HEALTHCARE SECTOR PORTFOLIO COMPARISON SIM Weight S&P500 Weight Materials 4% Telecom Utilities 3% 3% Consumer Discretionary 11% Consumer Staples 11% Overview Energy 12% Health Care 12% Business Analysis Consumer Utilities Discretionary 3% 8% Consumer Staples 12% Information Technology 22% Industrials 10% Information Technology 19% Industrials 11% Materials 3% Telecom 4% Energy 11% Health Care 14% Financials 13% Financials 14% Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR Market Cap P/E ROE Dividend Yield LT D/E P/B Net Profit Margin P/FCF % of S&P500 Overview 41874.5 20.92 16.05% 3.72% 70.38% 17.58% 15.85% -60.23% 12% Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR INDUSTRIES Biotechnology Diagnostic Substances Drug Delivery Drug Manufacturers - Major Drug Manufacturers - Other Drug Related Products Drugs - Generic Health Care Plans Home Health Care Hospitals Long-Term Care Facilities Medical Appliances & Equipment Medical Instruments & Supplies 87% Medical Laboratories & Research Medical Practitioners Specialized Health Services Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion LARGEST COMPANIES IN HEALTHCARE Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR PERFORMANCE 1Yr 6mo QTD Returns 12.5% 14.1% 2.7% Monthly High Monthly Low Current P/E (fwd) 17.9 10.0 12.1 P/E (trailing) Overview Business Analysis P/B 4.1 2.2 2.6 Margin (EBITDA) 16.9 16.3 16.5 P/B Economic Analysis Financial Analysis Valuation Conclusion PORTER’S 5 FORCES Threat of New Competition Threat of Substitutes •FDA Approvals pose Barrier to Entry and Early Visibility of New Competitors. •Use of Generic medication is rising. •Numerous patents are expiring. Bargaining Power of Customers •Age Demographics are Growing •Political Forces are Targeting Heath-care. Bargaining Power of Suppliers •Specialized Ingredients with Few Substitutes •Often only one use for the raw materials. Intensity of Competitive Rivalry •Numerous companies bloomed in this sector. •Fierce competition for new medications. Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion EXTERNAL FACTORS • Average age of Patients are Increasing. • Patents • Patent Rights Uncertainty – Many of the companies in this sector have large revenue streams from patented medications. To minimize healthcare costs, early termination of patents has been discussed as a viable option to reduce healthcare costs. • Common / Preferred Generics - As soon as a patent expires, a low-cost provider readily supplies an alternative causing rapid drops in revenue. • Regulatory Pressure • Healthcare is a hot political topic . As the demographics grow the need for low cost healthcare is fueling market adjustments. • FDA – New pharmaceuticals must be clinically tested and approved. This process is becoming more stringent. Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion PATENT EXPIRATIONS Originating Company Pfizer GlaxoSmithKline Eli Lilly Sepracor Pfizer Sepracor Sankyo Abbott GlaxoSmithKline Merck Amgen Johnson & Johnson Overview Business Analysis Pharmaceutical Viagra Cialis Cymbalta Lunesta Detrol Xopenex Benicar Zemplar Lotronex Singulair Enbrel Cypher Economic Analysis Financial Analysis Expiration 3/27/12 11/21/17 6/11/13 2/14/14 3/25/12 3/25/13 4/25/16 4/17/12 1/13/13 2/3/12 10/23/13 11/06/13 Valuation Conclusion PHARMACEUTICALS PENDING FDA APPROVAL • All companies mention significant product development pipelines. • Phase 3 or Later • JNJ – 16 Pending Registration • Amgen – 10 Pending Registration • Pfizer – 14 Pending Registration • Phase 1&2, ~45 per company. • Annual Reports Show strong investments in R&D with Promising data Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR LIFECYCLE Healthcare Sector Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion US POPULATION PROJECTIONS - AGE 200,000 180,000 160,000 140,000 120,000 .100 years and over .85 years and over 100,000 .65 years and over .45 to 64 years 80,000 60,000 Data from US Census Bureau 40,000 20,000 0 2010 Overview 2015 2020 Business Analysis 2025 2030 Economic Analysis 2035 2040 Financial Analysis 2045 2050 Valuation Conclusion REAL GDP AND HEALTHCARE SECTOR Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion CONSUMER FOOD SPEND AND HEALTHCARE Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion EARNINGS OUTLOOK Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR P/E + PROJECTION Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion MARGINS & CASH Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion SECTOR LEADERS & FINANCES Industry Market Cap PEG Ratio P/B Profit Margin Operating Margin Johnson & Johnson (JNJ) DM - Major 176.23B 2.15 2.88 14.87% 24.84% Novartis AG (NVS) DM - Major 134.51B 2.48 2.06 15.35% 21.49% Pfizer (PFE) DM - Major 161.81B 3.27 1.81 14.85% 29.32% GlaxoSmithKline (GSK) DM - Major 134.51B 2.48 2.06 15.35% 21.49% Merck & Company (MRK) DM - Major 115.55B 2.77 2.11 13.05% 20.77% Sanofi – Aventis (SNY) DM - Major 99.94B 6.56 1.44 14.49% 20.89% Abbott Laboratories (ABT) DM - Major 85.85B 1.30 3.50 12.17% 20.40% AstraZeneca (AZN) DM - Major 60.93B 4.35 2.64 29.72% 38.78% Novo Nordisk (NVO) DM - Other 75.00B 1.71 11.28 25.77% 33.72% Biotechnology 52.62B 1.26 2.8 23.64% 33.96% Amgen (AMGN) Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR VALUATION Absolute Basis High Low Median Current P/Trailing E P/Forward E P/B P/S P/CF 28.4 25.6 7.5 3.1 22.2 9.9 10.0 2.2 1.0 7.6 18.2 17.2 3.8 1.8 13.4 12.4 12.0 2.6 1.2 9.2 High Low Median Current 1.2 1.2 2.4 2.1 1.7 0.68 0.69 1.1 0.9 0.9 1.0 1.0 1.4 1.2 1.3 0.94 0.92 1.20 1.00 1.00 Relative to SP500 P/Trailing E P/Forward E P/B P/S P/CF Median Current 5.8 5.2 1.2 0.6 4.2 Median Current 0.06 0.08 0.20 0.20 0.30 Overall, Healthcare looks cheap compared to historical values. We believe this is due to . . . Uncertainty surrounding regulations and increasing demands for low-cost healthcare from a growing demographic. Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion INDUSTRY VARIATION Industry variation is low with exception of the Diagnostic Substances and Medical Laboratories & Research industries. Recall Pharmaceuticals Dominates the Sector, its P/E is at the Mean. Industry Medical Practitioners Hospitals Diagnostic Substances Medical Laboratories & Research Overview Business Analysis Market Cap P/E ROE % 3.31B 7.6 319.8B 11.94B 131.43B 10.0 179.6 202.8 Economic Analysis P/B 45.04 Margin 5.6 P/FCF 12.7 D/E 5.92 144.0 2.5 1.5 76.39 36.47 75.61 -2.49 4.99 -9.45 4.3 2.7 0.8 489.9 134.7 -40.6 Financial Analysis Valuation 4.3 Conclusion • Healthcare saw massive growth after the surge of the pharmaceutical industry. TECHNICAL ANALYSIS: HEALTHCARE SECTOR • Currently the industry is more mature, has reached a sustained growth rate. • We foresee consolidation through mergers and acquisitions in the future. • In the long term, other industries within the Healthcare Sector will grow, displacing Pharmaceuticals as they do. Overview Business Analysis Economic Analysis Financial Analysis Valuation Conclusion HEALTHCARE SECTOR RECOMMENDATION Recommendation – Reduce Healthcare Sector by 200 BP to S&P Weighting. Current Weights: S&P -12%, SIM-14% Positives Risks • Big Problems Left • Cancer • Alzheimer's • Life Expectancy and Age Demographics are Growing • Legislation • Patents / Generics • Medicaid / Medicare • Don’t Expect Large Sector Growth Industries to Overweight • Generics • Hospitals • Medical Practitioners Overview Business Analysis Industries to Underweight •Diagnostic Substances •Medical Laboratories & Research Economic Analysis Financial Analysis Valuation Conclusion