Product datasheet Anti-hCG beta 1 epitope antibody [INN-hCG-2] ab11388 1 Abreviews 1 References Overview Product name Anti-hCG beta 1 epitope antibody [INN-hCG-2] Description Mouse monoclonal [INN-hCG-2] to hCG beta 1 epitope Specificity Clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains. Affinity constant = 4.8x108 L.mol-1. Tested applications IHC-P, ELISA, RIA Species reactivity Reacts with: Human Immunogen Human CG. Properties Form Liquid Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Storage buffer Preservative: 0.09% Sodium Azide Purity Protein A purified Clonality Monoclonal Clone number INN-hCG-2 Myeloma P3-NS1/1-Ag4-1 Isotype IgG1 Applications Our Abpromise guarantee covers the use of ab11388 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application Abreviews Notes IHC-P Use at an assay dependent concentration. ELISA Use at an assay dependent concentration. RIA Use at an assay dependent concentration. Application notes Is unsuitable for Flow Cyt. 1 Target Relevance Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. The beta subunit of chorionic gonadotropin (CG) is encoded by 6 highly homologous genes which are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta subunit gene. Cellular localization Secreted Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" Our Abpromise to you: Quality guaranteed and expert technical support Replacement or refund for products not performing as stated on the datasheet Valid for 12 months from date of delivery Response to your inquiry within 24 hours We provide support in Chinese, English, French, German, Japanese and Spanish Extensive multi-media technical resources to help you We investigate all quality concerns to ensure our products perform to the highest standards If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team. Terms and conditions Guarantee only valid for products bought direct from Abcam or one of our authorized distributors 2