Molecules and Membranes Part 1: Biological Macromolecules Biological Macromolecules Built of repeating units: monomers Based on CARBON - rings and chains Made of primarily C, H, O, and N Monomers combine to make Polymers Macromolecules with many repeating units Biological Macromolecules Made by dehydration synthesis Uses energy Makes water Broken apart by hydrolysis Releases energy Uses water Carbohydrates sugars starches Lipids fats and oils Proteins Enzymes Structural Nucleic Acids DNA and RNA Carbohydrates Used for energy and structure Monomer Monosaccharides one carbon ring Disaccharides two carbon rings All are sugars used for energy NOTE: most sugars end in -ose Polysaccharides Carbohydrates Three or more carbon rings Often in branches or chains Starch Glucose storage in plants Glycogen Glucose storage in animals Cellulose Structure and support in plant cell walls, stems, branches Lipids Used for Energy storage, structure and hormones Monomers: 3 Fatty acids + Glycerol Other (varies) Insoluble in water nonpolar Lipids Fats saturated Only single bonds in fatty acid Oils unsaturated fats Double bonds in fatty acids Both are long term energy storage Lipids: Phospholipids Primary component of cell membranes 2 fatty acids, glycerol and a phosphate group Phosphate ‘head’ is polar, fatty acid ‘tails’ are nonpolar Phospholipids in Water Forms a phospholipid bilayer Polar heads towards water (hydrophilic) and nonpolar tails away from water (hydrophobic) Used for Proteins Structure Primary building blocks of organisms Enzymes regulate chemical reactions Monomer Amino acid carboxyl group , amino group , R group – variable Determines type of amino acid - 20 Hemoglobin: transports oxygen in blood Insulin: regulates glucose in blood Myocin and actin: muscle fibers INSULIN Common Proteins Keratin: hair and nails Collagen: support organs, plumps skin Keratin Enzymes: Proteins: Enzymes Catalyst for chemical reactions How it works: Denaturation Temperature and pH can alter the shape of an enzyme causing it not to work Nucleic Acids Used for: Genetic material DNA – deoxyribonucleic acid Information carriers and to control protein synthesis RNA – ribonucleic acid Monomer Nucleotides - phosphate group, nitrogen containing base and a pentose sugar Nucleic Acids: DNA and RNA NUCLEOTIDE RNA DNA Nucleic Acids: DNA and RNA DNA RNA FULL NAME Deoxyribonucleic acid Ribonucleic acid BASIC STRUCTURE 2 long twisting strands of nucleotides in the form of a "double helix" 1 single strand of nucleotides NUCLEOTIDE SUGAR Deoxyribose Ribose NITROGENOUS BASES guanine (G) cytosine (C) adenine (A) thymine (T) guanine (G) cytosine (C) adenine (A) uracil (U) LOCATION IN A CELL nucleus (the chromosomes) nucleus, in the cytoplasm, & at the ribosomes FUNCTION the hereditary material of a cell, directs & controls cell activities involved in protein synthesis Macromolecules Monomer Function and Examples Carbohydrate Monosaccharide Glucose: Energy or simple sugar Sucrose: Energy Starch: Plant Energy storage Glycogen: Animal Energy storage Cellulose: Plant Cell walls Lipid Gylcerol and 3 fatty acids Fat: Long term Energy storage Oils: Long term Energy storage Phospholipids: membranes Protein Amino acids Proteins: Structure Collagen: skin, internal support Hemoglobin: carries O2 in blood Keratin: hair and nails Actin and myosin: muscle Protein: Enzyme Insulin: regulates glucose in blood Nucleic acid Nucleotides DNA: genetic material RNA: protein synthesis Molecules gone wild – video molecules gone wild ppt crash course