,unlessotherwisespecifiedduringclass.
Labvaluesthatarespecifictoaparticulardiseasestatewillnotbeprovided.
Informationacquiredfrompreviouslecturesinthecourseandfromothercoursesintheprofessional
pharmacycurriculummaybeneededinpreparingfortheseexaminations.
Examswillcovermaterial(readings,outsideassignments)notcoveredinclass.
Acceptableexambehavior
o Onlyawritinginstrumentshouldbeatyourdesk.Allbookbagsandotherbagsshouldbeleft
atthefrontoftheroom.
o Cellphonesshouldbeturnedoffandleftwithyourbelongingsinthefrontoftheroom.
o Studentswillnotbeallowedtoleavetheroomtogototherestroomduringtheexam,unless
accompanied by a faculty member of the same sex, provided there is another proctor to
remainintheroom.
o ForexamsgivenusingExamSoft,computersusedfortheexammustremainintheclassroom
untiltheclassperiodisover.
Useofprogrammablecalculatorswillnotbeallowedduringquizzesorexams.
Intheeventthataquestioniseliminatedfromanexamafterithasbeenprinted/downloaded,
the exam will be graded based on the remaining number of questions and adjusted to
representthecorrectnumberofpoints.
o Forexample,ona100-pointexam,ifone2-pointquestioniseliminated,theexamwillnowbe
worth98points,not100points.Nocreditwillbegivenfortheeliminatedquestion.
Studentswishingtochallengeaquestiononthetestmustprovidethecoursecoordinatorswitha
written(emailpreferred)statementthatidentifieswhichquestion(s)is/arebeingchallenged,why
thestudentfeelshisorheranswer(s)is/arecorrect,andreferencesfromrecent(publishedwithin
the last 1-2 years) primary or tertiary literature to support the claim. Problems or issues with
question(s)shouldbefirstdirected,viae-mail,tothefacultymemberwhopresentedthematerial.
The course coordinators should be copied on this communication. In the event that the faculty
memberandthestudentcannotarriveatanacceptableconclusion,thecoursecoordinatorsshould
be contacted regarding the issue. Discussion of a dispute will occur only after a written query is
submitted.Challengesoftestquestionswillonlybeconsideredwithin2weeksofwhenthetestscores
areposted.
Individualtestgradesforthecoursewillbebasedstrictlyuponthesepercentages.Therewillbeno
curvingoradjustmentsofgradesexceptinthecaseofanincorrectquestion.
Undergraduate mid-term grades will be posted on-line for students to view via Banner. Mid-term
gradesindicateastudent’sstatusatmid-semesteronlyanddonotindicatethefinalperformance
outcomeofastudent.
Assessmentmethod Examinations
Exam#1(lectures1-9)
Exam#2(lectures10-16)
Final(lectures17-24)
Assignments/quizzes
Points
90
70
80
TBD
GradingScale:
90–100%
A
80–89.5%
B
70–79.5%
C
60–69.5%
D
<59.5%
F
StudentSuccessPolicy:http://www.ulm.edu/pharmacy/documents/ospa/earlyintervention.pdf
“Studentsscoring<70%(excludesquizzes,assignments,bonus,etc.)willberequiredtosubmittothe
coordinatorwritten,narrativeresponsestoselectlectureobjectivesthatwillbeprovidedwithin24hours
ofthepostingoftheirexamgradetoMoodle.TheseobjectiveswillbeintheformofaMoodleassignment
andrepresentunit-orlecture-levelobjectivestobetesteduponinthenextscheduledcourseexam.
Writtenresponsesmustbesubmittednolaterthanonecalendarweekbeforethenextscheduledexam.
Responsesmustbewrittenincompletesentencesandmaynotbecopiedorpastedfromanysource,
includingclassnotes,treatmentguidelines,textbooks,oranyinternetsite.Submissionsfoundtocontain
responsesthathavenotbeenwritteninastudent’sownwordswillbeconsideredafailuretosubmit.
Inaddition,studentswillberequiredtorevieweachfailedexam’sExamSoft-generatedmisseditemreport
withtheinstructorresponsibleforeachsectionofmaterial.Thediscussionshouldincludethestudent’s
reasoningfortheincorrectansweraswellasthereasonforthecorrectanswer.
Inadditiontoansweringobjectivesasdescribedaboveandreviewingmisseditemreports,first
professionalyearstudentsscoring<70%onanyexamandhavinganoverallexamaverage<70%(excludes
quizzes,assignments,bonus,etc.)willmeetwiththeDirectorofProfessionalAffairs.
Failuretosubmitthisrequiredassignmentwillresultinineligibilitytoremediate.”
RemediationPolicy:http://www.ulm.edu/pharmacy/documents/ospa/remediationpolicy.pdf
Remediationisaprivilegethatmustbeearnedthroughdemonstratedattendanceandactiveparticipation
throughoutthesemesterthatthenon-progressinggradewasearned.Tobeeligibleforremediation,the
studentmusthavedemonstratedregularattendance,completedallassignedworkinthecourseand
utilizedotheracademicresourcessuchastutoringandmeetingswiththeinstructor.
Remediationwillbeofferedtoanystudentearningacourseaverageof≥65%regardlessofthetotal
numberofstudentsfailing.If≥7%oftheenrolledstudentsfailtoearnagradeof“C”orbetterinarequired
course,thenremediationwillbeallowedforanystudentearningafinalnonprogressinggradeof“D”or“F”
forthecourse.Thosewhochooseremediationwillbegivenanincomplete(“I”)untilthetimethat
remediationisfinished.
Studentschoosingremediationmustmakeascoreof≥70%onthetargetedremediationexamtopassand
receiveafinalgradeof“C”inthecourse.Nogradehigherthana“C”canbemadeinthecoursewith
remediation.Ifthestudentmakesagradeof<70%onthetargetedfinal,theiroriginalgradewilltakethe
placeofthe“I”grade.Thestudentcanthenre-enrollinthecourseatthenextofferingifeligiblebased
basedonschoolprogressionpolicies.Ifthisisthestudent’ssecond“F”gradeinthecurriculum,thestudent
willbedismissedfromtheprogram.
Studentswillbeallowedtoremediatewithatargetedremediationexamnomorethanthree(3)timestotal
intheirP1-P3years.Studentsmaynotremediateaclassmorethanonce.Therewillbenomake-upexams
intheremediation.
Studentswithagradeof“C”orbetterarenoteligibletouseremediationinanattempttoimprovetheir
gradeinthatcourse.
Studentsreceivinganon-progressinggradeasaresultofadisciplinaryactionarenoteligibletoremediate
thatcourseinthatsemester.
IX.
ClassPoliciesandProcedures
At a minimum, all policies stated in the current ULM Student Policy Manual & Organizational
Handbook should be followed (see http://www.ulm.edu/studentpolicy/). Additional class policies
include:
a.
1.
2.
3.
4.
Textbooks(required):
Chisholm-Burns M, Schwinghammer TL, Wells BG, Malone PM, Kolesar JM, DiPiro JT, eds.
Pharmacotherapy: Principles and Practice. 2nd ed, New York, McGraw-Hill, Inc., 2010. ISBN
9780071621809
Brunton LL, Lazo JS, Parker KL, eds. Goodman and Gilman’s, The Pharmacological Basis of
Therapeutics, 11th ed, McGraw-Hill, 2006. ISBN 9780071422802 (available through
AccessPharmacy)
Lemke, Williams, Roche, Zito, eds. Foyes Principles of Medicinal Chemistry 7th ed., Walters
Kluwer/LippincottWillams&Wilkins,2013.ISBN978-1-60913-345-0.(Thistextisavailableviaour
LW&WHealthLibrarycollection.)
AdditionalREQUIREDreadingmaterialsmaybepostedonMoodlebycoursefaculty.
b.
AttendancePolicy:Classattendanceisregardedasanobligationaswellasaprivilege,andstudents
are expected to know attendance regulations and to attend regularly and punctually at classes in
whichtheyareenrolled.Failuretodosomay:(1)preventaccesstotheclassroomduringregularly
scheduledtimes;(2)jeopardizeastudent’sscholasticstanding;and(3)leadtosuspensionfromthe
SchoolorUniversity.Studentsmustsubmitexcusesforclassabsencestocoursecoordinatorswithin
threeclassdaysafterreturningtoclasses.
ProfessorsshallacceptanofficialUniversityexcuse.Withthefollowingexceptions,professorsareto
determinewhetherabsencesareexcusedorunexcused:1)Absencesarisingfromauthorizedtrips
away from the University or from special duties at the University shall be excused. 2) Absences
arising from a student’s confinement in a hospital or other in-patient facility or doctor’s excused
absencesshallbeexcused.Studentsareresponsibleforverifyingprovidingdocumentationtothe
faculty, which will be verified. 3) Absences arising from a death in the immediate family shall be
excused.Theimmediatefamilyisdefinedasspouse,child,step-child,mother,father,sister,brother,
grandmother,grandfather,step-mother,step-father,step-brother,step-sister,aunt,uncle,motherin-laworfather-in-law.
c.
Make-upPolicy:Eachstudentisexpectedtoattendeachexamatthedateandtimespecified.Ifa
studentcannotattendanexamduetovalidUniversityexcuse,he/shemustspeakdirectlywiththe
course coordinator, as soon as possible. The course coordinator must be notified prior to an
examinationifastudentmissesanexam.TheULMCOPExcusedAbsencePolicymustbefollowed.
Pleaserefertotheofficialdocumentfordetails.Incaseofemergency,thecoursecoordinatormust
benotifiedwithin48hoursoftheemergency.Failuretodosowillresultinazero(0)gradeforthat
exam. Make-up exams will be prepared at the same or higher level than the original exam. The
formatofthemake-upexammaybewrittenororal.Failuretoattendascheduledmake-upexamwill
resultinazero(0)gradeforthatexam.StudentsmissinganexamduetoaUniversityapprovedexcuse
willtakethemake-upexamduringtheweekoffinals,orasdeterminedbythecoursecoordinator.
d.
Academic Integrity: Faculty and students must observe the ULM published policy on Academic
Dishonesty(seePage4oftheULMStudentPolicyManual-http://www.ulm.edu/studentpolicy/).All
professional students will adhere to the standards set forth in the School of Pharmacy’s Code of
Conduct(http://www.ulm.edu/pharmacy/documents/ospa/codeofconductv82011.pdf).
Censures(Penalties)
AcademicdishonestywillresultinareferraltotheCommitteeonEthicalandProfessionalStandards
witharecommendationforagradeof“F”forthecourseandexpulsionfromtheSchoolofPharmacy.
Academicdishonestyincludes,butisnotlimitedto,theuseofinformationtakenfromothers’work
or ideas, the provision of help to others on non-collaborative evaluations (tests, quizzes, etc.),
collaboration on take home exams, or the use of unapproved information or electronic devices to
assistinobtainingananswertothequestion
e.
f.
Course Evaluation Policy: At a minimum, students are expected to complete the on-line course
evaluation.
StudentServices:InformationconcerningstudentservicesintheSchoolofPharmacycanbefound
intheSchoolofPharmacyStudentHandbook.Inparticular,studentsshouldpayspecialattentionto
the University’s technical standards and policies concerning students with special needs
(http://www.ulm.edu/studentpolicy/studentpolicy.pdf).ULMstudentservices,suchastheStudent
SuccessCenter(http://ulm.edu/cass/),CounselingCenter(http://ulm.edu/counselingcenter/),and
Student Health Services, is available at the following Student Services web site
http://ulm.edu/studentaffairs/. Students with special needs requiring accommodations MUST
followtheprocessdescribedathttp://rxweb.ulm.edu/pharmacy/student/specialneeds.pdf.
MentalWellnessontheULMCampus
Ifyouarehavingproblemswithemotional,social,and/orbehavioralissuespleasecallanyofthe
mentalhealthclinicsontheULMcampustomakeanappointment.AllservicesarefreetoULM
students,staff,andfaculty,andarestrictlyconfidential.
• COPOfficeofStudentandProfessionalAffairs:342-3800
• ULMCounselingCenter:342-5220
• MarriageandFamilyTherapyClinic:342-5678
• CommunityCounselingCenter:342-1263
• ULMHELPS(HelpingEducatorsandLearnersPreventSuicide)ProjectOffice:342-1335
TheUniversityofLouisianaatMonroestrivestoservestudentswithspecialneedsthrough
compliancewithSections504oftheRehabilitationActof1973andtheAmericanswithDisabilities
Act.Theselawsmandatethatpostsecondaryinstitutionsprovideequalaccesstoprogramsand
servicesforstudentswithdisabilitieswithoutcreatingchangestotheessentialelementsofthe
curriculum.Whilestudentswithspecialneedsareexpectedtomeetourinstitution'sacademic
standards,theyaregiventheopportunitytofulfilllearneroutcomesinalternativeways.Examples
ofaccommodationsmayinclude,butarenotlimitedto,testingaccommodations(oraltesting,
extendedtimeforexams),interpreters,relocationofinaccessibleclassrooms,permissionto
audiotapelectures,note-takingassistance,andcoursesubstitutions.
TitleIXoftheEducationAmendmentsof1972prohibitssexdiscriminationagainstanyparticipantin
aneducationalprogramoractivitythatreceivesfederalfunds,includingfederalloansandgrants.
Furthermore,TitleIXprohibitssexdiscriminationtoincludesexualmisconduct,sexualviolence,sexual
harassmentandretaliation.Ifyouencounterunlawfulsexualharassmentorgender-based
discrimination,pleasecontactStudentServicesat318-342-5230ortofileacomplaint,visit
www.ulm.edu/titleix.
g.
EmergencyProcedures:Pleasereviewtheemergencyescapeplanintheclassroomsandhallways
oftheBienvillebuilding.Movequicklyandinanorderlymannertotheappropriatestairwelland
exitthebuilding.Themeetingplaceforthisclasswillbethefarendofthenorthparkinglot
betweentheBienvillebuildingandBroadmoorBlvd.Undernocircumstancesistheelevatortobe
usedforemergencyevacuation.Anystudentneedingassistanceshouldnotifytheprofessor
immediately.Foremergencies,tocontactUniversityPolice,call1-911fromlandlinesand3425350fromcellphones.
Thecoursecoordinatorsreservetherighttoadjustthesyllabusorschedule,inaccordancewithUniversity
andSchoolpoliciesandprocedures.
Lecture Topic
Instructor Date
MLKHoliday
M,Jan18
1
Calcium/Phos/VitaminDPharmacology Sylvester
W,Jan20
2
Calcium/PhosTherapeutics
Storer
M,Jan25
3
Calcium/PhosTherapeutics
Storer
W,Jan27
4
OsteoporosisAgents,Pharmacology
Sylvester
M,Feb1
5
OsteoporosisAgents,MedChem
Jois
W,Feb3
MardiGrasHoliday
M,Feb8
MardiGrasHoliday
W,Feb10
6
OsteoporosisTherapeutics
Posey
M,Feb15
7
VitaminDTherapeutics
Horace
W,Feb17
8
OtherBoneDisordersTherapeutics
Posey
M,Feb22
9
NSAIDs
,
MedChem
R.Hill
W,Feb24
10
GoutTherapeutics
Cockerham M,Feb29
TESTONE(1-9)
W,Mar2
11
OsteoarthritisTherapeutics
S.Hill
M,Mar7
12
OsteoarthritisTherapeutics
S.Hill
W,Mar9
13
OsteoarthritisTherapeutics
S.Hill
M,Mar14
14
OAActiveLearning/Cases
S.Hill
W,Mar16
15
DMARDs,MedChem
R.Hill
M,Mar21
16
RA/SLEBiologics,MedChem
R.HIll
W,Mar23
SpringBreak
M,Mar28
SpringBreak
W,Mar30
17
RheumatoidArthritisTherapeutics
Brady
M,Apr4
TESTTWO(10-16)
W,Apr6
18
RheumatoidArthritisTherapeutics
Brady
M,Apr11
19
Lupus(SLE)
Brady
W,Apr13
20
RA/LupusActiveLearning/Cases
Brady
M,Apr18
21
MyalgiaTherapeutics
Horace
W,Apr20
22
MyalgiaTherapeutics
Horace
M,Apr25
23
FibromyalgiaTherapeutics
Horace
W,Apr27
24
Osteosarcoma
Cockerham M,May2
ReviewDay
W,May4
FinalExam(17-24)
W,May11
(TimeTBA)
TentativeCourseSchedulePHRD5027BoneandJointModule
ClasswillmeetinBienville170MondayandWednesday,9:00-9:50am
Thefinalexamisnon-comprehensive.
Points Due
Date