Foundations of biology

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Unit 1
FOUNDATIONS OF BIOLOGY
Chapter 1
THE SCIENCE OF LIFE
SECTION 1 THE WORLD OF BIOLOGY
Objectives
 Relate biology to everyday life
 Describe importance of biology
 List characteristics of living things
 Summarize hierarchy of organization
 Distinguish between homeostasis &
metabolism, growth, development &
reproduction
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SECTION 1
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Vocabulary
Biology
Organization
Cell
Unicellular
Multicellular
Organ tissue
Organelle
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Vocabulary
Biological molecule
Homeostasis
Metabolism
Cell division
Development
Reproduction
Gene
BIOLOGY AND YOU
Biology: study of life
 Organized and scientific framework to answer
questions about natural world
 Biologist: studies how living things work,
interact with environment and change over
time
 Example: healthy foods, exercise, avoid getting
sick
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CHARACTERISTICS OF LIFE
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Name 5 living and 5 non-living things
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Criteria for living: 7 Characteristics
Organization (1 or more cells)
Response to stimulus
Homeostasis
Metabolism
Growth & development
Reproduction
Change over time
1.
2.
3.
4.
5.
6.
7.
1. ORGANIZATION AND CELLS
High degree of order within internal & external
parts.
 Unicellular: organism made of one cell.
 Example?
 Multicellular: organism made of multiple cells
 Example?
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1. ORGANIZATION AND CELLS
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Highest level of organization have organ systems: group
of specialized parts that carry out a specific function.
Organs: structures that carry out specialized jobs. Made
of tissues.
Tissues: groups of cells that have similar abilities and
follows the organ function. Made of cells
Cells: covered by membrane, contains all genetic
information. Has organelles
Organelles: tiny structures that help cell stay alive.
Contain biological molecules.
Biological molecules: Chemical compounds. Made of
atoms
Atoms: simplest particle of an element
2. RESPONSE TO STIMULI
Stimulus: physical/chemical change in
internal/external environment.
 Respond and react to changes
 Example: stimulus: bright light. Reaction?
 https://www.youtube.com/watch?v=h6evXswaQs
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3. HOMEOSTASIS
Maintain stable internal conditions
 Example: temperature, water content, nutrient
uptake.
 How do humans control body temperature?
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4. METABOLISM
Sum of all the chemical reactions that take in
and transform energy and materials from the
environment.
 Example: plants: photosynthesis. Mammals:
ingest and digest food.
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5. GROWTH AND DEVELOPMENT
Increase in size by dividing and enlarging cells.
 Crystals grow by accumulating more cells, not
by division and enlargement
 Cell division: forming of two new cells from an
existing cell
 Development: process of maturation. Involves
cell division and differentiation. And
specialization
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6. REPRODUCTION
Produce new organisms
 Not essential to survival of individual?
 Why is it important?
 Continuation of spp
 Pass on DNA, contains genes
 Sexual reproduction: recombines two organisms of
same spp
 Asexual reproduction: no combination, identical
offspring
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7. CHANGE OVER TIME
Evolution
 Organisms change and adapt over time
because the environment changes.
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HOMEWORK SECTION 1
SECTION 2 THEMES IN BIOLOGY
Objectives
 Identify three important themes that help
explain the living world
 Explain how life can be diverse, yet unified
 Summarize why evolution is an important
theme in biology
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SECTION 2
Vocabulary
 Domain
 Kingdom
 Ecology
 Ecosystem
 Evolution
 Natural selection
 Adaptation
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DIVERSITY AND UNITY OF LIFE
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_________________spp on Earth
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Many more remain to be identified
UNITY IN DIVERSITY OF LIFE
Themes:
 1. ___________________________
 2. ___________________________
 3. ___________________________
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 Represented
by __________________
 Model of relationships
 Similar sets of genes on ___________branches
TREE OF LIFE
THREE DOMAINS OF LIFE
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Domains: ______________________________
Kingdoms:
 Bacteria: ________________
 Archaea: ___________________
 Eukarya: _______________________________
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INTERDEPENDENCE OF ORGANISMS
Ecology: ________________________________
_______________________________________
 Ecosystems: ____________________________
_______________________________________
 Orgs depend on: _________________________
________________________________________
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EVOLUTION OF LIFE
Descent with modification, inherited
characteristics within a population changes so
new spp can develop.
 Explains ________________________________
_______________________________________.
 Explains ________________________________
________________________________________
 Explains ________________________________
________________________________________
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NATURAL SELECTION
Orgs with favourable traits are better able to
____________and _______________
 Adaptations: traits that improve an individuals
ability to ___________and _____________.
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HOMEWORK SECTION 2
SECTION 3 THE STUDY OF BIOLOGY
Objectives
 Outline the main steps in the scientific method
 Summarize how observations are used to form
hypotheses
 List the elements of a controlled experiment
 Describe how scientists use data to draw
conclusions
 Compare a scientific hypothesis and a scientific
theory
 State how communication in science helps prevent
dishonesty and bias
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SECTION 3
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Vocabulary
Scientific method
Observation
Hypothesis
Prediction
Experiment
Control group
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Vocabulary
Experimental group
Independent variable
Dependent variable
Theory
Peer review
SCIENCE AS A PROCESS
Scientific method: two important principles.
 1.______________________________________
________________________________________
 Example: lightning: not from Zues but from
electric charges in atmosphere
 2. Uniformity: ___________________________
_______________________________________.
 Example: ________________
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STEPS OF THE SCIENTIFIC METHOD
1. Observation: ____________________________
__________________________________________
 2. Hypothesis: ______________________________
 3. Prediction: _______________________________
__________________________________________
 4. Experiment: ______________________________
 5. Analysis: ________________________________
 6. Conclusion & Communication: arrive at a
judgment or opinion by ______________,
communicate results to ______________________
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1. OBSERVING AND ASKING QUESTIONS
Owls capture prey in the ___________
 How does an owl detect prey in the dark?
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2. FORMING A HYPOTHESIS
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________________
A)_______________
 B)___________________
 C)______________________
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3. PREDICTING
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___________________________________
A) the owl will pounce in either a __________or
____________room
 B) light room: ____________________________
dark room: ______________________________
________________________________________
 C) _____________________________________
________________________________________
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4. DESIGNING AN EXPERIMENT
Set up room with owl perch high on one side,
trap door on other side.
 ________________________________________
 Mouse ran silently, leaf made noise
 Half of trials in light room, half of trials in dark
room
 _________________________________
 View tape, measure position of owls strike
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PERFORMING THE EXPERIMENT
Controlled experiment: compares ______________
________ and _______________, only one variable
 Control group: normal standard against which
comparisons form EG can be made
 Experimental group: identical to CG except for
_______________________________.
 Experimenter _______________________________
 (Owl experiment: presence/absence of light)
 CG: light, EG: dark
 _____________________variable: respond variable
 (Owl experiment: distance of strike from head)
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TESTING THE EXPERIMENT
“Blind experiments”: ______________________
________________________________________
 Eliminates _____________
 Repeat experiments for
____________________________________
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5. COLLECTING AND ANALYZING DATA
Dependent variable gives quantitative data:
_____________________________________
 (Owl experiment: distance of strike from head
in cm)
 Scientists use and extend senses: ___________
_____________________
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ANALYZING AND COMPARING DATA
Organize data
 Goal: ______________________________,
support/fail to support hypothesis
 Statistics to help determine relationships
 Compare with other data
 _______________________________________
 _______________________________________
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DISTANCE BETWEEN OWL STRIKE & MOUSE/
OWL STRIKE AND LEAF
25
20
15
10
5
0
In light
in dark
Mouse
Leaf
6. DRAWING CONCLUSIONS
Light: greater accuracy at __________________
 Dark: greater accuracy at __________________
 Support _____________hypothesis, not vision
hypothesis
 Experiments only ______________
 Can’t ________hearing, maybe unknown smell
 Only ____________vision hypothesis
 More experimentation ____________________
________________________________
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MAKING INFERENCES
Conclusion made on the basis of _________
and _______________________rather than
direct observation
 Not directly testable
 Owl study: inferred that owl detects prey from
distance, not direct touch
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APPLYING RESULTS AND BUILDING MODELS
__________________________________
 Build models to ____________or
__________things
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1953 James Watson & Francis Crick use
cardboard and metal balls to build models of
______________
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Mathematical models are __________________
CONSTRUCTING A THEORY
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Theory according to scientists: _____________,
__________________principle that explains
observations and experimental data.
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Theory according to people: _______________,
“It’s just a theory”
COMMUNICATING IDEAS
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Publishing findings in ________________
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______________
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To _______________or _____________on topic
PUBLISHING A PAPER
Research paper has four sections
 _____________________
 ______________________
 ____________________
 _________________
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Peer review: experts anonymously read and
critique papers
 Prevents ________________
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HONESTY AND BIAS
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Prevent _____________________and ________
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Repeat experiments
CONFLICT OF INTEREST
Good reputation is invaluable
 Avoid ____________________________
 Example: owner of drug company should not
test drug’s safety and effectiveness
 Research group/__________________will test it
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__________________will keep scientists honest
HOMEWORK SECTION 3
SECTION 4 TOOLS AND TECHNIQUES
Objectives
 List the function of each of the major parts of a
compound light microscope
 Compare two kinds of electron microscopes
 Describe the importance of having the SI
system of measurement
 State some examples of good lab practice
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SECTION 4
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Vocabulary
Compound light
microscope
Eyepiece (ocular lens)
Objective lens
Stage
Light source
magnification
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Vocabulary
Nosepiece
Resolution
Scanning electron
microscope
Transmission electron
microscope
Metric system
Base unit
MICROSCOPES AS TOOLS
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Tools are objects used to __________________
of a task
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Microscopes extend human vision ___________
___________________
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Study __________________________________
LIGHT MICROSCOPES
Compound light microscope: shines light
_____________a specimen, has _______lenses
to magnify images.
 Mount the specimen on a ________________
 Specimen must be ____________
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LIGHT MICROSCOPES
4 major parts
 1. _________(_________): magnifies ___ times
 2. ___________lens: light passes through
specimen then through lens. Magnifies the
image. Specimens can be stained
 3. ______: platform that supports a slide
holding specimen
 4. Light source: __________________________
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MAGNIFICATION AND RESOLUTION
Magnification: ___________________________
_________________________
 Nosepiece: ______________________________
 most powerful objective lens 100×
 Power of magnification =
________________________________________
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MAGNIFICATION AND RESOLUTION
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Resolution: ______________________________
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2000× magnification image becomes _______
because of light’s properties
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___________________________
ELECTRON MICROSCOPES
Beam of ________produces an enlarged image
 __________________________
 Some even show contours of _____________
 Images in black and white, use computers to
add colour
 Specimen in vacuum chamber,
________________________________________
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SCANNING ELECTRON MICROSCOPE (SEM)
Beam of electrons _______specimen’s surface
 3D images of specimen’s ______________
 Specimen sprayed with fine __________coating
 Beam of electrons aimed at specimen
 Metal coating emits shower of electrons
 Electrons project onto fluorescent screen
 Image of ________________
 ______________× magnification
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TRANSMISSION ELECTRON MICROSCOPE (TEM)
Beam of electrons ______________thinly sliced
specimen
 Magnetic lenses _________and _________
image on screen
 Great resolution
 ____________× magnification
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UNITS OF MEASUREMENT
Common measurement system to compare
results, _______________________________
 _____________________________
 Decimal system based on _________________
 Official name: Système International d’Unités.
 French
 ___________________________________(SI)
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BASE AND OTHER UNITS
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_____ fundamental base units (Table below)
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Multiples of base units designated by ________
(table below)
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Derived units produced by _________________
relationships between 2base units/2derived
units (Table below)
SI BASE UNITS
SAFETY
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Hazards: chemical, physical, radiological,
biological.
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Examples?
GOOD LAB PRACTICE
Safe, common-sense habits
 Never work alone in a lab
 Safety symbols:
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