Name:
CHML211
Exp. 7 Recrystallization, Melting Point and HPLC of Analgesics
Max
10
20
20
50
Tech
Pre
In
Post
Score
Total Grade
PRE-LAB ASSIGNMENT: (EACH STUDENT will complete, print, and submit a copy at the beginning of the lab period.
Without a complete pre-lab assignment, you will not be allowed to perform the experiment, and will receive a zero
for the lab.) …..max score = 20 pts.
1.
Objective (In the provided space, write a brief purpose of the experiment in complete sentences, addressing all of the following points)



What techniques will be introduced in this experiment?
What goal will be accomplished using these techniques?
How will the efficiency of the method and the purity of the compounds be determined?
2. Chemical Structures (In the provided space, draw the chemical structures of all compounds below)
aspirin
acetaminophen
ethyl acetate
3. Physical Data (Complete the following table using MSDS sheets from the following link:
acetone
http://www.sigmaaldrich.com/united-states.html. Copy all
of the OSHA hazards using the hazard codes provided.)
Compound
acetone
ethyl acetate
aspirin
acetaminophen
bp
(Co)
XXX
XXX
mp
(Co)
XXX
XXX
d
(g/mL)
OSHA HAZARDS
XXX
XXX
4. Experimental Outline (In the space provided, give a brief description of the procedure that will be followed in this experiment in 10 lines or less.)
1
2
3
4
5
6
7
8
9
10
5. Pre-Lab Question (Answer the following question prior to lab.)
a.
The ideal solvent for a recrystallization is one that:
i. Dissolves a moderately large amount of the compound when hot.
ii. Does not react with the compound.
iii. Dissolves only a small amount of the compound when cool.
iv. Boils at a temperature below the compound’s melting point.
v. All of the above.