R&D Systems
Now Available Through
Fisher Scientific
R&D Systems High-quality
Reagents Now Available
through Fisher Scientific
Fisher Scientific has
enhanced their life
science portfolio with
the addition of the
R&D Systems product
lines, including Tocris
Bioscience and
Boston Biochem.
A leading supplier of cell biology reagents with over 25 years
of experience serving the research community, R&D Systems
develops and manufactures more than 95% of their products.
All materials are controlled to ensure that R&D Systems meets
the standards vital to delivering the highest quality products.
Areas of Research Covered:
•Cancer
•Cytokines and Growth Factors
•Developmental Biology
•Endocrinology
•Glycobiology
•Immunology
•Neuroscience
•Proteases and Other Enzymes
•Signal Transduction
•Stem Cells
•Ubiquitin, Related Modifiers,
and Pathways
Alkaline Phosphatase (O.D.)
R&D Systems Key Product Lines:
R&D Systems
2
Company 1
Company 2
1
kDa
92
66
55
43
Mouse Wnt-3a
(High Purity)
36
29
0.7
0.01
0.1
1
10
100
1000
22
18
Wnt-3a (ng/mL)
R&D Systems
2
Quantikine® ELISAs
– the gold standard in biomarker discovery
kDa
1
Tested with relevant bioassays to demonstrateCompany
biological
activity
•
Company
2
Mouse Wnt-3a
Refolded properly
•
(High Purity)
Confirmed high purity
•
Wnt-3a (ng/mL)
Consistent from lot-to-lot
•
Contain low endotoxin levels
•
Also available as Animal-Free and GMP-grade
92
66
55
Unstimulated Whole Blood
43
Stimulated 8 hours
36
1
0.7
0.01
0.1
1
10
100
Concentration (pg/mL)
•
•
•
•
•
•
Alkaline Phosphatase (O.D.)
Recombinant and Natural Bioactive Proteins
– the industry leading supplier
Stimulated 1 hour
29
10,000
1,000
1000
100
*
*
*
22
18
*
*
10
1
0
A
B
A
B
A B
A
B
A
B
IL-1β IL-12 IL-5 GM-CSF IL-2
A
B
IL-4
The most referenced ELISAs
Tested extensively for cross-reactivity
Provides accuracy, sensitivity, and specificity
Consistent from lot-to-lot
Manufactured at R&D Systems for full-control over development and quality control
Stimulated 24 hours
A PMA + Ca2+/Ionomycin-Stimulated
B LPS-Stimulated
A
B
IL-6
A
B
IL-8
A
B
A
IL-10
B
A
VEGF
B
A
IFN-γ
B
TNF-α
Concentration (pg/mL)
Cytokines
Unstimulated Whole Blood
Stimulated 8 hours
Stimulated 1 hour
10,000
1,000
100
*
Stimulated 24 hours
A PMA + Ca2+/Ionomycin-Stimulated
B LPS-Stimulated
*
*
*
*
10
1
0
A
B
A
B
A B
A
B
A
B
IL-1β IL-12 IL-5 GM-CSF IL-2
A
B
IL-4
A
B
IL-6
A
B
IL-8
A
B
IL-10
A
B
VEGF
A
B
IFN-γ
A
B
TNF-α
Cytokines
Application Qualified Antibodies
– from the leading supplier of proteins, over 10,000 antibodies
Raised against mature, full-length, and biologically-active proteins.
Manufactured in R&D Systems laboratories.
Validated by R&D Systems scientists for up to ten applications
Conjugated to an extensive selection of fluorochromes and non-fluorescent labels
•
•
•
•
Tocris is a high-quality provider of biologically active small molecules.
They offer a unique collection of over 3,000 life science biological
research products with strengths in neuroscience and cell signaling. The product range comprises small molecule and peptide agonists,
antagonists, and inhibitors, as well as controlled substances, toxins,
caged compounds, fluorescent probes, screening libraries, and ligand sets useful in many research areas.
KEY POINTS: High purity, extensive solubility information, competitive
pricing, respect for third-party intellectual property
Luminex® Performance and Screening Assays – from the world leader in immunoassay development Performance Assay:
All analytes in a given panel are optimized and tested together to ensure maximum performance for the entire panel
• Kits undergo similar validation testing and are correlated with the Quantikine ELISA
Screening Assay:
• Up to 100 human and 40 mouse analytes can be simultaneously profiled for ultimate flexibility
• The most cost-effective assay for profiling multiple markers
• The menu of analytes is rapidly expanding
•
Boston Biochem, Inc. is the leading global producer of ubiquitinrelated research products. Boston Biochem specializes in several
related product lines for ubiquitin and ubiquitin-like (UBL) proteins
(e.g. Apg8, FAT10, ISG15, NEDD8, SUMO, UFM1) and associated
enzymes, substrates, inhibitors and kits.
KEY POINTS: The most comprehensive ubiquitin-related product
range, unique content for UPP research not available from
any other source
In U.S.: www.fishersci.com/rndsystems
In Canada: www.fishersci.ca/rndsystems
© 2014 Thermo Fisher Scientific Inc. All rights reserved.
Trademarks used are owned as indicated at www.fishersci.com/trademarks.
In the United States:
For customer service, call 1-800-766-7000
To fax an order, use 1-800-926-1166
To order online: www.fishersci.com
13_1965
JA/JC
01/14
BN01141414
In Canada:
For customer service, call 1-800-234-7437
To fax an order, use 1-800-463-2996
To order online: www.fishersci.ca