Statistics 402B April 8, 2011 Exam 2 Name: __________________________ INSTRUCTIONS: Read the questions carefully and completely. Answer the questions and show work in the space provided. Give appropriate units with all summary values. Credit will not be given if work is not shown. Be sure to answer all questions within the context of the problem. Refer to the computer printout and graphs provided when appropriate. If the computer printout has the answer use it, you do not have to do a hand calculation if it is already done for you by the computer. Pace yourself. Do not spend too much time on any one problem. Point values for each problem are given. 1. [25 pts] The text discusses an experiment to compare the effect of four different doses of insulin (A, B, C, and D) on the blood glucose level of rabbits. The blood glucose level (mg/dL) is measured 50 minutes after the injection with insulin. a. [1] What is the response? b. [1] What are the conditions? c. [1] What are the experimental units? d. [2] If we were going to conduct the experiment using a completely randomized design, how many rabbits would you need to detect a difference in dose means of 1.6 standard deviations with Alpha = Beta = 0.05? e. [4] Give two reasons why conducting the experiment as a block design (forming blocks by reusing rabbits) is better than a completely randomized design. 1 f. [4] Reusing rabbits creates a problem because it takes a day for the insulin dose to wear off before the next dose can be administered. Explain what the problem is and how a Latin Square design takes care of this problem. g. [3] A Latin Square experiment with rabbit and day as the two nuisance factors was randomized and run. Below are the dose sample means. Compute the estimated effect of each dose and indicate which dose(s) has(have) the biggest effect on blood sugar level. Dose Mean Blood Glucose Level A B C D 56.0 mg/dL 40.0 mg/dL 53.0 mg/dL 35.0 mg/dL Estimated Effect Below is the ANOVA table for the analysis of the blood sugar level data. Source Model Doses Day Rabbit Error C. Total df 9 3 3 3 6 15 Sum of Squares 2136.0 1224.0 504.0 408.0 214.0 2350.0 Mean Square 237.333 408.0 168.0 136.0 35.667 F – Ratio 6.654 11.439 4.710 3.813 Prob > F 0.0158 0.0068 0.0767 0.0510 h. [4] Test the hypothesis that the dose effects are zero against the alternative that some dose effects are not zero. 2 i. [5] The value of the Tukey-Kramer HSD is 14.62. If you wanted to get the lowest blood sugar value, which dose would you recommend? Support your answer statistically. 2. [25 pts] An experiment is conducted to explore the relationship between height of step (5.75 in or 11.5 in) and rate of stepping (14 steps/min, 21 steps/min or 28 steps/min) on the change of heart rate of college students. Six college students are used in the study. There are 6 combinations of step height and stepping rate. Each student experiences each combination. The order is randomized for each student and enough time separates the trials so that students’ heart rates return to a resting rate. The resting heart rate for each student is taken before each trial and the heart rate at the end of 3 minutes of the stepping combination is also measured. The change in heart rate is calculated by subtracting the resting heart rate from the heart rate after stepping. Refer to the JMP output for the “Stepping Experiment.” Note: There are several different analyses of the data in the JMP output, not all of which are correct. a) [4] What are the response, conditions of interest and experimental material? b) [4] What design was used to collect the data? Explain how you know what design was used. 3 c) [3] Are there statistically significant differences among the sample means for the step heights? Report the appropriate F-statistic, P-value, decision, reason for the decision and conclusion. d) [3] Are there statistically significant differences among the sample means for the stepping frequencies? Report the appropriate F-statistic, P-value, decision, reason for the decision and conclusion. e) [4] Comment on the interaction plot. Describe what you see in the plot and what it indicates about the possible interaction between step height and stepping frequency. f) [3] For comparing treatment (combination of height and frequency) means the value of q is 3.08179. Compute the value of HSD. 4 g) [4] What would your recommendation be if you wanted the largest average increase in heart rate? Support your answer statistically. 3. [20 pts] Name that design! For each of the following scenarios indicate what design is used. Indicate the response variable, factors of interest, whether factorial crossing is used to make treatments, nuisance factors and provide a partial ANOVA table listing all sources of variation and associated degrees of freedom. a. [7] A marketing firm sets up an experiment to see if coupons or mail-in rebates have an effect on unit sales of a product. In each store, there is a display with the product. The treatment combinations are: (1) no coupon and no rebate, (2) $1 coupon and no rebate, (3) no coupon and $1 rebate, (4) $1 coupon and $1 rebate. The marketing firm selects 10 stores at random. Each store will display the product under each of the treatment combinations for one week and record the unit sales. The order of the treatment conditions will be randomly assigned at each store. Design: Source df Factors: Is factorial crossing used? Nuisance variables: 5 b. [6] An experiment (field trial) is conducted to investigate the yield of corn using 5 different levels of nitrogen fertilizer. There is one variety of corn used throughout the experiment. The five levels of nitrogen are: 0 lbs/acre, 30 lbs/acre, 60 lbs/acre, 90 lbs/acre and 120 lbs/acre. To get a better picture of yield across the state, there are five locations that will be used in the experiment. At each location, there are five plots. Five plots are selected from the 25 plots (five plots at five locations) at random and assigned 0 lbs/acre. Five plots are selected from the remaining 20 plots at random and assigned 30 lbs/acre. Five plots are selected from the remaining 15 plots at random and assigned 60 lbs/acre. Five plots are selected from the remaining 10 plots at random and assigned 90 lbs/acre. The remaining five plots are assigned 120 lbs/acre. Design: Source df Factors: Is factorial crossing used? Nuisance variables: c. [7] An experiment is conducted to see the effect of brand of golf ball and brand of driver on the length a golf ball travels. There are three brands of golf ball: Calloway, Nike and Titleist. There are two brands of driver: TaylorMade and Cleveland Golf. Because driving skill and strength may vary from one golfer to the next, six different golfers will be used in the experiment. Because weather conditions vary from day to day the experiment will be run over six days. Each golfer will do five drives with a combination of golf ball and driver on each day. The lengths of the five drives will be averaged to give one value. Each combination of ball and driver is used once on each day and once by each golfer. Design: Source df Factors: Is factorial crossing used? Nuisance variables: 6