Shelby Skelton Yvonne De La Cruz Writing 10-Essay #3 11/16/2013 The Ethics behind Animal Testing As a result of technological advances, people are becoming more cognizant of the impacts of everyday utilized items and materials. Of course testing experimental compounds and substances on human beings is illegal and immoral due to the possible mutations and death that may ensue as an effect. The most logical option at that time was the utilization of animal analog because of their genetic similarity to humans without a government enforced set of rights. Luckily, PETA and several other humanitarian groups in conjunction with the white house has implemented several animal saving practices into the controversial HPV (High Production Volume Chemical Challenge program). However, because the project began in 1999, technology has greatly advanced since its implementation and the need for animal testing has greatly diminished (Bishop 1). These advancement’s implementation is not yet wide spread, calling laboratories to subsequent evaluation in order to protect animal rights. A balance exists between the harm we are willing to cause for the progression of medical research and the resulting cures to deadly diseases. The question becomes how many live are we willing to risk and how many animals are we willing to “consume” in order to same human lives. Consumptions is the commonly referred to term when utilizing animals in testing. Animals are affected by all forms of research, biological, psychological, and consumer testing. The term consumed means no care was taken for the safety of the animal, making the assumption that the damages inflicted would necessitate euthanasia as the most humane option for the not mangled of diseased animal. Further insight into the attitude of researchers can be obtained through a recent report of testing on type 2 diabetes. In order to obtain information, information must be interpreted since, “None of the known single species is exactly equivalent to human diabetes, but each model act as essential tool for investigating genetic, endocrine, metabolic, morphologic changes and underlying aetiopathogenic mechanisms that could also operate during the evolution of type 2 diabetes in humans (Srinivasan 467)”. Although some could interpret this piece of information as being a major breakthrough, if you place this in the context of animals, each model means another animal being consumed. Regardless of the species being experimented upon, a standard of protection should be established for all cognizant living things. Alternatively, if no other alternatives existed, the loss of animal life would be much more justifiable than thousands of individuals losing their lives to experimental drugs or unsafe materials. Overall, researchers attempt to justify their actions by saying that the suffering and loss the animal’s lives impart some miraculous research that furthers medicine in a way that will save thousands of lives further down the road. In an attempt to ensure the safety of the public, the United States government has necessitated the testing to any medication that is placed into the commercial market on animals in order to evaluate possible effects and establish a system of dosages (Latham 2). In few cases, that actually is true, with every drug on the American market as proof of successful animal testing. Until this legislation is overturned, the possibility of replacement-one of the 3 R’s of animal testing reform as advocated by Russel and Burch (Saraf 8)- is unfeasible and instead reduction needs to be implemented instead. Animal rights advocates do not wish to completely obliterate the usage of animals, just streamline the processes in order to minimize losses. “It also recognizes that immediate abolition of all experiments is not possible. Vital medical research must continue to find treatments for diseases with lessens the quality of human and animal life. New consumer products, medicines, and industrial and agricultural chemicals must be adequately tested in order to identify potential hazards to human and animal health and to the environment (Ranganatha)”. In order to still abide by the afore mentioned legislation, the classification of animal has been more loosely adapted in order to protect more important animals while using more common and easy to produce animals such as rats and small organisms who does not possess a significant value to humanity. There exist both benefits and setbacks to removing animal testing from research. According to Ranganatha, “The use of human tissue in toxicity testing is more accurate than the animal models”. Many animals cannot withstand the same dosages necessary to treat human conditions and therefore do not constitute a sufficient analog. However, some basic information obtained from the way that animal cells respond to small non-lethal amounts could provide some insight into how human tissue will respond. This human tissue can be obtained through donors and cadavers to avoid harming the masses and therefore using less animals in the process. Ethical issues are always at the forefront of animal testing, however, financial viability is analyzed far less often. A researcher and advocate for animal research stated, “The set up for conducting animal studies is costly and faculty must be trained in handling animals well (Saraf 8)”. Due to increased Refinement-another of the 3 R’s-animal treatment before the experimentation even begins means that animal experimentation is more expensive than using substitutes such as synthetic skin. Ranganatha provides an example of the successes of an testing substitute with, “InVitro International’s Corrositex (synthetic skin) can provide a chemical corrosivity determination in as little as 3 minutes to four hours, unlike animal testing that often takes two to four weeks (Ranganatha 31)”. Because animals are occasionally used or multiple studies, rarely it may be a better decision to use animals only after all necessary evaluation takes place. Therefore avoiding animal testing could actually provide beneficial in some instances for laboratories due to a greater availability of funds to appropriate. Overall, animal testing should be used sparingly, and only used in order to appease the current legislature in place. Furthermore, lower order sentient beings need to be used whenever animal testing is necessary in order to avoid long-term harm in addition to the research benefit that longterm genetic history can be controlled in laboratory rats. The three R’s of moral animal experimentation needs to be implemented and further regulated by the EPA and FDA. The research industry is reaching a point where animal experimentation alternatives are very much available and financially viable, possibly paving the way for animal testing to eventually be phased out. Works Cited Bishop, Patricia, Joseph Manuppello, Catherine Willett, and Jessica Sandler. "Animal Use and Lessons Learned in the U.S. High Production Volume Chemicals Challenge Program."Environmental Health Perspectives 120.12 (2012): 1631-639. Academic Search Complete. Web. 16 Nov. 2013. Latham, Stephen R. "U.S. Law and Animal Experimentation: A Critical Primer." Hastings Center Report 42 (n.d.): 35-39. Academic Search Complete. Web. 15 Nov. 2013. Ranganatha, N., and J. Kuppast. "A REVIEW ON ALTERNATIVES TO ANIMAL TESTING METHODS IN DRUG DEVELOPMENT." International Journal of Pharmacy & Pharmaceutical Sciences 4 (2012): 28-32. Academic Search Complete. Web. 15 Nov. 2013 Saraf, Shyam, and Vinay Kumaraswamy. "Basic Research: Issue with Animal Experimentation."Indian Journal of Orthopaedics 47.1 (n.d.): 6-9. Academic Search Complete. Web. 14 Nov. 2013 Srinivasan, K., and P. Ramarao. "Animal Models in Type 2 Diabetes Research: An Overview." Indian Journal of Medical Research (2012): 451-72. Academic Search Complete. Web. 15 Nov. 2013 Peer Review Feedback Form Writer: Shelby Skelton Essay: The Ethics Behing Animal Testing To the best of your ability, using the assignment and grading rubric for this course, answer the questions below for your peer accordingly. Peer feedback in this class should be constructive, helpful, and supportive. When finding weak areas in a peer’s work, leave a comment or ask a question to help guide them in the improvement of that area. Clarity—the paper addresses the prompt, there is a clear and concise thesis statement, and an outline of what’s to come. I had a difficult time locating your thesis. Are you opposed or for animal testing? Coherence—the text is easy to understand. Key terms are defined, and a reader’s point of view is considered along with the writer’s perspective. The essay was written in an understandable way, it was very logical based and used a very high lever vocabulary. Cohesion--the text is arranged efficiently and effectively. It has a chronological structure, follows a theme, and the organization fits the topic. The text is very informative about why animal testing is used, and it remains that way throughout. Organization—the paper has a logical, thoughtful, and easy-to-follow structure. There is a thematic/rhetorical thread schema going through the paper. There are effective topic sentences and transitions. The essay is well organized. Development--each body paragraph: 1) provides adequate (quantity and quality) evidence; 2) develops key ideas thoroughly; and 3) moves the argument further along. Each paragraph provided a large volume of research and logical based evidence, however I still had trouble discerning whether or not animal testing was good or bad. Style—the author’s writing is appropriate for the intended audience and for the assignment. The text is interesting to read and appropriately representative of a writer’s identity. Your style seems to be pointed towards the knowledgeable reader. the essay was interesting to read and learn new facts. Flow-- the author’s particular selection of words, construction of sentences, arrangement of ideas, and varied usage of rhetorical strategies is engaging and appropriate for the intended audience. The essay flowed nicely. Logic--explains and supports the problem addressed in a problem-solving thesis. This I believe was your strong point, there were many sources used Mechanics-- the paper observes standard English conventions in spelling, grammar, punctuation, and documentation. I found your grammar to be used correctly. Something I really liked about this piece was: I liked learning about something that I had never heard any information about. Something I found interesting is: The logical reasons why animal testing is used. Something I’d like to ask about this piece is: What kind of animals do they use for different types of products? Reviewer: Aaron Barnhart Peer Review Feedback Form Writer: Shelby Skelton Essay: The Ethics Behind Animal Testing To the best of your ability, using the assignment and grading rubric for this course, answer the questions below for your peer accordingly. Peer feedback in this class should be constructive, helpful, and supportive. When finding weak areas in a peer’s work, leave a comment or ask a question to help guide them in the improvement of that area. Clarity—the paper addresses the prompt, there is a clear and concise thesis statement, and an outline of what’s to come. I think the paper addresses the prompt correctly, however, I think the thesis needs to be improved to address the topic more and to outline what is to come of your paper. I also think the intro sentence could be better, too. Coherence—the text is easy to understand. Key terms are defined, and a reader’s point of view is considered along with the writer’s perspective. For the most part, the text is well-defined and easy to understand. The one main part that was unclear was the 3 R’s of research. I think those need to be laid out and better defined before they are mentioned in the paper several times. Other than that, I thought the paper was easy to understand! Cohesion--the text is arranged efficiently and effectively. It has a chronological structure, follows a theme, and the organization fits the topic. The text is arranged efficiently, I liked how and where you introduced the opposing view. It is not chronological necessarily, but with your paper, I don’t think it needs to be. Organization—the paper has a logical, thoughtful, and easy-to-follow structure. There is a thematic/rhetorical thread schema going through the paper. There are effective topic sentences and transitions. I like the organization of your paper. It could use some smoother transitions, but overall I think the topics flow into one another very nicely. Development--each body paragraph: 1) provides adequate (quantity and quality) evidence; 2) develops key ideas thoroughly; and 3) moves the argument further along. I do think each body paragraph provides adequate evidence, although you could probably include more for a bit more detail. The key ideas are developed well, though, and the argument does progress fluidly throughout the paper. Style—the author’s writing is appropriate for the intended audience and for the assignment. The text is interesting to read and appropriately representative of a writer’s identity. I think the style is appropriate for the given audience and pertains well to the assignment. The text is interesting, especially the part about using skin samples instead of animals, and easy to read. While it is hard to represent the writer’s identity in a research paper, I feel she expressed her opinion on the topic nicely towards the end. Flow-- the author’s particular selection of words, construction of sentences, arrangement of ideas, and varied usage of rhetorical strategies is engaging and appropriate for the intended audience. While I think the diction was appropriate for a scholarly audience, I think some words did not need to be so large and complex. For instance, as soon as I read the first sentence, I was already questioning what the word “cognizant” meant. I do like the structure though, and the word choice was nice. Logic--explains and supports the problem addressed in a problem-solving thesis. The body paragraphs support the problem, but the thesis needs to be stronger and more relevant to the topic. Mechanics-- the paper observes standard English conventions in spelling, grammar, punctuation, and documentation. There were only a few minor typos, and aside from those, the mechanics of the paper were executed well. Informal Peer Review: Something I really liked about this piece was: I liked your presentation of the various sides of the argument, I thought it was nice how you introduced details that were truly opposing your argument and could cause the audience to disagree with your side. I also like your topic in general. Something I found interesting is: I found it interesting that it is more expensive to use animals in research than it is synthetic skin. I would have thought it to be the exact opposite, hence why we use animals instead. Something I’d like to ask about this piece is: I would like to ask what the 3 R’s of moral animal experimentation are and why they are not being implemented today in animal testing. Reviewer: Catie Hall Peer Review Feedback Form Writer: Shelby Skelton Essay: The Ethics Behind Animal Testing To the best of your ability, using the assignment and grading rubric for this course, answer the questions below for your peer accordingly. Peer feedback in this class should be constructive, helpful, and supportive. When finding weak areas in a peer’s work, leave a comment or ask a question to help guide them in the improvement of that area. Clarity—the paper addresses the prompt, there is a clear and concise thesis statement, and an outline of what’s to come. Yes, and it does so very informatively. Could use a little emotion though robot ;) Coherence—the text is easy to understand. Key terms are defined, and a reader’s point of view is considered along with the writer’s perspective. Finally, is all I can say when it comes to this peer review shenanigans. Good shit Cohesion--the text is arranged efficiently and effectively. It has a chronological structure, follows a theme, and the organization fits the topic. Yes, yes, yes, berry gud Organization—the paper has a logical, thoughtful, and easy-to-follow structure. There is a thematic/rhetorical thread schema going through the paper. There are effective topic sentences and transitions. Great organization, I’m glad you kicked this one out of the ballpark as your rough drafts are concerned Development--each body paragraph: 1) provides adequate (quantity and quality) evidence; 2) develops key ideas thoroughly; and 3) moves the argument further along. I SAY, this paper is well written Style—the author’s writing is appropriate for the intended audience and for the assignment. The text is interesting to read and appropriately representative of a writer’s identity. It is very informative, and you have the evidence to back it up. I like it Flow-- the author’s particular selection of words, construction of sentences, arrangement of ideas, and varied usage of rhetorical strategies is engaging and appropriate for the intended audience. Damn good madam! Logic--explains and supports the problem addressed in a problem-solving thesis. Yez, iz nize, very nize Mechanics-- the paper observes standard English conventions in spelling, grammar, punctuation, and documentation. There are quite a bit of grammatical errors, but other than that the paper is good!