Cognitive Enhancement Through Stimulation of the Chemical Senses Phillip R. Zoladz and Bryan Raudenbush Wheeling Jesuit University Finding a non-pharmacological adjunct to enhance cognitive processing in humans would be beneficial to numerous individuals. Past research has consistently noted a significant interplay between odors and human behavior; for example, the administration of particular odorants enhances athletic performance, mood, and sleep quality. In addition, odorants have a differential effect on human behavior, dependent upon route of administration (retronasal vs, orthonasal). The following study examined the differential effects of odoranis on cognition based upon route of administration. During Phase I, 31 participants completed cognitive tasks on a computer-based program (Impact®) under five "chewing gum" conditions (no gum, flavorless gum, peppermint gum. cinnamon gum, and cherry gum). During Phase 11, 39 participants completed the cognitive tasks under four odorant conditions (no odor, peppermint odor, jasmine odor, and cinnamon odor). Results revealed a task-dependent relationship between odors and the enhancement of cognitive processing. Specifically, cinnamon, administered retronasally and orthonasally, improved participants' scores on tasks related to attentional processes, virtual recognition memory, working memory, and visual-motor response speed. Implications are discussed in relation to providing a nonpharmacological adjunct to enhance cognition in the elderly, individuals with test-anxiety, and those with symptoms of dementia. Finding a non-pharmacological adjunct to enhance cognitive processes in humans would be both groundbreaking and readily accepted by society. Attempting to enhance cognitive processing by such measures could ultimately reduce a person's perceived cognitive effort for a task, while still allowing for an enhancement of his or her overall performance on that task. Since pleasant odors induce positive affective reactions, some have argued that the mere presence of such odors may also lead to cognitive, social, psychological, physiological, and physical performance enhancements, and evidence does exist to support this position. For example, Knasko (1992) found that a lemon odor led to fewer reports of health symptoms, and Rottman (1989) noted that jasmine odor enhanced individuals' performance on problem-solving tasks and led the Author info: Correspondence should be sent to: Dr, Bryan Raudenbush, Wheeling Jesuit University, Dept. of Psychology, 315 Washington Ave., Wheeling, WV 26003. E-mail at raudenbc@wju.edu. North American Journal ofPsychology,2005,Vo\. 1,"No. 1, 125-140. ©NAJP 126 NORTH AMERICAN JOURNAL OF PSYCHOLOGY participants to indicate higher levels of interest and motivation to the task. Raudenbush, Koon, Meyer, and Flower (2002a) found that peppermint odor reduced ratings of pain over time and increased participants' overall pain tolerance, as measured by a cold pressor test. Participants also reported reduced mental, physical, and temporal workload requirements, lower effort and frustration, and increased performance and vigor in the presence of peppermint odor. Peppermint odor significantly increased oxygen saturation and blood pressure, providing evidence for its ability to physiologically arouse the human body. Raudenbush, Meyer, and Eppich (2002b) found that during a treadmill stress test peppermint odor reduced measures of workload, effort, fatigue, and frustration, while increasing self-evaluated performance and vigor. Raudenbush, Corley, and Eppich (2001) found peppermint odor increases running speed, handgrip strength, and the number of push-ups performed during a physical workout session. Despite the numerotis reports that support the notion of odorenhanced performance, however, some research has revealed the converse. For instance, research has shown that the presence of a pleasant lavender odor significantly undermines the performance of working memory, reaction time for memory and attention based tasks, and arithmetic reasoning (Ludvigson & Rottman, 1989; Moss, Cook, Wesnes, & Duckett, 2003). Thus, it would seem that it is not the mere presence of a pleasant odor that enhances performance, but rather something specific to the odorant itself. Recent research has compared the effects of orthonasal and retronasal odorants on human behavior. According to Pierce and Halpem (1996), stimuli arrive at the olfactory epithelium through two distinct pathways: an orthonasal stimulus travels inward through the naris towards the olfactory mucosa, while a retronasal stimulus travels via the mouth to the nasopharynx. While Raudenbush, et al. (2002h) found that an orthonasal administration of peppermint odor significantly enhanced athletic mood, performance, and workload, Zoladz, Raudenbush, Fronckoski, and Price (2003) did not replicate such fmdings when using a retronasal administration of the same odor. Since research has shown that it is easier for an odorant to affect human behavior if it is administered orthonasally (Puttanniah & Halpem, 2001), the effects odorants have on human behavior appears to be partially dependent upon the route by which they are administered. The following experiments were designed to assess tiie effects of retronasal (Phase I) and orthonasal (Phase II) odorant administration on cognition. In Phase I, participants completed multiple cognitive tasks under five retronasal odorant (via chewing gum) conditions (peppermint gtim, cirmamon gum, cheny gum, flavorless gum, and no gum). In Phase Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 127 n, participants completed multiple cognitive tasks under four orthonasal odorant conditions (peppermint odor, cinnamon odor, jasmine odor, and no odor). Participants also con:q)leted questionnaires assessing meastires of mood and workload. It was hypothesized that orthonasal odorant administration would have a greater impact on cognitive performance. Given the fmdings of past research, the administration of peppermint odor was expected to increase individuals' alertness and attention, ultimately enhancing their cognitive performance. PHASE I: RETRONASAL Chewing flavored gum facilitates episodic and working memory in humans (Wilkinson, Scholey, & Wesnes, 2002). Sesay, Tanaka, Ueno, Lecaroz, and De Beaufort (2000) report that mastication alone improves regional cerebral blood flow, and Yagyu, Kinoshita, Hirota, Kondakor, Koenig, Kochi, and Lehmann (1998) suggest that the chewing of flavored vs, non-flavored gum activates different neuronal populations in the brain. Most importantly, Morinushi, Masumoto, Kawasaki, and Takigawa (2000) showed that the specific flavor of gum, in addition to mastication, increases brain activity. Method Participants. Participants were 31 young adult volunteers (13 males, 18 females, mean age = 20.19 years) obtained through convenience san^ling. Participants were students in a variety of psychology classes and were awarded course credit. Stimuli. Gum stimuli consisted of peppermint (Wrigley's Extra* Peppermint), cinnamon (Wrigley's Big Red®), cherry (Fruit Stripe®), and flavorless gum (gum base). Cognitive Performance Software. The Impact® software was used to measure a variety of aspects of participants' cognitive performance and functions (see Appendix A). Internal reliability for this instrument ranges from .88 to .94 in various san^les, with test-retest reliability of .80 (Iverson, Lovell & Collins, 2002; Iverson, Lovell, Collins, & Norwig, 2002). Procedure. Participants were briefed as to the nature of the study, produced written consent, and provided demographic infonnation. They then began chewing a piece of gum (cinnamon, peppermint, cherry, or flavorless) for five minutes prior to the cognitive assessment, or, in the control condition, sat quietly for five minutes instead of chewing gum. After five minutes had elapsed, participants completed the Impact® test, with those participants in the gum conditions continuing to chew the gimi throughout the duration of testing. 128 NORTH AMERICAN JOURNAL OF PSYCHOLOGY The protocol was completed five times in a repeated measures design with each participant exposed to each condition, and with each condition separated by at least 24 hours. The order of the conditions was randomly assigned, and each session lasted approximately 45 minutes. The Impact test has five different versions of each sub-test, which limited practice effects. Results Cognitive Performance Scores. One-between (sex), two-within (cognitive task, gum condition) ANOVAs were performed to compare cognitive scores for tasks on the Impact® test. One-within (gum condition) ANOVAs were performed to compare composite scores of verbal memory, visual memory, visual motor speed, reaction time, and impulse control in the gum conditions. Alpha was set at .05, and Tukey HSD Post-hoc contrasts were performed to determine the direction of effects. Design Memory Task. A trend was found for gum condition, Ftuf, = 2.361, p = .OSl. Greater design memory scores were found in the TABLE 1 Means and Standard Errors for the Cognitive Performance Scores in Phase I Task Word Discrimination Design Memory X's and O's Symbol Matching Color Match Three Letters Verbal Mem. Composite Visual Mem. Composite Visual Motor Speed Comp. Reaction Time Composite Impulse Cont. Composite No Gum 45.89 (.64) 33.19 (1.00) 29.03 (.33) 9.16 (-11) 2.50 (.03) 24.93 (.48) 86.68 (1-78) 75.52 (2.39) 41.16 (1.16) ,54 (01) 10.42 (2.22) Flavorless 45,08 (.87) 34.52 (.90) 29.01 (.40) 9.15 (.10) 2,48 (-04) 25,40 (.36) 86.10 (1.48) 75,26 (2.31) 42.35 (1-01) .52 (.01) 12.00 (2.83) Condition Peppermint 46,89 (.50) 33,25 (.78) 29.05 (.43) 9.13 (-10) 2.71 (.16) 25.7! (.29) 87.87 (1.57) 76,94 (2.14) 41.62 (1.00) .54 (-01) 12.36 (3,02) Cinnamon 45.99 (.63) 34.84 (-95) 28.98 (.41) 9.20 (.10) 2.65 (,!6) 25.91 (34) 89.61 (1.45) 76.26 (2.44) 41,96 (.99) Cherry 45.37 (.81) 33.07 (-98) 29.94 (.45) 9.27 (.09) 2.72 (,17) 25.70 (.37) 88,94 (1,42) 75.19 (2,29) 41.57 (1.28) .52 .53 (,01) 11.36 (2,49) (-01) 11.87 (2.86) Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 129 cinnamon gum condition, as compared to the no gum condition and the chenry gum condition. There was a significant Gum x Task interaction for design memory indicating that among the flavored gum conditions, cinnamon- and peppermint-flavored gum produced the greatest delayed memory percent correct scores, F^o.sso = 2.034, p<.0\. There was no significant Gum x Sex interaction for scores on the design memory task, F4.,,6 = 2.033. p>.05. FIGURE 1. Mean Overall Three Letter Memory Scores for the Gum Conditions in Phase I. 24 No Gum Flavorless Gum Peppermint Cinnamon Cheny Three Letter Task. A trend was found for gum condition, /^j.ue = 2,004, p = .099. Scores for the three letter task in the cinnamon gum condition were greater than those scores in the no gum condition (see Figure 1). There was also a significant Gum x Task interaction indicating that the three letter total percent correct scores in the flavored gum conditions were significantly greater tlian those scores in the flavorless gum condition and the no gxim condition, FJO.SBC = 1.625, p<.05 (see Figure 2), There was no significant Gtim x Sex interaction for scores on the three letters task, /^4,|,6 = ,566,/)>.O5. No other significant effects were found for the cognitive performance scores in Phase I. Means and standard errors for all measures can be found in Table 1. Discussion These results provide additional support that retronasal odorants can enhance human behavior. While peppermint gum played a minor role in 130 NORTH AMERICAN JOURNAL OF PSYCHOLOGY the results of design memory scores, cinnamon gum had the most consistent directional influence on participants' cognitive performance. Data trends indicated that design memory scores in the cinnamon gum condition were greater than design memory scores in the no gum and cherry gum conditions. Scores for the three letters task in the cinnamon gum condition were also greater than those in the no gum condition, These results suggest that a retronasal administration of a cinnamon odorant has the potential to increase an individual's attentiona! processes, virtual recognition memory, working memory, and visual-motor response speed. Since the fmdings were not statistically significant, however, route of administration may be playing a role in this effect. FIGURE 2 Mean Three Letter Memory Total Percent Correct Scores for the Gum Conditions in Phase I. 1 T 98,5 97.5 • 196.5 T 95,5 94.5 93.5 No Gum Flavwless Gum Peppermint Cinnamon Cheny The significant Gum x Task interaction for design memory suggested that among the flavored gum conditions, cinnamon- and peppermintflavored gum produced the greatest delayed memory percent correct scores. Thus, the cinnamon- and peppermint-flavored gums allowed for participants to retain information in their memory for a longer period of time. The significant Gum x Task interaction for the three letters task suggested that the total percent correct scores in the flavored gum conditions were significantly greater than those scores in the flavorless gum and no gum conditions. This is of particular importance as it suggests that flavored gum (in general) has the potential to enhance working memory and visual motor response speed. Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 131 Thus, the effects of retronasal odorants on human behavior are taskdependent; i.e., retronasal odorants enhance performance on particular cognitive tasks. Evidence that particular flavors of gum can enhance working memory links directly to research performed by Wilkinson, et al. (2002), where flavored gum (Wrigley's Extra* Spearmint) facilitated episodic memory and working memory. The present study finds the same effects, but for different flavors of gum. PHASE n: ORTHONASAL Previous research has shown that an orthonasal peppermint fragrance can significantly enhance athletic performance (Raudenbush, et al., 2002b; Raudenbush, et al., 2001), decrease perceived workload for a given task (Raudenbush, et al.. 2002a, Raudenbush, et al., 2002b), induce physiological arousal (Raudenbush, et al., 2002a), and enhance one's mood (Knasko, 1992). In Phase II, it was hypothesized that the adrtunistration of a peppermint fragrance would significantly enhance participants' cognitive performance. Given the findings of Phase I, it was also hypothesized that the administration of a cinnamon fragrance would significantly enhance participants' cognitive performance, particularly on the design memory and three letter tasks, which were enhanced by the administration of this odorant in Phase I. It was expected that these effects would be more pronounced m Phase II, given an orthonasal route of administration. Method Participants. Participants were 39 young adult volunteers (3 males, 36 females, mean age = 18.38 years) obtained through convenience sanpling, and were different from those participants in Phase I. Participants were students in a variety of psychology classes and received course credit for participation. Three participants were removed from primary data analyses to limit age variance [ages >30, (A/ = 45.33, SD = 10.79)]. Stimuli. In each odorant condition, peppermint, cinnamon, or jasmine odor (Atdrich Co.) was added to low flow (1.3 Umin) oxygen via an Airsep Newlife oxygen concentrator, and delivered to the participants through a nasal cannula bi-rhinally. In the control condition, only low flow oxygen was administered. The jasmine condition was included as a further con^arison, since its effects are quite the opposite of peppermint and cinnamon, i.e. relaxing rather than stimulating (Raudenbush, Koon, Smith, & Zoladz, 2003). No cherry odorant condition was used due to the findings of Phase I, where cherry gum had no significant in5)act on cognitive performance. 132 NORTH AMERICAN JOURNAL OF PSYCHOLOGY Cognitive Performance Software. The Intact® sofhvare was en^loyed, as per Phase I. Additional Inventories. Profile of Mood States (POMS; McNair, Lon, & Droppleman, 1971), The POMS contains 65 mood adjectives to which participants indicate the extent to which each describes them. Sub-scales related to fatigue, anxiety, and alertness are calculated. NASA-Task Load Index (NASA-TLX; Hart & Staveland, 1988). The NASA-TLX measures workload along three dimensions (mental, physical, and ten^oral demand) related to demands imposed on the participant by the task, and three dimensions (effort, frustration, and performance) related to the interaction of the participant and the task. Procedure Participants were briefed as to the nature of the study (although not about which odors would be used), produced written consent, provided demographic information, and completed a pre-test POMS questionnaire. TABLE 2 Means and Standard Errors for the Cognitive Performance Scores in Phase II Task Word Discrimination Design Memory X's and O's Symbol Matching Color Match Three Letters Verbal Memory Composite Visual Memory Composite Visual Motor Speed Comp. Reaction Time Composite Impulse Control Composite No Odor 44.61 (.79) 38.93 (1,08) 28.69 (.21) 9.18 (.08) 2.47 (.04) 25,55 (.25) 88.31 (1.30) 73.10 (2.13) 41.11 (1.16) .54 (.01) 9,08 (1.44) Condition Peppermint Jasmine 44.25 44,39 (.60) (.61) 40.19 39.15 (1.08) (1.03) 28,61 28.73 (.24) (.20) 9.25 9.16 (.09) (.07) 2.51 2.50 (.03) (.03) 25.59 25,13 (.25) (.36) 87.00 87.82 (1.44) (1,26) 73.95 76.87 (2.27) (1-89) 42,63 41.57 (1,00) (1.09) .54 .53 (.01) (•01) 9.59 9,08 (1,65) (1.22) Cinnamon 44.93 (.59) 40,68 (1.04) 28.74 (.27) 9.25 (.09) 2.48 (.04) 25,87 (.26) 89.44 (1.27) 75.90 (2.04) 41.52 (1.22) .53 (01) 9.90 (1.59) Zotadz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 133 After connection to the odorant delivery system, participants completed the Impact* test. Finally, participants completed a post-test POMS questionnaire and completed the NASA-TLX workload assessment. The protocol was performed four times in a rejwated measures design with each participant experiencing all conditions, and with each session being separated by at least 24 hours. The order of the conditions was randomly assigned, and each session lasted approximately 4S minutes. Results Cognitive Performance Scores.' Two-within (cognitive task, odor condition) ANOVAs were performed to compare scores for the various cognitive tasks among the odorant conditions. One-within (odor condition) ANOVAs were performed to compare composite scores among the odorant conditions. Alpha was set at .05 for all analyses, and Tukey HSD Post-hoc contrasts were perfonned to determine lhe direction of effects. FIGURE 3 Mean Design Memory Delayed Memor>' Percent Correct Scores and Design Memory Total Percent Correct scores for the Odorant Conditions in Phase II. No Odor Peppermint Jasmine Cinnamon • Delayed Memory Percent Correct • Total Percent Correct Design Memory Task. There was no significant effect for odor condition, fj.n* = 1,696. p>.05. However, there was a significant Odor x Task interaction, suggesting that delayed memory percent conect scores and total percent correct scores were greatest in the cinnamon odorant condition, F\t,6u "= I.710,;?<.05 (see Figure 3). 134 NORTH AMERICAN JOURNAL OF PSYCHOLOGY Three Letter Task. There was no significant effect for odor condition, ^j.tn - 1.910,;? = .132. There was a significant Odor x Task interaction, suggesting that the percent of total letters conect scores were greatest in the cinnamon condition. Fis.s7o = 2.461, /K.Ol. No other significant effects were found for scores of cognitive performance in Phase II. Means and standard errors for all measures can be found in Table 2. Workload Measures. One-within (odor condition) ANOVAs were performed to assess workload differences among the odorant conditions. No significant effects were found for any of these measures. Mood Measures. Measures of mood were calculated before and after each condition by use of the POMS questionnaire. For each condition, the difference was taken between the pre- and post-recordings as an indication of the change in these variables during the experimental session. One-within (odor condition) ANOVAs were performed to compare these changes. Vigor. A significant effect was found for odor condition, Fj.m = 3.058, /f<.05. Levels of vigor in the peppermint condition showed a significantly smaller prc-post decline than the levels of vigor in the no odor and cinnamon conditions. Fatigue. A significant effect was found for odor condition, Fj^w = 2.922, p<.05. Levels of fatigue in the peppermint and jasmine conditions showed a significantly greater pre-post decline than the levels of fatigue in the cirmamon condition. No other significant effects were found for die measures of mood in Phase II. Discussion The results of Phase II support those of Phase I, suggesting that cinnamon, administered retronasally and orthonasally, exhibits promise in enhancing cognition. Once again, however, the relationship between odorant administration and cognitive enhancement is task-dependent. The significant interaction for design memory suggests that delayed memory percent correct scores and total percent correct scores were greatest in the cinnamon odorant condition; this is consistent with the results of Phase I, where the cinnamon-flavored gum significantly enhanced design memory delayed memory percent correct scores. Additionally, the significant interaction for the three letters task indicated that the percent of total letter correct scores were greatest in the cinnamon odorant condition. Results of Phase I indicated that the three letter total percent correct scores were greater in the fiavored gum conditions than in the no gum and flavorless gum conditions. The Phase n finding extended this interaction in Phase I, suggesting that the cinnamon odorant has a more pronounced effect (than other odorants) for Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 135 this task when administered orthonasally—route of administration does play a role in the amount of influence an odorant has on the enhancement of cognitive processing related to this task. This finding is con^arable to that of Puttanniah, et al. (2001) who found that odorants have a greater effect on human behavior if they are administered orthonasally. Regarding the task-dependent relationship between odorants and cognitive enhancement, the fmdings in Phase II suggest that cinnamon odorant has the greatest potential to enhance attentional processes, virtual recognition and working memory, and visual-motor response speed. Of primary importance is the fact that cinnamon had a more pronounced influence on cognitive processing for the same scores on the same tasks in Phase II as it did in Phase I. The significant odorant effects for pre-post changes in levels of vigor and fatigue support the notion that peppermint is an invigorating odorant that prevents fatigue from affecting individuals during a task. However, since the peppermint odorant had no significant effect on the cognitive performance of individuals, these results provide no evidence for an interaction between peppermint, mood, and cognition. FIGURE 4 Mean Overall Three Letter Memory Scores for the Odorant Conditions in Phase II: Data from Participants Excluded &om Original Data Analyses Due to Age. 16 No Odor Peppermint Jasmine Cinnamon Summary Past research has consistently found that the administration of a stimulating peppermint fragrance increases pain tolerance (Raudenbush, et al, 2002a), reduces workload (Raudenbush, et al., 2002a; Raudenbush, 136 NORTH AMERICAN JOURNAL OF PSYCHOLOGY et al., 2002b), enhances athletic performance (Raudenbush, et al., 2002b; Raudenbush, et al., 2001), and induces physiological arousal (Raudenbush, et al., 2002a). The present study suggests that another stimulating odorant—cinnamon—can enhance human cognitive performance. The fragrance, administered retronasally and orthonasally, can enhance one's attentional processes, virtual recognition memory, working memory, and visual-motor response speed. The current findings have provide a foundation for ways to improve cognition, and additional groups of individuals should be studied, such as those who are declining cognitively with age, suffering test anxiety, or suffering from diseases that lead to dementia. Though the present study considers non-clinical participants, its findings call for an assessment of cinnamon's effects on the cognition of individuals with such afflictions. Footnote 'in order to examine the effects of age on an odorant's ability to enhance cognition, participants originally excluded from the data analyses were included in two-within (cognitive task, odor condition) ANOVAs to compare their scores on the three letter task. One ANOVA compared scores of all forty-two participants (i.e. older participants plus younger participants), while the other ANOVA solely compared scores ofthe older participants. Three Letters - Older + Younger: There was a significant effect for odor condition, F3_i23 = 3.700, g<.05. Scores on the three letter task in the cinnamon and peppermint conditions were significantly greater than scores on the three letter task in the jasmine condition. Further, there was a significant Odor x Task interaction suggesting that the total sequence correct scores, total letters correct scores, and percent of total letters correct scores were greatest in the cinnamon condition, Fjs,6[5 = 3.826, p<.00\. Three Letters - Older: A trend was found for odor condition, fj.e = 3.726, p = .08. Post-hoc contrasts revealed that scores on the three letter task in the cinnamon condition were greater than scores on the three letter task in the jasmine condition (see Figure 4). Additionally, there was a significant Odor x Task interaction suggesting that the total sequence correct scores, total letters correct scores, and percent of total letters correct scores were greatest in the cinnamon condition, f;j.3o = 6.226, p<.001. Thus, cinnamon, administered orthonasally, may be particularly salient in the enhancement of cognition in elderly individuals. Such a significant fmding provides a solid foundation for finding ways to improve memory and other cognitive functions in individuals experiencing age-related dementia. It also calls for research directed at enhancing these individuals' cognition via orthonasal odorant administration. Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 137 REFERENCES Hart, S. G., & Staveland, L, E, (1988). Development of a multi-dimensional workload rating scale: Results of empirical and theoretical research. In P. A. Hancock and N. Meshkati (Eds.), Human t^enial Wortcload. Amsterdam; Elsevier. Iverson, G., Lovell, M.R., Collins, M.W,, & Norwig, J, (2002). Tracking recovery from concussion using lmPACT: Applying reliable change methodology. Archives ofCtinical Neuropsychology. 17, 770, Iverson, G.. Lovell, M.R,, & Collins, M.W. 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Kinoshita, T,, Hirota, T,, Kondakor, I., Koenig, T.. Kochi, K., & Lehmann, D. (1998). Smell and taste of chewing gum affect frequency domain EEG source localizations. International Journal of Neuroscience, 93, 205-216. APPENDIX A Iir^act Software Program Assessments Assessment #1 - Word Discrimination This test assesses artentional processes and verbal recognition memory. Twelve words are presented on the computer screen, each for approximately 750 milliseconds. Subsequently, participants are presented with 24 different words, 12 of which were part ofthe list they just viewed, and 12 of which were not part ofthe list they just viewed. Participants must decide which words were part of the list and which words were not part of the list by supplying a "yes" or "no" response to each ofthe 24 words presented. Assessment #2 - Design Memory This test assesses attentional processes and visual recognition memory. Twelve various designs are presented on the computer screen, each for approximately 750 milliseconds. After all twelve designs have been presented, participants are presented with 24 different designs, 12 of which were part ofthe list they just viewed, and 12 of which were not part ofthe list they just viewed. Participants must decide which designs were part ofthe list and which designs were not part ofthe list by supplying a "yes" or "no" response to each ofthe 24 designs presented. Assessment #3 - X's and O's This test assesses visual working memory and visual processing speed. Individuals are presented with a random assortment of X's and O's, 3 of which are highlighted in yellow. Participants are required to remember the location of the 3 highlighted letters r I ^ Zoladz & Raudenbush COGNITIVE ENHANCEMENT THROUGH 139 and recall that information after performing a distractor task (i.e. a task that is presented between the primary exposure to the information and the cued recall of that information in an atten^t to challenge the working memory of participants). After viewing the highlighted letters for approximately 1.5 seconds and also performing the distractor task, participants are asked to recall the location ofthe 3 highlighted letters. Participants repeat this task for a total of 4 trials. Assessment #4 - Symbol Matching This test assesses visual processing speed, learning, and memory. At the top of the computer screen, participants are presented with a grid that matches 9 numbers to 9 common symbols (i.e. star, triangle, square, arrow, etc.). At the bottom of the screen, participants are presented with a random symbol to which he or she must tnatch with a number on the top ofthe screen. After 27 practice trials have been completed, the symbols paired with the numbers on the top of the screen disappear. Subsequently, participants are again presented with random symbols at the bottom ofthe screen, and he or she mtist recall to which number the specific symbol was paired. This assessment records a reaction time score and a memory score. Assessment #5 - Color Match This test assesses reaction time and impulse control/response inhibition. Before begitining the assessment, participants are asked to click a "RED," "BLUE," and "GREEN" button as it is presented on the screen. This screening procedure helps assure that subsequent trials will not be affected by color blindness. Thereafter, words are presented in either the same color of ink as the words read ("blue" in blue ink) or a different color of ink ("blue" in red ink). Participants are asked to click on the word only if the word is printed in the same color of ink as the word reads. Assessment #6 - Three Letters This test assesses working memory and visual-motor response speed. Before testing, participants are allotted time to practice a distractor task, consisting of 25 grid blocks ( 5 x 5 grid design) numbered 1-25 in random order. Participants must click on the blocks in reverse order, starting with block #25 and progressing through block #1, Once the test begins, participants are 140 NORTH AMERICAN JOURNAL OF PSYCHOLOGY presented with three consonant letters (e.g. WFL). Immediately after these letters have been displayed, they are removed and the participant must complete the distractor task. He or she is once again asked to perform the numbered grid task described above as quickly as possible. Once 18 seconds have elapsed, the gnd disappears, and the participant is asked to recall the three letters that were displayed on the screen earher.