EMBnet Norway George Magklaras PhD RHCE Biotechnology Center of Oslo & The Norwegian Center of Molecular Medicine University of Oslo, Norway http://www.biotek.uio.no http://www.ncmm.uio.no http://www.no.embnet.org Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Agenda Our facility: users, equipment, services and activities What is a life science computing service environment? Who are the end users of life science computing and what do they expect? Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 EMBnet Norway overview Established in 1989. 123 users (mainly from Norway, some international members) 1 member of staff dedicated to provision of services to bioinformaticians/Life scientists In total: 128 processing cores, 768 GPU cores, 424 Gbytes of RAM, 45 TiBs of disk space Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Some of our users/ synergies Laboratory for Microbial Dynamics (LaMDa) http://www.mn.uio.no/farmasi/english/research/groups/lamda/index.html HT Chemical Biology Screening Platform http://www.biotek.uio.no/english/research/about/infrastructure/chemical-biology-services/ Donaldson Bioinformatics Group http://bioinformatics.uio.no/wiki/Donaldson_Group The High Performance Computing Group (VD) https://wiki.uio.no/usit/suf/vd/hpc/index.php/VD The Norwegian Proteomics Society http://norwegian-proteomics-society.uio.no Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Services overview Access (web/programmatic) Biological Databases (EMBOSS, GCG, MRS, R), NGS tools (Galaxy) Training: Courses plus Focus Groups GPU life science computing Development environment support (BioPerl/ C/C++, JAVA, svn) Provision of RDBMS servers (MySQL, Postgres) and application portal setup Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Training Hands on and formal courses as part of the UiO Curriculum ( MBV-INF 4410 MBV-INF 9410 MBV-INF 9410A) Course subjects include: Biological sequence database access Sequence analysis and processing access of datasets using Perl/Python/ Statistical analysis tools (R + bioconductor) Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Life science computing environment Provides tools to: store, manipulate and query Biological sequence and medical databases (MRS, EMBOSS). store and process HTS data integrate scientific instrument workflows into storage and information repositories (Galaxy, Pipeline Pilot) Host web portals for groups Safeguards the user data (privacy,availability, integrity) Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Life science computing environment (2) Provide consistent interfaces: web GUI command-line Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Life science computing environment (3) Provides tools to engage bioinformaticians to: develop code adapt existing code APIs (bioPerl/BioPython) , compilers/ interpreters, version control Allows them to answer questions/help people/users. Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Life science computing users medical researcher Y Web/ GUI Y proteomics/ structural biology Y Y N medium functional genomics Y Y N medium Bioinformatics Y Y Y little user type DBs CLI +Dev N Help needed a lot Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 GPU computing Massive acceleration of algorithms in the field of life sciences (SIMD) 20x - 200x. Based on the NVIDIA Tesla and Fermi GPU architectures First Fermi GPU service in Norway for life sciences. Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011 Questions? admin@embnet.uio.no and http://www.embnet.org/join/ContactRegistration Talleres Internacionales de Bioinformática - UNAM- Enero 2012 Sunday, December 18, 2011