Using Evidence to Design Benefits National Health Policy Conference February 9, 2010 Washington, D.C. Sam Nussbaum, M.D. Executive Vice President, Clinical Health Policy and Chief Medical Officer Key Drivers in Value-Based Care Establishing the Evidence Base Encourage ValueBased Decisions Develop Value-Based Benefit Designs Safety and Quality Drives Value Science-based policy and determining what works Inform on appropriate alternatives; close gaps in care Benefit structure, incentives, and increased management Emphasize drug, device, and medical safety 2 Establishing an Evidence-Base: Medical Policy • Medical policies promote evidence-based care and proven science • Continuous review of peer-reviewed medical research • Engage 33 medical specialty societies and academic medical centers • Apply published standards and considers community practice patterns • Available on WellPoint website; http://www.anthem.com ADVISORY COMMITTEE ON IMMUNIZATION PRACTICES 3 Outcomes Research and Comparative Effectiveness Research “Real World” Research Drives Quality, Cost Effective Care • Integrated data sources for outcomes research and analysis • Collaborative research relationships with premier academic centers • More than 110 research projects underway • Breast cancer, asthma, rheumatoid arthritis, low back pain, multiple sclerosis 4 WellPoint Position: CER Promotes Value and Innovation Collaboration amongst health care system stakeholders is central to making CER work • Address unsustainable health care costs • Limited resources threaten innovation SUPERIOR • Help patients choose more effective treatments • Fewer unnecessary services = health system savings COMPARABLE • Quality first, then affordability • Superior treatments deserve our nation’s investment • Comparable treatments should be chosen on value PERSONALIZED • Selectively effective personalized treatments should be managed by physicians and patients • Remove inappropriate/ineffective treatments INEFFECTIVE 5 Emerging Medical Technologies and Comparative Effectiveness Diagnosis and Treatment of Prostate Cancer is Controversial $ Dollars (thousands) 100 80 Even among radiation treatments, there is variation in cost and potential outcomes 60 40 20 0 3 -D C o n fo rm a l B ra c h y th e ra p y IM R T P ro to n B e a m Comparative effectiveness can assess outcomes, quality of life, and survival 6 Comparative Effectiveness: STATINS • Examined evidence for therapeutic substitution of generic simvastatin versus name brand medications • Results: • 63% of all members could be appropriately treated with generic simvastatin • Encouraged appropriate use of generic simvastatin through member/provider educations and incentives • Cost savings to members through lower co-payments Opportunity for add-on analyses of cardiac outcomes; ultimate goal of statins is to prevent cardiac events 7 Comparative Effectiveness: ASTHMA CONTROLLER MEDICATION • Clinical trials established inhaled steroids as most effective treatment • Convened national experts to study “real world” experience of 56K members $1,300 Predicted 12-month Total Cost $1,200 $1,100 $1,000 • Findings on oral medication use $900 • Higher compliance • Reduced asthma-related emergency room visits and hospitalizations ICS 8.5 LABA LM % Members With IP/ER Utilization 8 • Higher over-all cost due to cost of drugs 7.5 • Singulair® moved to more favorable tier, prior authorization removed • Best outcomes from compliant, combination prescription therapy 7 6.5 6 ICS LABA LM 8 Comparative Effectiveness: Treatment Options and Risks/Benefits • Facts on Back Pain • 9 of 10 Americans experience back pain • #1 cause of lost work productivity • Most pain resolves within 6 weeks independent of treatment • Study of 172,000 Anthem Members in 6 States • 1,000 surgeries during first 6 weeks • 35,000 imaging procedures within first 6 weeks $$ COST $$ • $90B spent nationally on treatment • Care dependent on initial treating physician • Value and Benefits • Collaboration with American Academy of Family Physicians • New payment models including bundling of payments • Educate members/physicians on treatment options 9 Encouraging Appropriate Generic Substitution • GenericPremium® Benefit Design • 20% cost reduction from all-generic formulary plus the 1-2 most popular branded drugs per drug class • Physician office generic drug dispensing kiosks (MedVantx) • Generic co-pay waivers Generic Dispensing Rates 80 75 70 65 60 55 • Member and physician education 2007 Commercial 2008 Medicare 2009 Medicaid 10 Appropriate Sites of Clinical Service: Case Study Comparative Costs for Non-Emergency Diagnoses $1000 Costs Retail Health Clinic Emergency Room $500 Urgent Care $0 Sinusitis Pharyngitis Otitis media Bronchitis Cold/flu/viral Urinary infection • Inappropriate ER visits result in higher cost, lower quality and risk to ER access for true emergencies • Nurse Hotline and on-line tools educate members on lower-cost alternatives • Increased member liability for non-emergency ER use versus co-pay at alternate/appropriate care settings 11 Closing Gaps in Evidence-Based Care: Informing the Patient 12 Value-Based Networks: Blue Distinction Centers of Excellence • Improved quality through outcome metrics $45,000 $35,000 • Reduced complications $25,000 • Programs $15,000 • Transplant Median Cost Per DRG Event $5,000 AMI • Bariatric Surgery CABG CABG+PCI CABG Readmissions/Complications • Cardiac Surgery 20% • Rare Complex Cancer • Orthopedics: Lower Back Pain • Spine, Hip, and Knee Surgery 16% 12% 8% 4% 0% Qualified facilities demonstrate $4K - $9K lower costs per event CABG Readmissions CABG Complications Non-Blue Distinction 13 Value-Based Benefit Design: Northeast State Case Study Preventive Outpatient Services • Telephonic diabetes education and support (TDES) program 80% • Incentives for medication compliance 40% • Waived diabetic medication/supplies co-pays • Steered patients to higher quality hospitals and physicians 60% 20% 0% HbA1c Eye exam TDES Nutrition & Weight Counseling Control • Preventive care exempt from deductible • Higher overall cost during study period $2,500 Pre/Post Study Utilization Costs $2,000 • Longer term follow-up may demonstrate savings due to: • Higher medication compliance • Higher utilization of preventive service $1,500 $1,000 $500 $0 Outpatient Pre‐TDES Prescriptions Post‐TDES 14 WellPoint Safety Sentinel System: Vioxx® Case Study 34 million members’ claims, pharmacy, and laboratory data enables population safety and public health research Signal Count Serious Adverse Events Analysis of our membership would have detected increased cardiovascular events within 3-6 months after FDA approval Threshold for Action to Reduce or Eliminate Patient Exposure Heart Attacks & Strokes Timeline Jan 1998 Jan 1998 Vioxx® History Hints of cardiovascular issues in clinical trials May 1999 May 1999 FDA Approved April 2001 April 2001 Sept 2004 Sept 2004 Vioxx removed from Market 15 Health.Care.Value Promoting health care quality, safety, and affordability through evidence-based care Determine “what works” in health care Promote value-based decisions through information and education Develop integrated, incentive-based benefit designs Create quality metrics and value-based networks 16