Cells and Their Environment Structure of the Plasma Membrane The plasma membrane (cell membrane) is made of two groups of organic molecules-phospholipids and proteins. A phospholipid is a molecule shaped like a head with two tails. The head is polar and the two tails are nonpolar. Polar head Nonpolar tails Water molecules form hydrogen bonds with the polar heads, but push away the nonpolar tails, thus forming a two-layer structure with the heads facing outward and the tails facing inward. This is the plasma membrane. The plasma membrane is fluid, like a soap bubble and has various proteins stuck in it. Outside of Cell Inside of Cell Channel protein Receptor protein Marker protein Cell Surface Proteins The proteins within the plasma membrane of cells are called cell surface proteins. There are several kinds. Channel proteins have a structure that makes them doughnut shaped, with a hole in the middle. Polar sugars, amino acids, ions, and other particles can pass through these channels. Receptor proteins transmit information from the world outside the cell to the cell’s interior. The outside part of a receptor protein fits only a particular type of molecule. If that molecule attaches to a receptor, the shape of the other end of the receptor is changed, thus passing “information” inside the cell. Channel protein Marker proteins have long carbohydrate arms attached to them that identify the cell to other cells. • Receptor Protein Marker protein with carbohydrate arm Moving Materials Into and Out of Cells Materials can move through the cell membrane without using any of the cell’s energy. This is called passive transport. One kind of passive transport is diffusion. Particles in a solution tend to move from an area of greater concentration to an area where there are less of them (a lesser concentration). This movement is called diffusion. Water molecule - will move into the cell Water also moves from a greater to a lesser concentration. When water travels across a membrane from a greater to a lesser concentration of water, this is called osmosis. Cell Solute molecule - will move out of the cell. Cell’s Environment • Water and Solution Concentrations Water Molecule Solute Molecule Hypotonic Solution- the environment’s solute concentration is less than inside the cell. Water will move into the cell. Hypertonic Solution- the environment’s solute concentration is greater than inside the cell. Water will move out of the cell. Isotonic Solution- the solute concentration is the same inside and outside the cell. Water movement into the cell equals movement out of the cell. No net water movement. · Facilitated Diffusion Facilitated diffusion is the movement of specific particles through a membrane by a channel protein. The molecule that is to be transferred locks onto the channel protein on the outer surface of the cell membrane and then passes through the channel to the inside of the cell. The plasma membrane is selectively permeable. It allows some particles to pass through and prevents the passage of other particles. Many of the selective protein channels through the plasma membrane are two-way channel proteins called pores. Different particles fit into different sized pores. · Plasma Membrane Interior of Cell Channel Protein Active Transport Cells must be able to take in molecules that are in low concentration outside of the cell. To do this, cells need to spend energy. These processes are called active transport. Sodium ions along with food molecules enter the cell through coupled channels. Energy from food molecules is used to drive Proton pumps that cause the production of ATP. ATP molecules drive Sodium-potassium pumps, which transport sodium ions back outside the cell. Proton pumps carry protons (H+ ions) across membranes to make ATP, the energy currency of the cell. The active transport of protons to make ATP is called chemiosmosis. Sodium-potassium pumps use some of the ATP produced by the proton pumps to build up a large concentration of Na+ ions outside of the cell. Coupled channels carry the sodium ions back into the cell, along with some food molecules, that cannot pass through the plasma membrane by themselves. · Endocytosis and Exocytosis Food particles that are too large to go through protein channels in the cell membrane enter the cell by endocytosis. In endocytosis, the cell surrounds and then engulfs the food particle. This requires energy. There are two kinds of endocytosis. If the material being engulfed is liquid, the endocytosis is called pinocytosis. If the material is solid, the process is called phagocytosis. · The opposite of endocytosis is exocytosis. Cells use this process to get rid of wastes. Gland cells dump hormones into the blood by exocytosis. Endocytosis 1. 2. 3. Exocytosis 1. 2. 3. How Cells Communicate Your cells communicate with each Indirect communication between other directly and indirectly to cells is done two ways--through the coordinate growth, development, endocrine system and the and other activities. nervous system. Direct communication happens The endocrine system between some cells. These cells communicates using chemicals have tiny openings in their cell called hormones. membranes called gap Nerve cells communicate using junctions, that let the cytoplasm chemicals called of the two cells join together. neurotransmitters. Special proteins on the cell’s Cell #1 cytoplasm Gap Junction surface, called receptors, signal the cytoplasm when a particular Cell Membrane particle has bumped into the cell’s surface. Cell Membrane · Cell #2 cytoplasm How Cells Receive Communications The binding of a signal particle Some channel proteins can be to a cell’s surface receptor can opened or closed. They are called influence the cell’s cytoplasm in gated channels. Gated channels one of three ways: may be opened either chemically or electrically. The receptor can become an Signal enzyme that chemically molecule Na+ changes molecules in the cell’s cytoplasm. Cell Membrane The receptor can create a Gated channel is closed. Cell cytoplasm second messenger which will Ions cannot enter. have an effect somewhere else in the cytoplasm. Signal molecule The receptor can open a channel through the plasma Na+ membrane. Neurotransmitters do this. Cell Membrane · Signal molecule changes shape of gate, which opens. Ions pass through gate to cytoplasm.