Spring 2016 Chem 465 Biochem II Black Hills State University M, W, F 1:00-1:50, JS 143 Instructor: Dr. Micheal Zehfus Office: BSB 108 Phone 642-6028 Campus P.O. Box 9088 Office Hours: Posted on door Email: Michael.Zehfus@bhsu.edu Text and material: Lehninger Principles of Biochemistry Nelson & Cox Worth -Additional class material may be obtained either from my Web pages: www.bhsu.edu/michealzehfus look under Courses Tab (note the spelling of micheal) Description: A study of the fundamental principles governing the behavior of biochemical systems. Topics to be covered in the two semester sequence include the study of proteins, lipids, and carbohydrates, metabolic processes, biological oxidation and reduction processes, molecular aspects of DNA replication and repari pathways transcription and RNA processing, and protein translation. PreRequisite: Chem 464 Corequisite: Chem 465L Semester hours: 3 Objectives: This semester we will focus on metabolism and information pathways in the cell. In the section on metabolism we will study the overall principles of bioenergetics, and study the details of glycolysis, gluconeogenesis, the citric acid cycle and oxidative phosphorylation. In the section on information we will examine chromosomal structure, DNA, RNA, and protein metabolism and the regulation of gene expression. ADA Statement: Reasonable accommodations, as arranged through the Disabilities Services Coordinator, will be provided students with documented disabilities. Contact the BHSU Disabilities Services Coordinator, Jennifer Lucero, at 605-642-6099 (Woodburn 134), fax number 605-642-6095, or via email at Jennifer.Lucero@bhsu.edu for more information. Additional information can also be found at: http://www.bhsu.edu/StudentLife/Learning/DisabilityServices/tabid/162/Default.aspx Freedom in Learning: Under Board of Regents and University policy student academic performance may be evaluated solely on an academic basis, not on opinions or conduct in matters unrelated to academic standards. Students should be free to take reasoned exception to the data or views offered in any course of study and to reserve judgment about matters of opinion, but they are responsible for learning the content of any course of study for which they are enrolled. Students who believe that an academic evaluation reflects prejudiced or capricious consideration of student opinions or conduct unrelated to academic standards should contact the chair of the department in which the course is being taught to initiate a review of the evaluation. Course Outline: Week Date Sections of text covered 1 Jan 11 - 15 Chapter 14 2 20, 22 Chapter 14 (skim pentose phosphate pathway) (1/20 Last day to drop without a transcript entry) 3 25 - 29 Chapters 14 &15 4 Feb 1 - 5 Chapters 15 &16 5 8, 10, 12 Chapter 16 & 19 (Skip photosynthesis), EXAM I 6 17 & 19 Finish Chapter 19 7 22 - 26 Chapter 24 8 Feb 29 , March 2, 4 Chapter 25, EXAM II 7 - 11 Spring Break 9 14 - 18 Chapter 25 &26 - I am planning on going to the ACS national meeting this week, but I do not have a firm schedule yet. As a result the exact assignments will be flexible from this week onward 10 21 & 23 Chapter 26 11 28, thru April 1 Chapter 26 12 4, 6, 8 Chapter 27, EXAM III (4/5 Last day to drop with a “W”) 13 11- 15 Chapter 27 14 18 - 22 Chapter 28 15 25 - 29 Chapter 28, EXAM IV Final Exam: Thursday, May 5th, 11:30-1:00 Evaluation Tests Four hour exams are shown on the above schedule. Each hour exam is worth 100 points. The final will be a standardized ACS test covering the entire year of biochemistry worth 100 points. At this point I would like to use the following grading scheme: A 88-100% B 78-87% C 63-77% D 50-62% F <50% This may change if necessary. Homework Sapling Learning For every chapter there will be a homework assignment on Sapling Learning. The due date is Friday May 5th the day of the final. Each homework assignment is optional, but will count toward your point total in the following manner. I will take your % score for the homework and multiply it by 50 points. That number will then be added to your point total for the semester. 50 bonus points can bring you up a full letter grade. In Class There will be two required in-class homework assignments. These two assignments will contribute a total of 25 points toward your final grade. Quizzes Every week there will be a quiz on Sapling Learning. The quiz is based on the previous week’s homework and is required. The quizzes will be available only from midnight to midnight the following Sunday of each week. Again Sapling learning will give you feedback on how you are doing on each problem, but there is a 10% penalty every time you submit a wrong answer. Your average on the quizzes will contribute 75 points toward your final grade. If you cannot take the quiz during the designated time E-mail Dr. Z for an extension. Grading Summary Hour exams 4 x 100 Final Quizzes In Class Homework TOTAL Points required for: A B C D F 400 points 100 points 75 points 25 points 600 points 528 point minimum ($88%) 468 point minimum (78-88%) 378 point minimum (63-77%) 300 point minimum (50-62%) < 300 points (<50%) Now the Sapling Homework bonus. Take your average % on the Sapling Homeworks, multiply that by 50 points, and add those bonus points to your point total. Does that improve your grade on the above scale? Academic Dishonesty/Plagiarism Cheating and other forms of academic dishonesty run contrary to the purpose of higher education and will not be tolerated in this course. Academic dishonesty includes (but is not limited to) plagiarism, copying answers or work done by another student (either on an exam or on out-ofclass assignments), allowing another student to copy from you, and using unauthorized materials during an exam. Academic dishonesty is a serious offense and could result in failure on an assignment or course. To the extent possible, all incidents will be resolved in discussions between the student and faculty member. As necessary, the chair and then the dean may become involved to resolve the issue. If academic dishonesty is established, a report describing the incident and its resolution will be filed in the offices of the dean and provost. In cases where a satisfactory outcome is not achieved through this process, students may appeal to the University’s Academic Appeals Committee. Formal procedures for filing a complaint for academic misconduct are in the Student Conduct Code in the Student Handbook. Cheating and plagiarism are defined in Section 2, Part B, 1. Disciplinary sanctions are outlined in Section 3, Judicial Policies.