Anti-hCG beta 1 epitope antibody [INN-hCG-2] ab11388

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Product datasheet
Anti-hCG beta 1 epitope antibody [INN-hCG-2] ab11388
1 Abreviews 1 References
Overview
Product name
Anti-hCG beta 1 epitope antibody [INN-hCG-2]
Description
Mouse monoclonal [INN-hCG-2] to hCG beta 1 epitope
Specificity
Clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked),
hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or
the glycoprotein hormone alpha chains. Affinity constant = 4.8x108 L.mol-1.
Tested applications
IHC-P, ELISA, RIA
Species reactivity
Reacts with: Human
Immunogen
Human CG.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw
cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Purity
Protein A purified
Clonality
Monoclonal
Clone number
INN-hCG-2
Myeloma
P3-NS1/1-Ag4-1
Isotype
IgG1
Applications
Our Abpromise guarantee covers the use of ab11388 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
IHC-P
Use at an assay dependent concentration.
ELISA
Use at an assay dependent concentration.
RIA
Use at an assay dependent concentration.
Application notes
Is unsuitable for Flow Cyt.
1
Target
Relevance
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells
of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first
trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the
ovary which is stimulated to produce progesterone which in turn maintains the secretory
endometrium. The beta subunit of chorionic gonadotropin (CG) is encoded by 6 highly
homologous genes which are arranged in tandem and inverted pairs on chromosome 19q13.3,
and contiguous with the luteinizing hormone beta subunit gene.
Cellular localization
Secreted
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
2
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