Annabelle CESARO
EA 4708, I3MTO, Université d’Orléans
Maître de Conférences
Mail : annabelle.cesaro@univ-orleans.fr
Tel : 02 38 49 25 53
UFR Collegium Sciences et Techniques, Pole STAPS
(Bâtiment Physique Chimie, salle 143)
Université d’Orléans
Allée du Château
BP 6237
45062 Orléans Cedex 2
Thème de recherche / mots clés : biologie du cartilage et de l’os, inflammation, immunité,
pathologies inflammatoires chroniques
Principales publications :
Tsai SY, Segovia JA, Chang TH, Morris IR, Berton MT, Tessier PA, Tardif MR, Cesaro A,
Bose S.DAMP molecule S100A9 acts as a molecular pattern to enhance inflammation during
influenza A virus infection: role of DDX21-TRIF-TLR4-MyD88 pathway. PLoS Pathog.
2014 Jan;10(1):e1003848
Chamaillard M, Cesaro A, Lober PE, Hober D. Decoding norovirus infection in Crohn's
disease. Inflamm Bowel Dis. 2014 Apr;20(4):767-70.
El Azreq MA, Boisvert M, Cesaro A, Pagé N, Loubaki L , Allaeys I, Chakir J, Poubelle PE,
Tessier PA, Aoudjit F. Blockade of α2β1 integrin reduces the severity of murine collageninduced arthritis and is associated with a decrease in Th17 cell activity. J Immunol. 2013 Dec
15;191(12):5941-50.
Simard JC, Cesaro A, Chapeton-Montes J, Tardif M, Antoine F, Girard D, Tessier PA.
S100A8 and S100A9 activate the expression of inflammatory mediators cytokines and
regulate the NLRP-3 inflammasome via ROS-dependent activation of NF-ĸB. Plos One. 2013
Aug 19;8(8):e72138. doi:10.137
Chargui A, Cesaro A, Mimouna S, Fareh M, Brest P, Naquet P, Darfeuille-Michaud A,
Hébuterne X, Mograbi B, Vouret-Craviari V, Hofman P. Subversion of Autophagy in
Adherent Invasive Escherichia coli-Infected Neutrophils Induces Inflammation and Cell
Death. PLoS One. 2012;7(12):e51727. doi: 10.1371
Cesaro A, Anceriz N, Plante A, Page N, Tardif M, Tessier PA: An inflammation loop
orchestrated by S100A9 and calprotectin is critical for development of arthritis. PLoS One.
2012;7(9):e45478. doi: 10.1371
Brest P, Lapaquette P, Souidi M, Lebrigand K, Cesaro A, Vouret-Craviari V, Mari B, Barbry
P, Mosnier JF, Hébuterne X, Harel-Bellan A, Mograbi B, Darfeuille-Michaud A & Hofman P.
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of
IRGM-dependent xenophagy in Crohn's disease. Nat Genet. 2011 Mar;43(3):242-5. Epub
2011 Jan 30.
Brest P, Corcelle EA, Cesaro A, Chargui A, Belaïd A, Klionsky DJ, Vouret-Craviari V,
Hebuterne X, Hofman P, Mograbi B. Autophagy and Crohn's disease: at the crossroads of
infection, inflammation, immunity, and cancer. Curr Mol Med. 2010 Jul;10 (5):486-502.
Cesaro A, Brest P, Hofman V, Hébuterne X, Wildman S, Ferrua B, Marchetti S, Doglio
A,Vouret-Craviari V, Galland F, Naquet P, Mograbi B, Unwin R, Hofman P.: Amplification
loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells
in response to neutrophil transepithelial migration. Am J Physiol Gastrointest Liver Physiol.
2010 Jul;299 (1):G32-42. Epub 2010 Feb 25.
Cesaro A, Abakar-Mahamat A, Lassalle S, Hebuterne X, Hugo JP, Mograbi B, Hofman P.:
ADAM17 and TIMP3 are differentially regulated in inflamed intestinal epithelium: role of
neutrophil transepithelial migration. Am J Physiol Gastrointest Liver Physiol. 2009 Jun;
296(6):G1332-43.