Supplementary Table 1: Questions related to symptoms of dry eye
(I)
Questions on irritation
How often did you experience the following in the last month?
A. Gritty or scratchy sensation in the eye
B. Burning or stinging sensation in the eye
C. Tearing excessively
D. Pain in the eyes in the middle of the night or upon waking up in the
morning
(II)
Questions on blurring of vision
How often did u experience the following in the last month?
E. Blurred vision
F. Blurred vision that fluctuates with blinking
G. Blurred vision that improves with artificial tears
(III)
Question on photophobia
H. How often did you experience discomfort in your eyes in the presence
of bright lights last month?
Supplementary Table 2: HADS and CES-D questionnaires
A. HADS Questionnaire
Anxiety
1. I feel tense or wound up
3 – Most of the time
2 – A lot of times
1 – From time to time
0 – Not at all
3. I get a sort of frightened feeling as if
3 – Very definitely and quite badly
something awful is about to happen
2 – Yes, but not too badly
1 – A little, but it doesn’t worry me
0 – Not at all
5. Worrying thoughts go through my
3 – Most of the time
mind
2 – A lot of times
1 – From time to time
0 – Only occasionally
7. I can seat at ease and feel relaxed
3 – Not at all
2 – Not often
1 – Usually
0 – Definitely
9. I get a sort of frightened feeling like
3 – Very often
butterflies in the stomach
2 – Quite often
1 – From time to time
0 – Not at all
11. I feel restless, as if I had to be on the
3 – Very much indeed
move
2 – Quite a lot
1 – Not very much
0 – Not at all
13. I get a sudden feeling of panic
3 – Very often indeed
2 – Quite often
1 – From time to time
0 – Not at all
Depression
2. I still enjoy the things I used to
3 – Hardly at all
2 – Only a little
1 – Not quite as much
0 – Definitely as much
4. I can laugh and see the funny side of
3 – Not at all
things
2 – Definitely not so much now
1 – Not quite as much now
0 – As much as I always could
6. I feel cheerful
3 – Not at all
2 – Not often
1 – Usually
0 – Most of the time
8. I feel as if I am slowed down
3 – Nearly all the time
2 – Very often
1 – From time to time
0 – Not at all
10. I have lost interest in my appearance
3 – Definitely
2 – I don’t take so much care as I should
1 – I may not take quite as much care
0 – I take just as much care as ever
12. I look forward with enjoyment to
3 – Hardly at all
things
2 – Definitely less than I used to
1 – A little less than I used to
0 – As much as I ever did
14. I can enjoy a good TV or radio
3 – Hardly at all
program or book
2 – Not often
1 – Sometimes
0 – Often
B. CES-D Questionnaire
1. I was bothered by things
0 – rarely or none of the time (less than 1 day)
that usually don’t bother me
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
2. I did not feel like eating;
0 – rarely or none of the time (less than 1 day)
my appetite was poor
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
3. I felt that I could not shake
0 – rarely or none of the time (less than 1 day)
off the blues even with the
1 – some or a little of the time (1 – 2 days)
help from my family or
2 – occasionally or a moderate amount of time (3 – 4
friends
days)
3 – most or all of the time (5 – 7 days)
4. I felt I was just as good as
0 – most or all of the time (5 – 7 days)
other people
1 – occasionally or a moderate amount of time (3 – 4
days)
2 – some or a little of the time (1 – 2 days)
3 – rarely or none of the time (less than 1 day)
5. I had trouble keeping my
0 – rarely or none of the time (less than 1 day)
mind on what I was doing
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
6. I felt depressed
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
7. I felt that everything I did
0 – rarely or none of the time (less than 1 day)
was an effort
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
8. I felt hopeful about the
0 – most or all of the time (5 – 7 days)
future
1 – occasionally or a moderate amount of time (3 – 4
days)
2 – some or a little of the time (1 – 2 days)
3 – rarely or none of the time (less than 1 day)
9. I thought my life had been
0 – rarely or none of the time (less than 1 day)
a failure
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
10. I felt fearful
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
11. My sleep was restless
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
12. I was happy
0 – most or all of the time (5 – 7 days)
1 – occasionally or a moderate amount of time (3 – 4
days)
2 – some or a little of the time (1 – 2 days)
3 – rarely or none of the time (less than 1 day)
13. I talked less than usual
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
14. I felt lonely
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
15. People were unfriendly
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
16. I enjoyed life
0 – most or all of the time (5 – 7 days)
1 – occasionally or a moderate amount of time (3 – 4
days)
2 – some or a little of the time (1 – 2 days)
3 – rarely or none of the time (less than 1 day)
17. I had crying spells
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
18. I felt sad
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
19. I felt that people disliked
0 – rarely or none of the time (less than 1 day)
me
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4
days)
3 – most or all of the time (5 – 7 days)
20. I could not get “going”
0 – rarely or none of the time (less than 1 day)
1 – some or a little of the time (1 – 2 days)
2 – occasionally or a moderate amount of time (3 – 4 days)
3 – most or all of the time (5 – 7 days)