Wisconsin’s Polytechnic University UW-STOUTKeeping Applied Science Alumni Informed SPECIAL POINTS OF INTEREST: New Faculty Student Achievements Almuni Updates Keeping Informed Fall 2009 News from Applied Science Hello alums! I hope that all is well in your respective careers and personal lives. It has been a busy semester on campus with the move into the new Jarvis Hall addition. It is spectacular from my view; I have toured a few of you around this semester, and would be glad to provide a tour if you are coming through town. As you can see from the picture, the new addition is spectacular on the outside and even more exciting inside. Next fall there will be a grand opening, and we will be sending out formal invites to all of you for this significant event. We continue to hire new faculty with Dr. Jennifer Grant as our newest hire, by way of the Medical University of South Carolina. She is a proteomicist by training, and in the coming semester she will teach BIO 425-Proteomics; this is likely the first and only proteomics course taught at the undergraduate level in the country. You’ll find more about Dr. Grant in the following pages. Also new to the Biology department is Dr. Jim Burritt, who comes to us from Montana State and is teaching microbiology. More about Dr. Burritt will be featured in the Spring 2010 issue. Dillon graduate, who, like some of you has plans to attend pharmacy school next year. Other alums have also had some professional success: most recently Andy Smith (class of 2006) had his Ph.D. research highlighted in the After 38 years on campus teaching thousands of students the finer points of instrumentation as well as environmental and food chemistry, Dr. Marty Ondrus of the Chemistry department will retire in December. His enthusiasm in the classroom will be greatly missed. The program continues to grow and our students continue to be very successful. This December we will proudly watch Ashley New York Times Science section, because he has developed a new, more permanent blue pigment that may revolutionize the dye industry. Check out Andy’s links here: Andy’s Video & NYT Article. Best wishes to everyone for a safe and happy holiday season and a happy new year. PAGE New Faculty: Jen Grant New to the Applied Science program, biology department this year is Dr. Jennifer Grant, who is currently teaching BIO-101 and preparing for Stout’s first course in proteomics, BIO-425, to be launched in spring 2010. For those who might not know, proteomics is the study of the structure, function, interactions and control of proteins, as they are the main components of the physiological metabolic pathways of cells. The term was first coined in 1997 to make an analogy with genomics, the study of genes. Dr. Grant maintains interests in the proteomic impact of gender on the aging of the heart, as well as investigations into why invasive plants are so devastating to local flora. Having trained at several national protein mass spectrometry centers, Dr. Grant has harnessed her expertise in biochemistry to develop quantitative mass spectrometric approaches to under- stand the proteomics changes associated with cardiac and neurological pathophysiology. She received her bachelor’s degree from the Oberlin College chemistry department, and her PhD from the University of Wisconsin-Madison Pharmacology Department. She maintains active interests in leadership issues affecting students, scientists and scholars. Presently, she is cochair of the focus group on undergraduate education in mass spectrometry for the American Society of Mass Spectrometry. In her spare time, Jen likes to hike and explore nature, which is a plus for a proteomicist interested in novel organisms. Student Achievements: Kendra Kilawee’s Sojourn in Spain In the spring of 2008 I received an email directed towards all Spanish minors offering a yearlong study-abroad program in Palma de Mallorca, Spain. That September I got on a plane that began one of the most difficult but rewarding experiences of my life. Reflecting back, I would never change a second of it. All the people I met, the places I saw and the things I did hardly came easily, but together they changed my view of many of the obstacles I face here and helped focus my interests and aspirations as I continue my education. Palma de Mallorca is the capitol city lo- cated on the largest of the Balearic Islands in the middle of the Mediterranean Sea. The two major languages are Spanish and Catalan and even though I studied Spanish for five years, I felt completely out of my element once I stepped off the plane. Thankfully I had a friend from Palma who let me sleep on her couch as I searched for an apartment. She helped me buy a cell phone and guided me as I tried to figure out how to adjust to life in Palma. I never thought that simple everyday tasks like buying toothpaste, ordering a coffee or going grocery 2 A Sojourn in Spain cont’d shopping would be so mentally exhausting. When I met many of the other students who were studying abroad at the university, I was relieved to learn that we all felt the same about being there: completely and utterly lost. Not only was I trying to adjust to a life completely different from what I was used back in the American Midwest, but I was trying to adjust to speaking and understanding Spanish every day. Sticking with the other German, Italian, Dutch and Austrian students made me feel like I belonged there and it began to feel exciting and fun instead of so frustrating. One of my favorite memories of being in Europe was just sitting in a restaurant and realizing that I was surrounded by friends from all over, but we all had to speak the common language that everyone knew, which at the time was Spanish. I began to book plane tickets with new found friends to other parts of Europe so I could take advantage of the time I spent there and travel as much as I could. From September of 2008 to June of 2009, I traveled around Bavaria in Germany, spent New Year’s Eve in Barcelona, Spain, learned to ski in the Alps of northern Italy and got to experience the infamous double-decker busses of London, England. Some of the classes that I took while attending the University of the Balearic Islands were microbiology, biochemistry and molecular cell biology, all taught in Spanish. I was trying to fulfill some of my missing credits, but found out after my first semester exams that I really wasn’t catching on to the material as well as I thought. After going to the classes, translating notes and lectures and then trying to take the exams, I felt like I had been attending the wrong class the entire semester. It was as if I hadn’t studied a thing as I read through the exam and only recognized less than half of the questions being asked. It was after those first semester exams that I realized the reason my classes were so small was because most of the students who were registered didn’t go to class-they simply studied on their own, memorized information and then hopefully passed the exam at the end. This was an aspect of many European universities that American students have a hard time adjusting to. Coming from Stout, I was used to mandatory attendance at classes with the application of that knowledge to the associated laboratory. In the biology PAGE program at UIB I felt that many of the students were excellent at memorizing and taking exams, but in the laboratories, which were one-week sessions for the entire semester class, I could see that many of them did not understand a lot of what we were working on. I was fortunate to be in labs at UIB that covered material I had practiced at Stout like DNA electrophoresis, so the language barrier was less of an issue and I could follow along relatively easily. From arriving in Spain, to traveling around Europe, and studying at the University-- all provided me with experiences that will forever be in my memory. Whether good or bad, when all put together, the obstacles and feelings I had throughout those two semesters are difficult to explain, but have made me a much stronger person. I am now proficient in Spanish, understand many science terms in the Spanish language and have international friends that I hope to someday visit. I would never take back a second I spent in Mallorca and hope to someday return to Europe for another extended period of time. 3 Student Internship: PAGE Heather Schrader - Getting Fired Up at NIST Every summer, the National Institute of Standards and Technology (NIST) accepts a select number of undergraduates for their Summer Undergraduate Research Fellowship (SURF). These students are given the opportunity to do hands-on ISO/TS 19 700 Furnace research in a national laboratory setting. Each student is placed in one of the ten NIST research laboratories and paired with a NIST employee who becomes the student’s advisor and mentor. Students assist their advisors in whatever research his or her advisor is conducting. This past summer, I was selected to work in the Building and Fire Research Laboratory under the supervision of Dr. Nathan Marsh. The summer began with lots of safety training, reading up on the research I would take part in, and organizing data that had already been collected. After I had completed all of the required safety training, I began to help Dr. Marsh in his lab. Our research was broken into two parts. The first part consisted of the validation of the ISO/TS 19700 Tube Furnace. In the second part, cables used in nuclear power plants were supplied to us by the Nuclear Regulatory Commission. We were asked to determine what gases were produced if the cables were ignited, what the concentrations of those gases are and what effect the gases would have on plant operators and staff. To determine the gases and concentrations produced when the cables ignite, a cable was placed in the ISO/TS Tube Furnace and the gases collected in a dilution chamber. The concentrations of gases were measured using Nondispersive Infrared (NDIR) and Forurier Transform Infrared (FTIR) sensors. This experience was invaluable to me. It gave me a hands-on experience that is difficult to rival. I received instruction from some of the best scientists in the nation and was able to work with instruments that are not typically found in college laboratories. It gave me practice in all portions of scientific research, from reading and literature research, to running experiments and recording data, and finally to interpreting that data and drawing conclusions. I had much fun on this adventure. In the simplest of terms, I spent the summer burning things and getting paid for it! I made new friends, visited historic places and sites of national interest and generally had a blast living in an extended stay hotel, living with my suite-mates, and being independent. I highly recommend the NIST internship experience and would be very willing to participate once again. 4 Alumni Updates: PAGE Matt Prissel: Biomimetics in Montana Hello to former class of 2005, fellow AppSci alum, and current AppSci students. I’m Matt Prissel, a Sales and Support alumni. After graduating in 2005, I moved out to Bozeman, MT to begin graduate work in chemistry at Montana State University. There I began a PhD in Chemistry, specifically in biomimetic nanomaterials, under the guidance of Dr. Trevor Douglas and Dr. Mark Young. The research in the labs of Douglas and Young is almost as varied and unique as the students and researchers involved. The work can be distilled to describing it as using protein cages (think a nanosized container made of protein) to template the synthesis of novel materials, encapsulate and deliver therapeutic compounds, or build nano-sized hierarchical structures. The possibilities indeed are endless. Already applications in drug delivery, alternative energy, vaccination against pulmonary infection, ultra-capacitance, and even understanding problems in astrobiology have been/are being pursued. In my research, I focused on using protein cages to template the synthesis of novel catalytic materials. Using proteins as platforms to synthesize inorganic materials turns out to be very important in that this approach provides the ability to do what biology does inherently well, and humans have an incredibly difficult time doing - that is to synthesize inorganic materials at ambient conditions. Think about materials such as bone and teeth, sea shells, or eggs--biology makes all these readily and uniquely. Conversely, interesting man-made materials such as quantum dots currently involve the use of nasty solvents, and high temperatures. What if one was able to make discrete sizes of quantum dots using proteins in an aqueous, one-pot synthetic scheme? That would be cool! And, as it turns out it is possible, and it is cool! The proteins used my research are a ferritin from humans or horse, and the viral coat protein from Cowpea chlorotic mottle virus (CCMV), which infects cowpea plants. Ferritin is 12 nm spherically shaped protein, with cubic symmetry, composed of 24 identical subunits; it functions in biology to store iron in the body or host organism, protecting it from oxidative stress. The CCMV coat protein used is void of any nucleic acid (it isn’t infectious) and is one of the most studied viruses. It is also spherical in shape, possessing icosahedral symmetry, is 30 nm in size, and composed of 180 identical subunits. What these cages give is the ability to control size and shape at the nano size regime in an incredibly controlled manner. We used these protein cages to synthesize iron oxides, polyoxomolybdates, and molybdenum sulfides. These materials are interesting at the nano size because of the catalytic properties they take on. Processes such as hydrogen evolution (fuel cell applications), photocatalysis, photochromism (auto- dimming mirrors) are all possible. Polyoxomolybdates have anti-tumor properties. These protein cages filled with polyoxomolybdate could one day act as targeted nano anti-tumor agents. Applied Science at Stout provided me the scientific background, support group, and technical skills needed to succeed in a high-tech, high paced research setting. Of course, being in Big Sky country, I’ve also made good use of the mountains by skiing Big Sky, Moonlight Basin, and Bridger Bowl every season, and enjoying Yellowstone National Park. It’s a great place to live! 5 UW-STOUTKeeping Applied Science Alumni Informed . The goal of this newsletter is to keep alumni in touch with the Applied Science program. Please update your contact information so that we can keep in touch with you in upcoming newsletters. Share this with your other Applied Science alumni that you are in contact with, we would love to keep them informed also. Please mail these contacts to the address on the below or send your updated information at apsc@uwstout.edu. 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