Spring 2012 USC-Aiken ABIO 541 Principles of Biochemistry Syllabus PROFESSOR: Dr. C. Nathan Hancock OFFICE: Room 205, Science Building OFFICE HOURS: By appointment COURSE CREDIT: 3 Credit Hours PREREQUISITES: ACHM 332 and ABIO 121 or consent of instructor CLASS TIME: (200 SCI BLDG) M/W 2:30 to 3:45 CONTACT: 803-641-3390 nathanh@usca.edu TEXT: Fundamentals of Biochemistry: Life at the Molecular Level, 4th Edition Available as an e-book, loose leaf, or hardback 3rd edition may also be acceptable Please read this syllabus carefully and refer to it when you have questions about the course. COURSE DESCRIPTION AND OBJECTIVES: A survey of the fundamental principles of biochemistry. The topics covered include: cellular chemistry, amino acid structure and chemistry, protein structure, carbohydrate chemistry, enzyme kinetics and enzyme inhibition. Objectives: Describe the basic role of carbohydrates, lipids, nucleic acids and proteins Understand the relationship between chemical structure and biological function Explore the chemistry behind reactions occurring in living systems GRADE COMPONENTS: Two Midterm Exams Lecture quizzes and assignments Final exam 200 pts each 400 pts 200 pts (40% total) (40%) (20%) GRADING SCALE: 100-90% = A; 89-85% = B+; 84-80% = B; 79-75% = C+; 74-70% = C; 69-65% = D+; 64-60% = D; 59-0% = F. ATTENDANCE POLICY: “When students enroll in a particular course, they obligate themselves for all the work which may be assigned. Punctual and regular attendance is vital to the discharge of this obligation.” Though attendance will not be taken, you must be present to receive credit for in class assignments, and quizzes. There are also no make-up exams. Should you miss an exam for a documented excusable reason (i.e. sickness or required university event); an alternate exam may be arranged. Only one exam will be treated in this manner; any other missed exams will be counted as a zero. GRADING: The exams and assignments will require hand written answers. Answers will only be accepted if they are clearly legible. Graded materials will be returned in a reasonable time period. Spring 2012 TENTATIVE LECTURE SCHEDULE Spring 2012 Date Topic 9 Jan Introduction 11 Jan Water 16 Jan Martin Luther King Holiday 18 Jan Water 23 Jan Nucleotides, Nucleic Acids, and Genetic Information 25 Jan Nucleotides, Nucleic Acids, and Genetic Information 30 Jan Carbohydrates 1 Feb Carbohydrates 6 Feb Lipids and Biological Membranes 8 Feb Lipids and Biological Membranes 13 Feb Review 15 Feb 1st Exam 20 Feb Amino Acids 22 Feb Amino Acids 27 Feb Proteins: Primary Structure 29 Feb Proteins: Primary Structure 2 Mar Last day to withdraw or drop without a "WF” 5-9 March Spring Break 12 Mar Proteins: Three-Dimensional Structure 14 Mar Proteins: Three-Dimensional Structure 19 Mar Protein Function: 21 Mar Protein Function: 26 Mar Review 28 Mar 2nd Exam 2 Apr Enzyme Catalysis 4 Apr Enzyme Catalysis 9 Apr Enzyme Kinetics, Inhibition, and Control 11 Apr Enzyme Kinetics, Inhibition, and Control 16 Apr Biochemical Signaling 18 Apr Biochemical Signaling 23 Apr Review 2 May Final Exam (2pm) USC-Aiken ABIO 541 Chapter 1 2 2 3 3 8 8 9 9 1-3, 8-9 4 4 5 5 6 6 7 7 4-7 11 11 12 12 13 13 11-13 CLASSROOM BEHAVOIR AND PORTABLE ELECTRONIC DEVICES: It is the instructor’s right to remove any student who disrupts or disturbs the proceedings of the class. In extreme cases the professor can request assistance from the University police. If the student who has been ejected causes similar disturbances in subsequent meetings of the class, he/she may be denied admittance to the class for the remainder of the semester and assigned a grade of “F”. The use of any portable electronic devices, including cell phones, pagers, MP3 players, iPods, etc., during class is not allowed for any reason unless prior approval has been given to a student from the instructor or unless required for the course. If you are planning to have any of these devices in class, they must be turned off and stowed away for the duration of the class period. If you use a portable electronic device during a test, quiz, or other assessment, you are eligible to receive a failing grade on that assignment. Spring 2012 USC-Aiken ABIO 541 DISABILITY STATEMENT: If you have a physical, psychological, and/or learning disability which might affect your performance in this class, please contact the office of disability services, 126A B&E, (803) 641-3609, as soon as possible. The disability services office will determine appropriate accommodations based on medical documentation. WRITING CENTER: USCA provides a writing center located on room 201 of the H&SS building. If you need extra assistance on any writing assignment for this or any other class that you are taking, please try the writing center. HONOR CODE: Students are expected to abide by the Academic Code of Conduct as described in the Student Handbook. Appropriate disciplinary action will be taken if academic integrity is violated. The following honor pledge is to be written, signed, and dated by the student on all exams and assignments turned into the instructor. “On my honor as a University of South Carolina at Aiken student, I have neither given nor received any unauthorized aid on this assignment/ examination. To the best of my knowledge, I am not in violation of academic honesty.”