Ch. 3 Part 2 Cell Transport Movement Across Cell Membranes • Cell membranes are a barrier, but substances must be able to get in and out • 5 main methods of transport – Simple diffusion – Osmosis – Facilitated diffusion – Active transport – Vesicles Simple Diffusion • Molecules move from an area of high concentration to an area of low concentration (H → L) • Through cells – only lipid-soluble molecules (steroids) or very small molecules (O2, H2O, CO2) can do this • Only stop when equilibrium is reached Simple Diffusion Osmosis • Diffusion of water • Water is always looking to keep a balance between inside and outside the cell • 3 types of solutions result in osmosis – Hypotonic – Hypertonic – Isotonic Osmosis • Hypotonic – Concentration of solute is higher outside the cell than inside the cell – Water moves inward to balance – Cell size increases – animal cells can burst (lysis) • Hypertonic – Concentration of solute is lower outside the cell than inside the cell – Water moves outward to balance – Cell size decreases – shrivel up (crenation) • Isotonic – Concentration of solute is equal inside and outside – Water moves, but the balance remains – Cell size does not change Osmosis Facilitated Diffusion • Same as diffusion with help (facilitated) • This help is done by proteins • 2 types of proteins – Channel proteins • Form a pore or channel where ions can pass through • Many channels are gated and can be closed – Carrier proteins • Has a binding site for a specific molecule • Can move substances in and out Facilitated Diffusion Active Transport • Forces molecules to go from one side to the other, against concentrations • Must be performed with proteins • Must have energy to occur • Example: – Sodium-potassium pump Active Transport • Sodium-potassium pump – Essential for neural impulses to be sent – Pumps 3 sodium out of the cell – Pumps 2 potassium into the cell – This helps maintain the correct gradient of ions Vesicles • Exocytosis – Removes large molecules out of the cell by using vesicles (pouches) • Endocytosis – Brings large molecules into the cell using vesicles – Pinocytosis – cell drinking – Phagocytosis – cell eating Vesicles Transport Summary • Active transport – Moves materials from low to high – Goes against the concentration gradient – Energy required • Passive transport – Moves materials from high to low – Goes with the concentration gradient – No energy required Which is which? • Which types of transport are passive or active? • Which types of transport use proteins? • Simple diffusion? • Osmosis? • Facilitated diffusion? • Active transport? • Vesicles?