Testosterone
Braden Harris
History of Testosterone
• A testicular action was linked to circulating blood fractions – now
understood to be a family of androgenic hormones. In the early
work on castration and testicular transplantation in fowl by Arnold
Arnold Adolph Berthold(1803–1861). Research on the action of
testosterone received a brief boost in 1889, when the Harvard
professor Charles-Eduard Brown-Sequard (1817–1894), then in
Paris, self-injected subcutaneously a “rejuvenating elixir” consisting
of an extract of dog and guinea pig testicle. He reported in The
Lancet that his vigor and feeling of well-being were markedly
restored but, predictably, the effects were transient, and likely
based on a placebo effect, and Brown-Sequard’s hopes for the
compound were dashed. Suffering the ridicule of his colleagues, his
work on the mechanisms and effects of androgens in human beings
was abandoned by Brown-Sequard and succeeding generations of
biochemists for nearly 40 years.
Testosterone is…
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The steroid hormone from the androgen gland.
Found in mammals reptiles and birds
Secreted from the testes of males and ovaries from females
Can be secreted from the adrenal glands
Plays a key role in the male development of the reproductive
organs
• Promotes things as muscle and hair growth as well as bone
mass
Make up of Testosterone
What Testosterone Does
• In charge of necessary sperm count in adults
• Regulates acute HPA (hyperthalamic pituitary
adrenal axis)
• Mental and physical energy
• Makes men selfish and want to punish other
men for being selfish towards them
Low Testosterone
• Reduced testosterone can play a major role in
the Fight or Flight dominance challenge
• May cause men to lack in sexual motivation
• Have a decrease in sperm count
• Make men less responsive to sexual contact
High Testosterone
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May cause high blood pressure
Overly high sperm count
More of a fight then flight attitude
Mood swings
Too much or abnormal muscle build-up
Connection to the Brian
• Due to the testosterone presence in males
they have larger brains on average then that
of females
• Due to the the larger amounts of testosterone
in men they are more likely to get aggravated
easier than girls
• Testosterone gives the brain the ability for it
feel aggression due to the levels in the body
Testosterone Problems
• Testosterone insufficiency (also termed
hypotestosteronism or hypotestosteronemia) is
an abnormally low testosterone production. It
may occur because of testicular dysfunction
(primary hypogonadism) or hypothalamicpituitary dysfunction (secondary hypogonadism)
and may be congenital or acquired. An acquired
form of hypotestosteronism is a decline in
testosterone levels that occurs by aging,
sometimes being called “andropause” in men, as
a comparison to the decline in estrogen that
comes with menopause in women.
The End!!!