Neonatal Air Leak Syndromes DR FAEZA SOOBADAR CONSULTANT PAEDIATRICIAN AND NEONATOLOGIST APOLLO-BRAMWELL HOSPITAL Air Leaks y Pneumothorax y Pneumomediastinum y Pneumopericardium p y Pneumoperitoneum y Subcutaneous emphysema p y y Pulmonary Interstitial Emphysema (PIE) y Air embolism P/thorax Air embolism PIE Alveolar rupture SCE P/mediastinum P/peritoneum P/pericardium Aetiology y Over-vigorous resuscitation y Intubation/ / IPPV// NCPAP y ‘Fighting’ ventilator y High g PIP;; Long g I.T y MAS; RDS; Pneumonia; Pulmonary hypoplasia Neonatal Pneumothorax Incidence y 1-1.5% 5 of all newborns y Affects 5-14% of babies admitted to NICUs y Males > Females y Terms = Pre-terms y Spontaneous p pneumothorax : 10/15,000 p / 5, y Bilateral in 10-21% y Mortality y 20% Clinical Presentation - 1 y Signs of respiratory distress: grunting, ↑RR, y y y y recession, cyanosis Apnoea, bradycardia, ↓BP Displaced apex beat Change in breath sounds ↑Ventilatory requirements Clinical Presentation - 2 y Sudden collapse p with severe hypotension, yp , bradycardia, apnoea, hypoxia, respiratory acidosis Investigations y CXR – AP, Lateral decubitus Investigations y CXR – AP, Lateral decubitus y Transillumination Investigations y CXR – AP,, Lateral decubitus y Transillumination y Direct needle aspiration p – diagnostic g & therapeutic p Treatment - 1 Conservative therapy +/- 100% oxygen y If no underlying y g lung g disease y No complicating therapy y No distress y No continuous air-leaks Resolve in 24-48 4 4 hrs Treatment – 2 Needle aspiration Equipment y 21-23G 3 butterflyy needle y Cleaning solution y Gallipot/ p / sterile water or y Syringe & 3-way tap Treatment – 2 Needle Aspiration Procedure y Clean skin y Insert needle 2nd/3rd ICS MCL y End of tubing g under water & watch for bubbles or y Apply continuous suction to syringe until rapid flow of air Treatment – 3 Thoracocentesis - Equipment y Chest drain 10 or 12FG mounted on trochar y Sterile gown/gloves & cleaning solution y LA, syringes & needles y Sterile dressing pack – fine mosquito forceps, scalpel/blade, large clamp scalpel/blade y Underwater seal drain y3 3-0/4-0 0/4 0 silk suture & transparent adhesive dressing Treatment – 3 Thoracocentesis - procedure y Clean area & inject LA y Make nick in skin along 4th/5th ICS MAL parallel to rib ib y Use fine mosquito forceps to make track for chest drain – just above rib below y Insert chest drain through track about 2-3cm, having previously withdrawn trochar from tip of chest drain Treatment – 4 Thoracocentesis - procedure y Place clamp on chest drain proximal to tip of y y y y y trochar & remove trochar completely Connect chest drain to underwater seal drain with 10-20 cm H2O suction pressure R Remove clamp l and d watch t h for f air i b bubbling bbli outt Suture chest drain in place C Cover with ith ttransparentt adhesive dh i d dressing i CXR Removal of chest drain y Lung disease has improved y Drained no air for 24-48hrs y Pneumothorax resolved for 24-48 hrs y No longer requiring PIP >25 y Stop suction, clamp drain & remove on successive days – CXRs y Remove during expiration if spontaneous breathing; p if vent’d inspiration Complications y Profound ventilatory & circulatory compromise & death y IVH y SIADH Pneumomediastinum DIAGNOSIS: DISTANT HEART SOUNDS +VE TRANSILLUMINATION CXR AP – SAIL SIGN LATERAL TREATMENT - CONSERVATIVE Pneumopericardium p CARDIAC TAMPONADE CXR ; TRANSILLUMINATION RX: PERICARDIAL TAPPING HIGH MORTALITY Audit on Neonatal Air Leaks SSRNH NICU 31.07.2001-31.07.2007 Incidence 56/1280 (4.3%) Gender 39 boys, 17 girls Place of birth SSRNH 22; JH 20; FH 7; Other 7 Mode of delivery Em CS 15; El CS 16; NVD 24; Forceps 1 Outcome 39 alive; 17 dead (Mortality 30%) Only 3 deaths directly attributable to airleak. Type & site of air-leak 2 2 15 30 8 Rt p/ p/thorax Lt p/thorax BL p/thorax P/mediastinum / P/pericardium Birth Weight 24 25 22 20 15 Numbers 10 8 5 2 0 <1 kg 1- <1.5 kg 1.5- <2.5 kg >=2.5 kg Gestation & Mortality 30 28 25 20 20 15 10 8 9 4 Total Died 4 5 Died 0 <32 wks Total 32-<37 wks >=37 wks Respiratory support prior to event 8 1 2 20 7 18 CMV/SIMV None NCPAP HFOV H d ventilated Hand til t d Unspecified Underlying diagnosis & Mortality 25 22 20 15 11 10 5 0 8 4 4 Total Died 5 3 4 3 0 1 1 1 1 1 1 1 2 Air leaks on admission = 16 3 1 8 2 1 1 RDS Pulm hypoplasia MAS TTN Pneumonia Spontaneous Outcome of survivors 10 Normal devt Delayed devt N follow-up No f ll 2 27 7 Summary & Recommendations y Multiple p aetiology gy & not specific p to NICU y Not always caused by ventilation y Beware p post-surfactant effect y ? Mortality y Very y low rate of CP y The undiagnosed & untreated pneumothoraces – future approach . Thank y you