Revival of the IUD: Increased Use among U S Women Increased Use among U.S. Women with Employer‐Sponsored Insurance, * 2002 2007 2002‐2007 Xin Xu, Maurizio Macaluso, Lijing Ouyang, Andrzej Kulczycki, Scott Grosse * The findings and conclusions in this presentation have not been formally disseminated by the Centers for Disease Control and Prevention and should not be construed to represent any agency determination or policy. Overview Introduction Objectives of the Study Data and Methods d h d Results Discussions and Conclusions Introduction The intrauterine device (IUD) is a safe, highly effective and long‐lasting, but reversible family planning method. Worldwide, the IUD is the most popular reversible contraceptive method used among women of reproductive age (United Nations, 2006). ) In European countries, 10‐26% of women of reproductive age had used IUDs (United Nations, 2006). Data Data from the 2002 National Survey of Family Growth suggests that from the 2002 National Survey of Family Growth suggests that only 2‐3% women of reproductive age in the United States had used IUDs (Mosher et al., 2004). Introduction: (continued) Women who had recently used IUDs reported the highest rate of complete satisfaction among all reversible contraception users (Guttmacher telephone survey, 2004) . None None of IUD users reported dissatisfaction (Guttmacher of IUD users reported dissatisfaction (Guttmacher telephone telephone survey, 2004). Limited Limited information has been provided to demonstrate the trend of information has been provided to demonstrate the trend of IUD insertions and related medical expenditure in the United States after 2002. Overview Introduction Objectives of the Study Data and Methods d h d Results Discussions and Conclusions Obj ti Objectives of the Study f th St d The objective of this study was to evaluate trends in the p in incidence of IUD insertions and related medical expenditure the United States from 2002 to 2007, among the female population with employer-sponsored health insurance (ESI). Illustrate geographic and age variations in the incidence of IUD insertions. Explore the differences in the use of the copper IUD versus the LNG IUS. LNG-IUS. Overview Introduction Objectives of the Study Data and Methods d h d Results Discussions and Conclusions D t Data The The MarketScan MarketScan Commercial Claims and Encounter Enrolled Commercial Claims and Encounter Enrolled Population database from 2002 to 2007. Limit Limit the sample to females aged from 15 to 49 years old from large, the sample to females aged from 15 to 49 years old from large self‐insured employers. Identify Identify for IUD insertion procedures between Jan. 1, 2002 and Dec. for IUD insertion procedures between Jan 1 2002 and Dec 31, 2007 through a unique Current Procedural Terminology code (CPT code 58300). Used the codes of the Healthcare Common Procedure Coding System (HCPCS) for the claims of IUD devices (HCPCS code J7300 for the copper IUD and J7302 for the LNG‐IUS). IU d J 302 f h LNG IUS) Methods h d Incidence Estimation: Annual IUD insertion rates for women of reproductive age with ESI from 2002 to 2007. The numerator was the annual number of women having at least one reimbursed IUD insertion. The denominator was the annual number of women under ESI plans with IUD insertion coverage. Methods: continued Methods: continued The Definition of “Covered The Definition of Covered Plans Plans”:: If the ESI plan was identifiable from the MarketScan Benefit Plan D i d t b Design database (50%): (50%) (a) the insurance plan explicitly included the coverage for co t acept es ( 6%); contraceptives (16%); (b) at least one IUD insertion reimbursement had been documented for this insurance plan in a given year (34%). If the ESI plan was un‐identifiable from the MarketScan Benefit Plan Design database (50%): The percent of women with IUD coverage in identifiable plan was applied to the insured women to estimate number of women covered. Methods: continued Methods: continued St ti ti l M th d Statistical Methods: Extrapolating estimates to women of reproductive age with ESI in Extrapolating estimates to women of reproductive age with ESI in the U.S. Using MarketScan national weights generated from weighted samples from The Medical Expenditure Panel Survey. l f Th M di l E dit P lS All monetary terms have been inflated to 2007 dollars, using All monetary terms have been inflated to 2007 dollars using Consumer Price Index for medical care. Overview Introduction Objectives of the Study Data and Methods d h d Results Discussions and Conclusions IUD Insertion Rates: IUD Insertion Rates: 2002‐2007 2002 2003 2004 2005 2006 2007 Women reimbursed for IUD insertions Women with ESI plans that cover for IUD Insertions IUD Insertion Incidence (per 1,000 women) 70,851 93,723 118,859 , 158,880 228,912 306,592 34,148,034 35,264,344 36,266,253 , , 36,162,818 36,563,812 36,857,678 2.07 2.66 3.28 4.39 6.26 8.32 Close to 1 million women with ESI had IUD insertions in the United States between 2002 and 2007. The incidence of IUD insertions among women with ESI went up by approximately 3 times between 2002 and 2007. The IUD Insertion Rates: The IUD Insertion Rates: 2002 vs 2007 INCIDENCE_IN_2002 1 2 4 6 8 INCIDENCE_IN_2007 1 2 4 6 8 10 12 The Increases in IUD I Insertion Rates, 2002‐2007 ti R t 2002 2007 GROWTH_BETWEEN_2002_TO_2007 0.165917 - 3.768999 6.635840 - 7.163263 4.228762 - 5.397326 7.213403 - 8.969595 5.461743 - 6.551244 9.222190 - 14.278881 AVERAGE_ANNUL_GROWTH_RATES 0.852157 - 27.653100 63.116162 - 78.696475 29.915576 - 44.754635 78.912750 - 112.243442 48.815133 - 61.519500 118.364514 - 357.974088 Results The IUD insertion incidence was relatively higher in border States. The IUD insertion incidence was relatively higher in border States Except Hawaii (because of insufficient data) and other 3 states (North Dakota, Washington DC and Washington State), all states witnessed average annual growth rates of 25% or higher. The average annual growth rate ranged from 0.9% in North Dakota, to over 300.0% in Alabama, Arkansas, and West Virginia. The average annual growth rates were more pronounced in Southeastern states where IUD insertion incidences were quite low in 2002. IUD Insertion rates by y Quintiles The within State difference in insertion rates between 2002 and 2007 (Per 1 000 women ) The within State difference in insertion rates between 2002 and 2007 (Per 1,000 14 13 12 11 10 9 8 US Average Lowest 10 States 7 Lowmid 10 States Mid 10 States 6 MidHigh 10 States Highest 10 States 5 4 3 2 1 0 2002 2003 2004 2005 2006 2007 Results The The increase in the IUD insertion incidence among states in upper increase in the IUD insertion incidence among states in upper quintiles is the driven force of the nationally rapid growth. Among the 10 states in the first quintile, the insertion incidence increased from 3.0 in 2002 to 13.5 in 2007, roughly a 350% growth. Among the 10 states in the last quintile, the insertion incidence only increased from 2.3 to 5.6, representing approximately a 143.5% gro th growth. The incidence among the states in the last quintile had hardly moved after 2005. IUD Insertion Rates by Age Groups (Per 1 000 enrollees) (Per 1,000 18.00 16.00 14.00 12.00 10.00 Ages 15‐24 Ages 25‐34 8 00 8.00 Ages 34‐44 Ages 45‐49 6.00 4 00 4.00 2.00 0.00 2002 2003 2004 2005 2006 2007 Results The growth rates of the incidences were very similar across age groups. groups But the absolute age variations in the IUD insertion incidence in 2007 2007 were exaggerated because of the age difference in 2002. t db f th diff i 2002 The IUD insertion incidence among the age group of 25‐34 went from 4 in 2002 to 16 in 2007. Incidence Rates Incidence Rates the Copper IUD vs the LNG‐IUS pp (Per 1,000 enrollees) 9 8 7 6 5 the Incidence of IUD/IUS Patients the Incidence of Copper IUD Patients 4 the Incidenceof LNG‐IUS Patients 3 2 1 0 2002 2003 2004 2005 2006 2007 Results The insertion incidence of the LNG‐IUS went from 0.5 in 2002 to 6.0 in 2007. The insertion incidence of the copper IUD went from 0.8 to 1.4. The LNG‐IUS represented 37% of all IUDs inserted in 2002, more than 50% in 2003, and over 80% in 2007. The age variations in this growth of the relative share of the LNG‐ IUS were very small. Overview Introduction Objectives of the Study Data and Methods d h d Results Discussions and Conclusions Strengths Illustrate Illustrate the trend in IUD insertion Incidence from 2002 to 2007 the trend in IUD insertion Incidence from 2002 to 2007 using patient‐level claim data . The estimates represent 226.5 million women covered by ESI from 2002 to 2007. Demonstrate recent geographic and age variations in IUD insertions in the U.S. population. Reveal the difference in the insertion incidence of the copper IUD and the LNG‐IUS. Estimate the medical expenditure associated with IUD insertions in the U S population with ESI the U.S. population with ESI. Limitations The denominator was estimated by assuming the percent of women y g p with IUD coverage in un‐identifiable plans was identical to that of women that were identifiable. Missed female population who had ESI plans but did not have the coverage for IUD insertions (less than 10%). ESI plans might reimburse for the insertion procedure but not the p prescription of the IUD device (underestimation of the insertion p ( incidences of the copper IUD and the LNG‐IUS in the first two years). Provided Provided limited information on the purpose of the IUD insertion. limited information on the purpose of the IUD insertion Contraceptive or managing menstrual bleeding? Or a combination of both? Conclusions The The IUD insertion incidence among the population with ESI in the United IUD insertion incidence among the population with ESI in the United States had increased remarkably from 2002 to 2007, although the overall incidence was still low. Substantial geographic and age disparity existed in the IUD insertion g p incidences during this time period. The total medical expenditure associated with IUD insertions in this population increased from 26 7 million in 2002 to 169 2 million in 2007 population increased from 26.7 million in 2002 to 169.2 million in 2007, representing a 533% growth. Additi Additional research is needed to understand whether the recent growth l hi d dt d t d h th th t th in IUD insertions and the state variations in the insertion incidence were p p related to differences in provider attitudes and local policies.