1/26/2016 Our Consciousness Varies in: Consciousness: Awareness of one’s own mental activity (sensations, feelings & thoughts) and of the external world Not just 1 type of consciousness, but a “continuum” of different levels, from extreme alertness to the deepest coma. Biorhythms • Regular, periodic fluctuations in biological & psychological functioning • Most common: circadian rhythms - 24 hr cycles • Regulated by biological clock in the suprachiasmatic nucleus (SCN) of hypothalamus (Concept Organizer 5.1) • This clock is set/reset by the day/night cycle – mostly by morning light • http://www.youtube.com/watch?v=aF24ZmPwzb0 Other Circadian Rhythm Problems • Shift work where work hours conflict with built-in biological rhythms • Travel across time zones – biological clock out of synch with new location • SCN adjusts to later schedules (moving to a later shift or traveling to a later time zone) better than an earlier schedule • Morning light of new time zone re-sets SCN. Must control light exposure to adjust to shiftwork. • Focus (external vs internal; what we have selected to attend to) • Inattentional “blindness” (or deafness) – with focused attention on one thing we may be blind to or unaware of other input • Level of awareness required by different tasks (controlled vs automatic processes) Suprachiasmatic Nucleus (SCN) The clock tells the Pineal Gland when to secrete melatonin to make us sleepy. Most adults – 10 pm Teens – 1 am BUT: our modern day lights, computer screens, TVs, and even glowing LED displays can confuse the clock into thinking it is not yet night time. Seasonal Affective Disorder (SAD) or Winter Depression https://www.youtube.com/watch?v=lld7lFZm-m0 Note: 1st 6 symptoms resemble what we see in animals preparing to hibernate – perhaps SAD was a functional way to cope with winter in pour ancient past 1 1/26/2016 SAD associated with shorter days Seasonal Affective Disorder • http://www.webmd.com/depression/video/season al-affective-disorder-one-womans-struggle Sleep Lab or Sleep Clinic • Monitor: • EEG (brain waves) • EOG (eye movements) • EMG (muscle tension) Sleep EEG These 2 deepest stages are often lumped together into a single stage. “slow waves” 2 1/26/2016 A Typical Night’s Sleep 2 Main Types of Sleep • NREM (about 80% of night) • REM or Dream Sleep (20% of night) Characteristics of NREM Sleep • gradual decrease in movements, breathing, heart rate • slow, rhythmical brain waves (“delta waves”) • hard to wake up • If awakened you’re likely to say you were thinking. Only rarely (10%) do you dream in non–REM. NREM Sleep “Disorders” • Tend to run in families • Very common in kids. Most outgrow them- only a few adults continue to experience some episodes of NREM disorders. • Sleep-walking (17% of kids (peaking at 8-12 yrs), 4% of adults) • Night terrors (3% of kids, mostly < 6 yrs) • Bed-wetting (enuresis) REM Sleep • very active brain waves similar to waking • total loss of tone in most muscles • rapid jerky eye movements (REMs) • breathing, heart rate unpredictable • 80-90% chance of vivid dream report • erections; vaginal lubrication; regardless of dream content REM Sleep Disorders • Much more rare than NREM problems • Narcolepsy - REM sleep “attacks” with cataplexy, muscle paralysis, & hypnagogic hallucinations. Often triggered by emotion. • Animal Model of narcolepsy allows research Several meds can decrease sleep attacks of narcolepsy: -stimulants like Ritalin or amphetamine -somewhat safer Provigil - or by deepening sleep at night with Xyrem 3 1/26/2016 REM Behavior Disorder • REM behavior disorder - failure of the usual muscle paralysis mechanism of REM so the person can move during dreaming • Unlike narcolepsy, REM behavior disorder usually occurs in older individuals • May be associated brain damage/neurological disease like Parkinson’s disease • May be triggered by drug use in some Other Sleep Problems • Insomnia (over 60 varieties/causes) • OTC sleeping pills contain antihistamine (diphenhydramine) • Prescription • Benzodiazepines- (Xanax, Dalmane, Restoril) • Non-benzodiazepines (Ambien, Lunesta, Sonata,) • Over-the-counter – antihistamines • Sleep Apnea • CPAP • Mouthpiece that adjusts jaw position • Tonsillectomy in kids • Treatment – medications that decrease REM Effect of sleep deprivation on brain activation (math) Insufficient Sleep Associated With: • Drowsiness; unintended sleep • Increased irritability, anxiety, depression • Decreased socialization & sense of humor • Decreased cognitive & athletic performance • Decreased concentration, memory, problem-solving, creativity, decision-making • Decreased quality of work & productivity • Decreased health • Driving sleepy is as dangerous as driving drunk!! 1 in 6 single driver fatal crashes is due to falling asleep at the wheel! Theories Why We Sleep Norm al Sleep Dep. Adaptation/Protection Theory Cross-species Comparisons of Daily Hours of Sleep • Repair/Restore Theory: sleep allows the body to repair & replenish itself . During non–REM sleep growth hormone is secreted, the immune system is more active, and energy reserves are restored • Adaptation/ Protection Theory: sleep evolved because it conserved energy at a time that you couldn’t hunt for food & helped avoid harm during the more dangerous time of day, thus had survival value. • But do these theories fit those that sleep the most (fetuses & infants)? 4 1/26/2016 Both Total Sleep & REM Sleep Over Lifespan Are Longest During Early Development • Growth/Development Theory – Sleep (especially NREM) is for growth & development of brain • Learning/Memory Theory – Sleep (especially REM) is needed for memory storage & maintenance Sleep theories are not mutually exclusive – there’s data to support all of them Total Sleep Over Lifespan Alternative Theories of REM Sleep Function • Psychoanalytic/Freudian : dreams are a safe outlet for unconscious impulses or wish fulfillment • Biological/Activation synthesis theory: dreams are the brain’s attempt to make sense of the random activation of brain cells during sleep • REM sleep provides necessary activation of brain neurons during sleep • Cognitive - REM sleep is another informationprocessing time, helping us organize and interpret waking thoughts and experiences. Most dreams are about everyday events. 5