CURRICULUM VITAE HANS-­‐PETTER HERSLETH Department of Biosciences
University of Oslo, P.O. Box 1066 Blindern,
N-0316 Oslo, Norway
Phone +47 22854631
E-mail: h.p.hersleth@ibv.uio.no
Education 2007
2004
2000
1998
Doctor Scientarum, Department of Chemistry, University of Oslo, Norway
Teacher Education Program, (one-year), Department of Teacher Education and School
Development, University of Oslo, Norway
Candidatus Scientiarum, Department of Chemistry, University of Oslo, Norway
Candidatus Magisterius, University of Oslo, Norway
Employment 2012-Present Researcher, Department of Biosciences, University of Oslo, Norway, with ~25%
teaching.
2012
Lecturer at Oslo Handelsgymnasium in 55% position
2007-2012
Post doc., Department of Molecular Biosciences, University of Oslo, Norway, with
~20% teaching. (June 2011-June 2012 employed in 30%)
2007
Temporary lecturer and researcher (25% per week, january-august), Department of
Chemistry, University of Oslo, Norway
2006-2007
Temporary College lecturer (38% per week), Faculty of Engineering, Oslo
University College, Norway
2000-2006
PhD Fellow with 40% teaching, Department of Chemistry, University of Oslo
Areas of Research Interest Protein crystallography, X-ray diffraction, radiation damage, single-crystal spectroscopic
techniques: UV-vis and Raman spectroscopy, metalloproteins, redox proteins, haem and
flavoproteins, hydrogen bonds, hydrophobic interactions, radicals, EPR
Other activities Organizing the Norwegian Chemistry Olympiad high-school competition (Norwegian Chemical
Society) since 2004.
1 of 12
Teaching Experience Methods in molecular biology MBV4020
University
& biochemistry II (10stp)
Autumn 2008, 2009, 2010, 2011, 2012, 2013
Course responsible, Lectures, exercises and lab, (X-ray
Diffraction and Spectroscopy parts),
BIOSTRUCT – Protein
crystal spectroscopy (5stp)
MBV9220
University
of Oslo
Autumn 2010, 2012
Course responsible, lectures, exercises and lab
Biomolecular Structures
(10stp)
KJM5310
University
of Oslo
Autumn 2004, Autumn 2005
Course responsible with all lectures and exercises
Spring 2007
Lectures and exercises
Autumn 2008, Spring 2009, Autumn 2011, 2013
Guest lecturer
Protein Crystallography
(10stp)
KJ-KJB234
KJM5300
University
of Oslo
Spring 2002, Spring 2003, Spring 2004
Some lectures and exercises, labcourse
Spring 2005
Course responsible, lectures, exercises, labcourse
Autumn 2009, Spring 2011
Thought subject as special curriculum for master students
Introduction to Chemistry
KJ050
University
of Oslo
Autumn 2001, Autumn 2002
Exercises and labcourse groups
General Chemistry
KJ100
University
of Oslo
Autumn 2000
Exercises and labcourse groups
Organic Chemistry I
KJM1011
University
of Oslo
Spring 2006
Labcourse groups
Precourse in Chemistry
for Engineering Students
FO933A
Oslo
University
College
Autumn 2006 and Spring 2007
Whole course: lectures, exercises, lab for three classes
Mathematics S1 & S2
Oslo
Spring 2012
Handelsgym Two classes
Chemistry Olympiad
Kjemi-OL
of Oslo
Seminar
One-day seminar on
Biochemistry for high-school
chemistry teachers
2004-present
Various teaching
2007 chemistry teachers in Telemark
2010 chemistry teachers in Oppland
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Awards 1999
2005
Norsk Hydro’s Price for Excellent Results in Chemistry (Cand. Mag. Degree), 1998-99.
Erice Poster Price 2005 for the most attractive poster at the 37th International School of
Crystallography “Evolving Methods in Macromolecular Crystallography”
Co-­‐supervision of Master-­‐ and PhD-­‐students Master students: Marta Hammerstad (2010), Silje Skråmo (2012), Marie Lofstad (2012)
PhD-students: Åsmund K Røhr (2010), Inger K. Olsbu (2014), Marta Hammerstad (2014), Marie
Lofstad (2016)
Censor activities Censor on master thesis: 2010: 2; 2011: 1; 2012: 4
Grants Norwegian Research Council FRINATEK / University of Oslo (2014), “Young Researcher Grant”,
two positions (PhD and Researcher) – 8000kNOK
Reviewing activities Metallomics (RSC, UK), BBSRC (Biotechnology and Biological Sciences Research Council, UK)
Long term visit February 2001 – August 2001: Institute of Pharmacology and toxicology, Karl Franzens
Universität Graz, Austria.
Short term visit Regularly colleting data at the synchrotrons mainly in Grenoble ESRF and Zürich SLS, but also in
Hamburg and Lund with 3-6 visits per year since 1999.
Research collaborations Involvement in following past and present research collaborations:
► Richard S. Magliozzo, Brooklyn College, New York, USA.
Catalase-peroxidase; Outcome: Paper 17.
► Volker Schünemann, University of Kaiserslautern, Germany.
Mössbauer and nuclear resonance vibrational spectroscopy; Outcome: Paper 6, 11 and 19.
► Kara L. Bren, Rochester University, USA.
Cytochrome c; Outcome: Paper 16.
► Ulf Ryde, Lund University, Sweden.
Quantum chemistry; Outcome: Papers 4, 5, 8 and 9.
► Christian Brix Follsted Andersen and Søren Moestrup, Århus University, Denmark.
Haptoglobin-haemoglobin and spectroscopy; Outcome: Paper 14.
► Wouter van Beek at the Swiss-Norwegian Beam Line at ESRF, France.
In-situ single-crystal spectroscopy; Outcome: manuscripts in preparation.
► Guillaume Pompidor and Martin Fuchs at the X10SA beamline at SLS, Switzerland,
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In-situ single-crystal spectroscopy; Outcome: manuscripts in preparation.
List of papers (Peer review) 19.
18.
17.
16.
15.
14.
13.
12.
11.
10.
9.
S. Rackwitz, I. Faus, M. Schmitz, H. Kelm, H.-J. Krüger, K.K. Andersson, H.-P. Hersleth,
K. Achterhold, K. Schlage, H.-C. Wille, V. Schünemann & J.A. Wolny. A New Sample
Enviroment for Cryogenic Nuclear Resonance Scattering experiments on Single Crystals
and Microsamples at P01, PETRA III.
Hyperfine Interactions (2014) In Press
M. Hammerstad, H.-P. Hersleth*, A.B. Tomter, Å.K. Røhr & K.K. Andersson. The
Crystal Structure of Bacillus cereus Class Ib Ribonucleotide Reductase Di-iron NrdF in
Complex with NrdI.
ACS Chem. Biol. 9, 526-437 (2014).
X. Zhao, H.-P. Hersleth, J. Zhu, K.K. Andersson & R.S. Magliozzo. Access channel
residues Ser315 and Asp137 in Mycobacterium tuberculosis catalase-peroxidase (KatG)
control peroxidatic activation of the pro-drug isoniazid.
Chem. Commun. 49, 11650-11652 (2013).
M. Can, J. Krucinska, G. Zoppellaro, N.H. Andersen, J.E. Wedekin, H.-P. Hersleth*, K.K.
Andersson, & K.L. Bren. Structural characterization of Nitrosomonas europaea
cytochrome c552 variants with marked differences in electronic structure.
ChemBioChem. 14, 1828-1838 (2013).
A.B. Tomter, G. Zoppellaro, N.H. Andersen, H.-P. Hersleth, M. Hammerstad, Å.K. Røhr,
G.K. Sandvik, K.R. Strand, G.E. Nilsson, C.B. Bell III, A.-L. Barra, E. Blasco, L. Le Pape,
E.I. Solomon & K.K. Andersson. Ribonucleotide reductase class I with different radical
generating clusters.
Coord. Chem. Rev. 257, 3-26 (2013) REVIEW.
C.B.F.Andersen, M. Torvund-Jensen, M.J. Nielsen, C.L. Pinto de Oliveira, H.-P. Hersleth,
N.H. Andersen, J.S. Pedersen, G.R. Andersen & S.K. Moestrup. Structure of the
haptoglobin-haemoglobin complex.
Nature 489, 456-459 (2012).
H.-P. Hersleth* & K.K. Andersson. How different oxidation states of crystalline
myoglobin are influenced by X-rays. For the special issue: Protein Structure and Function
in the Crystalline State: from X-ray to Spectroscopy.
Biochim. Biophys. Acta, Proteins Proteomics 1814, 785-796 (2011).
Å.K. Røhr, H.-P. Hersleth & K.K. Andersson. Tracking Flavin Conformations in Protein
Crystal Structures with Raman Spectroscopy and QM/MM Calculations.
Angew. Chem. Int. Ed. 49, 2324-2327 (2010).
K. Muffler, J.A. Wolny, H.-P. Hersleth, K.K. Andersson, K. Achterhold, R. Rüffer & V.
Schünemann. Installation of an IR/Raman measuring station at the ESRF for simultaneous
detection of vibrational and nuclear resonant scattering spectra.
J. Phys.: Conf. Ser. 217, 012004, 4pp, (2010).
G. Zoppellaro, K.L. Bren, A.A. Esign, E. Harbitz, R. Kaur, H.-P. Hersleth, U. Ryde, L.
Hederstedt & K.K. Andersson. Studies of Ferric Proteins with Highly Anisotropic/Highly
Axial Low Spin (S=1/2) Electron Paramagnetic Resonance Signals with Bis-Histidine and
Histidine-Methionine Axial Iron Coordination.
Biopolymers 91, 1064-1082 (2009) REVIEW.
H.-P. Hersleth, Y.-W. Hsiao, U. Ryde, C.H. Görbitz & K.K. Andersson. The Influence of
X-Rays on the Structural Studies of Peroxide-Derived Myoglobin Intermediates.
Chem. Biodiv. 5, 2067-2089 (2008) REVIEW.
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8.
7.
6.
5.
4.
3.
2.
1.
H.-P. Hersleth, Y.-W. Hsiao, U. Ryde, C.H. Görbitz & K.K. Andersson. The crystal
structure of peroxymyoglobin generated through cryoradiolytic reduction of myoglobin
compound III during data collection.
Biochem. J. 412, 257-264 (2008).
H.-P. Hersleth, A. Varnier, E. Harbitz, Å.K. Røhr, P.P. Schmidt, M. Sørlie, F.H.
Cederkvist, S. Marchal, A.C.F. Gorren, B. Mayer, T. Uchida, V. Schünemann, T. Kitagawa,
A.X. Trautwein, T. Shimizu, R. Lange, C.H. Görbitz & K.K. Andersson. Reactive
complexes in myoglobin and nitric oxide synthase.
Inorg. Chim. Acta 361, 831-843 (2008) REVIEW.
H.-P. Hersleth, T. Uchida, Å.K. Røhr, T. Teschner, V. Schünemann, T. Kitagawa, A.X.
Trautwein, C.H. Görbitz & K.K. Andersson. Crystallographic and spectroscopical studies
of peroxide-derived myoglobin compound II and Occurence of protonated FeIV-O.
J. Biol. Chem. 280, 23372-23386 (2007).
H.-P. Hersleth, U. Ryde, P. Rydberg, C.H. Görbitz & K.K. Andersson. Structures of the
high-valent metal-ion haem-oxygen intermediates in peroxidases, oxygenases and catalases.
J. Inorg. Biochem. 100, 460-476 (2006) REVIEW.
K. Nilsson, H.-P. Hersleth, T.H. Rod, K.K. Andersson & U. Ryde. The Protonation Status
of Compound II in Myoglobin, Studied by a Combination of Experimental Data and
Quantum Chemical Calculations: Quantum Refinement.
Biophys. J. 87, 3437-3447 (2004).
H.-P. Hersleth, B. Dalhus, C.H. Görbitz & K.K. Andersson. An iron hydroxide moiety in
the 1.35 Å resolution structure of hydrogen peroxide derived myoglobin compund II at pH
5.2.
J. Inorg. Biol. Chem. 7, 299-304 (2002).
C.H. Görbitz & H.-P. Hersleth. Selective solvent inclusion as a tool for mapping molecular
properties in crystal structures - a diethylstilbestrol example.
Acta Cryst. B56, 1094-1102 (2000).
C.H. Görbitz & H.-P. Hersleth. On the inclusion of solvent molecules in the crystal
structure of organic compounds.
Acta Cryst. B56, 526-534 (2000).
* Taking part as corresponding author
Other publications 2.
1.
Å.K. Røhr, H.-P. Hersleth & K.K. Andersson. Consequences of using X-rays when studying
redox cofactors. ESRF Highlights 2010, 100-101 (2011).
H.-P. Hersleth & K.K. Andersson. Structural Studies of Peroxide-Derived Myoglobin
Intermediates. SNBL Highlights 2008, 5 pp (2008)
Talks and oral presentations at conferences 2013
16th International Conference on Bioinorganic Chemistry Satellite Meeting on COST
CM1003, 24th July 2013, Grenoble, France. Using in situ single-crystal UV-vis and Raman
spectroscopy to study the effect of X-ray radiation damage on the crystal structures of haem
and flavoproteins. Hersleth, H.-P., Røhr, Å.K., Lofstad, M.,Hammerstad., M., Skråmo, S.,
Andersen, N.H., van Beek, W., Can, M., Zhao, X., Pompidor, G., Magliozzo, R.S., Bren, K.L.
& Andersson, K.K.
2013
COST CM1003 Biological oxidation reactions - mechanisms and design of new
catalysts - Workgroup meeting, 30th – 31st May 2013, Utrecht, Netherlands. Grasping
the Nature of Compound II in Myoglobin by Combining X-Ray Diffraction and in-situ
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2013
Light Absorption and Raman Spectroscopy. Hersleth, H.-P.
49th Norwegian Biochemical Society Contact Meeting, 31th January – 3rd February
2013, Lillehammer, Norway. Using in situ single-crystal UV-vis and Raman
spectroscopy to study the effect of X-ray radiation damage on the crystal structures of
haem proteins. Hersleth, H.-P., Røhr, Å.K., Lofstad, M., Skråmo, S., van Beek, W.,
Pompidor, G. & Andersson, K.K.
2012
The 27th European Crystallography Meeting (ECM27), 6th–11th August 2011, Bergen,
Norway. Radiation damage in haem and flavoproteins studied by in-situ single-crystal
spectroscopy. Hersleth, H.-P., Røhr, Å.K., van Beek, W., Pompidor, G. & Andersson, K.K.
Acta Cryst. A68, s135 (2012) Suppl.
2012
3rd Workshop on the Simultaneous Combination of Spectroscopies with X-ray
Absorption, Scattering and Diffraction Techniques, 4th–6th July 2012, Zürich,
Switzerland. Using in situ single-crystal UV-vis and Raman spectroscopy to study the
effect of X-ray radiation damage on the crystal structures of haem proteins. Hersleth, H.P., Lofstad, M., van Beek, W., Pompidor, G. & Andersson, K.K.
2012
Norwegian user meeting for synchrotron- and neutronresearch 2012. 30th – 31st
January 2012, Stavanger, Norway. Combining X-Ray Diffraction and in-situ Single-Crystal
UV-Vis and Raman Spectroscopy to Study Haem Proteins. Hersleth, H.-P., & Andersson, K.K.
2011
XXII Congress and General Assembly of the International Union of Crystallography,
22nd–30st August 2011, Madrid, Spain. Combining X-Ray Diffraction and in-situ
Spectroscopy to Study Haem Proteins. Hersleth, H.-P., Zhao, X., Magliozzo, R.S. &
Andersson, K.K. Acta Cryst. A67, C159-C160 (2011) Suppl.
2011
15th International Conference on Bioinorganic Chemistry (ICBIC15), 7th–12th August
2011, Vancouver, Canada. Grasping the Nature of the Myoglobin Compound II state by
combining X-Ray Diffraction and in-situ Light Absorption and Raman Spectroscopy. Hersleth,
H.-P., Andersen, N.H. & Andersson. K.K. J. Biol. Inorg. Chem. 16, S481 (2011) Suppl. 1
2011
17th International Conference on Cytochrome P450, 26th–30th June 2011, Manchester,
United Kingdom. Grasping the Nature of the Compound II state in Myoglobin by combining
X-Ray Diffraction and in-situ Single-Crystal UV-vis and Raman Spectroscopy.
2011
15th Annual Conference of the Swedish Structural Biology Network, 17th–20th June
2011, Tällberg, Sweden. Combining X-Ray Diffraction and in-situ Single-Crystal Light
Absorption and Raman Spectroscopy to Study Different Redox States of Myoglobin.
2010
10th European Conference on Biological Inorganic Chemistry, 22nd –26th June 2010,
Thessaloniki, Greece. Combining X-ray diffraction and in-situ light absorption and raman
spectroscopy to study different myoglobin redox states.
2009
Norwegian synchrotron user meeting 2009. 18th - 19th June 2009, Lillehammer,
Norway. Combining X-ray diffraction and spectroscopy to study the intermediates in the
reaction between myoglobin and peroxides.
2008
44th Norwegian Biochemical Society Contact Meeting, 17th –19th Jan 2008,
Lillehammer, Norway. On the Quest for Metalloprotein Reaction Intermediates in the
Radiation Damage Landscape of Protein Crystallography.
2008
The 8th International Peroxidase Symposium, 20th-24th August 2008, Tampere,
Finland. Structural studies of the intermediates in the reaction between myoglobin and
peroxides.
2007
19th Nordic Structural Chemistry Meeting, 8th-11th January 2007, Spåtind, Norway.
Combining protein crystallography and single crystal light absorption spectroscopy –
Structures of intermediates in the reaction between myoglobin and peroxides.
2006
2nd Meeting of the Protein Structure and Spectroscopy Subgroup of MedCoast
Scancdinavia, 25th-26th January 2006, Göteborg, Sweden. The second function of
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myoglobin. A structural study of the intermediates in the reaction between myoglobin and
peroxides.
2003
1st Meeting of the Protein Structure and Spectroscopy Subgroup of MedCoast
Scancdinavia, 14th-15th January 2003, Oslo, Norway. Structural Studies of the MyoglobinPeroxide Reaction.
2003
2nd Swiss-Norwegian Beam Line Highlights meeting, 23th–25th Jun 2003, Tromsø,
Norway. Trapping reaction intermediates in the myoglobin-peroxide reaction. A
crystallographic study supported by single crystal light absorption spectroscopy.
2002
38th Norwegian Biochemical Society Contact Meeting, 17th–20th Jan 2002, Røros,
Norway. High Resolution Crystal Structure of Intermediates Formed In Myoglobin-Peroxide
reactions.
2001
Norwegian Synchrotron Research User Meeting, 18th–19th January 2001, Gardermoen,
Norway. The Structure of the Myoglobin Compound II Intermediate Formed by Reaction with
Hydrogen Peroxide.
2000
Iron-Oxygen Protein Network Meeting, 14th–15th April 2000, Gardermoen, Norway.
Crystal Structure at 1.45 Å of the Ferryl Myoglobin (Compound II Model).
Posters presentations at conferences 2013
16th International Conference on Bioinorganic Chemistry (ICBIC16), 22nd–26th July
2013, Grenoble, France. Using in situ single-crystal UV-vis and Raman spectroscopy to
study the effect of X-ray radiation damage on the crystal structures of haem and flavoproteins.
Hersleth, H.-P., Røhr, Å.K., Lofstad, M.,Hammerstad., M., Skråmo, S., Andersen, N.H., van
Beek, W., Can, M., Zhao, X., Pompidor, G., Magliozzo, R.S., Bren, K.L. & Andersson, K.K.
2012
11th European Conference on Biological Inorganic Chemistry, 12th–16th September
2012, Granda, Spain. Using in situ single-crystal UV-vis and Raman spectroscopy to study
the effect of X-ray radiation damage on the crystal structures of haem and flavoproteins.
Hersleth, H.-P., Lofstad, M., Røhr, Å.K., van Beek, W., Can, M., Zhao, X., Pompidor, G.,
Magliozzo, R.S., Bren, K.L. & Andersson, K.K.
2012
16th Annual Conference of the Swedish Structural Biology Network, 15th–18th June
2012, Tällberg, Sweden. How fast are the redox and metallo sites in protein crystals reduced
by radiation damage during crystallographic data collection? Hersleth, H.-P. & Andersson,
K.K.
2012
7th International Workshop on X-ray Radiation Damage to Biological Crystalline Samples,
14th–16th March 2012, Oxford, United Kingdom. Using in-situ Spectroscopy to Study X-ray
Induced Radiation Damage to Haem Protein Crystals. Hersleth, H.-P., van Beek, W.,
Pompidor, G. & Andersson, K.K.
2010
1st Annual BioStruct Conference, 26th–29th August 2010, Inderøy, Norway. Combining protein
crystallography and in-situ single-crystal spectroscopy to determine the true redox states of
myoglobin crystals. Hersleth, H.-P. & Andersson, K.K.
2008
9th European Conference on Biological Inorganic Chemistry, 2nd – 6th September 2008,
Wroclaw, Polen. Structural Studies of the Intermediates in the Reaction Between Myoglobin
and Peroxides. Hersleth, H.-P., Hsiao, Y.-W., Ryde, U., Görbitz, C.H. & Andersson, K.K.
2006
38th International School of Crystallography: The Structure and Function of Large Molecular
Assemblies, 9th –18th June 2006, Erice (Sicilia), Italia. Structural Studies of intermediates in the
reaction between myoglobin and peroxides. Hersleth, H.-P., Uchida, T., Røhr, Å. K., Teschner,
T., Schünemann, V., Nilsson, K., Hsiao, Y.-W, Trautwein, A. X., Ryde, U., Görbitz, C. H.,
Kitagawa, T., & Andersson, K. K.
2006
8th European Conference on Biological Inorganic Chemistry, 2nd – 6th July 2006, Aveiro,
Portugal. Structural studies of intermediates in the myoglobin-peroxide reaction. Hersleth, H.P., Uchida, Røhr, Å. K., T., Teschner, T., Schünemann, V., Nilsson, K., Hsiao, Y.-W, Rod. T.
7 of 12
H.,.Trautwein, A. X., Ryde, U., Görbitz, C. H., Kitagawa, T., & Andersson, K. K.
2006
Peroxidase 2006 meeting 6th–9th July 2006, Aveiro, Portugal. Structures of intermediates in the
myoglobin-peroxide reaction. Hersleth, H.-P., Uchida, Røhr, Å. K., T., Teschner, T.,
Schünemann, V., Nilsson, K., Hsiao, Ya-wen, Trautwein, A. X., Ryde, U., Görbitz, C. H.,
Kitagawa, T., & Andersson, K. K.
2005
3rd Norwegian User Meeting – Application of Synchrotron Radiation, 10th – 11th March 2005,
Trondheim, Norway. Combination of protein crystallography and microspectrophotometry.
Trapping intermediates in the myoglobin-peroxide reaction cycle
Hersleth, H.-P., Uchida, T., Teschner, T., Røhr, Å. K., Schünemann, V., Nilsson, K., Hsiao,
Ya-wen, Trautwein, A. X., Ryde, U., Görbitz, C. H., Kitagawa, T., & Andersson, K. K.,
2005
37th International School of Crystallography: Evolving methods in macromolecular
crystallography, 12th –22nd May 2005, Erice (Sicilia), Italia. Structural Studies of the
intermediates in the myoglobin-peroxide reaction. Hersleth, H.-P., Uchida, T., Teschner, T.,
Røhr, Å. K., Schünemann, V., Nilsson, K., Hsiao, Ya-wen, Trautwein, A. X., Ryde, U.,
Görbitz, C. H., Kitagawa, T., & Andersson, K. K., P18, 198
2005
XX Congress and General Assembly of the International Union of Crystallography, 23rd–31st
August 2005, Florence, Italy. Structure of the intermediates in the myoglobin-peroxide
reaction. Hersleth, H.-P., Uchida, T., Teschner, T., Røhr, Å. K., Schünemann, V., Nilsson, K.,
Hsiao, Ya-wen, Trautwein, A. X., Ryde, U., Görbitz, C. H., Kitagawa, T., & Andersson, K. K.,
Acta Cryst. A61, C214 (2005).
2004
7th European Conference on Biological Inorganic Chemistry, 29th August – 2nd September
2004, Garmisch-Partenkirchen, Germany. Intermediates of the myoglobin-peroxide reaction –
A structural investigation. Hersleth, H.-P., Uchida, T., Teschner, T., Røhr, Å. K., Schünemann,
V., Nilsson, K., Hsiao, Ya-wen, Trautwein, A. X., Ryde, U., Görbitz, C. H., Kitagawa, T., &
Andersson, K. K., P106, 171
2002
6th European Conference on Biological Inorganic Chemistry, 29th July – 3th August 2002,
Lund, Sweden and Copenhagen, Denmark. Crystallographic and Spectroscopical Studies of
Peroxide-Derived Myoglobin Compound II. Hersleth, H.-P., Uchida, T., Teschner, T.,
Shünemann, V., Görbitz, C. H., Kitagawa, T., Trautwein, A. X. & Andersson, K. K., P180,
256
2002
XIX Congress and General Assembly of the International Union of Crystallography, 6th–15th
August 2002, Geneva, Switzerland. pH Dependence of Peroxide Derived High Valent Haem in
Myoglobin Studied by X-Ray Crystallography. Hersleth, H.-P., Dalhus, B., Görbitz, C. H. &
Andersson, K. K. Acta Cryst. A58 (Supplement), C117 (2002).
2001
17th Nordic Structural Chemistry Meeting, 7th–10th January 2001, Aarhus, Denmark.
The Structure of the Myoglobin Compound II Intermediate Formed by Reaction with
Hydrogen Peroxide. Hersleth, H.-P., Dalhus, B., Görbitz, C. H. & Andersson, K.K., P14.
2001
10th International Conference on Bioinorganic Chemistry, 26th–31th August 2001, Florence,
Italy. Compound II in Peroxidases: New Resonance Forms Suggested by pH Dependent
Structures of Intermediates Formed in Myoglobin-Peroxide Reactions. Hersleth, H.-P., Dalhus,
B., Görbitz, C. H. & Andersson, K. K. J. Inorg. Biochem. 86, 260-260 (2001).
Workshops 2009
2007
2006
2005
Summer School 2009 Computational Chemistry and Spectroscopy, 22nd -25th
September 2009, Essen, Germany
Course in MAD & SAD Data Collection and Phasing Workshop, 30th October–2th
November 2007, Lund, Sweden
38th International School of Crystallography: The Structure and Function of Large
Molecular Assemblies, 9th –18th June 2006, Erice (Sicilia), Italia.
37th International School of Crystallography: Evolving methods in macromolecular
crystallography, 12th –22nd May 2005, Erice (Sicilia), Italia.
8 of 12
2003
2002
2002
2001
Current Trends in Structure-Aided Drug Design Workshop, 22nd –24th May 2003,
Lund, Sweden.
Nordic Summer School in Synchrotron Radiation Research, 3rd –11th June 2002,
Smygehus/Lund, Sweden.
MedCoast Workshop on Expression & Structural Studies of Membrane Proteins, 28th –
29th October 2002, Göteborg, Sweden.
Application of Synchrotron Radiation in Chemsitry, Biology and Physics – NorFA
Research Training Course, 24th June –1st July 2001, Sønderborg, Denmark.
Other abstracts 2013
16th International Conference on Bioinorganic Chemistry (ICBIC16), 22nd–26th July
2013, Grenoble, France. In Crystallo Resonance Raman Spectroscopic Disclosure of the
Ferryl Stretching Mode in Myoglobin. Andersen, N.H., Hersleth, H.-P., Karlsson, A. &
Andersson, K. K.
2013
16th International Conference on Bioinorganic Chemistry (ICBIC16), 22nd–26th July
2013, Grenoble, France. The Bacillus cereus class Ib ribonucleotide reductase NrdI-Fe2NrdF protein complex structure favors a metal-dependent conformational basis for cofactor
activation. Hammerstad. M., Hersleth, H.-P., Tomter, A.B., Røhr, Å.K. & Andersson, K. K..
2013
16th International Conference on Bioinorganic Chemistry (ICBIC16), 22nd–26th July
2013, Grenoble, France. Nitric oxide synthase and possible redox partners in Bacillus cereus.
Lofstad, M, Hersleth, H.-P., Røhr, Å.K., Hammerstad, M., & Andersson, K.K.
2013
16th International Conference on Bioinorganic Chemistry (ICBIC16), 22nd–26th July
2013, Grenoble, France. Studies of the tyrosyl radicals and metal clusters in R2 of class Ia
and Ib ribonucleotide reductase. Hammerstad, M., Tomter, A.B., Hersleth, H.-P., Røhr, Å.K.,
Zoppellarro, G., Andersen, N.H., Sandvik, G.K., Strand, K.R., Nilsson, G.E., Barra., A.-L.,
Högbom, M., Gräslund, A. & Andersson, K. K.
2013
Chemistry of Metals in Biological Systems Summer School, 12th–19th May 2013,
Louvain-la-Neyve, Belgium. Nitric oxide synthase and possible redox partners in Bacillus
cereus. Lofstad, M, Hersleth, H.-P., Røhr, Å.K., Hammerstad, M., & Andersson, K.K.
2013
49th Norwegian Biochemical Society Contact Meeting, 31st–3rd February 2013, Lillehammer,
Norway. Crystal Structure of the B. cereus Class Ib Ribonucleotide Reductase NrdF Subunit in
Complex with the Flavoprotein NrdI. Hammerstad. M., Hersleth, H.-P., Røhr, Å.K. &
Andersson, K. K.
2013
49th Norwegian Biochemical Society Contact Meeting, 31st–3rd February 2013, Lillehammer,
Norway. Structural and functional studies of Nitric Oxide Synthase and Flavodoxines in
Bacillus cereus. Lofstad, M, Hersleth, H.-P., Røhr, Å.K., Hammerstad, M., & Andersson, K.K.
2013
49th Norwegian Biochemical Society Contact Meeting, 31st–3rd February 2013, Lillehammer,
Norway. Spectroscopic, structural and DFT studies of the tyrosyl radicals in R2F/R2/p53R2
subunits of ribonucleotide reductase. Tomter, A.B., Zoppellarro, G., Andersen, N.H., Hersleth,
H.-P., Hammerstad, M., Røhr, Å.K., Sandvik, G.K., Strand, K.R., Nilsson, G.E., Bell, C.B,
Barra., A.-L., Blasco, E., Le Pape, L., Solomon, E.I. & Andersson, K. K.
2013
Metals in Biology, Gordon Research Conference, 20th–25th January 2013, Ventura,
USA. Using in situ single-crystal UV-vis and Raman spectroscopy to study the effect of X-ray
radiation damage on the crystal structures of haem and flavoproteins. Hersleth, H.-P., Lofstad,
M., Røhr, Å.K., Can, M., Zhao, X., Pompidor, G., Magliozzo, R.S., Bren, K.L. & Andersson,
K.K.
2012
11th European Conference on Biological Inorganic Chemistry, 12th–16th September
2012, Granda, Spain. Structural and functional studies of Nitric Oxide Synthase and
Flavodoxines in Bacillus cereus. Lofstad, M, Hammerstad, M., Olsbu, I.K., Røhr, Å.K.,
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Hersleth, H.-P. & Andersson, K.K.
2012
11th European Conference on Biological Inorganic Chemistry, 12th–16th September
2012, Granda, Spain. Studies of the class Ib ribonucleotide reductase system in Bacillus
cereus and Mycobacterium tuberculosis. Hammerstad. M., Hersleth, H.-P., Røhr, Å.K.,
Högbom, M., Gräslund, A. & Andersson, K. K.
2012
2012
3rd Workshop on the Simultaneous Combination of Spectroscopies with X-ray
Absorption, Scattering and Diffraction Techniques, 4th–6th July 2012, Zürich,
Switzerland. Monitoring flavin X-ray radiation damage using single crystal
spectroscopy. Røhr, Å.K., Hersleth, H.-P., Pompidor, G. & Andersson, K.K.
16th Annual Conference of the Swedish Structural Biology Network, 15th–18th June
2012, Tällberg, Sweden. Structural and Spectroscopic Characterization of Nitric Oxide
Synthase and Flavodoxines in Bacillus cereus. Lofstad, M, Hammerstad, M., Olsbu, I.K.,
Røhr, Å.K., Hersleth, H.-P. & Andersson, K.K.
2012
16th Annual Conference of the Swedish Structural Biology Network, 15th–18th June
2012, Tällberg, Sweden. Structural and spectroscopic studies of electron transport from FldR
to the Ribonucleotide reductase system in B. cereus. Skråmo, S, Hersleth, H.-P., Hammerstad,
M., Røhr, Å.K., Tomter, A.B. & Andersson, K.K.
2012
45th International School of Crystallography: Present and Future Methods in Macromolecular
Crystallography, 31st –10th June 2012, Erice (Sicilia), Italia. Studies of the class Ib
ribonucleotide reductase system in Bacillus cereus and Mycobacterium tuberculosis.
Hammerstad. M., Hersleth, H.-P., Røhr, Å.K., Högbom, M., Gräslund, A. & Andersson, K. K.
2012
Norwegian user meeting for synchrotron- and neutronresearch 2012. 30th – 31st
January 2012, Stavanger, Norway. Biochemical and Structural Characterization of the
Bacillus cereus Thioredoxin BC3987. Hammerstad. M., Røhr, Å.K., Hersleth, H.-P., Tomter,
A.B. & Andersson, K.K.
2012
Norwegian user meeting for synchrotron- and neutronresearch 2012. 30th – 31st
January 2012, Stavanger, Norway. Structural studies of Nitric Oxide Synthase and
Flavodoxines in Bacillus cereus. Lofstad, M, Hammerstad, M., Olsbu, I.K., Røhr, Å.K.,
Hersleth, H.-P. & Andersson, K.K.
2012
Norwegian user meeting for synchrotron- and neutronresearch 2012. 30th – 31st
January 2012, Stavanger, Norway. Structural and spectroscopic studies of electron transport
from FldR to the Ribonucleotide reductase system in B. cereus. Skråmo, S, Hersleth, H.-P.,
Hammerstad, M., Røhr, Å.K., Tomter, A.B. & Andersson, K.K.
2011
2nd Annual BioStruct Conference, 1st–4th September 2011, Inderøy, Norway. Structural studies
of Nitric Oxide Synthase and Flavodoxines in Bacillus cereus. Lofstad, M, Hammerstad, M.,
Olsbu, I.K., Røhr, Å.K., Hersleth, H.-P. & Andersson, K.K.
2011
2nd Annual BioStruct Conference, 1st–4th september 2011, Inderøy, Norway. Structural and
spectroscopic studies of electron transport from FldR to the RNR system in B. cereus. Skråmo,
S, Hersleth, H.-P., Hammerstad, M., Røhr, Å.K., Tomter, A.B. & Andersson, K.K.
2011
14th European Conference on the Spectroscopy of Biological Molecules, 29th August –
3rd September 2011, Palermo, Italy. Combining X-ray diffraction and vibrational
spectroscopy in structural biology. Pompidor, G., Dworkowski, F.S.N., Thominet, V., Hersleth,
H.-P., Schulze-Briese, C. & Fuchs, M.
2011
XXII Congress and General Assembly of the International Union of Crystallography,
22nd–30st August 2011, Madrid, Spain. Combination of in-situ optical and macromolecular
crystallography. Pompidor, G., Dworkowski, F.S.N., Thominet, V., Hersleth, H.-P. & Fuchs,
M. Acta Cryst. A67, C555-C556 (2012) Suppl.
2011
15th International Conference on Bioinorganic Chemistry (ICBIC-15), 7th –12th August
2011, Vancouver, Canada. Biochemical and Structural Characterization of the Bacillus
cereus Thioredoxin BC3987. Hammerstad. M., Røhr, Å.K., Hersleth, H.-P., Tomter, A.B. &
10 of 12
Andersson, K.K. J. Biol. Inorg. Chem. 16, (2012) Suppl. 1
2011
17th International Symposium on Flavins and Flavoproteins, 24th–29th July 2011, Berkley,
USA. Monitoring protein bound flavin X-ray radiation damage. Røhr, Å.K., Hersleth, H.-P. &
Andersson, K.K.
2011
47th Norwegian Biochemical Society Contact Meeting, 3rd–6th Feb 2011, Tromsø, Norway. Key
role of Val567 on L-Arginine analogues and heme ligands binding to nNOS. Olsbu. I.K.,
Lombard, M., Hersleth, H.-P., Tomter, A.B. & Andersson, K.K. & Boucher, J.-L.
2011
47th Norwegian Biochemical Society Contact Meeting, 3rd–6th Feb 2011, Tromsø, Norway.
Biochemical and Structural Characterization of the Bacillus cereus Thioredoxin BC3987.
Hammerstad. M., Røhr, Å.K., Hersleth, H.-P., Tomter, A.B. & Andersson, K.K.
2010
10th European Conference on Biological Inorganic Chemistry, 22nd –26th June 2010,
Thessaloniki, Greece. Biochemical and Structural Characterization of the Bacillus cereus
Thioredoxin BC3987 Mutants. Hammerstad. M., Røhr, Å.K., Hersleth, H.-P., Tomter, A.B. &
Andersson, K.K.
2010
1st Annual BioStruct Conference, 26th–29th August 2010, Inderøy, Norway. Biochemical and
Structural Characterization of the Bacillus cereus Thioredoxin BC3987 Mutants. Hammerstad.
M., Røhr, Å.K., Hersleth, H.-P., Tomter, A.B. & Andersson, K.K.
2010
10th European Conference on Biological Inorganic Chemistry, 22nd –26th June 2010,
Thessaloniki, Greece. Structural and spectroscopic studies of the intermediates in the reaction
between myoglobin and peroxides, and of HALS proteins. Hersleth, H.-P., Zoppellaro, G.,
Bren, K.L. & Andersson, K.K.
2010
10th European Conference on Biological Inorganic Chemistry, 22nd –26th June 2010,
Thessaloniki, Greece. Key role of Val567 on L-Arginine analogues and heme ligands binding
to nNOS. Olsbu, I.K., Lombard, M., Hersleth, H.-P., Andersson, K.K. & Boucher, J.-L.
2010
1st Annual BioStruct Conference, 26th–29th August 2010, Inderøy, Norway. Key role of Val567
on L-Arginine analogues and heme ligands binding to nNOS. Olsbu, I.K., Lombard, M.,
Hersleth, H.-P., Andersson, K.K. & Boucher, J.-L.
2010
1st Annual BioStruct Conference, 26th–29th August 2010, Inderøy, Norway. Probing X-ray
induced conformational changes of flavin cofactors in protein.. Røhr, Å.K., Hersleth, H.-P., &
Andersson, K.K.
2010
6th International Workshop on X-ray Radiation Damage to Biological Crystalline Samples,
11th–13th March 2010, Stanford, USA. Probing X-ray induced conformational changes of flavin
cofactors in protein.. Røhr, Å.K., Hersleth, H.-P., & Andersson, K.K.
2010
Gordon Research Conferences: Metals In Biology, 31st January – 5th Feb 2010, Ventura, USA.
Nuclear inelastic scattering of the NO-carrier protein nitrophorin and of high-valent iron(IV)
myoglobin single crystals. Janoschka, A., Wolny, J.A., Moeser, B., Muffler, K., Berry, R.E.,
Walker, F.A., Hersleth, H.-P., Andersson, K.K., Achterhold, K. & Schünemann, V.
2010
Deutsche Tagung für Forschung mit Synchrotronstrahlung, Neutronen und Ionenstrahlen an
Großgeräten. Inelastiche kernstreuung and proteinkristallen. Hersleth, H.-P., Andersson, K.K.,
Muffler, K., Wolny, J.A., Achterhold, K., Rüffer, R. & Schünemann, V.
2009
45th Norwegian Biochemical Society Contact Meeting, 29th January–1st February 2009, Røros,
Norway. Structural studies of the intermediates in the reaction between myoglobin and
peroxides; effects of cryoradiolytic reduction. Andersson, K.K., Hsiao, Y.-W., Görbitz, C.H.,
Ryde, U., & Hersleth, H.-P.
2009
14th International Conference on Bioinorganic Chemistry (ICBIC14), 25th–30th July
2009, Nagoya, Japan. Structural studies of the intermediates in the reaction between
myoglobin and peroxides; effect of cryoradiolytic reduction. Andersson, K. K. & Hersleth, H.P. J. Biol. Chem. 114, S40, (2009) Suppl. 1.
2009
13th Annual Conference of the Swedish Structural Biology Network, 12th–15th June 2010,
Tällberg, Sweden. Structural studies of the intermediates in the reaction between myoglobin
and peroxides; effects of cryoradiolytic reduction. Hersleth, H.-P. & Andersson, K.K.
11 of 12
2008
233rd National American Chemical Society Meeting, 25th Feb – 1st March 2008, Chicago, USA.
Reactive complexes in myoglobin and nitric oxide synthase. Andersson, K.K, Agasøster, A.V.,
Harbitz, E., Røhr, Å.K., Sørlie, M., Görbitz, C.H. & Hersleth, H.-P.
2006
20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB
Congress, 18th–23rd June 2006, Kyoto, Japan. Crystallographic and spectroscopic studies of
two of the intermediates in the myoglobin-peroxide reaction. Andersson, K. K., Hersleth, H.-P.,
Uchida, T., Røhr, Å. K., Teschner, T., Schünemann, V., Nilsson, K., Hsiao, Ya-wen,
Trautwein, A. X., Ryde, U., Kitagawa, T. &. Görbitz, C. H.
2005
15th IUPAB & 5th EBSA International Biophysics Congress, 27th August – 1st September 2005,
Montpellier, France. High resolution crystal structures of two of the intermediates in the
peroxide reaction of myoglobin. Hersleth, H.-P., Uchida, T., Teschner, T., Røhr, Å. K.,
Schünemann, V., Nilsson, K., Hsiao, Ya-wen, Trautwein, A. X., Ryde, U., Görbitz, C. H.,
Kitagawa, T. & Andersson, K. K., . Eur. Biophys. J. 34, 661 (2005)
2005
11th International Conference on Bioinorganic Chemistry, 31th July – 5th August 2005, Ann
Arbor, USA. High resolution crystal structures of two of the intermediates in the myoglobin
peroxide reaction. Hersleth, H.-P., Uchida, T., Teschner, T., Røhr, Å. K., Schünemann, V.,
Nilsson, K., Hsiao, Y.-W., Trautwein, A. X., Ryde, U., Görbitz, C. H., Kitagawa, T. &
Andersson, K. K., .
2001
37th Norwegian Biochemical Society Contact Meeting, 18th–21th Jan 2001, Beito, Norway
High Resolution Structures of a Model for Compound II in Peroxidases Obtained From
Hydrogen Peroxide Incubation with Myoglobin at Different pH. Hersleth, H.-P., Dalhus, B.,
Görbitz, C. H. & Andersson, K.K., SF4.
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