CHAPTER 3 CELL DIVISION: DNA AND CHROMOSOMES WHAT IS DNA? • The genetic material in cells is called DNA – deoxyribonucleic acid. • It is a chemical that contains info for an organism’s growth and function. • Made of two strands of molecules that twist to look like a ladder – forming a double helix. WHERE IS DNA? • Most of the DNA in a cell is contained in its nucleus. • It is a mass of loose strands. • Constantly copied. • Before division, it is compacted into structures called chromosomes. CHROMOSOMES • A chromosome is made up of two identical chromatids that are held together in the center by a centromere. • Humans have 46 chromosomes, fruit flies have 8, and corn plants have 20. CELL DIVISION • Through cell division, one cell becomes two, two cells become four, and so on. • Essential for three function: growth, development, and repair. GROWTH • a large organism does not necessarily have larger cells than a small organism, it just has more cells. • Cells do grow, but there are limits to their size. • Remember, cells need a high surface area to volume ratio to function, and as it grows the ratio decreases. When it divides, the surface area of both new cells increases. GROWTH • Also, as a cell grows, its functions must increase. However, the amount of DNA to demand these functions remains the same. DEVELOPMENT • During development, cells become specialized to perform specific functions. • The cells may take on new shapes and structures to help them complete their task. REPAIR • Injuries are repaired through cell division. • When you have a cut in your skin, skin cells on either side of the cut divide and replicate. These new cells heal the wound. • As cells die and age, they need to be replaced. Some types of cells need to be replicated at a faster rate (like skin cells). CHAPTER 3 THE CELL CYCLE THE CELL CYCLE • The normal sequence of development and division of a cell. • Two phases: interphase and cell division. • Cell division is broken into mitosis and cytokinesis for eukaryotes (cells with nuclei). INTERPHASE • The part of the cell cycle during which a cell is not dividing. • The cell grows to be about 2x its size. • Engages in normal cell activities; such as transporting materials and cellular respiration. • Towards the end of this phase, DNA is copied exactly to prepare for cell division. CELL DIVISION • Mitosis is the part of the cell cycle when the cell divides; it is usually the shortest part of the cell cycle. • Cytokinesis is the division of the parent cell’s cytoplasm; it happens right after mitosis. • After these two processes occur, a “parent cell” becomes two identical “daughter cells” with a complete set of DNA. STEPS OF MITOSIS Step 1: Prophase • During this phase, the DNA goes from its loose form into chromosomes. • The membrane around the nucleus disappears. STEPS OF MITOSIS Step 2: Metaphase • During this phase, the chromosomes line up in the middle of the cell. • Hint: Metaphase = Middle STEPS OF MITOSIS Step 3: Anaphase • The chromosome is split into its two chromatids, and the chromatids move to opposite ends of the cell. STEPS OF MITOSIS Step 4: Telophase • A new nuclear membrane forms around each group of chromatids, and they return to their loose threadlike form. CYTOKINESIS In animal cells: • A fiber ring pinches the cell membrane until it is separated into two individual cells. In plant cells: • A cell plate grows between the two nuclei. The cell plate eventually becomes part of the cell wall for each of the new cells. AFTER CELL DIVISION • There are now two separate cells. • They are identical to each other, and to their parent cell. • They are small cells now, but will go through a period of growth. CHAPTER 3 SEXUAL AND ASEXUAL REPRODUCTION ASEXUAL REPRODUCTION • One organism produces one or more new organisms that are identical to itself and that live independently of it. • The offspring is genetically identical to its parent. BINARY FISSION • A form of asexual reproduction occurring in prokaryotes. • The parent splits in two, producing two independent daughter cells. • Algae, some yeast, and protozoans (paramecium) BUDDING • A form of asexual reproduction occurring in unicellular and multicellular organisms. • An organism develops little buds on its body, with each bud having identical DNA as the parent. • Some buds stay connected to the parent, but most detach once they reach a certain size. • Yeast, hydras, and kalanchoe REGENERATION • The process of new tissue growing at injured or lost limb sites. • A starfish can be cut in half, and each half will grow back to form two separate starfish. • A plant can regrow its cut stems. SEXUAL REPRODUCTION • If you grow a plant by cutting it, the new plant is identical to the parent plant. • If you grow a plant from a seed, it has genetic material from two parents. • Plants growing from seeds and animals growing from eggs are examples of this. • Results in greater diversity of living organisms.