" Gene Therapy Case Study Introduction: In the year 2005, the Hu.an Genome Project (HGP) reached completion, and knowledge gained from it is now profoundly affecting society. The chromosomal locus and function of every human gene has been determined, and the practice of gene therapy--the insertion of genes into a huaan being with the usual intent o£ replacing faulty or disease-causing genes with healthy ones--is now co •• onmplace. Gene therapy is of great benefit both to those who presently suffer from genetic afflictions and to those who are known to have genetic predispositions for certain diseases. Applications o£ the HGP which are not medically-oriented are being proposed however, and it is in these instances that new ethical con£licts arise • •••••••••••••••••••••••••••••••••••••••••••• *** ••••••••••••• It is the year 2006, and the students at Lindrix University, a prestigious Ivy League school, are competing with institutions nationwide £or a $100 million scholarship grant. The award will be given to the university whose students have the highest overall collective grade-pointaverage. Both students and faculty have great incentive to win this grant, as it will mean a chance for decreased tuition cost (not to mention prestige) for currently 66 -67 enrolled students and will also serve to help the University attract some of the nation's most intelligent and talented incoming fresh_en. Competition is intense, but the Lindrix co-eds have an excellent chance of being named the recipient. Extra tutorials are offered, and review sessions are scheduled for all classes. Ca_pus library hours are also extended, with the hope that these provisions will help enable students to raise their GPA's. In further pursuit of the scholarship grant, the administrative executives hold a special staff _eeting to explore additional methods of boosting the collegians' grades. The President proposes that the University take advantage of gene therapy and incorporate the genes known for superior intelligence and motivation into some of the students. Because gene therapy is very expensive, the administration realizes that it will not be possible for every student at the University to undergo the procedure. After much deliberation, the administration decides that the students whose parent(s) are professors at Lindrix should be the ones persuaded to undergo gene therapy. They support their decision with the reasoning that these parents can best afford the procedure since they receive appreciable salaries, and also since their sons and daughters attend Lindrix tuition-free. When the administration informs the faculty of their decision, most of those affected have strong reservations about the proposal. Many state that they will refuse to permit their children to undergo this type of therapy, maintaining that 68 1 they do not agree with genoae alterations for such unessential. nonmedical purposes. In response to this opposition. the adainistration announces plans to increase salaries for the professors who agree to their wishes. As further coercion. they threaten to fire those who are unwilling to cooperate. Although some parents adhere firmly to their initial stance and refuse to submit to the University's demands. others feel forced to comply because they feel that the financial constraints conferred by refusal would be too great. In addition to the parents' objections, many of the involved students voice disapproval for similar reasons. Others. however. are very willing--even eager--to undergo gene therapy, realizing that their grades will probably improve as a direct result. without any extra effort required on their part! Thus, they anticipate a likely advantage in getting accepted to graduate schools and in pursuing employ.ent. This results in conflict between some of these students and their parents. who seek to prevent them from receiving the therapy. Furthermore. some .arried students and their spouses also dispute the issue. especially since the therapy can potentially alter the germ line. thus affecting the genes o£ any future children that they might have. Further complication of the situation arises when news o£ the University's plans reaches the other competing schools. They accuse Lindrix o£ "cheating" and even use the 1990's analogy o£ steroid abuse by athletes to refer to their intentions. Lindrix administrators. however, 69 stand £ira in their decision p stating that they are aerely preparing their students £or coapetition in the best way that they can. In their de£ense p they argue that their action is completely £air since other schools could also use the technology i£ they desired to do so. They also deny the use o£ the steroid analogy as applicable p pointing out that the process o£ gene therapy does not involve illegal drugs. Thus p they continue to assert that their employment o£ gene therapy is absolutely ethical. **********.* ••• *.** ••• *****.***.*.** ••• *.** •• *************** Assume the position o£ one o£ the characters (i.e. a Lindrix student or parent in £avor o£ the gene therapyp a Lindrix student or parent against the gene therapyp a Lindrix administrator p a representative from one of the coapeting universities p the director o£ Lindrix's job place.ent prograa p etc.) involved in the above case study. Identify the major ethical dile.aas that your character faces p and determine how you would act in such a situation. Support your stance with ethical principles and "I" values. 70 Case Study: Human Genome Project (HGP) The year is 2015 A.D., and the Human Genome Project <HGP) has been completed. Knowledge gained froa the HGP has revealed that a certain subpopulation of "Race A" possesses alleles of the genes for intelligence that are "genetically superior" to those of other races or subpopulations. Persons of this subpopulation usually demonstrate greater levels of intelligence than persons of other races or subpopulations and are thus predicted--and even expected--to be aore successful, especially in areas of life which rely heavily on cognitive abilities. The discovery of this racial, genetic "predisposition" for high intelligence is having profound social, cultural, educational, and economic effects on society. After the knowledge of racial differences in intelligence was disclosed, schools and universities began changing their methods of operation. Many of the teachers at the primary and secondary levels now "cater" to their students who are of the "Race A" subpopulation presumed to have superior intelligence. Several have adopted the attitude that because these students are genetically predisposed to have high intelligence, they are capable of accomplishing much more than students who are not of this I ! t subpopulation. As a result, .any special and advanced programs, designed specifically for students with the "genetically superior" intelligence, are added to the curriculums. Often, they are done so at the expense of the rest of the students, as the new programs tend to take up more and more of the teachers' time and efforts. Universities have also changed in response to this new knowledge, altering their criteria for admission and for the granting of scholarships. In addition to SAT scores and grade-point-averages, race is now looked at closely by officials when reviewing applications and awarding scholarships. Some universities have even set quotas, admitting a higher percent of students of the superior '"Race A" subpopulation than of any other race or subpopulation, as a result of this knowledge. Also feeling the impact of this new knowledge is the occupational world. Discrimination is rampant, as most employers (understandably> seek to hire employees of the superior "Race A" subpopulation, especially in the fields of science and engineering. Furthermore, many employers have begun to offer prospective employees of the superior "Race A" sub-population higher starting salaries and better benefits than they normally offer. This is done primarily to compete with other employers in trying to attract the best new prospective employees. Starting salaries and benefits for prospective employees of other races see no such change, however. • 72 J I t Another potential effect of the knowledge of racial differences in intelligence concerns the issue of population control. Some leading experts on this topic have proposed that once population control is inevitable, persons who are not of the superior "Race A" subpopulation should be the first to be limited with respect to the number of chiloren they are permitted to have. If everyone must eventually be limited, then those in the superior subpopulation of "Race A" should be limited proportionately less. These experts give the rationale that since high intelligence is an extremely beneficial asset, we should, when forced, limit our population in a way that will increase the proportion of people who will fall into this category. Finally, this new knowledge is having a draMatic cultural effect. As opposed to being discouraged and denounced, interracial marriages are now seen more favorably. The possibility of infiltrating the alleles for superior intelligence into all races via the offspring of interracial marriages makes this previous cultural taboo more attractive and acceptable. In fact, it is even becoming desirable, and therefore encouraged, by some! Thus, members of society are challenged to adjust to a dramatically changing culture . •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Directions: After reading this case study, identify the ethical issues and select what you believe to be the major 73 ethical proble.. Propose several solutions for all proble.s and decide which one you feel is the .ost ethically defensible for each. Be prepared to support your opinion wi th eth ical principles and "I" values. Attempt to reach a consensus on both the Major ethical problem and its most ethically defensible solution in a discussion group. 74 Case study: Human Genome Project (HGP) and Mental Health By Linda K. Bevington and Jon R. Hendrix The year is 2012 A.D., and information obtained from the now completed Human Genome Project (HGP) ing society. is dramatically affect- Several mental illneses, such as schizophrenia, certain forms of depression, and a host of neuroses, are now known to have a genetic basis, and this knowledge is greatly impacting the mental health field. Mental hospital administrat- ors and psychological counselors now commonly require routine screening of potential patients and clients who are suspected to have any of these conditions to determine if they are caused by genetic factors. Often, those patients and clients who are found to be genetically predisposed to mental illnesses are treated differently than those whose conditions are not genetic. For instance, they are commonly encouraged to undergo gene therapy as the method of treatment for their illnesses. Most insurance companies are willing to pay for this therapy, so the cost of treatment is not a hindrance to these patients and clients. Nevertheless, some still object to gene therapy due to religious beliefs or personal values. In response to this unwillingness to undergo gene therapy, many hospital staffs refuse to admit these patients, justifying their actions with reasons of overcrowding or staff shortages. 75 Many counselors also refuse to see clients who are genetically predisposed to mental illnesses; others agree to counsel them, but raise their fees. Most insurance com- panies also raise their rates for, or even deny assistance to, these patients and clients. The rationale usually given for these actions is the poor prognosis for recovery which typically is the case for patients and clients whose mental illnesses are due to genetic factors. Besides gene therapy, no drugs or other forms of extrinsic therapy that have more than minimal, short-term treatment success have been developed to treat these conditions. Therefore, counselors feel that their time spent in sessions with these people will probably not be productive and that these clients, as a result, are likely to terminate treatment prematurely. Because premature termination of treatment results in the breaking of the client-counselor contract, the ~ounselor ends up losing money. Thus, many feel compelled to charge these clients more initially as a financial safeguard. Another justification commonly given for the denial or increased cost of treatment to patients and clients whose illnesses are genetic is the premise that, because these patients and clients are unwilling to undergo gene therapy, they lack the motivation to recover from their illnesses which would be necessary in any treatment method. An extreme outcome of the knowledge that some mental illnesses are due to genetic factors is the proposal that patients and clients who suffer from severe, "dangerous" mental afflictions (and who are thus a potential threat to society), but who do not receive treatment as a result of their refusal to undergo gene therapy, should be sent directly to prison! 76 Advocates of this proposal maintain that patients and clients who refuse to undergo treatment which would likely reduce the risk of danger to society can, after all, be thought of as criminal. ************************************************************** Directions: Assume the role of either a patient or client with a genetic predisposition toward mental illness or of a hospital administrator or psychological counselor. What argu- ments would you use in presenting your side or position? How might a patient or client challenge the ethics of the administrator's or counselor's actions? How could the administrator or counselor justify his or her actions? Be prepared to sup- port your position in a discussion group format. Copyright, Feb. 1992, Jon R. Hendrix and Linda K. Bevington Additional Questions: 1. 2. 3. 4. 5. How would society be affected by the differential treatment of patients/clients genetically predisposed to mental illnesses? How would the patients/clients themselves be affected? What implications would the above scenario have on the criminal justice system? on the field of psychology? on the counseling profession? Is coercion of patients/clients genetically predisposed to mental illnesses ethical? Does such coercion infringe upon their rights? Should a counselor have the right to refuse to see, or raise the rates for, patients/clients genetically predisposed to mental illnesses? In the above case, whose interest should be considered first, society's or the individual's? Appendix C 78 Seat No. Copyright, (c) Apri I, 1980 Jon R. Hendrix Name _____________________ BIOETHICAL VALUE-CLARIFYING, DECISION-MAKING MODEL RESPONSE SHEET I. Identify problem. Must be a problem that conflicts with at least two of your values or ethical principles and pul Is you in two directions. State problem as an ought to do question (e.g, 'what ought I do when ....• ) (a) Write a short paragraph on why you have Identified your problem as a value/ethical conflict for you. (b> Use the '1 Value Sheet· attached or a narratIve of your values and identify and list five (5) personal values you hold that are expressed in your problem paragraph statement. Ran1dng (c) 1. 2. 3. 4. 5. = most important to you to 15 = least (c) Rank these values from 11 to you. important (d) Are values numbered 1 and 2 above In conflict when you explore your problem. Yes_ _ No_ 79 2 II. List as many alternative solutions to the problem as you can, even if some do not agree with your values or principles (minimum of 5). Solutions Ranking 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. III. Rank your alternative solutions from the ~ (#1) your values agree with most to the ~ (I?) your values agree with least. <Use ranking column beside part II.) IV. Take your #1 solution and list the VALUES/PRINCIPLES you hold that cause you to rank it #1. #1 solution (state it): Values or principles you hold that support this solution: Please try to explore at least 8 values. I Value 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Personal M~3ning of Value Word 80 3 V. Take the solution you agree with ~ (ranked last) and list those VALUES/ PRINCIPLES you hold that cause you to rank it last. Last solution (state it): Values or principles you hold that cause you to reject this solution. try to explore at least 8 values. I Value Personal Meaning of Value Word Please 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. VI. For your #1 ranking, list as many probable CONSEQUENCES you can imagine if that solution ~ere implemented world-wide. Be sure to include consequences that affect such systems as: home. family. business. government. professions. economics. psychology. medicine. Ja~. and theology. Consequence AsseSsment System CQDsequeDce 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Appendix E 87 Raw Data College Discussion Group (H-22) Questions 1-8 Student I Number correct Number correct on pretest on post-test 1 2 6 2 6 7 3 3 7 4 5 8 5 4 7 6 2 6 7 2 5 8 1 7 9 5 6 10 1 6 11 0 5 12 2 4 13 2 6 14 3 7 15 1 6 16 1 7 17 3 4 88 Raw Data: College Discussion Group Questions 1-8 (Continued) Student # Number correct on pretest Number correct on post-test 18 1 5 19 3 7 20 1 7 21 3 3 22 5 7 1 89 Raw Data: College Discussion Group Question 9 Answers for part one and part two of the following questions are given consecutively under the headings "pretest" and "post-test." 9. Student # Pretest Post-test 1 B,B B,- 2 BIB B,D 3 CIC BIC 4 BIB BID 5 C,C BIC 6 C,B B,C 7 BIC B,D 8 CIC CIC 9 BIC B,D 10 B.D B,D 11 CIC B,C 12 C,A BIC 13 BIC B.D 14 CIC BID Raw Data: College Discussion Group Question 9 (Continued) Pretest Post-test 15 BtC BtB 16 CtC BtC 17 BtC BtD 18 DtA BtC 19 BtC BtC 20 DtA BtC 21 BtC BtC 22 AtD AlA Pretest Post-test 1 CIA BI - 2 CIB BID 3 CtA BIB 4 CIA CtA 5 CIA CtB 6 CIB CIA 7 BIB BIB Student # 10. Student # 91 8 C,A C,A 9 C,A C,A 10 C,A C,A 11 C,C C,A 12 C,B CIA 13 CIB C.A 14 B,B B,B 15 B,B B,B 16 C,A C,A 17 B,B B,C 18 C,B CIA 19 C,B CIA 20 B,C C,B 21 C,A C,A 22 C,A A.A Pretest Post-test 1 B,C C,D 2 C,A C.D 3 A,C B,C 4 A,C C,C 5 D,B B,B 6 B,C B.C 7 A,B B,C 11. Student # ., 92 Raw Data: College Discussion Group Question 11 (Continued) Student. Pretest Post-test 8 B,C B,C 9 C,c BtC 10 AtC B.C 11 B.B B.A 12 BtB B.C 13 A.B C.D 14 B.B C.C 15 BtB CtB 16 C.C C.D 17 B.B C.B 18 C.B B.C 19 CtB C.C 20 D.D B.D 21 B.B B.C 22 C.B D.B Pretest Post-test D.C C.D 12. Student • 1 93 Raw Data: College Discussion Group Question 12 (Continued) Pretest Post-test 2 AID CID 3 BIB AlB 4 CtA CtB 5 AtC AtB 6 AtB AtB 7 BtC AlB 8 AtB AIC 9 BtB A,B 10 B,B A,B 11 A,B A,B 12 AlB AlB 13 A,B D,B 14 AtC A,B 15 AlB BIB 16 DIB DIC 17 AlB A,B 18 DIC AlB 19 B,C DIB 20 DtD CIA 21 B,B A,B 22 C,B D,D Student I , 94 1 ! Raw Data: College Discussion Group Question 13 13. Student # Pretest Post-test 1 B.C A.D 2 BIB CIC 3 BIC AIC 4 BID BID 5 B.C BIB 6 BIC BIB 7 AlB B.C 8 BIC BIC 9 CIC B.C 10 AIC AIC 11 BIC BIC 12 B,C BIC 13 BIC BIC 14 C.B C.C 15 B,B CIB 16 CIC BIC 17 BIB C,B 18 CIB BIC 19 CIB CIC 20 D,D B,B , 95 t 1 Raw Data: College Discussion Group Question 13 (Continued) 21 B.B B.C 22 B.B B.B Raw Data: College Discussion Group Question 14 Answers for part one, part two, part three, and part four are given consecutively under the headings ·pretest" and "post-test." 14. Pretest Post-test 1 A,A.A,- B,A.B.A 2 B.B.B.B A.B.A.B 3 A.A.-.B A.A.A.B 4 A.A.B.B A.-.A.B 5 A.A.A.B A.A.A.B 6 A.B.A.B A.A.A.B 7 A.A.A.B A.A.A.C 8 A.B.A.B A.A.A.B Student • 9 A,B,-,D A,B,A,B 96 Raw Data: College Discussion Group Question 14 (Continued) 10 B,A,B,B B,A,B,B 11 A,A,A,C A,A,A,B 12 B,B,B,- A,A,A,B 13 A,B,B,C B,A,B,B 14 A,B,A,B A,A,A,B 15 A,A,A,B B,A,B,- 16 B,A,B,A B,B,B,A 17 -,A-,A -.A.-.A 18 A.B,A.D B.B.B.B 19 B,A,B,C A.A.A.B 20 B.A.B.A B.A.B.B 21 A.A,A.B A,A,A,B 22 B,A.B,B B.A,B,B The answers to part one and part two of the following question are given consecutively under the headings "pretest" and "post-test." 15. Student t 1 2 Pretest Post-test B.C B.A B,D B,D 97 Raw Datal College Discussion Group Question 15 (Continued) 3 A,C A,C 4 B,D B,C 5 A,C A,D 6 B,B B,B 7 B,C A,D 8 BIC AIC 9 AIC B,D 10 BIC BIC 11 AlB B,C 12 BIB A,C 13 B,A BID 14 AlB BID 15 -I- B,A 16 BIC AIC 17 BIA BIB 18 BIA BIC 19 BIC BIC 20 BI - BIC 21 AlA AIC 22 B,B BIB 98 16. Pretest Post-test 1 B B 2 B B 3 B B 4 B B 5 B B 6 B B 7 B B 8 B B 9 B B 10 B B 11 B B 12 B B 13 B B 14 B B 15 B B 16 B B 17 B B 18 B B 19 B B 20 B B 21 A B 22 B B Student_# 99 17. Student # Pretest Post-test 1 B B 2 B B 3 B A 4 B B 5 B B 6 B' B 7 B B 8 B B 9 B B 10 B B 11 B 12 B B 13 B B 14 B 15 B B 16 B B ]7 B B 18 B B 19 B B 20 B B 21 B B 22 B B ~ l ~ 100 ,"i.: 18. Student # Pretest Post-test 1 A A 2 A A 3 A A 4 B A 5 B A 6 A A 7 A A 8 B A 9 A A 10 A A 11 A 12 A A 13 A A 14 A A 15 A A 16 A A 17 A A 18 A A 19 A A 20 A A 21 B A 22 A A ) Appendix F 102 Raw Data High School Discussion Group (N-14) Questions 1-8 Student # Pretest Post-test 1 2 6 2 4 5 3 5 4 4 2 3 5 5 7 6 3 4 7 3 6 8 3 4 9 3 4 10 1 3 11 1 3 12 3 2 13 4 5 14 4 1 103 Raw Data: High School Discussion Group Question 9 Pretest Post-test 1 At A BtC 2 BtD CtC 3 CtD CtA 4 -t A Ct - S Bt - BtD 6 BtC BtD 7 BtD BtD 8 CtB BtD 9 AtD BtD 10 BtC BtD 11 BtC BtD 12 CtA BtD 13 CtB CtC 14 CtA CtD Pretest Post-test 1 BtC CtA 2 CtA CtA 3 At A BtA Student # 10. Student # 4 -,e D,- , 104 I Raw Data: High School Discussion Group Question 10 (Continued) Student , Pretest Post-test S C.A C.A 6 C.B C.D 7 C.C C.A 8 B.A C.A 9 C.D C.A 10 C.A C.A 11 C.B C.A 12 B.C C.A 13 B.A C.A 14 B.C C.A 11. Student , Pretest Post-test 1 B.B C.C 2 B.B B.C 3 B.A B.D 4 -.A D.- S A.D C.D 6 D.A D.A B, -A BIB 7 105 Raw Data: High School Discussion Group Question 11 (Continued) Pretest Post-test 8 e.A D.B 9 D.A A.e 10 D.B e.e 11 D.B e.e 12 B.A B.e 13 D.A B.e 14 e.A B.e Pretest Post-test 1 A.e D.e 2 A.B e.B 3 A.A A.A 4 -.e D.- S A.- D.A 6 e.D A.D 7 e.D A.B 8 -.e e.D 9 D,A B,D Student t 12. Student t 106 Raw Data: High School Discussion Group Question 12 (Continued) Pretest Post-test 10 CoB A.B 11 A,B C.C 12 A,D A.C 13 D.C D.D 14 B.D C.B Pretest Post-test 1 B.B B.B 2 B.B B.D 3 B.A B.D 4 - .A A, - 5 A.D C.D 6 B.A B.C 7 B.A B.A 8 -.A D.C 9 D.A A.D 10 B.C CoB 11 B.C B,A 12 B,C A,B Student • 13. Student • I! 107 Raw Data: College Discussion Group Question 13 (Continued) 13. Pretest Post-test 13 B.A D.B 14 B.A e.B Pretest Post-test 1 A.A.B.e A.B.A.B 2 A.A.A.B A.A.A.B 3 A.A.A.A A.A.A.A 4 -.-.-.D B.A.-.- S B.A.B.A B.B.B.A 6 A.A.A.A A.A.A.A 7 A,B.A,B A.A,A,B 8 A,A,A,D B.-.-,A 9 A.A,A.D B.A.A.A 10 B,A,B,B A.B,A.A 11 A.A.A.A A.A,A.B 12 A,A.A,D B.A,B,A 13 B,B.B.B B,B,B,B Student # 14. Student I 108 1 , . Raw Data: High School Discussion Group Question 14 (Continued) Pretest Post-test B.-.-.D A.B.A.B Pretest Post-test 1 A.B A.B 2 A.B A.D 3 A.A A.A 4 -.B A.- 5 B.D A.D 6 B.A B.D 7 B.C B.A 8 A.D B.D 9 B.A B.D 10 B.C A.C 11 A.A A.D 12 B.C B.D 13 A.C A.D 14 A,A A,-D Student • 14 15. Student • , 109 , ! 16. Student # Pretest 1 Post-test B 2 A A 3 A A 4 A B 5 B B 6 A B 7 B B 8 B 9 A B 10 B B 11 B B 12 B B 13 B B 14 B B Pretest Post-test 17. Student # 1 B 2 B B 3 A A 4 A B 110 Raw Data: High School Discussion Group Question 17 (Continued) Student • Pretest Post-test 5 B B 6 B A 7 B B 8 B B 9 B B 10 B B 11 B B 12 B B 13 B B 14 B B Pretest Post-test 1 B A 2 A A 3 B B 4 B A 5 A A 18. Student • III Raw Data: High School Discussion Group Question 18 (Continued) Student , Pretest Post-test 6 A A 7 A A 8 B A 9 B A 10 A A 11 B B 12 A A 13 B B 14 A A 1 112: •1 Raw Data High School Decision-Making Model (N a 21) Questions 1-8 Student I Nuaber correct Number correct on pretest on post-test 1 4 4 2 4 4 3 3 5 4 1 2 5 4 6 6 3 4 7 3 5 8 3 5 9 2 5 10 2 3 11 5 5 12 2 3 13 5 7 14 2 6 15 5 6 16 4" 8 I 113 Raw Data: High School Decision-Making Model Questions 1-8 (Continued) Student # Number correct Number correct on pretest on post-test 17 3 2 18 2 2 19 5 1 20 5 5 21 3 5 9. Student , Pretest Post-test 1 BtC BtC 2 CtC CtC 3 BtC BtD 4 CtB BtA 5 BtC CtC 6 S.C C.C 7 C.A C~C 8 CtD C.A 9 B,D B,D 10 B,B C,B , 114 • 9 B.D B.D 10 B.B CtB 11 C.B BtD Raw Data: High School Decision-Making Model Question 9 (Continued) Student I Pretest Post-test 11 C,B " I""" B,D 12 A.A BtC 13 - •- B.D 14 B.C B.D 15 C.A B.C 16 B.D B,D 17 C.A CtC 18 B.- C,B 19 A,A C.D 20 C,- C,C 21 C.B B.D 10. Student # Pretest Post-test 1 C.D C,A 2 B,C C,C 3 B,B C,A 4 C,B C,A 115 B.B Raw Data: e.A High School .Decision-.Making Model Question 10 (eontinued) Student # Pretest Post-test 5 B,B C,A 6 e.D e.A 7 B.e e.A 8 B.A e.A 9 e.A e.D 10 B.B e.- 11 e.B e.A 12 e.D etA 13 etB e.e 14 etB etB 15 e.A etA 16 etA C.B 17 e.A etA 18 -.B BtA 19 etA etA 20 AtD B.B 21 etB etA 1 116 , 11. Pretest Post-test 1 BIB BtC 2 Ale BtC 3 BIA BIC 4 BtB DIB 5 BtC BtC 6 BIC BIC 7 etA BIC 8 DtC DtB 9 BtC BtC 10 BIB BIB 11 BtB BID 12 DIA BIB 13 BIB BIC 14 BIB BIC 15 BIC D.C 16 etA BtB 17 AlA DIB 18 Bt - BIA 19 BtA BIB 20 AtB CIB 21 A,B B,D Student • 117 12. Pretest Post-test 1 D.D e.D 2 A.B e.B 3 A.D A.A 4 A.D e.B 5 A.B A.B 6 A.e A.B 7 A.e A,B 8 B.A C.B 9 A.e A,e 10 A.e A,B 11 D.B B,e 12 A,D A,A 13 A,B A,B 14 A,B A,B 15 A,B e.B 16 A,B A,e 17 B,D A,e 18 B,- A,A 19 A,D A,e 20 A,B B,B Student # 21 B,D A,A , 118 I 13. Student # Pretest Post-test 1 A.A B.e 2 B.e B.e 3 D.A B.e 4 B.A D.B 5 B.e B.e 6 D.e B.D 7 B.B B.e 8 e.B D.A 9 B.e B.D 10 B.B B.B 11 A.A e.e 12 e.A D.e 13 B.B B.e 14 B.B B.A 15 B.B B.e 16 B.B A.e 17 A.A B.B 18 B.- A.A 19 A.A B.B 20 A.B e.B 21 A,A B,D 119 14. Student # Pretest Post-test 1 -.-.A.A B.B.B.B 2 A.A.A.e A.B.A.B 3 A.B.A.e B.A.B.e 4 A.A.A.e B.A.B.A 5 A.A.A.B A.A.A.B 6 A.A,A,B A,B,A,A 7 A,A,A,e A,-,A,B 8 A,A,A,A B,A,B,B 9 B,A,B,A B,A,B,e 10 A,-,A,B -,A,-,B 11 B,A,B,B -,A,-,e 12 B,A,B,D B,A,B,A 13 A,A,A,e A,B,A,B 14 A,B,A,B -,-,-,B 15 A,A,B,B B,A,B,A 16 A,A,A,B A,A,A,B 17 A,A,A,B A,A.A,B 18 -,B,-.- A,A.A,B 19 A,B,A,e A,B,A,B 20 A,A,A,B B,A,B,B 21 A,B,A,B A,A,A,B 120 A.B.A,B A.A.A.B Pretest Post-test 1 B.C B.D 2 A.C A.A 3 A.A A.D 4 A.D B.A 5 A.A B,C 6 A.D A.B 7 B.B B,D 8 B.D B.A 9 B.D B,D 10 A,B B,B 11 B.A A,D 12 B,C A,C 13 A.C B,D 14 B,C B,D 15 A,D B.D 16 B.D B.D 17 A.C A,e 18 -.B A.C 19 A.D A.D 20 A.D A,A 21 A,D B,C 21 15. Student # 121 16. Pretest Post-test 1 B B 2 B B 3 B B 4 A B 5 A B 6 B B 7 B B 8 A B 9 B B 10 A A 11 B A 12 B B 13 A B 14 A A 15 B B 16 B B 17 A B 18 B B 19 A A 20 A A B B Student # 21 122 17. Pretest Post-test 1 B B 2 B B 3 B B 4 B B 5 B B 6 B B 7 B B 8 B B 9 B B 10 B B 11 B B 12 B B 13 B B 14 B B 15 B B 16 B B 17 A B 18 B A 19 B B 20 A B 21 B B Student t 123 18. Pretest Post-test 1 A A 2 A A 3 A A 4 B A 5 B B 6 B A 7 B B 8 A A 9 A A 10 A B 11 A A 12 A A 13 A A 14 B B 15 A A 16 A A 17 A A 18 B A 19 B A 20 B A 21 A A Student #