Chapter 7 – DNA Fingerprinting I. Standard: SFS3. Student will analyze the use of toxicology, serology and DNA technology in forensic investigations. a. Compare STR’s and VNTR’s and explain how they are used to identify an individual. b. Explain the use of DNA database for DNA profiling. II. Learning goals a. Know your VOCABULARY b. What is DNA? What are STR’s? VNTR’s? How are they used to identify a criminal? c. List and describe the 4 basic steps in creating a DNA profile. d. Describe how gel electrophoresis works. III. Reading assignments a. Mandatory: Carefully read All of Ch 7! b. Mandatory: (page 170-171) Read the 5 case studies. c. Answer the questions for the DNA WEBQUEST ( http://www.dnai.org/index.htm ) IV. Writing Assignments a. Design a Children’s Flip Book that explains the 4 steps to creating a DNA profile. Your book must include colored and labeled pictures. The pictures must represent what happens during each step. Follow directions given in class. V. Practical Activity a. DNA Extraction Lab (Onion/Peas/Strawberry) WE WILL NEED 6-8 BLENDERS! b. Enzyme Restriction Activity- “Who ate the Cheese?” c. Match the Lines Activity & DNA Cipher d. Gel Electrophoresis Interactive Activity: http://learn.genetics.utah.edu/content/labs/gel/ e. DNA Gel Electrophoresis Lab f. Exploring DNA online activity (for your review) http://www.umass.edu/molvis/bme3d/materials/jtat_080510/exploringdna/contents/contents.htm g. Online Cold Case Study: http://static.dna.gov/casestudy/ h. OPTIONAL Online Game: http://www.pbs.org/wgbh/amex/dillinger/sfeature/sf_whodunit.html i. OPTIONAL Online Activity: http://www.pbs.org/wgbh/nova/sheppard/ VI. Review: Chapter 7 Review – Complete all Review questions at the end of the chapter. VII. Additional DNA Resources a. http://www.dnai.org/index.htm b. DNA Explained: http://www.scientific.org/tutorials/articles/riley/riley.html c. http://science.howstuffworks.com/environmental/life/genetic/dna-evidence.htm d. Optional: (Bonus Test questions may come from this link) http://www.thenewatlantis.com/publications/liberty-privacy-and-dna-databases http://www.psychologytoday.com/blog/the-measure-madness/201007/the-grim-sleeper-anotherserial-killer-is-caught Test VIII.