Anti-Luteinizing Hormone alpha antibody [ME.116] ab9506

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Product datasheet
Anti-Luteinizing Hormone alpha antibody [ME.116]
ab9506
Overview
Product name
Anti-Luteinizing Hormone alpha antibody [ME.116]
Description
Mouse monoclonal [ME.116] to Luteinizing Hormone alpha
Specificity
This antibody shows cross reactivity with: hCG-beta = <1% hCG-alpha = <32% hLH = <100%
hFSH = <1% hTSH = <1% Affinity = 4 x 1010 Iso-electric Point = Range of 6.51 – 6.77 with a
major band at 6.64
Tested applications
ELISA
Species reactivity
Reacts with: Human
Immunogen
hLH-alpha, MW 39 kD
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or 80°C. Avoid freeze / thaw cycle.
Storage buffer
Phosphate buffered saline
Purity
Protein A purified
Purification notes
This product is 0.22µm filtered
Clonality
Monoclonal
Clone number
ME.116
Isotype
IgG1
Light chain type
kappa
Applications
Our Abpromise guarantee covers the use of ab9506 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application
Abreviews
Notes
ELISA
Application notes
Working dilutions are best determined by the user
1
Target
Relevance
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH),
follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting
of alpha and beta subunits that are associated noncovalently. The alpha subunits of these
hormones are identical. The protein encoded by this gene is the alpha subunit and belongs to
the glycoprotein hormones alpha chain family. Luteinizing hormone (LH) is a hormone
synthesized and secreted by gonadotropes in the anterior lobe of the pituitary gland. In concert
with the other pituitary gonadotropin follicle stimulating hormone (FSH) it is necessary for proper
reproductive function. In the female, an acute rise of LH triggers ovulation. In the male, where LH
had also been called Interstitial Cell Stimulating Hormone (ICSH), it stimulates Leydig cell
production of testosterone.
Cellular localization
Secreted
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Valid for 12 months from date of delivery
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Terms and conditions
Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
2
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