Product datasheet Anti-Luteinizing Hormone alpha antibody [ME.116] ab9506 Overview Product name Anti-Luteinizing Hormone alpha antibody [ME.116] Description Mouse monoclonal [ME.116] to Luteinizing Hormone alpha Specificity This antibody shows cross reactivity with: hCG-beta = <1% hCG-alpha = <32% hLH = <100% hFSH = <1% hTSH = <1% Affinity = 4 x 1010 Iso-electric Point = Range of 6.51 – 6.77 with a major band at 6.64 Tested applications ELISA Species reactivity Reacts with: Human Immunogen hLH-alpha, MW 39 kD Properties Form Liquid Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or 80°C. Avoid freeze / thaw cycle. Storage buffer Phosphate buffered saline Purity Protein A purified Purification notes This product is 0.22µm filtered Clonality Monoclonal Clone number ME.116 Isotype IgG1 Light chain type kappa Applications Our Abpromise guarantee covers the use of ab9506 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application Abreviews Notes ELISA Application notes Working dilutions are best determined by the user 1 Target Relevance The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Luteinizing hormone (LH) is a hormone synthesized and secreted by gonadotropes in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle stimulating hormone (FSH) it is necessary for proper reproductive function. In the female, an acute rise of LH triggers ovulation. In the male, where LH had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. Cellular localization Secreted Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" Our Abpromise to you: Quality guaranteed and expert technical support Replacement or refund for products not performing as stated on the datasheet Valid for 12 months from date of delivery Response to your inquiry within 24 hours We provide support in Chinese, English, French, German, Japanese and Spanish Extensive multi-media technical resources to help you We investigate all quality concerns to ensure our products perform to the highest standards If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit http://www.abcam.com/abpromise or contact our technical team. Terms and conditions Guarantee only valid for products bought direct from Abcam or one of our authorized distributors 2