Chem 464 - Biochemistry I -3 credits
Black Hills State University
Fall 2015
M, W, F; 1:00-1:50, Young Center 206
Census Date: Last Day to Add/Drop Course without transcript entry – September 3, 2015
Last Day to Drop Course with an automatic “W” – November 6, 2015
CAAP (Proficiency Exam) Testing – October 30 – November 5, 2015
*This is a graduation requirement for all students – NO EXCEPTIONS.*
IDEA Surveys administered – November 18 – 24, 2015
Instructor:
Dr. Micheal Zehfus
Office: Life Science Building 108
Phone 642-6028
Campus P.O. Box 9088
Office Hours: Posted on office door
Email: michael.zehfus@bhsu.edu
Description:
A study of the fundamental principals governing the behavior of biochemical systems. Topics
covered in the two semester sequence include the study of proteins, lipids and carbohydrates,
metabolic processes, biological oxidations and reduction processes, molecular aspects of DNA
replication and repair pathways, transcription and RNA processing, and protein translation.
Prerequisite: Chem 326
Corequisite: Chem 464L
Course Objectives:
This course serves as a basic introduction to Biochemistry. In this semester the emphasis will be
placed on protein structure and function, enzymes, enzyme kinetics and coenzymes,
carbohydrates, nucleic acids, lipids, membranes, and an introductions to glycolysis.
Text and material:
Required: Lehninger Principles of Biochemistry, Nelson& Cox, 5th or 6th Ed, Freeman
Optional: 1. Lecture notebook for Lehninger Principles of Biochemistry
includes copies of all illustration in text for doodling and taking notes on in class
2. The Absolute, Ultimate guide to Lehninger
Study guide including answers to text problem, additional thought questions, etc.
Additional class material may be obtained on my web page www.bhsu.edu/michealzehfus
(Note the spelling micheal) under Courses - Biochemistry I.
Required: Sapling Learning (Online). You will be required to use Sapling Learning for
homework and quiz assignments. If this presents a financial hardship, please see Dr. Z.
Attendance:
I expect you to show up for all classes, and I will keep track of your attendance on Starfish.
While attendance at class will not directly effect your grade, I tend to be more helpful to a person
who regularly attends class.
If you have a conflict with an exam, please notify me before the exam so we can resolve the
problem. If you have to miss an exam due to illness or other emergency, please let me know
within 24 hours so we can reschedule.
Cheating and Plagiarism Policy:
Cheating and other forms of academic dishonesty run contrary to the purpose of higher education
and will not be tolerated in this course. Academic dishonesty includes (but is not limited to)
plagiarism, copying answers or work done by another student (either on an exam or on out-ofclass assignments), allowing another student to copy from you, and using unauthorized materials
during an exam. Academic dishonesty is a serious offense and could result in failure on an
assignment or course. To the extent possible, all incidents will be resolved in discussions
between the student and faculty member. As necessary, the chair and then the dean may become
involved to resolve the issue. If academic dishonesty is established, a report describing the
incident and its resolution will be filed in the offices of the dean and provost. In cases where a
satisfactory outcome is not achieved through this process, students may appeal to the
University’s Academic Appeals Committee.
Formal procedures for filing a complaint for academic misconduct are in the Student Conduct Code
in the Student Handbook. Cheating and plagiarism are defined in Section 2, Part B, 1. Disciplinary
sanctions are outlined in Section 3, Judicial Policies.
ADA Statement:
Reasonable accommodations, as arranged through the Disabilities Services Coordinator, will be
provided students with documented disabilities. Contact the BHSU Disabilities Services
Coordinator, Jennifer Lucero, at 605-642-6099 (Woodburn 134), fax number 605-642-6095, or via
email at Jennifer.Lucero@bhsu.edu for more information. Additional information can also be found
at:
http://www.bhsu.edu/StudentLife/Learning/DisabilityServices/tabid/162/Default.aspx
Freedom In Learning:
Under Board of Regents and University policy student academic performance may be evaluated
solely on an academic basis, not on opinions or conduct in matters unrelated to academic
standards. Students should be free to take reasoned exception to the data or views offered in any
course of study and to reserve judgment about matters of opinion, but they are responsible for
learning the content of any course of study for which they are enrolled. Students who believe
that an academic evaluation reflects prejudiced or capricious consideration of student opinions or
conduct unrelated to academic standards should contact the chair of the department in which the
course is being taught to initiate a review of the evaluation.”
Evaluation:
Homework
For every chapter there will be a homework assignment on Sapling Learning.
There are no due dates on the homeworks, so they can be done any time in the
semester, and you can do problems over and over until you get them right. Each
homework assignment is optional, but will count toward your point total in the
following manner. I will take your % score for the homework and multiply it by
50 points. That number will then be added to your point total for the semester. 50
bonus points can bring you up a full letter grade.
Quizzes
Every week there will be a quiz on Sapling Learning. The quiz is based on the
previous week’s homework and is required. The quizzes will be available only
from midnight to midnight the following Sunday of each week. Again Sapling
learning will give you feedback on how you are doing on each problem, but there
is a 10% penalty every time you submit a wrong answer.
Your average on the quizzes will contribute 50 points toward your final grade.
If you cannot take the quiz during the designated time E-mail Dr. Z for an
extension.
Non-Sapling homework
Later in the semester I have a few additional assignments that I will grade for
added points. When averaged together these homeworks will contribute 50 points
toward your grade
Tests
Three hour exams are shown on the schedule below. Each hour exam is worth
100 points. The final will worth 200 points. I use the following grading scheme:
Final Grade determination
300 points (3x100) hour exams
200 points for final
50 points Sapling quiz average
50 points Non-Sapling homework.
Total = 600 points
Based on the above 600 points, the final grade is determined by simply adding up your
scores on all tests, your Sapling quiz average x 50 points, and your non-Sapling
homework average x 50 points.
A
528 point minimum ($88%)
B
468 point minimum (78-88%)
C
378 point minimum (63-77%)
D
300 pint minimum (50-62%)
F
< 300 points (<50%)
Now the Sapling Homework bonus. Take your average % on the Sapling Homeworks,
multiply that by 50 points, and add those bonus points to your point total. Does that
improve your grade on the above scale?
Course Outline Biochem 464 Fall 2014:
Week Date
Sections of text covered
1
Aug 24 - 28
Chapter 2 Water
2
Aug 31 - Sept 4
Chapter 3 Amino Acids
3
Sept 9 - 11
Chapter 4 3-D Structure of Proteins
4
Sept 14 - 18
Chapter 4 Continued
5
Sept 21, 23
Chapter 5 Protein Function
Sept 25
1st hour exam
6
Sept 28, Oct 2
Chapter 6 Enzymes*
7
Oct 5 - 9
Chapter 6 Continued
8
Oct 14 & 16
Chapter 7 Carbohydrates and Glycobiology*
9
Oct 19 - 23
Chapter 7 & 8 Nucleotides and Nucleic Acids*
10
Oct 26 & 28
Chapter 8 & 10 Lipids*
Oct 30
2nd hour exam
11
Nov 2 - 6
Chapter 10 Continued
12
Nov 9 & 13
Chapter 11 Biological Membranes and Transport
13
Nov 16 - 20
Chapter 11 Continued
14
Nov 23
Chapter 12 Biosignaling
15
Nov 30 - Dec 4
Chapter 13 Principles of Bioenergetics
16
Dec 7
3rd hour exam
Dec 9
Study day
16
Dec 14
Comprehensive Final - 11:30-1:00 regular classroom
* Denotes chapters with possible required homework assignments
To sign up for Sapling Learning: go to the link: http://bit.ly/saplinginstructions