This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this site. Copyright 2011, The Johns Hopkins University, Maria Segui-Gomez, and Adnan Hyder. All rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided “AS IS”; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as needed. Section B: Measuring Exposure Maria Segui-Gomez, MD, MPH, ScD What Do We Mean by Exposure? Practically anything we do That is, situations where individuals interact with an environment that can eventually generate energy that could lead to an injury - For example, population, distance traveled, hours traveled, intersections crossed, takeoffs/landings undergone, hours practicing soccer, minutes spent using a saw, etc. . . . 3 Relevance of Exposure Data Exposure is the denominator Needed for risk calculations 4 An Example 4.1 North America 9.5 Europe 11.4 Middle East Commercial jet crashes per million takeoffs/ landings 18.3 Asia 20.6 Eastern Europe 30.2 Africa 32.4 Latin America 0 Source: Enders, K. et al. (1996). Flight Safety Digest, 9. 10 20 30 40 5 Another (Fictional) Example Country A has fewer child passenger deaths per 100,000 population than country B Why? Possible explanations - Better child restraint use, fewer parents driving intoxicated, fewer children in cars, etc. . . . How to look for explanations 6 Country A vs. Country B Fatalities Acute care received, severity of injuries, frequency, type 7 Country A vs. Country B Fatalities Morbidity Acute care received, severity of injuries, frequency, type Severity of crash, frequency, type 8 Country A vs. Country B Fatalities Morbidity Events Acute care received, severity of injuries, frequency, type Severity of crash, frequency, type Frequency, type 9 Country A vs. Country B Fatalities Morbidity Events Acute care received, severity of injuries, frequency, type Severity of crash, frequency, type Frequency, type Exposure 10 How Does It All Come Together? An Example Children No Yes No Occupants? Crashes? Yes No Injuries? Yes No Injury Yes No Hospitalization Yes Deaths Disability 11 Data Sources When population—census For all other exposure units—multiple data sources specific to injury problem and location In general - Personal surveys - Observational studies - Estimates from goods bought (and average usage) 12 Data Coding Fragmented Among the most commonly used are vehicle miles (kilometers) traveled, derived from either - Personal diaries/surveys - National estimates of fuel used and average fuel consumption per mile 13 Data Coding Units tend to be big since injuries follow a Poisson distribution (that is, their frequency is rare) 14 Exposure Data Comparability Beware of - Data source variability - Case inclusion criteria - Coding system variability 15