Unit 1: Levels of Organization I. II. III. IV. V. Introduction a. The study of the human body probably began with our earliest ancestors i. Mostly interested in injuries and illnesses ii. Superstition and mysticism 1. Led to discoveries and observations Anatomy and Physiology a. Anatomy – the branch of science that deals with the structure (morphology) of body parts; their forms and how they are organized b. Physiology – concerns the functions of body parts; what they do and how they do it. c. The topics of anatomy and physiology are difficult to separate because the stuctures of body parts are so closely associated with their functions. i. A particular body part’s function depends on the way the par is constructed— that is, how its subparts are organized ii. For example, the organization of the parts in the human hand with its long, jointed fingers make it easy to grasp objects 1. The hollow chambers of the heart are adapted to pump blood through tubular blood vessels 2. The shape of the mouth enables it to receive food 3. Teeth ar eshaped to break solid foods into small pieces d. In 2003, researches completed deciphering the human genome—that is, the biochemical instructions that run the human body Levels of Organization a. Basic Level of Organization i. Atoms, molecules, macromolecules, cells, organelles, tissues, organs, organ systems, organisms…and so on b. Body parts can be described in terms of different levels of organization, such as atomic differ in complexity level, molecular level, or the cellular level i. Furthermore, body part from one level to the next. Characteristics of Life a. Before beginning a more detailed study of anatomy and physiology, it is helpful to consider some of the trait s humans share with other organisms. i. Metabolism – the sum total of all of the chemical reactions in the body that break substances down and build them up 1. This includes: moving, eating, digesting, growing, making the sex, etc. Maintenance of Life a. Requirements of Organisms i. Water 1. Most abundant chemical in the body 2. Required for many metabolic processes 3. Transports substances within the body 4. Regulates body temperature ii. Foods 1. Provides the body with necessary chemicals (nutrients) in addition to water 2. Chemicals are then used for energy (calories) 3. Provides raw materials for building new living matter 4. Regulates vital chem rxns iii. Oxygen 1. Makes up about one-fifth of ordinary air 2. Used to release energy from food substances 3. Drives metabolic processes iv. Heat 1. A form of energy! 2. Product of metabolic rxns 3. Determines the rate of rxns 4. TEMPERATURE IS A MEASURE OF THE DEGREE OF HEAT v. Pressure 1. An application of force to something a. Atmospheric pressure i. Think about altitude sickness b. Hydrostatic pressure i. Think about swimming ii. Heart action produces blood pressure b. Although organisms require water, food, oxygen, heat, and pressure, these factors alone are not enough to ensure survival. i. Equilibrium ii. Quality of resources c. Health-care workers repeatedly monitor patients’ vital signs i. These are observable body functions that reflect essential metabolic activities ii. Assessment of vital signs includes measuring body temperature, blood pressure, oxygen, and water. iii. Absence of vital signs signifies death. 1. No spontaneous muscles and beating heart 2. No response to stimuli, 3. No reflexes a. Pupillary reflexes 4. Brain waves cease a. Flat electroencephalogram (EEG) signifies a lack of metabolic activity in the brain d. Homeostasis i. Body parts function only when the concentrations of water, nutrients, and oxygen and conditions of heat and pressure remain within certain narrow limits. ii. The body maintains homeostasis through a number of self-regulating control systems, or homeostatic mechanisms, that share the following components: 1. Receptors – provide information about specific conditions (stimuli) in the internal environment 2. Set point – tells what a particular value should be (such as body temperature at 37 degrees) 3. Effectors – cause responses that alter conditions in the internal environment iii. Homeostatic mechanisms work as follows: 1. Receptors measure deviations from the set point, 2. Effectors are activated that can return conditions toward normal 3. Conditions return toward normal, the deviation from the set point progressively lessons, and the effectors are gradually shut down a. This is called NEGATIVE FEEDBACK because the deviation from the set point is corrected (moves in the opposite or negative direction) b. This latter aspect is important because it prevents a correction from going too far c. Examples: Furnace, caffeine, Xanax, tolerance d. CHECK PG 6 – 7 e. Human Body Thermostat Example with Graphic iv. Organization of the Human Body 1. Body Cavities a. Axial – head, neck, and trunk b. Appendicular – upper and lower limbs c. Cranial cavity – le brain d. Vertebral canal – spinal cord e. Thoracic cavity – skin, skeletal (voluntary) muscles, and various bones f. Abdominopelvic cavity g. Viscera h. Diaphragm – broad, thin muscle that separates the thoracic cavity from the lower abdominopelvic cavity i. Mediastinum – separates the thoracic cavity into two comaprtments, which contain the right and left lungs i. The remaining thoracic viscera—heart, esophagus, trachea, and thymus—are located within the mediastinum j.